Search

Your search keyword '"MacIntosh, A."' showing total 353 results
Start Over Author "MacIntosh, A." Publisher elsevier b.v.
353 results on '"MacIntosh, A."'

6. An empirical analysis of structural neuroimaging profiles in a staging model of depression

Author

Nogovitsyn, Nikita, Ballester, Pedro, Lasby, Mike, Dunlop, Katharine, Ceniti, Amanda K., Squires, Scott, Rowe, Jessie, Ho, Keith, Suh, JeeSu, Hassel, Stefanie, Souza, Roberto, Casseb, Raphael F., Harris, Jacqueline K., Zamyadi, Mojdeh, Arnott, Stephen R., Strother, Stephen C., Hall, Geoffrey, Lam, Raymond W., Poppenk, Jordan, Lebel, Catherine, Bray, Signe, Metzak, Paul, MacIntosh, Bradley J., Goldstein, Benjamin I., Wang, JianLi, Rizvi, Sakina J., MacQueen, Glenda, Addington, Jean, Harkness, Kate L., Rotzinger, Susan, Kennedy, Sidney H., and Frey, Benicio N.

Published
2024
Full Text
View/download PDF

10. Offshore decommissioning horizon scan: Research priorities to support decision-making activities for oil and gas infrastructure

Author

Watson, Sarah M., McLean, Dianne L., Balcom, Brian J., Birchenough, Silvana N.R., Brand, Alison M., Camprasse, Elodie C.M., Claisse, Jeremy T., Coolen, Joop W.P., Cresswell, Tom, Fokkema, Bert, Gourvenec, Susan, Henry, Lea-Anne, Hewitt, Chad L., Love, Milton S., MacIntosh, Amy E., Marnane, Michael, McKinley, Emma, Micallef, Shannon, Morgan, Deborah, Nicolette, Joseph, Ounanian, Kristen, Patterson, John, Seath, Karen, Selman, Allison G.L., Suthers, Iain M., Todd, Victoria L.G., Tung, Aaron, and Macreadie, Peter I.

