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Purpose: This study aimed to evaluate the anti-inflammatory effect of oral dexamethasone 4 mg in a single dose preemptively administered to reduce pain, swelling, and trismus following mandibular third molar surgeries.Methods: A split-mouth randomized clinical trial was performed including 22 participants undergoing surgical removal of bilateral and symmetrically positioned third molars. A total of 44 teeth were allocated by simple randomization to either the test or nonintervention/control side. Oral dexamethasone 4 mg was administered on the test side an hour before the surgery. All of the participants were unaware of the medication studied, and only 1 surgeon, blinded to the medication intake, performed all of the procedures. Anti-inflammatory effect was evaluated using the clinical parameters of mouth opening, swelling, and rescue analgesic medication intake to control pain. The statistical analysis was blinded to the allocation groups, and a significance value P < .05 was adopted for all the tests.Results: Dexamethasone reduced the mean of rescue analgesic medication intake by 5 times (P = .002). Facial swelling was lower on the test side by 72h postsurgery in comparison with the control side (P = .036). No significant difference in mouth opening was found between the groups.Conclusions: Preemptive use of oral dexamethasone 4 mg proved to be effective in controlling pain and reducing the need for rescue medication and had a beneficial effect in reducing swelling during a short postoperative period. [ABSTRACT FROM AUTHOR]

Highlights • Ultrasound scanner can make dental digital impressions under porcine gingiva. • Ultrasound scanner crowns presented mean marginal gap of 117.59 ± 55.86 μm. • Ultrasound scanner crowns presented lower marginal fit compared to optical ones. • Ultrasound crowns presented internal fit similar to at least one optical scanner. Abstract Objective This in vitro study aimed to evaluate marginal and internal fit of single crowns produced from high-frequency ultrasound based digital impressions of teeth prepared with finish lines covered by porcine gingiva, in comparison with those obtained by optical scanners with uncovered finish lines. Methods Ten human teeth were prepared and forty zirconia crowns were fabricated from STL-datasets obtained from four dental scanners (n = 10): extraoral CS2 (Straumann), intraoral Lava COS (3M), intraoral Trios (3Shape) and extraoral ultrasound scanner. The accuracy of the crowns was compared evaluating marginal and internal fit by means of the replica technique with measurements in four areas; P1: occlusal surface; P2: transition between occlusal and axial surfaces; P3: middle of axial wall; and P4: marginal gap. Restoration margins were classified according to their mismatch as regular, underextended or overextended. Kruskal–Wallis one-way ANOVA and Mann–Whitney U test were used to evaluate the differences between groups at p < 0.05. Results The median value of marginal gap (P4) for Ultrasound (113.87 μm) differed statistically from that of CS2 (39.74 μm), Lava COS (41.98 μm) and Trios (42.07 μm). There were no statistical differences between ultrasound and Lava COS for internal misfit (P1–P3), however there were statistical differences when compared with the other two scanners (Trios and CS2) at P1 and P2. Significance The ultrasound scanner was able to make digital impressions of prepared teeth through porcine gingiva (P4), however with less accuracy of fit than that of conventional optical scanners without coverage of the finish lines. Where no gingiva was available (P1–P3), the ultrasound accuracy of fit was similar to that of at least one optical scanner (Lava COS). [ABSTRACT FROM AUTHOR]