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Start Over Author "Nicoletti R" Publisher elsevier b.v.
43 results on '"Nicoletti R"'

1. P129 - Real-world data analysis of treatment outcomes for patients with metastatic hormone-sensitive prostate cancer: development of a survival prediction model. Results from the European network of excellence for big data in prostate cancer (PIONEER)

Author

Gómez Rivas, J., Nicoletti, R., Golozar, A., Ayman, H., Steinbeißer, C., Ibañez, L., De Meulder, B., Axelsson, S.E., Snijder, R., Feng, Q., Bjartell, A., Cornford, P., Willemse, P., Prinsen, P., Murtola, T.J., and N´dow, J.

Published
2023
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2. P096 - Real-world data analysis of clinical characteristics in metastatic hormone-sensitive prostate cancer: Are patients from RCTs the same from real life? Data from the European network of excellence for big data in prostate cancer (PIONEER).

Author

Gómez Rivas, J., Nicoletti, R., Golozar, A., Steinbeißer, C., De Meulder, B., Snijder, R., Ibañez, L., Axelsson, S.E., Ayman, H., Feng, Q., Murtola, T.J., Bjartell, A., Cornford, P., Willemse, P., Prinsen, P., and N´dow, J.

Published
2023
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3. A0643 - Development of a predictive model for death amongst patients with Metastatic Hormone Sensitive Prostate Cancer (mHSPC) treated with one of the approved treatment plans, on characteristics present at admission using Big data: Preliminary results from the European network of excellence for big data in prostate cancer (PIONEER)

Author

Nicoletti, R., Gomez Rivas, J., Ibánez, L., Steinbeisse, C., de Meulder, B., Ayman, H., Golozar, A., Snijder, R., Van Hemelrijck, M., Beyer, K., Willemse, P-P., Murtola, T., Roobol, M.J., Moreno-Sierra, J., Campi, R., Gacci, M., Mottet, N., Merseburger, A., Cornford, P., and Ndow, J.

Subjects
*BIG data, *PROSTATE cancer, *PREDICTION models, *METASTASIS, *HORMONES
Published
2024
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4. Do my hands prime your hands? The hand-to-response correspondence effect

Author

Scerrati, Elisa, Iani, C., Lugli, L., Nicoletti, R., Rubichi, S., Scerrati E. (ORCID:0000-0002-4042-6140), Scerrati, Elisa, Iani, C., Lugli, L., Nicoletti, R., Rubichi, S., and Scerrati E. (ORCID:0000-0002-4042-6140)

Abstract

Previous research has shown an effect of handle-response correspondence on key-press responses when participants judged the upright or inverted orientation of photographed one-handled graspable objects. In three experiments, we explored whether this effect still holds for symmetric graspable objects that are usually grasped by two hands (i.e. two-handled objects; e.g. shears). In Experiments 1 and 2, participants were required to perform a between-hand response in order to categorize cooking or amusement objects appearing as grasped from either an allocentric (Experiment 1) or an egocentric perspective (Experiment 2). In Experiment 3, they were required to perform a within-hand response to categorize the same stimuli appearing as grasped from an egocentric perspective. Across all three experiments, results showed that categorization was more difficult when the objects were displayed as grasped on the opposite side than the response rather than on the same side. We discuss the implications of these results for theories of action potentiation and spatial coding and suggest that different mechanisms may be recruited depending on the required action (i.e. response mode).

Published
2020

6. SC289 - Translating the results of the keynote-564 trial to clinical practice: characteristics and outcomes of patients with clear-cell non-metastatic renal cell carcinoma (RCC) who may potentially benefit from adjuvant pembrolizumab after surgery at a referral academic centre

Author

Mariotti, A., Pecoraro, A., Stracci, D., Gallo, M.L., Marzocco, A., Valeria, L., Mazzola, L., Dibilio, E., Polverino, P., Nicoletti, R., Re, M. Lo, Conte, F.L., Alberti, A., Sessa, F., Sebastianelli, A., Gacci, M., Serni, S., and Campi, R.

Published
2022
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8. SC286 - Assessing the intraoperative morbidity of kidney cancer surgery for organ-confined (CT1-T2N0M0) renal masses at a high-volume centre: the value of the eau intraoperative adverse incident classification for standardized reporting

Author

Stracci, D., Gallo, M.L., Pecoraro, A., Mariotti, A., Marzocco, A., Livio, V., Mazzola, L., Dibilio, E., Polverino, P., Nicoletti, R., Lo Re, M., Conte, F.L., Alberti, A., Sessa, F., Giancane, S., Vignolini, G., Gacci, M., Serni, S., and Campi, R.

