1. Brain
- Author
-
Valentina Berti, Alberto Pupi, and Lisa Mosconi
- Subjects
Pathology ,medicine.medical_specialty ,Radiation ,medicine.diagnostic_test ,Cerebrum ,business.industry ,General Medicine ,Fluorodeoxyglucose PET ,Emotional lateralization ,Normal variation ,medicine.anatomical_structure ,Positron emission tomography ,In vivo ,medicine ,Aging brain ,Radiology, Nuclear Medicine and imaging ,business ,Sex characteristics - Abstract
Brain 18F-fluorodeoxyglucose (18F-FDG) PET allows the in vivo study of cerebral glucose metabolism, reflecting neuronal and synaptic activity. 18F-FDG-PET has been extensively used to detect metabolic alterations in several neurologic diseases compared with normal aging. However, healthy subjects have variants of 18F-FDG distribution, especially as associated with aging. This article focuses on 18F-FDG-PET findings in so-called normal brain aging, and in particular on metabolic differences occurring with aging and as a function of people’s gender. The effect of different substances, medications, and therapy procedures are discussed, as well as common artifacts.
- Published
- 2014