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Your search keyword '"Stoksik, Magdalena"' showing total 1 results
Start Over Author "Stoksik, Magdalena" Publisher elsevier b.v.
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1. Tumor necrosis factor-alpha production-regulating activity of phthalimide derivatives in genetically modified murine melanoma cells B78H1

Author

Orzeszko, Andrzej, Lasek, Witold, Świtaj, Tomasz, Stoksik, Magdalena, and Kamińska, Beata

Subjects
*TUMOR necrosis factors, *CANCER cells, *IMIDES, *GENETIC transduction
Abstract

The effect of imides, monothioimides, trimellitimides, as well as 5′-deoxy-5′-phthaloylamino-derivatives of azidothymidine on tumor necrosis factor-alpha (TNF-α) production by genetically modified murine B78H1 melanoma cells transduced with the gene for human TNF-α (B78/TNF) was investigated. It was found that N-(adamant-1-yl)monothiophthalimide (1e) and N-(adamant-2-yl)-monothiophthalimide (1f) showed over 200% enhancing of TNF-α production while some of imides were inhibitors. [Copyright &y& Elsevier]

Published
2003
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