Published
2023
Full Text
View/download PDF

21. Altimetry for the future: Building on 25 years of progress

Author

Abdalla, Saleh, Abdeh Kolahchi, Abdolnabi, Ablain, Michaël, Adusumilli, Susheel, Aich Bhowmick, Suchandra, Alou-Font, Eva, Amarouche, Laiba, Andersen, Ole Baltazar, Antich, Helena, Aouf, Lotfi, Arbic, Brian, Armitage, Thomas, Arnault, Sabine, Artana, Camila, Aulicino, Giuseppe, Ayoub, Nadia, Badulin, Sergei, Baker, Steven, Banks, Chris, Bao, Lifeng, Barbetta, Silvia, Barceló-Llull, Bàrbara, Barlier, François, Basu, Sujit, Bauer-Gottwein, Peter, Becker, Matthias, Beckley, Brian, Bellefond, Nicole, Belonenko, Tatyana, Benkiran, Mounir, Benkouider, Touati, Bennartz, Ralf, Benveniste, Jérôme, Bercher, Nicolas, Berge-Nguyen, Muriel, Bettencourt, Joao, Blarel, Fabien, Blazquez, Alejandro, Blumstein, Denis, Bonnefond, Pascal, Borde, Franck, Bouffard, Jérôme, Boy, François, Boy, Jean-Paul, Brachet, Cédric, Brasseur, Pierre, Braun, Alexander, Brocca, Luca, Brockley, David, Brodeau, Laurent, Brown, Shannon, Bruinsma, Sean, Bulczak, Anna, Buzzard, Sammie, Cahill, Madeleine, Calmant, Stéphane, Calzas, Michel, Camici, Stefania, Cancet, Mathilde, Capdeville, Hugues, Carabajal, Claudia Cristina, Carrere, Loren, Cazenave, Anny, Chassignet, Eric P., Chauhan, Prakash, Cherchali, Selma, Chereskin, Teresa, Cheymol, Cecile, Ciani, Daniele, Cipollini, Paolo, Cirillo, Francesca, Cosme, Emmanuel, Coss, Steve, Cotroneo, Yuri, Cotton, David, Couhert, Alexandre, Coutin-Faye, Sophie, Crétaux, Jean-François, Cyr, Frederic, d’Ovidio, Francesco, Darrozes, José, David, Cedric, Dayoub, Nadim, De Staerke, Danielle, Deng, Xiaoli, Desai, Shailen, Desjonqueres, Jean-Damien, Dettmering, Denise, Di Bella, Alessandro, Díaz-Barroso, Lara, Dibarboure, Gerald, Dieng, Habib Boubacar, Dinardo, Salvatore, Dobslaw, Henryk, Dodet, Guillaume, Doglioli, Andrea, Domeneghetti, Alessio, Donahue, David, Dong, Shenfu, Donlon, Craig, Dorandeu, Joël, Drezen, Christine, Drinkwater, Mark, Du Penhoat, Yves, Dushaw, Brian, Egido, Alejandro, Erofeeva, Svetlana, Escudier, Philippe, Esselborn, Saskia, Exertier, Pierre, Fablet, Ronan, Falco, Cédric, Farrell, Sinead Louise, Faugere, Yannice, Femenias, Pierre, Fenoglio, Luciana, Fernandes, Joana, Fernández, Juan Gabriel, Ferrage, Pascale, Ferrari, Ramiro, Fichen, Lionel, Filippucci, Paolo, Flampouris, Stylianos, Fleury, Sara, Fornari, Marco, Forsberg, Rene, Frappart, Frédéric, Frery, Marie-laure, Garcia, Pablo, Garcia-Mondejar, Albert, Gaudelli, Julia, Gaultier, Lucile, Getirana, Augusto, Gibert, Ferran, Gil, Artur, Gilbert, Lin, Gille, Sarah, Giulicchi, Luisella, Gómez-Enri, Jesús, Gómez-Navarro, Laura, Gommenginger, Christine, Gourdeau, Lionel, Griffin, David, Groh, Andreas, Guerin, Alexandre, Guerrero, Raul, Guinle, Thierry, Gupta, Praveen, Gutknecht, Benjamin D., Hamon, Mathieu, Han, Guoqi, Hauser, Danièle, Helm, Veit, Hendricks, Stefan, Hernandez, Fabrice, Hogg, Anna, Horwath, Martin, Idžanović, Martina, Janssen, Peter, Jeansou, Eric, Jia, Yongjun, Jia, Yuanyuan, Jiang, Liguang, Johannessen, Johnny A., Kamachi, Masafumi, Karimova, Svetlana, Kelly, Kathryn, Kim, Sung Yong, King, Robert, Kittel, Cecile M.M., Klein, Patrice, Klos, Anna, Knudsen, Per, Koenig, Rolf, Kostianoy, Andrey, Kouraev, Alexei, Kumar, Raj, Labroue, Sylvie, Lago, Loreley Selene, Lambin, Juliette, Lasson, Léa, Laurain, Olivier, Laxenaire, Rémi, Lázaro, Clara, Le Gac, Sophie, Le Sommer, Julien, Le Traon, Pierre-Yves, Lebedev, Sergey, Léger, Fabien, Legresy, Benoı̂t, Lemoine, Frank, Lenain, Luc, Leuliette, Eric, Levy, Marina, Lillibridge, John, Liu, Jianqiang, Llovel, William, Lyard, Florent, Macintosh, Claire, Makhoul Varona, Eduard, Manfredi, Cécile, Marin, Frédéric, Mason, Evan, Massari, Christian, Mavrocordatos, Constantin, Maximenko, Nikolai, McMillan, Malcolm, Medina, Thierry, Melet, Angelique, Meloni, Marco, Mertikas, Stelios, Metref, Sammy, Meyssignac, Benoit, Minster, Jean-François, Moreau, Thomas, Moreira, Daniel, Morel, Yves, Morrow, Rosemary, Moyard, John, Mulet, Sandrine, Naeije, Marc, Nerem, Robert Steven, Ngodock, Hans, Nielsen, Karina, Nilsen, Jan Even Øie, Niño, Fernando, Nogueira Loddo, Carolina, Noûs, Camille, Obligis, Estelle, Otosaka, Inès, Otten, Michiel, Oztunali Ozbahceci, Berguzar, P. Raj, Roshin, Paiva, Rodrigo, Paniagua, Guillermina, Paolo, Fernando, Paris, Adrien, Pascual, Ananda, Passaro, Marcello, Paul, Stephan, Pavelsky, Tamlin, Pearson, Christopher, Penduff, Thierry, Peng, Fukai, Perosanz, Felix, Picot, Nicolas, Piras, Fanny, Poggiali, Valerio, Poirier, Étienne, Ponce de León, Sonia, Prants, Sergey, Prigent, Catherine, Provost, Christine, Pujol, M-Isabelle, Qiu, Bo, Quilfen, Yves, Rami, Ali, Raney, R. Keith, Raynal, Matthias, Remy, Elisabeth, Rémy, Frédérique, Restano, Marco, Richardson, Annie, Richardson, Donald, Ricker, Robert, Ricko, Martina, Rinne, Eero, Rose, Stine Kildegaard, Rosmorduc, Vinca, Rudenko, Sergei, Ruiz, Simón, Ryan, Barbara J., Salaün, Corinne, Sanchez-Roman, Antonio, Sandberg Sørensen, Louise, Sandwell, David, Saraceno, Martin, Scagliola, Michele, Schaeffer, Philippe, Scharffenberg, Martin G., Scharroo, Remko, Schiller, Andreas, Schneider, Raphael, Schwatke, Christian, Scozzari, Andrea, Ser-giacomi, Enrico, Seyler, Frederique, Shah, Rashmi, Sharma, Rashmi, Shaw, Andrew, Shepherd, Andrew, Shriver, Jay, Shum, C.K., Simons, Wim, Simonsen, Sebatian B., Slater, Thomas, Smith, Walter, Soares, Saulo, Sokolovskiy, Mikhail, Soudarin, Laurent, Spatar, Ciprian, Speich, Sabrina, Srinivasan, Margaret, Srokosz, Meric, Stanev, Emil, Staneva, Joanna, Steunou, Nathalie, Stroeve, Julienne, Su, Bob, Sulistioadi, Yohanes Budi, Swain, Debadatta, Sylvestre-baron, Annick, Taburet, Nicolas, Tailleux, Rémi, Takayama, Katsumi, Tapley, Byron, Tarpanelli, Angelica, Tavernier, Gilles, Testut, Laurent, Thakur, Praveen K., Thibaut, Pierre, Thompson, LuAnne, Tintoré, Joaquín, Tison, Céline, Tourain, Cédric, Tournadre, Jean, Townsend, Bill, Tran, Ngan, Trilles, Sébastien, Tsamados, Michel, Tseng, Kuo-Hsin, Ubelmann, Clément, Uebbing, Bernd, Vergara, Oscar, Verron, Jacques, Vieira, Telmo, Vignudelli, Stefano, Vinogradova Shiffer, Nadya, Visser, Pieter, Vivier, Frederic, Volkov, Denis, von Schuckmann, Karina, Vuglinskii, Valerii, Vuilleumier, Pierrik, Walter, Blake, Wang, Jida, Wang, Chao, Watson, Christopher, Wilkin, John, Willis, Josh, Wilson, Hilary, Woodworth, Philip, Yang, Kehan, Yao, Fangfang, Zaharia, Raymond, Zakharova, Elena, Zaron, Edward D., Zhang, Yongsheng, Zhao, Zhongxiang, Zinchenko, Vadim, and Zlotnicki, Victor

