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Three new 3,4- seco -cycloartane triterpenoids ( 1 - 3 ), including an unusual C-1 oxygenated 3,4- seco -cycloartane triterpenoid lactone ( 3 ), along with six known triterpenoids, were isolated from 95% ethanol extract of the flower of Gardenia jasminoides . Their structures were determined by spectroscopic methods, especially 2D NMR and HRESIMS techniques. Compounds 3 , 4 ( dikamaliartane D ) , and 7 (ursolic acid) showed promising cytotoxic activity against HepG2 human hepatocellular carcinoma cell line with IC 50 values of 9.3, 27.7, and 39.3  μ M, respectively. [ABSTRACT FROM AUTHOR]

The CdS shows high selectivity on H 2 for photocatalytic lactic acid decomposition. However, the low efficiency caused by ultrafast charge recombination was not well addressed. Herein, MoS 2 /CdS nanoheterostructure with intimate contact interface was synthesized in-situ and used as an efficient photocatalyst for H 2 generation. The optimum H 2 generation rate of MoS 2 /CdS is 45.20 mmol g−1 h−1 which significantly boosts the activity of CdS (0.27 mmol g−1 h−1) by more than 167 folds. Band alignment of MoS 2 and CdS promoting charge transfer and separation contributes to the enhanced catalytic activity, which was well verified by multiple characterization approaches. [Display omitted] • The MoS 2 /CdS was synthesized by using a facile solvothermal approach. • The optimized MoS 2 /CdS exhibits an H 2 evolution rate of 45.20 mmol g−1 h−1. • The good performance is ascribed to the construction of well-defined heterostructure. • The photocatalytic mechanism was carefully analyzed. [ABSTRACT FROM AUTHOR]

Activity and stability are two scientific issues of concern in catalyst design and synthesis. In this study, supported (CoS/CdS) and encapsulated (CdS@CoS) catalysts were synthesized with controlled variations in solvent. Remarkably, the CoS/CdS exhibited higher activity, achieving an impressive average H 2 generation rate of 29.26 mmol g−1 h−1 for the optimized sample. Conversely, the CdS@CoS demonstrated superior stability, showing no significant activity decline over a 20-h period. These findings highlight the importance of the cocatalyst deposition state in affecting the photocatalytic performance of catalysts. This research provides valuable insights for the synthesis of photocatalysts. [Display omitted] • The controllable synthesis of CoS/CdS and CdS@CoS heterostructures was achieved. • The CoS/CdS demonstrated high activity, whereas the CdS@CoS exhibited long-term stability. • The impact of the deposition state of CoS on catalytic performance was examined. • The photocatalytic mechanism was detailedly analyzed. [ABSTRACT FROM AUTHOR]

Abstract Five undescribed cycloartane triterpenoids, including two cycloartane trinor-triterpenoids, were isolated from a 70% ethanol extract of the whole plant of Actaea vaginata (Ranunculaceae), together with thirteen known cycloartane triterpenoids. Their structures were determined by spectroscopic techniques and quantum chemical calculations for intramolecular noncovalent interactions with reduced density gradient method. All compounds were evaluated for their anti-inflammatory effects by a lipopolysaccharide (LPS)-stimulated nitric oxide (NO) production model in RAW264.7 macrophage cells, and some showed potent inhibitory effects with IC 50 values ranging from 5.0 to 24.4 μ M. Further mechanism studies showed that one compound dose-dependently suppressed LPS-induced NO production and pro-inflammatory cytokines secretion, and decreased the expression of iNOS, through inhibiting NF- κ B activation. Graphical abstract Five undescribed cycloartane triterpenoids were identified from Actaea vaginata. Compound 3 suppressed NO production and the expression of pro-inflammatory cytokines and iNOS in RAW264.7 cells. Image 1 Highlights • Five undescribed cycloartane triterpenoids were identified from Actaea vaginata. • Two compounds represent the first examples of cycloartane trinor-triterpenoids. • A reduced density gradient calculation was applied to determine the configuration. • Anti-inflammatory activity through inhibiting NF-κB activity were discussed. [ABSTRACT FROM AUTHOR]

In this work, two new three-dimensional Co(II) metal-organic frameworks (MOFs), {[Co 2 (TFBA)(4,4′-bpy)H 2 O]·5DMF·7H 2 O} n (CoMOF-1) and {[Co 2 (TFBA)(bpen)H 2 O] ·6DMF·6H 2 O } n (CoMOF-2) (H 3 TFBA = tris(3′-F-4′-carb oxybiphenyl)amine, 4,4′-bpy = 4,4′-bipyridine, bpen = trans -1,2-bis(4-pyridyl)ethene) were constructed by a solvothermal method. Both CoMOF-1 and CoMOF-2 displayed similar 3D frameworks with the 2, 3, 4, 6-c net topology based on dinuclear [Co 2 O 8 ] units. The powder X-ray diffraction (PXRD) results and thermogravimetric analysis (TGA) proved that CoMOF-1 and CoMOF-2 have good structural and thermal stability. As we expected, the luminescence sensing investigations demonstrated that CoMOF-1 and CoMOF-2 could be considered as promising luminescent sensors toward Cu2+, Fe3+ and Cr 2 O 7 2− ions via a quenching effect, with high sensitivity and good reusability. Additionally, the possible luminescent quenching reasons were systematically studied by UV spectroscopy, X-ray photoelectron spectroscopy (XPS), IR spectra and PXRD patterns. [Display omitted] In this work, two new three-dimensional Co(II) metal-organic frameworks (MOFs), {[Co 2 (TFBA)(4,4′-bpy)H 2 O]·5DMF·7H 2 O} n (CoMOF-1) and {[Co 2 (TFBA)(bpen)H 2 O] ·6DMF·6H 2 O } n (CoMOF-2) (H 3 TFBA = tris(3′-F-4′-carb oxybiphenyl)amine, 4,4′-bpy = 4,4′-bipyridine, bpen = trans -1,2-bis(4-pyridyl)ethene) were constructed by a solvothermal method. Both CoMOF-1 and CoMOF-2 displayed similar 3D frameworks with the 2, 3, 4, 6-c net topology based on dinuclear [Co 2 O 8 ] units. The powder X-ray diffraction (PXRD) results and thermogravimetric analysis (TGA) proved that CoMOF-1 and CoMOF-2 have good structural and thermal stability. As we expected, the luminescence sensing investigations demonstrated that CoMOF-1 and CoMOF-2 could be considered as promising luminescent sensors toward Cu2+, Fe3+ and Cr 2 O 7 2− ions via a quenching effect, with high sensitivity and good reusability. Additionally, the possible luminescent quenching reasons were systematically studied by UV spectroscopy, X-ray photoelectron spectroscopy (XPS), IR spectra and PXRD patterns. [ABSTRACT FROM AUTHOR]