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In this paper, a polarization-independent chain Huygens' metasurface is proposed. It is polarization multiplexing of two chain structures. Owing to the polarization-independent property, it can be conveniently applied to design double-layer dual-polarized transmitarray antennas (TAAs) with low profile. The measured results show that, for the designed low-profile dual-polarized TAA, its peak gain is 29.7 dBi at 28 GHz with aperture efficiency of 48.9 %, and the 3-dB gain bandwidths is 8.8 %. With the F/D ratio of only 0.36, the proposed low-profile dual-polarized TAA based on the chain Huygens' metasurface has critical applications in antenna engineering. [ABSTRACT FROM AUTHOR]

In this paper, a shared-aperture transmissive/reflective bi-functional metasurface is proposed. On metasurfaces, antisymmetric dipole pairs as transmissive elements and symmetric dipole pairs as reflective elements are interleaved in orthogonal polarization. By utilizing Huygens' resonance, the metasurface can achieve near full phase coverage for orthogonally polarized transmitted and reflected wave. Then the bi-functional metasurface is used for the design of transmitarray (TA)/reflectarray (RA) bi-functional antenna. The measured results show that, for TA, the maximum gain is 30.26 dBi with antenna efficiency of 45.6 % and the 3-dB gain bandwidth is 26.3–29.3 GHz (10.79 %), and for RA, the maximum gain is 30.29 dBi with antenna efficiency of 45.7 % and the 3-dB gain bandwidth entirely covers the frequency region of 26–30 GHz. The bi-functional metasurface has important applications in the field of antenna engineering. [ABSTRACT FROM AUTHOR]

Ceramide synthases (CerSs) catalyze the formation of ceramides from sphingoid bases and acyl-CoA substrates. Increasing evidence suggests that cancer cells generally exhibit altered sphingolipid metabolism in the tumorigenesis of multiple cancers. However, there is no evidence that CerSs are associated with pancreatic ductal carcinoma (PDAC). In the present study, we examined CerS expression in clinical tissue and conducted data mining to investigate the clinical significance of CerSs in the TCGA-PAAD database. We found that high CerS6 expression positively correlated with progression and predicted worse prognosis in PDAC patients, establishing CerS6 as a potential biomarker for PDAC. Furthermore, CerS6 promoted cell proliferation, colony formation and invasion by producing C16-ceramide and was required for tumor formation. Mechanistically, AKT1 interacted with and phosphorylated FOXP3 at S418, which decreased the binding of FOXP3 to the CERS6 promoter and in turn induced CerS6 expression by reconstituting an activated state on the CERS6 promoter. The AKT1/FOXP3 axis mediated the CerS6 expression and promoted p53 mutant pancreatic tumorigenesis by producing excessive C16-ceramide, which induced the accumulation of mutant p53. Thus, our study explores the relationship between PI3K/AKT signaling and sphingolipid metabolism, revealing an oncogenic role for CerS6, which may represent a potential target for PDAC treatment. [ABSTRACT FROM AUTHOR]

We theoretically study the interface states of liquid surface waves propagating over the heterojunctions formed by a bottom with one-dimensional periodic undulations. By considering the periodic structure as a homogeneous one, our systematic study shows that the signs of the effective depth and gravitational acceleration are opposite within the band gaps whether the structure is symmetric or not. Those effective parameters can be used to predict the interface states which could amplify the amplitudes of liquid surface waves. These phenomena provide new opportunities to control the localization of water-wave energy. • We theoretically studied the propagation of liquid surface waves over a bottom with a one-dimensional periodic undulation. • Our study shows that the signs of the effective depth and gravitational acceleration are opposite within the band gaps. • Those effective parameters can be used to predict the interface states. [ABSTRACT FROM AUTHOR]

Abstract: A multichannel double-polarization bandpass optical filter, which has the performance of variable channel interval, is theoretically proposed. The filter consists of a stack of two one-dimensional photonic crystals (1D PCs). Based on the resonant couple of evanescent waves localized at the interfaces between neighboring layers, the linear transmission properties of the filter are numerically simulated by the transfer matrix method. The simulation results show that channel number of the filter can be changed by varying the thickness of the middle layer in the centrosymmetric 1D PC structure, while the bandwidth and wavelength of the channel can be adjusted by the incident angle of light. This work may be helpful in designing multichannel double-polarization bandpass optical filter in optical communication systems. [Copyright &y& Elsevier]