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Context In the context of hospitalization for acute heart failure (AHF), patients’ characteristics and outcome depending on the department of management (cardiologic or cardiogeriatric) are unknown. The aims of this study were to determine the profile and the outcome (rehospitalizations at 90 days) of patients hospitalized for HF in the Val de Marne area, a district in the suburbs of Paris, depending on whether they were hospitalized in cardiology or in a specific cardiogeriatric centre; and to analyze the modes and the precipitating factors triggering rehospitalizations in the two type of centre. Methods We conducted the ICREX-94 observatory within seven French cardiologic departments and three specific cardiogeriatric departments in the Val de Marne district, France. Results 308 patients were hospitalized for AHF between October 2017 and January 2019. During the 3 months following discharge, 52 (17%) patients were rehospitalized for AHF. Compared with patients hospitalized in cardiogeriatric centre, patients from cardiologic department were younger (P Conclusion Compared to cardiogeriatric centres, AHF patients discharged from cardiologic centers had clinical differences, but we found that they had the same prognosis regarding AHF rehospitalization at 90 days.

Background Senile transthyretin amyloidosis (ATTRwt) occurs in elderly patients and leads to severe heart failure (HF). The mechanism of the disease involved cardiac and extra cardiac amyloid fibril infiltrations. Consequence of extracardiac infiltration on frailty has been poorly studied. Purpose Ours aims were to describe the frailty phenotype in ATTRwt cardiac amyloidosis (CA) patients, estimate its prevalence, and investigate associations between frailty parameters, and cardiac involvement severity and course of amyloid disease. Methods We prospectively assessed frailty, using multidimensional geriatric tools, in ATTRwt CA patients followed in the French Referral Center for CA, between April 2018 and June 2019. Results 36 patients (35 males, median age 82 years) with ATTRwt CA were included. One third of patients were in NYHA class III–IV, 39% had a left ventricular ejection fraction Table 1 ). CA severity was significantly associated (P ≤ 0.05) with numerous frailty parameters independently from age. Furthermore, poor motricity and balance impairment were also significantly associated with a longer course of amyloid disease ( Fig. 1 ). Conclusion Frailty was highly prevalent in ATTRwt CA patients. Some frailty parameters were significantly associated with a longer course of amyloid disease and CA severity independently from age. Taking in account frailty in ATTRwt assessment and management should improve their quality of life.