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264 results on '"Zubizarreta A"'

4. Development of a model to predict combined antidepressant medication and psychotherapy treatment response for depression among veterans

Author

Bossarte, Robert M., Ross, Eric L., Liu, Howard, Turner, Brett, Bryant, Corey, Zainal, Nur Hani, Puac-Polanco, Victor, Ziobrowski, Hannah N., Cui, Ruifeng, Cipriani, Andrea, Furukawa, Toshiaki A., Leung, Lucinda B., Joormann, Jutta, Nierenberg, Andrew A., Oslin, David W., Pigeon, Wilfred R., Post, Edward P., Zaslavsky, Alan M., Zubizarreta, Jose R., Luedtke, Alex, Kennedy, Chris J., and Kessler, Ronald C.

Published
2023
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16. Surgical treatment of displaced proximal humerus fractures is associated with decreased 1-year mortality in patients aged 65 years and older: a retrospective study of Medicare patients.

Author

Duey, Akiro H., Stern, Brocha Z., Zubizarreta, Nicole, Galatz, Leesa M., Parsons, Bradford O., Poeran, Jashvant, and Cagle, Paul J.

Abstract

Proximal humerus fracture (PHF) is a risk factor for 1-year mortality. This study aimed to determine if surgery is associated with lower mortality compared to nonoperative treatment following PHF in older patients. This retrospective cohort study used the Medicare Limited Data set. Patients aged 65 years and older with a PHF diagnosis in 2017-2020 were included. Treatment was classified as nonoperative, open reduction internal fixation (ORIF), total shoulder arthroplasty (TSA), or hemiarthroplasty. Multivariable logistic regression models examined (a) predictors of treatment type and (b) the association of treatment type with 1-year mortality, adjusting for patient demographics, comorbidities, frailty, and fracture severity among other variables. A subgroup analysis examined how the relationship between treatment type and 1-year mortality varied based on fracture severity. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) are reported. In total, 49,072 patients were included (mean age = 76.6 years, 82.3% female). Most were treated nonoperatively (77.5%), 10.9% underwent ORIF, 10.6% underwent TSA, and 1.0% underwent hemiarthroplasty. Examples of factors associated with receipt of operative (versus nonoperative treatment) included worse fracture severity and lower frailty. The 1-year mortality rate after the initial PHF diagnosis was 11.0% for the nonoperative group, 4.0% for ORIF, 5.2% for TSA, and 6.0% for hemiarthroplasty. Compared to nonoperative treatment, ORIF (aOR 0.55; 95% CI [0.47, 0.64]; P <.001) and TSA (aOR 0.59; 95% CI [0.50, 0.68]; P <.001) were associated with decreased odds of 1-year mortality. In the subgroup analysis, ORIF and TSA were associated with a lower 1-year mortality risk for 2-part and 3-/4-part fractures. Compared to nonoperative treatment, surgery (particularly TSA and ORIF) was associated with a decreased odds of 1-year mortality. This relationship remained significant for 2-part and 3-/4-part fractures after stratifying by fracture severity. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Association between timing of initiating supervised physical rehabilitation after rotator cuff repair and incidence of repeat repair and capsulitis: a population-based analysis.

Author

Stern, Brocha Z., Zubizarreta, Nicole, Anthony, Shawn G., Poeran, Jashvant, and Gladstone, James N.

Abstract

There is limited consensus on the optimal time to initiate supervised physical rehabilitation after a rotator cuff repair (RCR). We examined whether timing of initiating supervised physical rehabilitation was associated with repeat RCR or development of adhesive capsulitis within 12 months postoperatively in an observational cohort of commercially insured adults. This retrospective cohort study used the IBM MarketScan Commercial Claims and Encounters Database. We included adults aged 18-64 who underwent a unilateral outpatient RCR between 2017 and 2020 and initiated supervised physical rehabilitation 1-90 days postoperatively. Multivariable logistic regression models examined the adjusted association between time of initiating supervised physical rehabilitation (1-13, 14-27, 28-41, and 42-90 days postoperatively) and each of the primary outcomes: repeat RCR and capsulitis. In a sensitivity analysis, time to rehabilitation was alternatively categorized using a data-driven approach of quartiles (1-7, 8-16, 17-30, and 31-90 days postoperatively). We report adjusted odds ratios (OR). Among 33,841 patients (86.7% arthroscopic index RCR), the median time between index RCR and rehabilitation initiation was 16 days (interquartile range 7-30), with 39.9% initiating rehabilitation at 1-13 days. Additionally, 2.2% underwent repeat RCR within 12 months, and 12-month capsulitis was identified in 1.9% of patients. There were no significant associations between timing of initiating rehabilitation and 12-month repeat RCR (OR 0.85-0.93, P =.18-.49) or 12-month capsulitis (OR 0.83-0.94, P =.22-.63). Lack of associations between timing and outcomes was supported in sensitivity analyses. Timing of initiating rehabilitation was not significantly associated with adverse outcomes after RCR. The finding of no increased odds of repeat RCR or capsulitis with the earliest timing may support earlier initiation of rehabilitation to accelerate return to daily activities. Findings should be replicated in another dataset of similarly-aged patients. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Organ at risk delineation for radiation therapy clinical trials: Global Harmonization Group consensus guidelines

