678 results on '"Singal A"'
Search Results
2. Systemic Therapies for Hepatocellular Carcinoma in India
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Jahagirdar, Vinay, Rama, Kaanthi, Habeeb, Mohammed F., Sharma, Mithun, Rao, Padaki N., Reddy, Duvvur N., Singal, Amit G., and Kulkarni, Anand V.
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- 2024
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3. The impact of stigma on quality of life and liver disease burden among patients with nonalcoholic fatty liver disease
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Younossi, Zobair M., AlQahtani, Saleh A., Funuyet-Salas, Jesús, Romero-Gómez, Manuel, Yilmaz, Yusuf, Keklikkiran, Caglayan, Alswat, Khalid, Yu, Ming-Lung, Liu, Chun-Jen, Fan, Jian-Gao, Zheng, Ming-Hua, Burra, Patrizia, Francque, Sven M., Castera, Laurent, Schattenberg, Jörn M., Newsome, Philip N., Allen, Alina M., El-Kassas, Mohamed, Treeprasertsuk, Sombat, Hameed, Saeed, Wai-Sun Wong, Vincent, Zelber-Sagi, Shira, Takahashi, Hirokazu, Kawaguchi, Takumi, Castellanos Fernández, Marlen I., Duseja, Ajay, Arrese, Marco, Rinella, Mary, Singal, Ashwani K., Gordon, Stuart C., Fuchs, Michael, Eskridge, Wayne, Alkhouri, Naim, Cusi, Kenneth, Loomba, Rohit, Ranagan, Jane, Kautz, Achim, Ong, Janus P., Kugelmas, Marcelo, Eguchi, Yuichiro, Diago, Moises, Gerber, Lynn, Lam, Brian, Fornaresio, Lisa, Nader, Fatema, Spearman, C. Wendy, Roberts, Stuart K., Chan, Wah-Kheong, Silva, Marcelo, Racila, Andrei, Golabi, Pegah, Ananchuensook, Prooksa, Henry, Linda, Stepanova, Maria, Carrieri, Patrizia, and Lazarus, Jeffrey V.
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- 2024
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4. Enhanced anti-malarial efficacy of mefloquine delivered via cationic liposome in a murine model of experimental cerebral malaria
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Raza, Mohsin, Bharti, Hina, Chauhan, Charu, Singal, Aakriti, Jha, Deepa, Ghosh, Prahlad C., and Nag, Alo
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- 2024
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5. Integration of SrFeO3-δ with reduced graphene oxide nanoribbon for symmetric/asymmetric capacitive charge storage
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Soni, Prakshi, Singal, Shobhita, Yadav, Ashish, and Sharma, Raj Kishore
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- 2024
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6. Expert opinion on bleeding risk from invasive procedures in cirrhosis
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Nezam H, Afdhal, Walter, Ageno, Marcello, Bianchini, Annabel, Blasi, Stephen H, Caldwell, Mark, Callaway, Andres, Cardenas, Sarwa, Darwish Murad, Andrea, De Gottardi, Lesley, De Pietri, Emmanuelle, De Raucourt, Alessandra, Dell'Era, Alban, Denys, Laure, Elkrief, Juan-Carlos, Garcia-Pagan, Guadalupe, Garcia-Tsao, Alexander, Gatt, Edoardo G, Giannini, Rita, Golfieri, Charles S, Greenberg, Virginia, Hernández-Gea, Mathis, Heydtmann, Nicolas M, Intagliata, Patrick S, Kamath, Will, Lester, Maria, Magnusson, James, Neuberger, Patrick G, Northup, G, O'Leary Jacqueline, Heather, Patton, Markus, Peck-Radosavljevic, Anjana, Pillai, Aurélie, Plessier, Pierre-Emmanuel, Rautou, Cristina, Ripoll, Lara N, Roberts, Ammar, Sarwar, Marco, Senzolo, Akash, Shukla, Paolo, Simioni, Douglas A, Simonetto, Ashwani K, Singal, Robin, Soto, Jonathan G, Stine, Elliot B, Tapper, Dominique, Thabut, Jecko, Thachil, Dana, Tomescu, Dhiraj, Tripathi, Emmanuel A, Tsochatzis, Erica, Villa, Dominique, Valla, Riescher-Tuczkiewicz, Alix, Caldwell, Stephen H., Kamath, Patrick S., Villa, Erica, and Rautou, Pierre-Emmanuel
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- 2024
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7. Characteristics and outcomes of immunotherapy-related liver injury in patients with hepatocellular carcinoma versus other advanced solid tumours
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Celsa, Ciro, Cabibbo, Giuseppe, Fulgenzi, Claudia A.M., Scheiner, Bernhard, D’Alessio, Antonio, Manfredi, Giulia F., Nishida, Naoshi, Ang, Celina, Marron, Thomas U., Saeed, Anwaar, Wietharn, Brooke, Pinter, Matthias, Cheon, Jaekyung, Huang, Yi-Hsiang, Lee, Pei-Chang, Phen, Samuel, Gampa, Anuhya, Pillai, Anjana, Vivaldi, Caterina, Salani, Francesca, Masi, Gianluca, Roehlen, Natascha, Thimme, Robert, Vogel, Arndt, Schönlein, Martin, von Felden, Johann, Schulze, Kornelius, Wege, Henning, Galle, Peter R., Kudo, Masatoshi, Rimassa, Lorenza, Singal, Amit G., El Tomb, Paul, Ulahannan, Susanna, Parisi, Alessandro, Chon, Hong Jae, Hsu, Wei-Fan, Stefanini, Bernardo, Verzoni, Elena, Giusti, Raffaele, Veccia, Antonello, Catino, Annamaria, Aprile, Giuseppe, Guglielmini, Pamela Francesca, Di Napoli, Marilena, Ermacora, Paola, Antonuzzo, Lorenzo, Rossi, Ernesto, Verderame, Francesco, Zustovich, Fable, Ficorella, Corrado, Di Pietro, Francesca Romana, Battelli, Nicola, Negrini, Giorgia, Grossi, Francesco, Bordonaro, Roberto, Pipitone, Stefania, Banzi, Maria, Ricciardi, Serena, Laera, Letizia, Russo, Antonio, De Giorgi, Ugo, Cavanna, Luigi, Sorarù, Mariella, Montesarchio, Vincenzo, Bordi, Paola, Brunetti, Leonardo, Pinto, Carmine, Bersanelli, Melissa, Cammà, Calogero, Cortellini, Alessio, and Pinato, David J.
