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Abstract: Large cell carcinoma of the lung with a rhabdoid phenotype is very rare. We present a 55-year-old man with multiple nodules in his lung. He had an emergency operation because of abundant hemoptysis. The microscopic appearance was a large cell carcinoma with a pure rhabdoid phenotype. There were no foci of any other carcinomatous components. Tumor cells had abundant eosinophilic cytoplasmic globules and eccentric nuclei and did not adhere to each other. Histochemically, these cells were periodic acid-Schiff–negative. Immunohistochemically, vimentin and neuron-specific enolase were positive. Epithelial membrane antigen was focally and weakly positive, p53 was positive in 60% of tumoral cells, and Ki-67 (MIB-1 labeling index) was 50%. The patient died of disseminated disease 2 months after the operation. [Copyright &y& Elsevier]

Advances in surgical techniques have indicated that video-assisted thoracoscopic pneumonectomy is a safe alternative to open pneumonectomy. However, indications for video-assisted thoracoscopic pneumonectomy are controversial. We describe two patients who underwent left pneumonectomy because of destroyed lungs and speculated about the tight adhesions, enlarged lymph nodes, enlarged bronchial vessels, and access incisions. Two patients were operated by two different approaches mainly; anterior and posterior, because of the degree of contralateral lung herniation. Both of them experienced a safe perioperative period. [ABSTRACT FROM AUTHOR]

We describe a 37-year-old female patient who had a major vehicle accident 17 years ago. A chest tube had been inserted through the left side of the chest to treat pneumothorax. She was readmitted to the hospital with dyspnea 17 years later. Her examinations, including fiberoptic bronchoscopy, revealed total atelectasis of the left lung with a blind-ending left main bronchus. Anastomosis of the left distal main bronchus to left main bronchus was performed. She had no complications and was discharged on postoperative day 8. Follow-up demonstrated a perfectly functioning left lung with nuclear and tomographic investigations performed on the first postoperative year. [Copyright &y& Elsevier]

An 8-year-old girl was evaluated for hemoptysis, 50 mL/day, which lasted for 3 days. Computed thoracic tomography detected a mass lesion in the right lower lobe. During rigid bronchoscopic examination, exanguinating hemoptysis occurred, and a Fogarty balloon catheter was placed in the right intermediate bronchus. Thoracotomy revealed a 2 × 2-cm mass in the right lower lobe. Common basal segmentectomy was performed. Pathological frozen-section analysis confirmed the diagnosis of perforated hydatid cyst. [Copyright &y& Elsevier]

Abstract: It is accepted that cardiopulmonary exercise testing is one of the most valuable parameters, especially peak oxygen uptake (VO2), for the evaluation of risk assessment in lung cancer surgery. It therefore represents an attractive way of identifying a patient at high risk for postoperative complications. However, many patients do not achieve the maximal or predictive level during an incremental exercise testing. The purpose of the current investigation was to study the value of the oxygen uptake efficiency slope (OUES), which shows exercise capacity during submaximal testing, in predicting postoperative mortality in patients with bronchogenic carcinoma scheduled for lung resection. Forty-nine patients with bronchogenic carcinoma participated in studies with exercise tests as a preoperative evaluation. The peak VO2 was calculated for each subject by averaging values obtained during the final 10s of exercise. The following equation was used to determine OUES: VO2/log10 VE. Peak VO2 without postoperative complication was 22.8±3.3ml/(kgmin), however, peak VO2 in patients with present complications was 19.1±4.2ml/(kgmin) (p =0.001). In addition, although the mean OUES in patients with present complications was 11.1±1.2, the mean OUES in the absent group was 13.3±2.1 (p <0.001). Although peak VO2 is useful in evaluating selected patients with bronchogenic carcinoma, OUES is also a beneficial parameter and should be calculated and recorded with peak VO2, a better predictor of poor surgical outcome than absolute values, and should be integrated into preoperative decision making. [Copyright &y& Elsevier]