218 results on '"Zheng, Yu-Guo"'
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2. Hydrophobic substrate binding pocket remodeling of echinocandin B deacylase based on multi-dimensional rational design
3. Structure-guided directed evolution of deacetylase leads to increased specificity of chloroacetamides and effective production of chloroamines
4. Designing a novel (R)-ω-transaminase for asymmetric synthesis of sitagliptin intermediate via motif swapping and semi-rational design
5. Efficient synthesis of D-pantolactone in monophase and organic-aqueous biphase reaction biosystem using a novel conjugated polyketide reductase based on integrated substrate pocket alteration
6. Constructing a continuous-flow bioreactor with co-immobilized KmAKR and BmGDH for synthesizing tert-butyl 6-cyano-(3R,5R)-dihydroxyhexanoate
7. Tuning an efficient Escherichia coli whole-cell catalyst expressing l-pantolactone dehydrogenase for the biosynthesis of d-(−)-pantolactone
8. Hot spot-based engineering of ketopantoate hydroxymethyltransferase for the improvement of D-pantothenic acid production in Escherichia coli
9. Reaction-kinetic model-guided biocatalyst engineering for dual-enzyme catalyzed bioreaction system
10. Re-designing Escherichia coli for high-yield production of β-alanine by metabolic engineering
11. Development of a new chemo-enzymatic catalytic route for synthesis of (S)− 2-chlorophenylglycine
12. Enhanced catalytic activity of recombinant transaminase by molecular modification to improve L-phosphinothricin production
13. Combining fermentation to produce O-succinyl-l-homoserine and enzyme catalysis for the synthesis of l-methionine in one pot
14. Comparative proteome analysis of Actinoplanes utahensis grown on various saccharides based on 2D-DIGE and MALDI-TOF/TOF-MS
15. Improvement of pyrroloquinoline quinone-dependent d-sorbitol dehydrogenase activity from Gluconobacter oxydans via expression of Vitreoscilla hemoglobin and regulation of dissolved oxygen tension for the biosynthesis of 6-(N-hydroxyethyl)-amino-6-deoxy-α-l-sorbofuranose
16. Synergetic degradation of waste oil by constructed bacterial consortium for rapid in-situ reduction of kitchen waste
17. O-Succinyl-l-homoserine overproduction with enhancement of the precursor succinyl-CoA supply by engineered Escherichia coli
18. One-step eantioselective bioresolution for (S)-2-chlorophenylglycine methyl ester catalyzed by the immobilized Protease 6SD on multi-walled carbon nanotubes in a triphasic system
19. Enzyme cascade for biocatalytic deracemization of D,L-phosphinothricin
20. Tuning amino acid dehydrogenases with featured sequences for L-phosphinothricin synthesis by reductive amination
21. Regulation of homoserine O-succinyltransferase for efficient production of L-methionine in engineered Escherichia coli
22. Asymmetric synthesis of l-phosphinothricin using thermostable alpha-transaminase mined from Citrobacter koseri
23. Synergistic improvement of PQQ-dependent D-sorbitol dehydrogenase activity from Gluconobacter oxydans for the biosynthesis of miglitol precursor 6-(N-hydroxyethyl)-amino-6-deoxy-α-L-sorbofuranose
24. Efficient biosynthesis of (R)-3-amino-1-butanol by a novel (R)-selective transaminase from Actinobacteria sp.
25. Separation and purification of l-methionine from E. coli fermentation broth by macroporous resin chromatography
26. Whole cell immobilization of refractory glucose isomerase using tris(hydroxymethyl)phosphine as crosslinker for preparation of high fructose corn syrup at elevated temperature
27. Biocatalytic production of (S)-2-aminobutanamide by a novel d-aminopeptidase from Brucella sp. with high activity and enantioselectivity
28. Chiral diol t-butyl 6-cyano-(3R,5R)-dihydroxylhexanoate synthesis catalyzed by immobilized cells of carbonyl reductase and glucose dehydrogenase co-expression E. coli
29. Efficient chemoenzymatic synthesis of gabapentin by control of immobilized biocatalyst activity in a stirred bioreactor
30. Enhanced activity of Thermomyces lanuginosus lipase by site-saturation mutagenesis for efficient biosynthesis of chiral intermediate of pregabalin
31. Activity improvement of a Kluyveromyces lactis aldo-keto reductase KlAKR via rational design
32. Cloning, expression and enzymatic characterization of an aldo-keto reductase from Candida albicans XP1463
33. An enzymatic method for determination of azide and cyanide in aqueous phase
34. Biochemical characterization and biosynthetic application of a halohydrin dehalogenase from Tistrella mobilis ZJB1405
35. Preparative separation of echinocandin B from Aspergillus nidulans broth using macroporous resin adsorption chromatography
36. Stereoselective determination of 2-benzamidomethyl-3-oxobutanoate and methyl-2-benzoylamide-3-hydroxybutanoate by chiral high-performance liquid chromatography in biotransformation
37. Enhancement of (S)-2,3-dichloro-1-propanol production by recombinant whole-cell biocatalyst in n-heptane–aqueous biphasic system
38. Key residues responsible for enhancement of catalytic efficiency of Thermomyces lanuginosus lipase Lip revealed by complementary protein engineering strategy
39. Industrial production of chiral intermediate of cilastatin by nitrile hydratase and amidase catalyzed one-pot, two-step biotransformation
40. Enantioselective synthesis of (S)-3-cyano-5-methylhexanoic acid by a high DMSO concentration tolerable Arthrobacter sp. ZJB-09277
41. Concurrent obtaining of aromatic (R)-2-hydroxyacids and aromatic 2-ketoacids by asymmetric oxidation with a newly isolated Pseudomonas aeruginosa ZJB1125
42. Efficient production of S-(+)-2-chlorophenylglycine by immobilized penicillin G acylase in a recirculating packed bed reactor
43. Production of (R)-epichlorohydrin from 1,3-dichloro-2-propanol by two-step biocatalysis using haloalcohol dehalogenase and epoxide hydrolase in two-phase system
44. Improvement of nitrilase production from a newly isolated Alcaligenes faecalis mutant for biotransformation of iminodiacetonitrile to iminodiacetic acid
45. Isolation of brefeldin A from Eupenicillium brefeldianum broth using macroporous resin adsorption chromatography
46. Characterization of a newly isolated strain Rhodococcus erythropolis ZJB-09149 transforming 2-chloro-3-cyanopyridine to 2-chloronicotinic acid
47. Enantioselective hydrolysis of diethyl 3-hydroxyglutarate to ethyl ( S)-3-hydroxyglutarate by immobilized Candida antarctica lipase B
48. Enhanced biotransformation of ( R, S)-mandelonitrile to ( R)-(−)-mandelic acid with in situ production removal by addition of resin
49. Chapter 5 - Enzyme engineering strategies to confer thermostability
50. Microbial biomass production from rice straw hydrolysate in airlift bioreactors
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