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- 2024
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8. Association between public health policies on alcohol and worldwide cancer, liver disease and cardiovascular disease outcomes
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Díaz, Luis Antonio, Fuentes-López, Eduardo, Idalsoaga, Francisco, Ayares, Gustavo, Corsi, Oscar, Arnold, Jorge, Cannistra, Macarena, Vio, Danae, Márquez-Lomas, Andrea, Ramirez-Cadiz, Carolina, Medel, María Paz, Hernandez-Tejero, María, Ferreccio, Catterina, Lazo, Mariana, Roblero, Juan Pablo, Cotter, Thomas G., Kulkarni, Anand V., Kim, Won, Brahmania, Mayur, Louvet, Alexandre, Tapper, Elliot B., Dunn, Winston, Simonetto, Douglas, Shah, Vijay H., Kamath, Patrick S., Lazarus, Jeffrey V., Singal, Ashwani K., Bataller, Ramon, Arrese, Marco, and Arab, Juan Pablo
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- 2024
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9. Global survey of stigma among physicians and patients with nonalcoholic fatty liver disease
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Younossi, Zobair M., Alqahtani, Saleh A., Alswat, Khalid, Yilmaz, Yusuf, Keklikkiran, Caglayan, Funuyet-Salas, Jesús, Romero-Gómez, Manuel, Fan, Jian-Gao, Zheng, Ming-Hua, El-Kassas, Mohamed, Castera, Laurent, Liu, Chun-Jen, Wai-Sun Wong, Vincent, Zelber-Sagi, Shira, Allen, Alina M., Lam, Brian, Treeprasertsuk, Sombat, Hameed, Saeed, Takahashi, Hirokazu, Kawaguchi, Takumi, Schattenberg, Jörn M., Duseja, Ajay, Newsome, Phil N., Francque, Sven, Spearman, C. Wendy, Castellanos Fernández, Marlen I., Burra, Patrizia, Roberts, Stuart K., Chan, Wah-Kheong, Arrese, Marco, Silva, Marcelo, Rinella, Mary, Singal, Ashwani K., Gordon, Stuart, Fuchs, Michael, Alkhouri, Naim, Cusi, Kenneth, Loomba, Rohit, Ranagan, Jane, Eskridge, Wayne, Kautz, Achim, Ong, Janus P., Kugelmas, Marcelo, Eguchi, Yuichiro, Diago, Moises, Yu, Ming-Lung, Gerber, Lynn, Fornaresio, Lisa, Nader, Fatema, Henry, Linda, Racila, Andrei, Golabi, Pegah, Stepanova, Maria, Carrieri, Patrizia, and Lazarus, Jeffrey V.
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- 2024
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10. A meta-analysis and real-world cohort study on the sex-related differences in efficacy and safety of immunotherapy for hepatocellular carcinoma
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Balcar, Lorenz, Scheiner, Bernhard, Fulgenzi, Claudia Angela Maria, D’Alessio, Antonio, Pomej, Katharina, Roig, Marta Bofill, Meyer, Elias Laurin, Che, Jaekyung, Nishida, Naoshi, Lee, Pei-Chang, Wu, Linda, Ang, Celina, Krall, Anja, Saeed, Anwaar, Stefanini, Bernardo, Cammarota, Antonella, Pressiani, Tiziana, Abugabal, Yehia I., Chamseddine, Shadi, Wietharn, Brooke, Parisi, Alessandro, Huang, Yi-Hsiang, Phen, Samuel, Vivaldi, Caterina, Salani, Francesca, Masi, Gianluca, Bettinger, Dominik, Vogel, Arndt, von Felden, Johann, Schulze, Kornelius, Silletta, Marianna, Trauner, Michael, Samson, Adel, Wege, Henning, Piscaglia, Fabio, Galle, Peter R., Stauber, Rudolf, Kudo, Masatoshi, Singal, Amit G., Itani, Aleena, Ulahannan, Susanna V., Parikh, Neehar D., Cortellini, Alessio, Kaseb, Ahmed, Rimassa, Lorenza, Chon, Hong Jae, Pinato, David J., and Pinter, Matthias
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- 2024
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11. Liver Cancer in 2021: Global Burden of Disease Study
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Tan, En Ying, Danpanichkul, Pojsakorn, Yong, Jie Ning, Yu, Zhenning, Tan, Darren Jun Hao, Lim, Wen Hui, Koh, Benjamin, Lim, Ryan Yan Zhe, Tham, Ethan Kai Jun, Mitra, Kartik, Morishita, Asahiro, Hsu, Yao-Chun, Yang, Ju Dong, Takahashi, Hirokazu, Zheng, Ming-Hua, Nakajima, Atsushi, Ng, Cheng Han, Wijarnpreecha, Karn, Muthiah, Mark D., Singal, Amit G., and Huang, Daniel Q.
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- 2024
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12. Impact of pre-transplant immune checkpoint inhibitor use on post-transplant outcomes in HCC: A systematic review and individual patient data meta-analysis
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Rezaee-Zavareh, Mohammad Saeid, Yeo, Yee Hui, Wang, Tielong, Guo, Zhiyong, Tabrizian, Parissa, Ward, Stephen C., Barakat, Fatma, Hassanein, Tarek I., Dave, Shravan, Ajmera, Veeral, Bhoori, Sherrie, Mazzaferro, Vincenzo, Chascsa, David M.H., Liu, Margaret C., Aby, Elizabeth S., Lake, John R., Sogbe, Miguel, Sangro, Bruno, Abdelrahim, Maen, Esmail, Abdullah, Schmiderer, Andreas, Chouik, Yasmina, Rudolph, Mark, Sohal, Davendra, Giudicelli, Heloise, Allaire, Manon, Akce, Mehmet, Guadagno, Jessica, Tow, Clara Y., Massoumi, Hatef, De Simone, Paolo, Kang, Elise, Gartrell, Robyn D., Martinez, Mercedes, Paz-Fumagalli, Ricardo, Toskich, Beau B., Tran, Nguyen H., Solino, Gabriela Azevedo, Poltronieri Pacheco, Dra Mariana, Kalman, Richard S., Agopian, Vatche G., Mehta, Neil, Parikh, Neehar D., Singal, Amit G., and Yang, Ju Dong
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- 2024
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13. Optimal sizing of an integrated renewable energy system and effective utilization of surplus energy in electric vehicle charging
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Saini, Vishal and Singal, S.K.