Published
2022
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11. A0014 - Trifecta and Pentafecta after robot-assisted laparoscopic prostatectomy with bladder neck sparing and maximal urethral length preservation in patients with large prostates (>100cc).

Author

Alberti, A., Nicoletti, R., Dibilio, E., Resta, G.R., Makrides, P., Caneschi, C., Ciaralli, E., Cifarelli, A., D'Amico, A., Paganelli, D., Saladino, M., Mazzola, L., Lo Re, M., Polverino, P., Rivetti, A., Facchiano, D., Spatafora, P., Sebastianelli, A., Campi, R., and Serni, S.

Subjects
*SURGICAL robots, *PROSTATECTOMY, *BLADDER, *PROSTATE
Published
2024
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13. A1101 - Perioperative and functional outcomes after kidney transplantation from uncontrolled donors after circulatory death vs. expanded-criteria donors after brain death vs. standard-criteria donors: Toward an evidence-based refinement of allocation strategies

Author

Campi, R., Pecoraro, A., Sessa, F., Barzaghi, P., Rivetti, A., Nicoletti, R., Gallo, M.L., Corti, F., Morselli, S., Spatafora, P., Gacci, M., Giancane, S., Sebastianelli, A., Cirami, L., Peris, A., Vignolini, G., Serni, S., and Li Marzi, V.

Published
2022
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16. SC308 - Assessing the intra- and postoperative morbidity of kidney cancer surgery for organ-confined (cT1-T2N0M0) renal masses according to the eau quality criteria for standardized reporting: a prospective single-centre study

Author

Serni, S., Pecoraro, A., Rivetti, A., Sessa, F., Barzaghi, P., Corti, F., Caneschi, C., Santalmasi, C., Paganelli, D., Basilico, V., Morselli, S., Nicoletti, R., Giancane, S., Spatafora, P., Gacci, M., Li Marzi, V., Sebastianelli, A., Vignolini, G., and Campi, R.

Published
2021
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18. 1796P Real-world analysis of metastatic hormone-sensitive prostate cancer: Are randomized clinical trials more trustworthy? Insights from PIONEER, the European network of excellence for big data in prostate cancer.

Author

Gómez Rivas, J., Nicoletti, R., Golozar, A., Steinbeißer, C., Ibañez, L., De Meulder, B., Evans Axelsson, S., Snijder, R., Bjartell, A., Cornford, P., Willemse, P-P., Prinsen, P., Murtola, T., and N'Dow, J.

Subjects
*PROSTATE cancer, *TRUST, *BIG data, *CLINICAL trials, *METASTASIS
Published
2023
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21. A0641 - Analysis of clinical characteristics in metastatic hormone-sensitive prostate cancer. A comparative study of patients from cal trials to patients from real life using Big Data.

Author

Ibanez Vazquez, L., Gómez Rivas, J., Nicoletti, R., Golozar, A., Steinbeißer, C., De Meulder, B., Snijder, R., Axelsson, S.E., Ayman, H., Feng, Q., Bjartell, A., Cornford, P., Murtola, T.J., Willemse, P., Moreno Sierra, J., and N'dow, J.

Subjects
*BIG data, *PROSTATE cancer, *COMPARATIVE studies, *METASTASIS
Published
2024
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33. A0608 - Which is the optimal multimodal management of pN1 patients with PSA persistence after radical prostatectomy and extended nodal dissection? Results of a large, multi-institutional database.

Author

Scuderi, S.L.A., Marra, G., Olivier, J., Stabile, A., Mazzone, E., Afferi, L., Mattei, A., Malkiewicz, B., Gallina, S., Antonelli, A., Zattoni, F., Van Den Bergh, R., Rajwa, P., Shariat, S.F., Cathelineau, X., Nicoletti, R., Campi, R., Ahmed, M., Karnes, R.J., and Heidegger, I.

Subjects
*RADICAL prostatectomy, *DATABASES, *PROSTATE-specific antigen, *DISSECTION
Published
2024
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34. A0609 - Adjuvant or early salvage radiotherapy in node positive prostate cancer patients: Development of a novel risk score to identify the optimal candidate for early intensification approaches based on a large, multi-institutional series.

Author

Barletta, F.M., Marra, G., Olivier, J., Grogg, J.B., Hermanns, T., Afferi, L., Mattei, A., Malkiewicz, B., Antonelli, A., Zattoni, F., Dal Moro, F., Van Den Bergh, R., Rajwa, P., Shariat, S.F., Cathelineau, X., Nicoletti, R., Campi, R., Ahmed, M., Karnes, R.J., and Heidegger, I.