Author

Mir, Romaana, Kelly, Sarah M., Xiao, Ying, Moore, Alisha, Clark, Catharine H., Clementel, Enrico, Corning, Coreen, Ebert, Martin, Hoskin, Peter, Hurkmans, Coen W., Ishikura, Satoshi, Kristensen, Ingrid, Kry, Stephen F., Lehmann, Joerg, Michalski, Jeff M., Monti, Angelo F., Nakamura, Mitsuhiro, Thompson, Kenton, Yang, Huiqi, Zubizarreta, Eduardo, Andratschke, Nicolaus, and Miles, Elizabeth

Published
2020
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29. Quality of radiotherapy services in post-Soviet countries: An IAEA survey

Author

Rosenblatt, Eduardo, Fidarova, Elena, Ghosh, Sunita, Zubizarreta, Eduardo, Unterkirhere, Olga, Semikoz, Natalia, Sinaika, Valery, Kim, Viktor, Karamyan, Nerses, Isayev, Isa, Akbarov, Kamal, Lomidze, Darejan, Bondareva, Oksana, Tuzlucov, Piotr, Zardodkhonova, Manzura, Tkachev, Sergey, Kislyakova, Marina, Alimov, Jamshid, Pidlubna, Tetiana, Barton, Michael, and Mackillop, William

Published
2018
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38. Did the COVID-19 Pandemic Coincide With an Increase in Osteonecrosis as Indication for Total Hip Arthroplasty in Older Patients?

Author

Okewunmi, Jeffrey O., Duey, Akiro H., Zubizarreta, Nicole, Kodali, Hanish, Poeran, Jashvant, Hayden, Brett L., Moucha, Calin S., and Chen, Darwin D.

Abstract

Osteonecrosis of the femoral head is a common indication for total hip arthroplasty (THA). It is unclear to what extent the COVID-19 pandemic has impacted its incidence. Theoretically, the combination of microvascular thromboses and corticosteroid use in patients who have COVID-19 may increase the risk of osteonecrosis. We aimed to (1) assess recent osteonecrosis trends and (2) investigate if a history of COVID-19 diagnosis is associated with osteonecrosis. This retrospective cohort study utilized a large national database between 2016 and 2021. Osteonecrosis incidence in 2016 to 2019 was compared to 2020 to 2021. Secondly, utilizing a cohort from April 2020 through December 2021, we investigated whether a prior COVID-19 diagnosis was associated with osteonecrosis. For both comparisons, Chi -square tests were applied. Among 1,127,796 THAs performed between 2016 and 2021, we found an osteonecrosis incidence of 1.6% (n = 5,812) in 2020 to 2021 compared to 1.4% (n = 10,974) in 2016 to 2019; P <.0001. Furthermore, using April 2020 to December 2021 data from 248,183 THAs, we found that osteonecrosis was more common among those who had a history of COVID-19 (3.9%; 130 of 3,313) compared to patients who had no COVID-19 history (3.0%; 7,266 of 244,870); P =.001). Osteonecrosis incidence was higher in 2020 to 2021 compared to previous years and a previous COVID-19 diagnosis was associated with a greater likelihood of osteonecrosis. These findings suggest a role of the COVID-19 pandemic on an increased osteonecrosis incidence. Continued monitoring is necessary to fully understand the impact of the COVID-19 pandemic on THA care and outcomes. [ABSTRACT FROM AUTHOR]

Published
2023
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