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- 2023
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14. Racial and ethnic inequities in psychiatric inpatient building and unit assignment
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Michaels, Timothy I., Thomas, Elsa, Flaxer, Joseph M., Singal, Sonali, Hanna, Lauren, Van Meter, Anna, Tang, Sunny X., Kane, John M., and Saito, Ema
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- 2023
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15. Isolated choroid plexus cysts and health and developmental outcomes in childhood and adolescence – A systematic review
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Singal, Kusum, Adamczyk, Krzysztof, Hurt, Lisa, Woolner, Andrea, and Paranjothy, Shantini
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- 2023
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16. MELD 3.0 adequately predicts mortality and renal replacement therapy requirements in patients with alcohol-associated hepatitis
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Díaz, Luis Antonio, Fuentes-López, Eduardo, Ayares, Gustavo, Idalsoaga, Francisco, Arnold, Jorge, Valverde, María Ayala, Perez, Diego, Gómez, Jaime, Escarate, Rodrigo, Villalón, Alejandro, Ramírez, Carolina A., Hernandez-Tejero, Maria, Zhang, Wei, Qian, Steve, Simonetto, Douglas A., Ahn, Joseph C., Buryska, Seth, Dunn, Winston, Mehta, Heer, Agrawal, Rohit, Cabezas, Joaquín, García-Carrera, Inés, Cuyàs, Berta, Poca, Maria, Soriano, German, Sarin, Shiv K., Maiwall, Rakhi, Jalal, Prasun K., Abdulsada, Saba, Higuera-de-la-Tijera, Fátima, Kulkarni, Anand V., Rao, P. Nagaraja, Salazar, Patricia Guerra, Skladaný, Lubomir, Bystrianska, Natália, Clemente-Sanchez, Ana, Villaseca-Gómez, Clara, Haider, Tehseen, Chacko, Kristina R., Romero, Gustavo A., Pollarsky, Florencia D., Restrepo, Juan Carlos, Castro-Sanchez, Susana, Toro, Luis G., Yaquich, Pamela, Mendizabal, Manuel, Garrido, Maria Laura, Marciano, Sebastián, Dirchwolf, Melisa, Vargas, Victor, Jiménez, César, Louvet, Alexandre, García-Tsao, Guadalupe, Roblero, Juan Pablo, Abraldes, Juan G., Shah, Vijay H., Kamath, Patrick S., Arrese, Marco, Singal, Ashwani K., Bataller, Ramon, and Arab, Juan Pablo
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- 2023
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17. Structural engineering and carbon enrichment in V2CTx MXene: An approach for enhanced supercapacitive charge storage
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Yadav, Ashish, Singal, Shobhita, Soni, Prakshi, Singh, Gurmeet, and Sharma, Raj Kishore
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- 2023
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18. Efficacy and safety of immune checkpoint inhibitor rechallenge in individuals with hepatocellular carcinoma
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Scheiner, Bernhard, Roessler, Daniel, Phen, Samuel, Lim, Mir, Pomej, Katharina, Pressiani, Tiziana, Cammarota, Antonella, Fründt, Thorben W., von Felden, Johann, Schulze, Kornelius, Himmelsbach, Vera, Finkelmeier, Fabian, Deibel, Ansgar, Siebenhüner, Alexander R., Shmanko, Kateryna, Radu, Pompilia, Schwacha-Eipper, Birgit, Ebert, Matthias P., Teufel, Andreas, Djanani, Angela, Hucke, Florian, Balcar, Lorenz, Philipp, Alexander B., Hsiehchen, David, Venerito, Marino, Sinner, Friedrich, Trauner, Michael, D'Alessio, Antonio, Fulgenzi, Claudia A.M., Pinato, David J., Peck-Radosavljevic, Markus, Dufour, Jean-François, Weinmann, Arndt, Kremer, Andreas E., Singal, Amit G., De Toni, Enrico N., Rimassa, Lorenza, and Pinter, Matthias
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- 2023
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19. Blood-based biomarkers for hepatocellular carcinoma screening: Approaching the end of the ultrasound era?
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Parikh, Neehar D., Tayob, Nabihah, and Singal, Amit G.
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- 2023
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20. Fuzzy-MAC: An FIS based MAC protocol for a multi-constrained traffic in wireless body area networks
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Ray, Kaushik, Pal, Vipin, Singal, Gaurav, and Moulik, Soumen
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- 2022
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21. Liver Biopsy in Patients With Alcohol-Associated Liver Disease With Acute-on-Chronic Liver Failure
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Jophlin, Loretta and Singal, Ashwani K.
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- 2022
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22. Rational HCC screening approaches for patients with NAFLD
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Singal, Amit G. and El-Serag, Hashem B.
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- 2021
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23. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic : a comprehensive demographic analysis for the Global Burden of Disease Study 2021