Subjects
*DISEASE risk factors, *PROSTATE cancer patients, *CARCINOGENESIS, *RADIOTHERAPY
Published
2024
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35. Selecting patients for resection after primary chemotherapy for non-metastatic pancreatic adenocarcinoma.

Author

Reni, M., Zanon, S., Balzano, G., Nobile, S., Pircher, C. C., Chiaravalli, M., Passoni, P., Arcidiacono, P. G., Nicoletti, R., Crippa, S., Slim, N., Doglioni, C., Falconi, M., and Gianni, L.

Subjects
*ADENOCARCINOMA, *CANCER chemotherapy, *PACLITAXEL, *DISEASE progression, *MULTIVARIATE analysis, *KARNOFSKY Performance Status
Abstract

Background: Patients with borderline (BL) or locally advanced (LA) pancreatic adenocarcinoma are usually treated with primary chemotherapy (CT), followed by resection when feasible. Scanty data are available about the criteria to candidate patients to resection after CT. Patients and methods: Between 2002 and 2016 overall 223 patients diagnosed with BL or LA pancreatic adenocarcinoma were primarily treated with Gemcitabine combination (4-drugs or nab-paclitaxel-gemcitabine) for 3-6 months followed by surgery and/or chemoradiation. Resection was carried out when radical resection could be predicted by imaging studies and intraoperative findings. The prognostic value of both pre-treatment factors and treatment response was retrospectively evaluated, searching for criteria that could improve the selection of patients for surgery. Results: Median survival (MS) for the whole population was 18.3 months. Surgical resection was carried out in 61 patients; MS in resected patients was significantly longer (30.0 months) as compared with 162 non-resected patients (16.5 months) (P<0.00001). According to response criteria, 48% had a radiological partial response, 47% a stable disease and 5% a disease progression); CA19.9 response (reduction>50%) was obtained in 77.8% of patients. Among resected patients, neither pretreatment factors, including BL/LA distinction, nor radiological response, were able to prognosticate survival differences. Survival of resected patients having no CA19.9 response was significantly lower as compared with responders (MS 15.0 versus 31.5 months, P=0.04), and was similar to non-responders patients that did not undergo resection (MS 10.9 months, P=0.25). Multivariate analysis carried out on the overall population, showed that Karnofsky performance status, T3-T4 status, resection and CA19.9 response were independent prognostic factors, while radiological response, BL/LA distinction and baseline CA19.9 had not significant influence on survival. Conclusions: CA19.9 response may allow a better selection of patients who will benefit from resection after primary CT for BL or LA pancreatic adenocarcinoma. [ABSTRACT FROM AUTHOR]

Published
2017
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37. A1271 - Is it really safe to omit staging chest computed tomography in patients with incidentally diagnosed cT1a renal masses who are candidates for surgery? An audit from a high-volume referral academic centre.

Author

Pecoraro, A., Mariotti, A., Mariottini, R., Mazzola, L., Orsini, A., Livio, V., Firenzuoli, N., Nicoletti, R., Spatafora, P., Facchiano, D., Sessa, F., Sebastianelli, A., Gacci, M., Vignolini, G., Li Marzi, V., Serni, S., and Campi, R.

Subjects
*DIAGNOSIS, *SURGERY, *PATIENTS
Published
2023
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38. A1269 - Potential impact of the renewed TNM Staging System proposed by the EAU guidelines on renal cell carcinoma on decision-making for patients with localized renal masses: Insights from a referral kidney cancer centre.

Author

Campi, R., Pecoraro, A., Mariotti, A., Mariottini, R., Mazzola, L., Orsini, A., Resta, G.R., Dibilio, E., Alberti, A., Stracci, D., Firenzuoli, N., Nicoletti, R., Spatafora, P., Facchiano, D., Sessa, F., Sebastianelli, A., Vignolini, G., Gacci, M., Li Marzi, V., and Serni, S.

Subjects
*RENAL cell carcinoma, *RENAL cancer, *DECISION making
Published
2023
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39. A1029 - Renal function trajectories after enucleative robot-assisted partial nephrectomy for non-metastatic renal masses in patients with two kidneys and preserved baseline renal function: Does warm ischemia still have a role?

Author

Pecoraro, A., Mariotti, A., Mariottini, R., Mazzola, L., Orsini, A., Livio, V., Firenzuoli, N., Nicoletti, R., Gallo, M.L., Spatafora, P., Facchiano, D., Sessa, F., Sebastianelli, A., Gacci, M., Vignolini, G., Li Marzi, V., Serni, S., and Campi, R.