Published
2021
Full Text
View/download PDF

22. White matter microstructure in youth at risk for serious mental illness: A comparative analysis

Author

Shakeel, Mohammed K, Hassel, Stefanie, Davis, Andrew D, Metzak, Paul D, MacQueen, Glenda M, Arnott, Stephen R, Bray, Signe, Frey, Benicio N., Goldstein, Benjamin I., Hall, Geoffrey B, Harris, Jacqueline, Lam, Raymond W, MacIntosh, Bradley J., Milev, Roumen, Mueller, Daniel J, Rotzinger, Susan, Strother, Stephen C, Wang, JianLi, Zamyadi, Mojdeh, Kennedy, Sidney H, Addington, Jean, and Lebel, Catherine

Published
2021
Full Text
View/download PDF

37. MICROSTRUCTURAL CHANGES IN THE PENUMBRAS OF CEREBRAL SMALL VESSEL DISEASE LESIONS ARE ASSOCIATED WITH COGNITION AND SLEEP

Author

Ramirez, Joel, Walker, Kirstin, McSweeney, Melissa, Akhavein, Hassan, Holmes, Melissa F., Ozzoude, Miracle, Scott, Christopher JM, Gao, Fuqiang, Haddad, Seyyed MH, McLaughlin, Paula, Levine, Brian, Kwan, Donna, Montero-Odasso, Manuel, Finger, Elizabeth, McIlroy, William E, Lang, Anthony E., Tartaglia, Maria C., Mandzia, Jennifer, MacIntosh, Bradley J, Freedman, Morris, Rabin, Jennifer, Strother, Stephen C., Masellis, Mario, Symons, Sean, Bartha, Robert, Lim, Andrew, Swartz, Richard H, Black, Sandra E, and Goubran, Maged

Published
2024
Full Text
View/download PDF

39. Neurodevelopmental outcomes in a cohort of Australian families with self-limited familial epilepsy of neonatal/infantile onset.