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Schumacher, A. E., Kyu, H. H., Antony, C. M., Aravkin, A. Y., Azhar, G. S., Bisignano, C., Burkart, K., Cercy, K. M., Chung, E., Coberly, K., Comfort, H., Cousin, E., Culbreth, G. T., Cunningham, M., Weaver, N. D., Degenhardt, L., Deitesfeld, L., Dirac, M. A., Estep, K., Feigin, V. L., Flaxman, A. D., Flor, L. S., Force, L. M., Fuller, J. E., Gakidou, E., Hay, S. I., Ikuta, K. S., Jones, D. P., Kassebaum, N. J., Kassel, M. B., Keller, C., Kinzel, K. E., Krohn, K. J., Lozano, R., May, E. A., McKowen, A. W., McLaughlin, S. A., Mehlman, M. L., Mestrovic, T., Mokdad, A. H., Mosser, J. F., Mougin, V., Naghavi, M., Nesbit, O. D., Novotney, A., Ozten, Y., Pease, S. A., Pigott, D. M., Reiner, R. C., Robinson-Oden, H. E., Shaw, D. H., Slepak, E. L. N., Sorensen, R. J. D., Verghese, N. A., Vollset, S., Vongpradith, A., Vos, T., Wang, D., Watson, S., Weaver, M. R., Wells, K. M., Wilson, S., Wool, E. E., Zheng, P., Lim, S. S., Murray, C. J. L., Boyko, E. J., Chahine, Y., Kalani, R., Krishnamoorthy, V., Khalil, I. A., Minja, N. W., Morrison, S. D., Nafukho, F. M., Olivas-Martinez, A., Orellana, E., Tram, K., Aali, A., Rahnavard, N., Ahmadzade, A., Mohammad-Pour, S., Morovatdar, N., Pourali, G., Zafari, N., Abbafati, C., Cattaruzza, M. S., Abbas, J., Phillips, M. R., Abbasgholizadeh, R., Emamverdi, M., Friedman, J., Abbasi, M. A., Daneshvar, S., Dashti, M., Ghasemzadeh, A., Mirza-Aghazadeh-Attari, M., Doshmangir, L., Ghafourifard, M., Lotfi, M., Hosseini, M., Jadidi-Niaragh, F., Kalankesh, L. R., Karimi, S., Mohammad-Alizadeh-Charandabi, S., Khalafi, M., Mirghafourvand, M., Mirinezhad, S., Heris, R. M., Mousavi, S., Kafil, H. S., Abbasian, M., Momenzadeh, K., Santos, F. C. D., Carr, S., Chi, G., Elgendy, I. Y., Feroze, A. H., Kempen, J. H., Kubeisy, C. M., Li, Z., Rohloff, P., Liu, X., Natto, Z. S., Olanipekun, T. O., Pigeolet, M., Pradhan, P. M. S., Zweck, E., Sharfaei, S., Sheikh, A., Abtahi, D., Salimi, S., Shakeri, A., Tajbakhsh, A., Aghamiri, S., Ahmadzade, M., Hashemi, M. B., Ajami, M., Asgary, S., Ghasemi, M., Hassanian-Moghaddam, H., Kolahi, A., Nikoobar, A., Heidari-Foroozan, M., Montazeri, F., Nejadghaderi, S., Rahmani, S., Ziaeefar, P., Hesami, H., Zahir, M., Jahankhani, K., Rasouli-Saravani, A., Jahanmehr, N., Kashani, H. K., Nasiri, M., Raee, P., Rezaee, M., Safi, S., Shool, S., Tabatabai, S., ElHafeez, S. A., Tantawi, M. E., Elmeligy, O. A. A., Ghazy, R. M., Talaat, I. M., Abdelmasseh, M., Sanabria, J., Abd-Elsalam, S., Abdelwahab, A., Abdollahi, M., Abolhassani, H., Rezaei, N., Saghazadeh, A., Ala, M., Noroozi, N., Bahri, R. A., Khatami, F., Ayyoubzadeh, S., Azadnajafabad, S., Keykhaei, M., Momtazmanesh, S., Mousavi, P., Behnoush, A., Farrokhpour, H., Karimi, H., Khalaji, A., Khanmohammadi, S., Mayeli, M., Mohammadi, S., Eskandarieh, S., Sahraian, M., Fahimi, S., Malekzadeh, R., Mansouri, V., Sepanlou, S. G., Ghassemi, F., Haddadi, M., Kazemian, S., Khadembashiri, M., Khamesipour, F., Khavandegar, A., Khormali, M., Salamati, P., Kompani, F., Larijani, B., Mirdamadi, N., Seyedi, S., Malazy, O. T., Mahmoudi, E., Rashedi, S., Rad, E. M., Mansournia, M., Nasab, E. M., Mohammadshahi, M., Mostafavi, H., SeyedAlinaghi, S., Shafie, M., Shahbandi, A., Vahdani, A. M., Sharifan, A., Shirkoohi, R., Sohrabi, H., Tavangar, S., Heidari-Soureshjani, R., Abdoun, M., Abdullahi, A., Awotidebe, A. W., Borodo, S. B., Gadanya, M. A., Ladan, M., Ali, M. U., Tyrovolas, S., Abdurehman, A. M., Debele, A. T., Getachew, T., Gudeta, M. D., Misgana, T., Sertsu, A., Abebe, M., Ayele, G. M., Afework, A., Lerango, T. L., Tebeje, T. M., Sibhat, M. M., Tesfaye, S. H., Abedi, A., Gholamrezanezhad, A., Salehi, S., Athari, S., Hanifi, N., Abegaz, T. M., Kifle, Z. D., Zuñiga, R. A. A., Abhilash, E. S., Abiodun, O. O., Aboagye, R. G., Amu, H., Ayanore, M. A., Dowou, R. K., Immurana, M., Klu, D., Orish, V. N., Carrero, J. J., Cederroth, C. R., Deuba, K., Laflamme, L., Fereshtehnejad, S., Kauppila, J. H., Abouzid, M., Abreu, L. G., Malta, D. C., Prates, E. J. S., Nascimento, B. R., Abrha, W. A., Weldemariam, A. H., Girmay, A., Abrigo, M. R. M., Rumeileh, S. A., Abu-Rmeileh, N. M., Aburuz, S., Ahmed, L. A., Alam, Z., Elbarazi, I., Grivna, M., Nauman, J., Khan, G., Khan, M. A., Zaki, N., Ahmad, M. M., Abu-Zaid, A., Temsah, R. M. H., Zand, R., Acuna, J. M., Gautam, P., Chowdhury, R., Adair, T., Jiang, H., Babu, A. S., Borschmann, R., Meretoja, A., Wijeratne, T., Addo, I. Y., Okeke, S. R., Dai, Z., Xu, X., Huda, M., Mitchell, P. B., Peden, A. E., Resnikoff, S., Sharma, S., Si, Y., Sitas, F., Ye, P., Adebayo, O. M., Aladelusi, T. O., Salami, A. A., Ilesanmi, O. S., Owolabi, M. O., Adegboye, O. A., Adekanmbi, V., AlBataineh, M. T., Almahmeed, W., Aden, B., Adepoju, A. V., Adetunji, C. O., Adeyeoluwa, T. E., Oyeyemi, I. T., Oyeyemi, O. T., Udoakang, A. J., Adeyomoye, O. I., Anuoluwa, I. A., Bello, O. O., Oluwafemi, Y. D., Ekundayo, T. C., Idowu, O. O., Oluwatunase, G. O., Afolabi, A. A., Ekholuenetale, M., Fagbamigbe, A. F., Olufadewa, I. I., Ibitoye, S. E., Okekunle, A. P., Adha, R., Adikusuma, W., Adibi, A., Chen, M., Hossain, M., Rasali, D. P., Pashaei, A., Adnani, Q. E. S., Postma, M. J., Adra, S., Barqawi, H. J., Dash, N. R., Halwani, R., Maghazachi, A. A., Saber-Ayad, M. M., Sharif-Askari, N. S., Ahmad, F., Saddik, B., Saleh, M. A., Alzoubi, K. H., Omar, H. A., Arumugam, A., Bustanji, Y., Elemam, N. M., Faris, M. E. M., Karim, A., Qaisar, R., Semreen, M. H., Soliman, S. S. M., Altirkawi, K. A., Afraz, A., Ilaghi, M., Nematollahi, M., Afyouni, S., Amindarolzarbi, A., Zandieh, G. G. Z., Columbus, A., Kamireddy, A., Shafaat, O., Kazemi, F., Vervoort, D., Zhang, H., Jamshidi, E., Afzal, S., Agasthi, P., Agodi, A., Barchitta, M., D'Amico, E., Maugeri, A., Veroux, M., Biondi, A., Isola, G., Vacante, M., Falzone, L., Libra, M., Agyemang-Duah, W., Nikpoor, A., Ahinkorah, B. O., Demant, D., Ahmad, A., Mustafa, G., Pathan, A. R., Tabish, M., Ahmad, D., Bagheri, N., Burns, R. A., Cherbuin, N., Ahmad, T., Ahmadi, K., Saxena, S., Beaney, T., Palladino, R., Rawaf, S., Mossialos, E., Rawaf, D. L., Ahmed, A., Siddig, E. E., Ahmed, H., Ahmed, M. B., Shiferaw, D., Ashemo, M. Y., Gerema, U., Getachew, M. E., Bayileyegn, N. S., Mohamed, A. I., Eshetie, T. C., Tiruye, T. Y., Ahmed, S., Ali, H., Bodunrin, A. O., Tumurkhuu, M., Tung, K., Ubah, C. S., Aruleba, R. T., Aji, B., Ajumobi, O., Akalu, G. T., Beyene, H. B., Deribe, K., Ijo, D., Kassaw, N. A., Akara, E., Akinosoglou, K., Akkala, S., Asaad, M., Hassan, A. M., Bleyer, A., Akyirem, S., Bell, M. L., Song, Y., Etaee, F., Goldust, M., Li, W., Pawar, S., Hamad, H. A., Sathian, B., Hasan, S. A., Homsi, A. A., Almidani, O., Göbölös, L., Qadire, M. A., AL-Ahdal, T. M. A., Chen, S., Moazen, B., Alalalmeh, S. O., Hegazi, O. E., Shahwan, M. J., Shamsi, M. A., Zyoud, S. 