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Your search keyword '"Philips, Joseph B."' showing total 3 results
Start Over Author "Philips, Joseph B." Publisher elsevier b.v.
3 results on '"Philips, Joseph B."'

1. The effectiveness of risk-based intrapartum chemoprophylaxis for the prevention or early-onset neonatal group B streptococcal disease

Author

Lin, Feng Ying C., Brenner, Ruth A., Johnson, Yvette R., Azimi, Parvin H., Philips, Joseph B., III, Regan, Joan A., Clark, Penny, Weisman, Leonard E., Rhoads, George G., King, Fanhui, and Clemens, John D.

Subjects
Streptococcal infections -- Prevention, Pregnant women -- Care and treatment, Antibiotics -- Usage, Health
Abstract

Giving antibiotics to pregnant women who have risk factors for group B streptococcal infection can prevent the infection in over 80%, according to a study of 316 women. It is best to give the antibiotics at least two hours before delivery for greatest effectiveness.

Published
2001

2. Low-dose aspirin therapy to prevent preeclampsia

Author

Hauth, John C., Goldenberg, Robert L., Parker, Richard, Jr., Philips, Joseph B., III, Copper, Rachel L., DuBard, Mary B., and Cutter, Gary R.

Subjects
Aspirin -- Health aspects, Preeclampsia -- Prevention, Health
Abstract

Treatment with a low dosage of aspirin each day may be an effective method for preventing or reducing the severity of preeclampsia in pregnant women. Preeclampsia is the development of hypertension during pregnancy with increased levels of protein in the urine and fluid collection. Among 604 pregnant women under 28 years old in the 24th week of pregnancy, 302 took 60 milligrams of aspirin per day and 302 took a placebo, or an inactive substance, until the time of delivery. Five women (2%) treated with aspirin developed preeclampsia, compared with 17 women (6%) who took a placebo. Only one women in the aspirin group developed severe preeclampsia, compared with six women in the placebo group. Preeclampsia and other pregnancy-associated hypertensive disorders cause a significant number of fetal, newborn and maternal deaths.

Published
1993

3. The Role of Patent Ductus Arteriosus Ligation in Bronchopulmonary Dysplasia: Reexamining a Randomized Controlled Trial.

Author

Clyman, Ronald, Cassady, George, Kirklin, James K., Collins, Monica, and Philips, Joseph B.

Abstract

Objective: To reexamine data from a randomized controlled trial of prophylactic ductus ligation to determine whether ligation contributes directly to the development of bronchopulmonary dysplasia (BPD) in extremely low birth weight infants. Study Design: The control group underwent ligation only if they had development of a symptomatic patent ductus arteriosus (PDA). The Prophylactic Ligation group underwent ligation within 24 hours of birth regardless of the presence or absence of symptoms of a PDA. We hypothesized that the incidence of BPD would be higher in the prophylactic ligation group because more ligations were performed than in the control group. Results: Prophylactic ligation significantly increased the incidence of BPD (defined as a supplemental oxygen requirement at 36 weeks postmenstrual age) and the incidence of mechanical ventilation at 36 weeks. The groups were statistically similar in gestation, sex, race, fluid administration, intraventricular hemorrhage, pulmonary air leaks, and survival to 36 weeks. The lower incidence of BPD in the control group occurred despite the fact that the incidence of necrotizing enterocolitis (a known risk factor for BPD) was significantly elevated in the control group. Only infants who had previously undergone a PDA ligation had development of BPD in the control group. Conclusion: Prophylactic ligation, while eliminating the PDA, increases the risk for BPD. [Copyright &y& Elsevier]

Published
2009
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