Subjects
*KIDNEY physiology, *SURGICAL robots, *NEPHRECTOMY, *KIDNEYS, *ISCHEMIA
Published
2023
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40. Gemcitabine versus cisplatin, epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: a randomised controlled multicentre phase III trial.

Author

Reni M, Cordio S, Milandri C, Passoni P, Bonetto E, Oliani C, Luppi G, Nicoletti R, Galli L, Bordonaro R, Passardi A, Zerbi A, Balzano G, Aldrighetti L, Staudacher C, Villa E, and Di Carlo V

Abstract

BACKGROUND: Patients with advanced pancreatic adenocarcinoma have a poor response, progression-free survival, and overall survival with standard treatment. We aimed to assess whether a four-drug regimen could improve 4 month progression-free survival compared with gemcitabine alone. METHODS: In a randomised multicentre phase III trial, 52 patients were randomly assigned to 40 mg/m2 cisplatin and 40 mg/m2 epirubicin both given on day 1, 600 mg/m2 gemcitabine given intravenously over 1 h on days 1 and 8, and 200 mg/m2 fluorouracil a day given by continuous infusion on days 1-28 of a 4-week cycle (PEFG regimen), and 47 were assigned to 1000 mg/m2 gemcitabine given intravenously over 30 min once a week for 7 of 8 consecutive weeks in cycle 1 and for 3 of 4 weeks thereafter. The primary endpoint was 4-month progression-free survival. Secondary endpoints were overall survival, objective response, safety, and quality of life. Analyses were by intention to treat. FINDINGS: 51 patients assigned PEFG and 46 assigned gemcitabine alone had disease progression. 49 patients in the PEFG group and 46 in the gemcitabine group died from progressive disease. More patients allocated PEFG than gemcitabine alone were alive without progressive disease at 4 months (60% [95% CI 46-72] vs 28% [17-42]; hazard ratio [HR] 0.46 [0.26-0.79]). 1-year overall survival in the PEFG group was 38.5% (25.3-51.7) and in the gemcitabine group was 21.3% (9.6-33.0; HR 0.68 [0.42-1.09]). More patients assigned PEFG showed disease response than did those assigned gemcitabine (38.5% [25.3-51.7] vs 8.5% [0.5-16.5]; odds ratio 6.60 [2.11-20.60], p=0.0008). More patients in the PEFG group had grade 3-4 neutropenia and thrombocytopenia than in the gemcitabine group (p<0.0001). INTERPRETATION: The PEFG regimen could be considered for treatment of advanced pancreatic adenocarcinoma. [ABSTRACT FROM AUTHOR]

Published
2005
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41. Static behavior of plain journal bearings with textured journal - Experimental analysis.

Author

Filgueira Filho, I.C.M., Bottene, A.C., Silva, E.J., and Nicoletti, R.

Subjects
*JOURNAL bearings, *LUBRICATED friction, *SURFACE texture, *KNOWLEDGE gap theory, *PLAINS, *ELASTOHYDRODYNAMIC lubrication
Abstract

The search for more efficient machines leads to the reduction of friction in the lubricated contacts. One of the ways of achieving this goal is by texturing the surface of the contact. Much has been learned from textures imposed to the bearing casing or pads (static part of the lubricated contact), but there is still a gap in the knowledge of textured journals (moving part of the contact) and their resultant effects on the performance of the bearing. In this work, we present the experimental analysis of a journal bearing whose journal is textured with four different patterns: chevron, saw tooth, oblong dimple, and aligned dimple. Such patterns were imposed to the surface of the journal by the pattern grinding technology. We analyze the resultant eccentricity, attitude angle, and the driving torque of the journal for different operating conditions of the bearing (different Sommerfeld numbers). The obtained results show that the chevron pattern and the oblong dimple pattern present the biggest effects on the studied parameters. Such effect can be either positive or negative depending on the direction of motion of the pattern in the bearing (for unsymmetrical patterns). The aligned dimple texture did not present any significant effect on the bearing performance in comparison to the untextured case. [Display omitted] • Textures on the journal can result in higher bearing load carrying capacity. • Effects depend on the direction of motion of the unsymmetrical patterns. • Chevron texture has significant effects due to fluid pumping caused by its geometry. • Dimples increase load capacity without affecting attitude angle and driving torque. • The saw tooth texture presents smaller effects on the parameters. [ABSTRACT FROM AUTHOR]

Published
2021
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