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R., Salaroli, L. B., Salem, M. Z. Y., Samara, K. A., Samuel, V. P., Sanadgol, N., Sanganyado, E., Sanjeev, R. K., Santri, I. N., Saravi, B., Sarmiento-Suárez, R., Sathish, T., Sleet, D. A., Sattin, D., Saulam, J., Sayeed, M., Talukder, A., Saylan, M., Schuermans, A., Eynde, J. V. D., Schwendicke, F., Šekerija, M., Selvaraj, S., Sengupta, P., Senthilkumaran, S., Sethi, Y., Shah, P. A., Shahid, I., Shaikh, M. A., Sham, S., Shamshad, H., Shamshirgaran, M., Shariff, M., Sharifi-Rad, J., Sharma, R., Shastry, R. P., Shavandi, A., Shey, R., Shayan, A., Shehabeldine, A. M. E., Shen, J., Shibuya, K., Shigematsu, M., Shin, J., Shiri, R., Shivarov, V., Shrestha, S., Shuja, K., Shuval, K., Silva, L. M. R., Simões, J. P., Singh, B., Sivakumar, S., Skryabina, A. A., Starodubova, A. V., Solmi, M., Solomon, Y., Tefera, Y. M., Soyiri, I., Soyiri, I. N., Sreeramareddy, C. T., Starnes, J. R., Varavikova, E., Sreeramareddy, C., Starodubov, V. I., Stroumpoulis, K., Suleman, M., Abdulkader, R. S., Sultana, A., Sun, J., Swain, C. K., Sykes, B. L., Szarpak, L., Szeto, M. D., Damavandi, P. T., Tabatabaeizadeh, S., Tabb, K. M., Taborda-Barata, L. M., Tabuchi, T., Tadesse, B. T., Abkenar, Y. T., Udoh, A., Soodejani, M. T., Taiba, J., Tang, H., Tat, N. Y., Teimoori, M., Thangaraju, P., Thankappan, K. R., Thomas, N., Thum, C. C., Tichopad, A., Ticoalu, J. H. V., Tohidast, S., Tran, N. M., Trico, D., Truong, V. T., Truyen, T. T., Ulhaq, I., Umeokonkwo, C. D., Umesh, A., Vaithinathan, A. G., Varga, O., Vasankari, T. J., Venugopal, D., Verma, P., Villanueva, G. I., Villeneuve, P. J., Vlassov, V., Vo, B., Volovat, S. R., Waheed, Y., Wamai, R. G., Wang, F., Wang, S., Zhang, C., Weerakoon, K. G., Wickramasinghe, N. D., Wen, Y., Woolf, A. D., Wu, D., Xiao, H., Yaghoubi, S., Yano, Y., Yonemoto, N., Yigit, A., Yigit, V., Younis, M. Z., Younis, M., Zadey, S., Zadnik, V., Zahid, M. N., Zaman, B. A., Zaman, S., Zamora, N., Zanghì, A., Zare, I., Zeng, Y., Zhai, C., Zhang, Y., Zhao, H., Zhao, Y., Zhou, J., and Zhu, B.
- Abstract
Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, ant
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- 2024
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24. Cost of hospitalization for care of children with epidermolysis bullosa in the US.
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Desai, Amar D., Singal, Amit, Behbahani, Sara, Soliman, Yssra, and Hawryluk, Elena B.
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- 2024
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25. Hazard identification and consumer safety characterization for trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd)
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Singal, Madhuri, Nuber, David, Rusch, George M., Engelhardt, Jeffery A., and Mukhi, Sandeep
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- 2020
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26. Granulocyte colony-stimulating factor for alcoholic hepatitis: A systematic review and meta-analysis of randomised controlled trials
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Marot, Astrid, Singal, Ashwani K., Moreno, Christophe, and Deltenre, Pierre
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- 2020
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27. Corridor segmentation for automatic robot navigation in indoor environment using edge devices
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Gupta, Surbhi, R, Sangeeta, Mishra, Ravi Shankar, Singal, Gaurav, Badal, Tapas, and Garg, Deepak
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- 2020
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28. Estimation of Software Development Effort: A Differential Evolution Approach
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Singal, Prerna, Kumari, A Charan, and Sharma, Prabha
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- 2020
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29. Minimally invasive spine surgeries for treatment of thoracolumbar fractures of spine: A systematic review
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Pannu, Chaitanya Dev, Farooque, Kamran, Sharma, Vijay, and Singal, Deepika
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- 2019
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30. Current trials and novel therapeutic targets for alcoholic hepatitis
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Singal, Ashwani K. and Shah, Vijay H.
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- 2019
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31. Modes of Death in Patients with Cardiogenic Shock in the Cardiac Intensive Care Unit: A Report from the Critical Care Cardiology Trials Network.
