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Start Over Author "Offenhauser, Nina" Publisher elsevier b.v.
1 results on '"Offenhauser, Nina"'

1. Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics

Author

Offenhauser, Nina, Soppo, Blanche Ekalle, Rossi, Paola, Pozzi, Benedetta, Scita, Giorgio, Heberlein, Ulrike, Fiore, Pier Paolo Di, Disanza, Andrea, Guamieri, Douglas, Betsholtz, Christer, Frassoni, Carolina, Amadeo, Alida, Tocchetti, Arianna, D'Angelo, Egidio, Regondl, Maria Cristina, Castelletti, Daniela, and Mapelli, Lisa

Subjects
Alcohol -- Analysis, Alcohol, Denatured -- Analysis, Actin -- Analysis, Nitrogen compounds -- Analysis, Biological sciences
Abstract

The evidence for mechanisms linking actin dynamics to behavioral responses to ethanol is provided from study report about Eps8, which regulates acute ethanol sensitivity and ethanol consumption in mice. From the result it is concluded that Eps8 is required in the N-methyl-D-aspartate receptor-signaling pathway leading to activation of cofilin and actin-filament turnover.

Published
2006

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