Author

Innes, Emily A, Marne, Fleur Annette Le, Macintosh, Rebecca, Nevin, Suzanne M., Briggs, Nancy E, Vivekanandarajah, Sinthu, Webster, Richard I, Sachdev, Rani K, and Bye, Ann M E

Abstract

• The majority (93 %) of families had a positive molecular genetic diagnosis. • Ten people (20 %) had recurrent seizures, 12–13 years from last childhood seizure. • Seven children had global developmental delay (14 %), 5 (10 %) had Autism. • The majority (82 %) have average adaptive functioning. • Predictors of adverse outcomes were high seizure burden & longer epilepsy duration. To determine: i) seizure recurrence; ii) developmental disability; iii) co-morbidities and risk factors in self-limited familial neonatal and/or infantile epilepsy (SeLFE) in a multigenerational study. Families were retrospectively recruited from epilepsy databases (2021–2022) in 2 paediatric hospitals, Sydney, Australia. Eligible families had 2 first degree relatives with seizures and underwent genetic testing. Demographics/clinical data were collected from interviews and medical records. Vineland Adaptive Behaviour Scales-Third Edition measured adaptive function. Fifteen families participated. Fourteen had a genetic diagnosis (93%): 11 pathogenic; PRRT2 (n =4), KCNQ2 (n =3), SCN2A (n =4), 3 likely pathogenic; KCNQ2 (n =1), SCN8A (n =2). Seizures affected 73 individuals (ages 1–76 years); 30 children and 20 adults had in-depth phenotyping. Ten of 50 individuals (20%) had seizure recurrence, aged 8–65 years. Median time from last neonatal/infantile seizure was 11.8/12.8 years. Predictors of recurrence were high seizure number (p =0.05) and longer treatment duration (p =0.03). Seven children had global developmental delay (GDD): mild (n =4), moderate (n =1) and severe (n =2). Vineland-3 identified 3 had low-average and 3 had mild-moderately impaired functioning. The majority (82%) were average. GDD was associated with older age at last seizure (p =0.03), longer epilepsy duration (p =0.02), and higher number of anti-seizure medications (p =0.05). Four children had speech delay, 5 (10%) had Autism Spectrum Disorder. Paroxysmal kinesiogenic dyskinesia (n =5) occurred in 4 families and hemiplegic migraine (n =8) in 3 families. Individuals with SeLFE have a small risk of recurrent seizures (20%) and neurodevelopmental disability. Significant predictors are higher seizure number and longer epilepsy duration. Developmental surveillance is imperative. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

41. Recapitulation of POLR3-related hypomyelinating leukodystrophy phenotypes in mice using a PDGFRΑ-dependent POLR3B exon-loss genetic model

Author

Michell-Robinson, Mackenzie, Watt, Kristin, Grouza, Vladimir, Macintosh, Julia, Pinard, Maxime, Tuznik, Marius, Chen, Xiaoru, Darbelli, Lama, Wu, Chia-Lun, Perrier, Stefanie, Chitsaz, Daryan, Uccelli, Nonthue, Liu, Hanwen, Cox, Timothy, Mueller, Christoph, Kennedy, Timothy, Coulombe, Benoit, Rudko, David, Trainor, Paul, and Bernard, Geneviève

Published
2023
Full Text
View/download PDF

44. Biomarkers and cardiovascular events in patients with stable coronary disease in the ISCHEMIA Trials.

Author

Newman, Jonathan D., Anthopolos, Rebecca, Ruggles, Kelly V., Cornwell, Macintosh, Reynolds, Harmony R., Bangalore, Sripal, Mavromatis, Kreton, Held, Claes, Wallentin, Lars, Kullo, Iftikar J., McManus, Bruce, Newby, L. Kristin K．, Rosenberg, Yves, Hochman, Judith S., Maron, David J., and Berger, Jeffrey S.