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BERG, DAVID D., SINGAL, SACHIT, PALAZZOLO, MICHAEL, BAIRD-ZARS, VIVIAN M., BOFARRAG, FADEL, BOHULA, ERIN A., CHAUDHRY, SUNIT-PREET, DODSON, MARK W., HILLERSON, DUSTIN, LAWLER, PATRICK R., LIU, SHUANGBO, O'BRIEN, CONNOR G., PISANI, BARBARA A., RACHARLA, LEKHA, ROSWELL, ROBERT O., SHAH, KEVIN S., SOLOMON, MICHAEL A., SRIDHARAN, LAKSHMI, THOMPSON, ANDREA D., and DIEPEN, SEAN VAN
- Abstract
There are limited data on how patients with cardiogenic shock (CS) die. The Critical Care Cardiology Trials Network is a research network of cardiac intensive care units coordinated by the Thrombolysis In Myocardial Infarction (TIMI) Study Group (Boston, MA). Using standardized definitions, site investigators classified direct modes of in-hospital death for CS admissions (October 2021 to September 2022). Mutually exclusive categories included 4 modes of cardiovascular death and 4 modes of noncardiovascular death. Subgroups defined by CS type, preceding cardiac arrest (CA), use of temporary mechanical circulatory support (tMCS), and transition to comfort measures were evaluated. Among 1068 CS cases, 337 (31.6%) died during the index hospitalization. Overall, the mode of death was cardiovascular in 82.2%. Persistent CS was the dominant specific mode of death (66.5%), followed by arrhythmia (12.8%), anoxic brain injury (6.2%), and respiratory failure (4.5%). Patients with preceding CA were more likely to die from anoxic brain injury (17.1% vs 0.9%; P <.001) or arrhythmia (21.6% vs 8.4%; P <.001). Patients managed with tMCS were more likely to die from persistent shock (P <.01), both cardiogenic (73.5% vs 62.0%) and noncardiogenic (6.1% vs 2.9%). Most deaths in CS are related to direct cardiovascular causes, particularly persistent CS. However, there is important heterogeneity across subgroups defined by preceding CA and the use of tMCS. [ABSTRACT FROM AUTHOR]
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- 2024
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32. Grand Rounds: Alcoholic Hepatitis
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Singal, Ashwani K., Louvet, Alexandre, Shah, Vijay H., and Kamath, Patrick S.
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- 2018
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33. Multi-constraints link stable multicast routing protocol in MANETs
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Singal, Gaurav, Laxmi, Vijay, Gaur, M.S., Todi, Swati, Rao, Vijay, Tripathi, Meenakshi, and Kushwaha, Riti
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- 2017
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34. Endovascular management of traumatic pseudoaneurysm: Short & long term outcomes
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Mohan, Bishav, Singal, Shekhar, Bawa, Akshdeep Singh, Mahindra, Pankaj, and Yamin, Mohammad
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- 2017
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35. KAMRA presbyopic inlay refractive outcomes: a Canadian perspective.
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Darian-Smith, Erica, Gouvea, Larissa, Gendler, Shai, Alshaker, Sara, Din, Nizar, Weill, Yishay, Skouras, Nick, Rabinovitch, Theodore, Singal, Neera, Chan, Clara C., and Rootman, David S.
- Abstract
Copyright of Canadian Journal of Ophthalmology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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36. Cholestatic jaundice in a fitness enthusiast
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Das, Kangkana, Singal, Dinesh Kumar, and Hussain, Amer
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- 2024
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37. Cutaneous tuberculosis. Part II: Complications, diagnostic workup, histopathologic features, and treatment.
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Kaul, Subuhi, Jakhar, Deepak, Mehta, Shilpa, and Singal, Archana
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Despite the availability of effective treatment regimens for cutaneous tuberculosis, challenges to disease control result from delayed diagnosis, infection with multidrug-resistant mycobacterial strains, and coinfection with HIV. Delayed diagnosis can be mitigated when dermatologists are sensitized to the clinical signs and symptoms of infection and by the incorporation of appropriate diagnostic tests. All cases of cutaneous tuberculosis should be confirmed with histopathology and culture with or without molecular testing. In each case, a thorough evaluation for systemic involvement is necessary. Mycobacteria may not be isolated from cutaneous tuberculosis lesions and therefore, a trial of antituberculosis treatment may be required to confirm the diagnosis. The second article in this 2-part continuing medical education series describes the sequelae, histopathology, and treatment of tuberculosis. [ABSTRACT FROM AUTHOR]
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- 2023
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38. Cutaneous tuberculosis. Part I: Pathogenesis, classification, and clinical features.
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Kaul, Subuhi, Kaur, Ishmeet, Mehta, Shilpa, and Singal, Archana
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Tuberculosis is an ancient disease that continues to affect an estimated 10 million people per year and is responsible for 1.4 million deaths per year. Additionally, the HIV epidemic and multidrug resistance present challenges to disease control. Cutaneous tuberculosis is an uncommon, often indolent, manifestation of mycobacterial infection that has a varied presentation. Its diagnosis is challenging, as lesions mimic other, more common conditions and microbiological confirmation is often not possible. Cutaneous tuberculosis can be broadly categorized into multibacillary and paucibacillary forms. Approximately one-third of skin tuberculosis is associated with systemic involvement. By recognizing cutaneous tuberculosis early, dermatologists can play an important role in disease control. The first article in this 2-part continuing medical education series describes the latest epidemiology, microbiology, and pathogenesis of tuberculosis. Furthermore, we review the classification, clinical manifestations, common clinical differentials, and systemic involvement that occur in cutaneous tuberculosis. [ABSTRACT FROM AUTHOR]
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- 2023
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39. Comovement revisited
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Chen, Honghui, Singal, Vijay, and Whitelaw, Robert F.
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- 2016
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40. Reply to: “Correction for length bias reduces the mortality benefit from hepatocellular carcinoma surveillance”
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Singal, Amit G., Marrero, Jorge, and Parikh, Neehar D.
