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Start Over Author "Philip, Vinitha" Publisher elsevier b.v.
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2. Human immunodeficiency virus infection and chronic myeloid leukemia

Author

Patel, Moosa, Philip, Vinitha, Fazel, Fatima, Lakha, Atul, Vorog, Alexander, Ali, Nazeer, Karstaedt, Alan, and Pather, Sugeshni

Subjects
*HIV infections, *CHRONIC myeloid leukemia, *ANTIRETROVIRAL agents, *DRUG interactions, *PROTEIN-tyrosine kinase inhibitors, *IMMUNODEFICIENCY
Abstract

Abstract: CML (chronic myeloid leukaemia) in association with HIV (human immunodeficiency virus) infection (HIV–CML) is rarely described and is likely to be coincidental. The natural history and behaviour of HIV–CML is different, being more atypical and aggressive. Both conditions, and their respective treatments may cause myelosuppression. Concurrent treatment with cART (combination antiretroviral therapy) and the tyrosine kinase inhibitors (TKI''s) can result in appropriate control of CML and HIV infection, as well as long term survival. However, drug interactions between ARV''s and TKI''s may require adjustment of treatment. [Copyright &y& Elsevier]

Published
2012
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