Abstract

Biomarkers may improve prediction of cardiovascular events for patients with stable coronary artery disease (CAD), but their importance in addition to clinical tests of inducible ischemia and CAD severity is unknown. To evaluate the prognostic value of multiple biomarkers in stable outpatients with obstructive CAD and moderate or severe inducible ischemia. The ISCHEMIA and ISCHEMIA CKD trials randomized 5,956 participants with CAD to invasive or conservative management from July 2012 to January 2018; 1,064 participated in the biorepository. Primary outcome was cardiovascular death, myocardial infarction (MI), or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. Secondary outcome was cardiovascular death or MI. Improvements in prediction were assessed by cause-specific hazard ratios (HR) and area under the receiver operating characteristics curve (AUC) for an interquartile increase in each biomarker, controlling for other biomarkers, in a base clinical model of risk factors, left ventricular ejection fraction (LVEF) and ischemia severity. Secondary analyses were performed among patients in whom core-lab confirmed severity of CAD was ascertained by computed cardiac tomographic angiography (CCTA). Baseline levels of interleukin-6 (IL-6), high sensitivity troponin T (hsTnT), growth differentiation factor 15 (GDF-15), N-terminal pro-B-type natriuretic peptide (NT-proBNP), lipoprotein a (Lp[a]), high sensitivity C-reactive protein (hsCRP), Cystatin C, soluble CD 40 ligand (sCD40L), myeloperoxidase (MPO), and matrix metalloproteinase 3 (MMP3). Among 757 biorepository participants, median (IQR) follow-up was 3 (2-5) years, age was 67 (61-72) years, and 144 (19%) were female; 508 had severity of CAD by CCTA available. In an adjusted multimarker model with hsTnT, GDF-15, NT-proBNP and sCD40L, the adjusted HR for the primary outcome per interquartile increase in each biomarker was 1.58 (95% CI 1.22, 2.205), 1.60 (95% CI 1.16, 2.20), 1.61 (95% 1.22, 2.14), and 1.46 (95% 1.12, 1.90), respectively. The adjusted multimarker model also improved prediction compared with the clinical model, increasing the AUC from 0.710 to 0.792 (P <.01) and 0.714 to 0.783 (P <.01) for the primary and secondary outcomes, respectively. Similar findings were observed after adjusting for core-lab confirmed atherosclerosis severity. Among ISCHEMIA biorepository participants, biomarkers of myocyte injury/distension, inflammation, and platelet activity improved cardiovascular event prediction in addition to risk factors, LVEF, and assessments of ischemia and atherosclerosis severity. These biomarkers may improve risk stratification for patients with stable CAD. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

45. "Somewhere to turn to with my questions": A pre-post pilot of an information linker service for caregivers who have a child with a Developmental and Epileptic Encephalopathy.

Author

Robertson, Eden G., Roberts, Natalie J., Le Marne, Fleur, Beavis, Erin, Macintosh, Rebecca, Kelada, Lauren, Best, Stephanie, Goranitis, Ilias, Pierce, Kristine, Gill, Deepak, Sachdev, Rani, Bye, Ann, and Palmer, Elizabeth E.

Subjects
SERVICES for caregivers, INFORMATION services, CHILDREN with epilepsy, BRAIN diseases, INFORMATION needs
Abstract

Caregivers of a child with a Developmental and Epileptic Encephalopathy (DEE) often report challenges accessing relevant and understandable information regarding their child's condition. We developed GenE Compass, an information linker service where caregivers are invited to submit questions and receive high-quality, personalised reports. We conducted a pilot evaluation to determine the feasibility and acceptability of GenE Compass. We invited eligible caregivers to complete a baseline questionnaire (Q1) prior to receiving three months access to submit an unlimited number of questions to GenE Compass. We then invited caregivers to complete a follow-up questionnaire (Q2) and optional interview. Caregivers also had the opportunity to share report-specific feedback at the time of receiving each report. Seventy-two caregivers completed Q1, of which 41 submitted at least one question (range = 1–7). We received a total of 76 questions. The median turnaround time was 12 working days for our information linker (range = 1–28). Thirty-seven caregivers completed Q2, of whom 32 submitted at least one question (87 %). Overall, caregivers were highly satisfied with GenE Compass and their reports, and indicated that they would use it in the future if they had another question. Caregivers' qualitative data from Q1 and interviews highlighted the ongoing need for an information linker service like GenE Compass due to a lack of understandable information and limited resources, and the benefit in reducing burden of constant information searching. Our study shows that GenE Compass is feasible with the appropriate allocation of resources and highly acceptable to caregivers who have a child with a DEE. [Display omitted] • GenE Compass is an information linker service for caregivers to ask questions about their child's DEE. • Caregivers submitted questions about their child's condition and received personalised reports with evidence-based information. • GenE Compass is feasible to deliver provided the necessary resources are available. • GenE Compass is acceptable to caregivers and highly valued for addressing unmet information needs. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results