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- 2023
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41. SAT-129 - Sub-optimal global public health policies and strategies to combat hepatocellular carcinoma
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Diaz, Luis Antonio, Norero, Blanca, Corsi, Oscar, Ayares, Gustavo, Idalsoaga, Francisco, García, Sergio, Vázquez, Valeria, Lacalle, Lucas, Lazo, Mariana, Ferreccio, Catterina, Mendizabal, Manuel, Piñero, Federico, Martinez, Edmundo, Ijeoma, Ifeorah, Louvet, Alexandre, Piano, Salvatore, Cortez-Pinto, Helena, Wong, Vincent Wai-Sun, Kulkarni, Anand, Cotter, Thomas, Brahmania, Mayur, roblero, Juan Pablo, Dirchwolf, Melisa, Pollarsky, Florencia, George, Jacob, Stauber, Rudolf E., Francque, Sven, Guerra, Patricia, Oliveira, Claudia, Araujo, Roberta, Álvares-da-Silva, Mario, Blaise, Nkegoum, Abraldes, Juan G, Zheng, Ming-Hua, Toro, Luis, Restrepo, Juan Carlos, Ramirez, Wagner, Grgurević, Ivica, Infante, Mirtha, Mbendi, Charles, Carrera, Enrique, El Kassas, Mohamed, Mahmoud, Abdelmajeed, Tesfaye, Yonas Gedamu, Tadesse, Sewale Anagaw, Akalu, Tiruwork Fekadu, Desalegn, Hailemichael, Allaire, Manon, Patrizia, Carrieri, Schattenberg, Jörn, Aguyire, Joan, Micah, Eileen Akonobea, Tachi, Kenneth, Maldonado Cardona, Katherine Emilia, Sanchez, Abel, Sánchez, Marco, Björnsson, Einar S., Iavarone, Massimo, Okamoto, Ryuichi, Some, Fatuma, Hellani, Mohammad Fadel, Prado Gonzalez, Veronica Enith, Chávez-Tapia, Norberto Carlos, Méndez-Sánchez, Nahum, Mabote Mucumbi, Sheila Constância, Ugiagbe, Rose Ashinedu, Akande, Kolawole, Nwoko, Chinenye, Ezenkwa, Uchenna Simon, Okoye, Ifeoma Joy, Hamid, Saeed Sadiq, Quezada, Julissa Lombardo, Girala, Marcos, Padilla, P. Martin, Diaz-Ferrer, Javier, Tagle, Martin, Kukla, Michał, Odeghe, Emuobor, wemimo, Rasheed mumini, Reis, Daniela, Mozgovoi, Sergei, Ismail, Mona, Koller, Tomas, Spearman, Wendy, Elhassan, Moawia, Stal, Per, Pazi, Swaleh, Ocanit, Anthony, Masson, Steven, Dunn, Winston, Kamath, Patrick S., Singal, Ashwani, Debes, Jose, Reig, María, Loomba, Rohit, Bataller, Ramon, Lazarus, Jeffrey, Arrese, Marco, and Arab, Juan Pablo
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- 2023
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42. Evidence and choice: The BCLC vision for tailoring clinical decision-making
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Reig, Maria, Forner, Alejandro, Rimola, Jordi, Ferrer-Fàbrega, Joana, Burrel, Marta, Garcia-Criado, Ángeles, Kelley, Robin K., Galle, Peter R., Mazzaferro, Vincenzo, Salem, Riad, Sangro, Bruno, Singal, Amit G., Vogel, Arndt, Fuster, Josep, Ayuso, Carmen, and Bruix, Jordi
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- 2024
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43. HCC surveillance improves early detection, curative treatment receipt, and survival in patients with cirrhosis: A meta-analysis
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Amit G. Singal, Emily Zhang, Manasa Narasimman, Nicole E. Rich, Akbar K. Waljee, Yujin Hoshida, Ju Dong Yang, Maria Reig, Giuseppe Cabibbo, Pierre Nahon, Neehar D. Parikh, Jorge A. Marrero, Singal A.G., Zhang E., Narasimman M., Rich N.E., Waljee A.K., Hoshida Y., Yang J.D., Reig M., Cabibbo G., Nahon P., Parikh N.D., and Marrero J.A.
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liver cancer ,Settore MED/12 - Gastroenterologia ,Hepatology ,Screening ,cirrhosi ,Unresectable hepatocel-lular carcinoma - Abstract
Background & Aims: There is controversy regarding the overall value of hepatocellular carcinoma (HCC) surveillance in patients with cirrhosis given the lack of data from randomized-controlled trials. To address this issue, we conducted a systematic review and meta-analysis of cohort studies evaluating the benefits and harms of HCC surveillance in patients with cirrhosis. Methods: We performed a search of the Medline and EMBASE databases and national meeting abstracts from January 2014 through July 2020 for studies reporting early-stage HCC detection, curative treatment receipt, or overall survival, stratified by HCC surveillance status, among patients with cirrhosis. Pooled risk ratios (RRs) and hazard ratios, according to HCC surveillance status, were calculated for each outcome using the DerSimonian and Laird method for random effects models. Results: We identified 59 studies including 145,396 patients with HCC, which was detected by surveillance in 41,052 (28.2%) cases. HCC surveillance was associated with improved early-stage detection (RR 1.86, 95% CI 1.73–1.98; I2 = 82%), curative treatment receipt (RR 1.83, 95% CI 1.69–1.97; I2 = 75%), and overall survival (hazard ratio 0.67, 95% CI 0.61–0.72; I2 = 78%) after adjusting for lead-time bias; however, there was notable heterogeneity in all pooled estimates. Four studies examined surveillance-related physical harms due to false positive or indeterminate surveillance results, but no studies examined potential financial or psychological harms. The proportion of patients experiencing surveillance-related physical harms ranged from 8.8% to 27.5% across studies, although most harms were mild in severity. Conclusion: HCC surveillance is associated with improved early detection, curative treatment receipt, and survival in patients with cirrhosis, although there was heterogeneity in pooled estimates. Available data suggest HCC surveillance is of high value in patients with cirrhosis, although continued rigorous studies evaluating benefits and harms are still needed. Lay summary: There has been ongoing debate about the overall value of hepatocellular carcinoma (HCC) screening in patients with cirrhosis given the lack of data from randomized-controlled trials. In a systematic review of contemporary cohort studies, we found that HCC screening is associated with improved early detection, curative treatment receipt, and survival in patients with cirrhosis, although there were fewer data quantifying potential screening-related harms. Available data suggest HCC screening is of high value in patients with cirrhosis, although continued studies evaluating benefits and harms are still needed.
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- 2022
44. The quest for precision oncology with immune checkpoint inhibitors for hepatocellular carcinoma
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Giuseppe Cabibbo, Amit G. Singal, Cabibbo G., and Singal A.G.
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Settore MED/12 - Gastroenterologia ,Carcinoma, Hepatocellular ,Hepatology ,business.industry ,Immune checkpoint inhibitors ,Immune Checkpoint Inhibitor ,Liver Neoplasms ,medicine.disease ,liver cancer ,Precision oncology ,Hepatocellular carcinoma ,medicine ,Cancer research ,Humans ,Precision Medicine ,Liver cancer ,business ,Immune Checkpoint Inhibitors ,prognosi ,Human - Abstract
NA
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- 2022
45. Prevention of Hepatocellular Carcinoma (HCC). White Paper of the Texas Collaborative Center for Hepatocellular Cancer (TeCH) Multi-stakeholder Conference.
