1. Engineering Paper-Based Sensors for Zika Virus
- Author
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Oscar A. Negrete, Robert J. Meagher, and Koen K. A. Van Rompay
- Subjects
0301 basic medicine ,Paper ,Cas9 ,Zika Virus Infection ,Diagnostic test ,Paper based ,Zika Virus ,Biology ,Microfluidic Analytical Techniques ,Molecular diagnostics ,biology.organism_classification ,Virology ,Data science ,Southeast asia ,Zika virus ,03 medical and health sciences ,030104 developmental biology ,CRISPR ,Humans ,RNA, Viral ,Molecular Medicine ,CRISPR-Cas Systems ,Molecular Biology - Abstract
The emergence of Zika virus (ZIKV) infections in Latin America and Southeast Asia has created an urgent need for new, simple, yet sensitive, diagnostic tests. We highlight recent work using paper-based sensors coupled with CRISPR/Cas9 to detect ZIKV RNA as a new approach to achieve rapid development and deployment of field-ready diagnostics for emerging infectious diseases.
- Published
- 2016
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