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Your search keyword '"Michel, M.S."' showing total 101 results
Start Over Author "Michel, M.S." Publisher elsevier b.v.
101 results on '"Michel, M.S."'

3. Radical cystectomy under continuous antiplatelet therapy with acetylsalicylic acid.

Author

Wessels, F., Kriegmair, M.C., Oehme, A., Rassweiler-Seyfried, M.C., Erben, P., Oberneder, R., Kriegmair, M., Ritter, M., Michel, M.S., and Honeck, P.

Subjects
CYSTECTOMY, ASPIRIN, BLOOD loss estimation, BLADDER cancer
Abstract

Aim of this study was to analyse the perioperative outcome of patients undergoing radical cystectomy under continuous antiplatelet therapy with acetylsalicylic acid. Using prospectively maintained databases of two departments of urology, we identified 461 consecutive patients who underwent radical cystectomy for bladder cancer (2011–2017). Patients were divided into three groups: 1) on-going antiplatelet therapy with acetylsalicylic acid (n = 50), 2) discontinuing antiplatelet therapy (n = 65) and 3) no antiplatelet therapy (n = 346). Perioperative outcome was compared between the three groups using ANOVA, likelihood ratio or Kruskal Wallis test with post-hoc testing. Uni- and multivariate analyses were performed to identify predictor for perioperative complications and transfusion. Group 1 showed an average estimated blood loss of 732 ± 424, group 2 752 ± 488 and group 3 810 ± 544 ml (p = 0.51). There was no significant difference in transfusion rate (44% in group 1, 45% and 39% in groups 2 and 3, p = 0.63). Severe complications occurred in 26%, 15% and 15% in groups 1–3 (p = 0.19). Ischemic complications were more often observed in group 1 (n = 4, 8%) and 2 (n = 5, 8%) than group 3 (n = 7, 2%), p = 0.02. 90-day readmission (n = 99, 22%) and mortality rate (n = 10, 2.2%) were low and did not show any significant differences between the groups. In uni- and multivariate analysis ongoing therapy with acetylsalicylic acid was no independent risk factor for transfusion or severe complications. Perioperative continuation of therapy with acetylsalicylic acid in radical cystectomy is safe with no difference in intraoperative blood loss, transfusion rate, complications or mortality. [ABSTRACT FROM AUTHOR]

Published
2019
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47. A0656 - A randomised controlled adaptive design phase III trial comparing a peritoneal flap versus no flap for lymphocele prevention after robotic-assisted radical prostatectomy with pelvic lymph node dissection: The PELYCAN study.

Author

Neuberger, M., Kowalweski, K-F., Simon, V., Wessels, F., Siegel, F., Worst, T.S., Westhoff, N., Von Hardenberg, J., Kriegmair, M.C., Michel, M.S., Honeck, P., and Nuhn, P.

Subjects
*CLINICAL trials, *LYMPHADENECTOMY, *RADICAL prostatectomy, *LYMPHOCELE
Published
2023
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