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El-Serag, Hashem B., Ward, John W., Asrani, Sumeet K., Singal, Amit G., Rich, Nicole, Thrift, Aaron P., Deshpande, Salil, Turner, Barbara J., Kaseb, Ahmed O., Harrison, Ariel C., Fortune, Brett E., and Kanwal, Fasiha
- Abstract
Texas has the highest age-adjusted incidence rate of hepatocellular carcinoma (HCC) in the United States. The Cancer Prevention and Research Institute of Texas has funded the Texas Collaborative Center for Hepatocellular Cancer (TeCH) to facilitate HCC research, education, and advocacy activities with the overall goal of reducing HCC mortality in Texas through coordination, collaboration, and advocacy. On September 17, 2022, TeCH co-sponsored a multi-stakeholder conference on HCC with the Baker Institute Center for Health and Biosciences. This conference was attended by HCC researchers, policy makers, payers, members from pharmaceutical industry and patient advocacy groups in and outside of Texas. This report summarizes the results of the conference. The goal of this meeting was to identify different strategies for preventing HCC and evaluate their readiness for implementation. We call for a statewide (1) viral hepatitis elimination program; (2) program to increase nonalcoholic steatohepatitis and obesity awareness; (3) research program to develop health care models that integrate alcohol associated liver disease treatment and treatment for alcohol use disorder; and (4) demonstration projects to evaluate the effectiveness of identifying and linking patient with advanced fibrosis and cirrhosis to clinical care. [ABSTRACT FROM AUTHOR]
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- 2023
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46. Breakthroughs in Hepatocellular Carcinoma Therapies.
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Singal, Amit G., Kudo, Masatoshi, and Bruix, Jordi
- Abstract
Several breakthroughs in hepatocellular carcinoma (HCC) therapy across tumor stages provide hope to improve its dismal prognosis. Although surgical and local ablative therapies have few significant changes in technique, an improved understanding of tumor biology has facilitated increase numbers of patients who are now eligible to undergo curative-intent procedures. Most notably, acceptable post-transplant outcomes can be achieved in well selected patients whose tumors are downstaged into Milan Criteria. Adjuvant therapy in patients at high risk of recurrence also significantly improves recurrence-free survival after resection or ablation. For patients with liver-localized disease who are not eligible for curative-intent procedures, transarterial chemoembolization (TACE) was historically the treatment modality of choice, regardless of tumor burden; however, there is now increased recognition of patients who are "TACE unsuitable" and may be better treated with systemic therapy. The greatest evolution in HCC treatment options has occurred with systemic therapy, where several new agents are now available in the first- and second-line setting, including immune checkpoint inhibitor combinations. Objective responses are observed in approximately 30% of patients and median survival is approaching 2 years. The availability of immune checkpoint inhibitors has renewed interest in combination therapies for earlier tumor stages, with several phase III trials ongoing. Considering increasing complexities of HCC care, requiring decisions between therapies delivered by different providers, multidisciplinary care is critical and is associated with improved clinical outcomes. In this review, we detail major breakthroughs in HCC therapy, how these breakthroughs can be applied in clinical practice, and remaining areas in need of further research. [ABSTRACT FROM AUTHOR]
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- 2023
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47. International Liver Cancer Association (ILCA) white paper on hepatocellular carcinoma risk stratification and surveillance.
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Singal, Amit G., Sanduzzi-Zamparelli, Marco, Nahon, Pierre, Ronot, Maxime, Hoshida, Yujin, Rich, Nicole, Reig, Maria, Vilgrain, Valerie, Marrero, Jorge, Llovet, Josep M., Parikh, Neehar D., and Villanueva, Augusto
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- *
LIVER cancer , *HEPATOCELLULAR carcinoma , *CANCER-related mortality , *HEPATITIS B , *MEDICAL screening - Abstract
Major research efforts in liver cancer have been devoted to increasing the efficacy and effectiveness of surveillance for hepatocellular carcinoma (HCC). As with other cancers, surveillance programmes aim to detect tumours at an early stage, facilitate curative-intent treatment, and reduce cancer-related mortality. HCC surveillance is supported by a large randomised-controlled trial in patients with chronic HBV infection and several cohort studies in cirrhosis; however, effectiveness in clinical practice is limited by several barriers, including inadequate risk stratification, underuse of surveillance, and suboptimal accuracy of screening tests. There are several proposed strategies to address these limitations, including risk stratification algorithms and biomarkers to better identity at-risk individuals, interventions to increase surveillance, and emerging imaging- and blood-based surveillance tests with improved sensitivity and specificity for early HCC detection. Beyond clinical validation, data are needed to establish clinical utility, i.e. increased early tumour detection and reduced HCC-related mortality. If successful, these data could facilitate a precision screening paradigm in which surveillance strategies are tailored to individual HCC risk to maximise overall surveillance value. However, practical and logistical considerations must be considered when designing and implementing these validation efforts. To address these issues, ILCA (the International Liver Cancer Association) adjourned a single topic workshop on HCC risk stratification and surveillance in June 2022. Herein, we present a white paper on these topics, including the status of the field, ongoing research efforts, and barriers to the translation of emerging strategies. [ABSTRACT FROM AUTHOR]
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- 2023
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48. Comparative evaluation of four Descemet membrane endothelial keratoplasty graft preparation techniques.
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Din, Nizar, Mimouni, Michael, Slomovic, Jacqueline, Aldrees, Sultan, Trinh, Tanya, Cohen, Eyal, Gouvea, Larissa, Alshaker, Sara, Chan, Clara C., Chew, Hall F., Singal, Neera, Rootman, David S., and Slomovic, Allan R.
- Abstract
Copyright of Canadian Journal of Ophthalmology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
49. Systematically optimized biocompatible isotretinoin-loaded solid lipid nanoparticles (SLNs) for topical treatment of acne
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Raza, Kaisar, Singh, Bhupinder, Singal, Parteek, Wadhwa, Sheetu, and Katare, Om Prakash
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- 2013
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50. Increasing the visibility of Asian American, Native Hawaiian, and Pacific Islanders in substance use research: A call to action
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Saraiya, Tanya C., Hien, Denise Nguyen, Singal, Sonali, and Hahm, Hyeouk Chris
- Published
- 2024
- Full Text
- View/download PDF
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