Search

Your search keyword '"Teng, Yue"' showing total 150 results
Start Over Author "Teng, Yue" Publisher elsevier b.v.
150 results on '"Teng, Yue"'

38. Axial stress-strain behavior of high-strength concrete confined by circular thin-walled steel tubes

Author

Liu, Jiepeng, Teng, Yue, Zhang, Yusong, Wang, Xuanding, and Chen, Y. Frank

Subjects
High strength concrete -- Analysis -- Chemical properties -- Mechanical properties, Steel tube -- Usage, Business, Construction and materials industries
Abstract

ABSTRACT The axial stress-strain behavior of high-strength concrete confined by circular thin-walled steel tube was experimentally investigated. Specifically, 18 column specimens with the key parameters of concrete compressive strength and [...]

Published
2018

48. Pasteurized Akkermansia muciniphila mitigates 5-FU-induced intestinal mucositis in tumor-bearing mice through suppression of the cGAS-STING pathway and epithelial cell apoptosis.

Author

Teng, Yue, Li, Jiahui, Yan, Chunhong, Wang, Ailing, Ren, Xiaomeng, and Xia, Xiaodong

Abstract

The aim of this study was to examine whether pasteurized Akkermansia muciniphila (pAkk) could protect mice from chemotherapy-induced mucositis (CIM) in tumor-bearing mice. Mice were pretreated with pAkk and then treated with 5-fluorouracil (5-FU). pAkk mitigates symptoms of 5-FU-induced CIM, including slowing the rate of weight loss (14.2%) and increasing the villus height to crypt depth ratio (1.54%) in the ileum, while not impacting the antitumor efficacy of 5-FU. Furthermore, pAkk diminished the levels of proteins associated with apoptosis, including Bax, caspase-3, and Bcl-2, both in vivo and in vitro , and decreased the number of TUNEL-positive cells. pAkk further alleviated the disruption of cell barrier function and inflammation induced by 5-FU in a Caco-2/RAW264.7 co-culture model. Further exploration revealed that the cGAS-STING signaling pathway plays a crucial role in improving CIM by pAkk, with the expression of its related proteins being reversed upon pAkk treatment. The protective effect of pAkk was partially nullified after using a STING activator, further confirming that pAkk exerts its function at least partly through cGAS-STING signaling pathway. These findings provide support for developing Akkermansia muciniphila- based strategies to mitigate chemotherapy-related intestinal toxicity for patients with cancer. [Display omitted] • PAkk alleviates mucositis without affecting anti-tumor efficacy of 5-FU in vivo. • PAkk inhibits 5-FU-induced intestinal epithelial cell apoptosis in vitro and in vivo. • PAkk restores intestinal damage through cGAS-STING pathway in vitro and in vivo. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

50. The reconstructive strategy for pelvic oncological surgery with various types of MS-VRAM flaps.

Author

Chen, Qiao, Dong, Ruijia, Zeng, Ang, Teng, Yue, Liu, Zhifei, Zhu, Lin, Long, Fei, Si, Loubin, Yu, Nanze, and Wang, Xiaojun

Abstract

Muscle-sparing vertical rectus abdominis myocutaneous (MS-VRAM) flaps are widely used in pelvic reconstruction. Aiming at optimal reconstructive outcomes, flap design and modification should be individualized to restore various kinds of defects. Summarize an empirical strategy about MS-VRAM selection for different pelvic and perineal reconstructions. Thirty patients who underwent total pelvic exenteration and pelvic reconstruction surgery from 2009 to 2017 were enrolled. The patients were divided into four groups according to the type of MS-VRAM-based flap used in the procedure: the modified long vertical flap (n = 10), the wrapping flap (n = 6), the de-epithelialized flap (n = 6), and the cork flap (n = 8). The follow-up period was 1 year after the surgery. Flap size, drainage volume, postoperative satisfaction, and complications were recorded, and postoperative photographs were collected. All of the patients achieved satisfying effect under the targeted reconstruction strategy. Of the four groups, the accurate cork flap finally acquires higher satisfaction, the shortest hospital stay, and the least total drainage volume. Meanwhile, the incidence of complications was not increased compared with the other groups. A new reconstructive strategy for pelvic reconstruction was established. Functional or non-functional reconstruction was accomplished by using various MS-VRAM flaps. Among them, the cork flap is the most economical flap to reconstruct pelvic floor defects with minimal tissue requirement and donor trauma. [ABSTRACT FROM AUTHOR]

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results