Abstract: Dynamic cropping systems, which involve a long-term strategy of annual crop sequencing, require detailed information on management components known to influence crop performance. Considering that proper sequencing of crops is an important component for successful dynamic cropping systems, a research project was undertaken to determine the advantages and/or disadvantages of previous crop and crop residues for numerous crop sequences. A multi-disciplinary team of scientists evaluated crop sequence effects of 10 crops (barley, canola, crambe, dry bean, dry pea, flax, safflower, soybean, spring wheat, and sunflower) on seed yield, soil coverage by residue, soil water use, surface soil properties, and plant diseases in central North Dakota. Two years were required to establish a crop by crop residue matrix (crop matrix). During the second year (site 1, 1999; site 2, 2000) 10 crops were evaluated with a crop matrix. During the third and fourth year spring wheat (site 1, 2000; site 2, 2001) and sunflower (site 1, 2001; site 2, 2002), respectively, were seeded over the crop matrix. The seed yield of four crops (crambe, flax, safflower, and soybean) of the 10 crops evaluated in the crop matrix was influenced by the preceding crop at site 1 in 1999 an above average moisture year. The seed yield of eight crops (canola, crambe, dry bean, flax, safflower, soybean, spring wheat, and barley) was influenced by the preceding crop at site 2 in 2000 a more average precipitation year. Some of the lowest seed yields were obtained when a crop was seeded on its own residue. A synthesis of seed yield data from a given year provided overall values for positive and negative effects of crops and crop residue on subsequent crops. In general, the three legume crops had positive effects in contrast to non-leguminous crops, which usually had negative effects. However, sunflower was an exception among the non-leguminous crops; at site 2 in 2000, sunflower was positive for subsequent crops compared with canola or crambe, which had negative effects. Crop sequences composed of small cereal grains had the highest soil coverage by residue while sequences of two dicotyledonous species had considerably lower coverage. Soil water use among crops varied, ranging from sunflower with the numerically highest soil water use to dry pea with the least. Significant changes in surface soil properties due to crops were generally not detected in this short-term project. Given the variation in Sclerotinia disease incidence for canola, crambe, safflower, and sunflower within the crop matrix, it was difficult to detect significant differences based on the previous crop. Differences were evident two years later when the highest incidence of Sclerotinia basal stalk rot for sunflower was detected in plots where crambe was grown two years earlier. During the third year, when spring wheat was seeded over a crop matrix, spring wheat yields increased following 23 and 19 crop sequence treatments out of a possible 100 at site 1 and site 2, respectively, compared to the continuous wheat treatment. All crop sequence treatments that yielded better than the continuous wheat treatment were comprised of mostly non-cereal crops, demonstrating the positive impact of crop diversity on cereal crop production. The severity of leaf spot diseases on spring wheat were affected by crop sequence and fungal spore production was greatest on the continuous wheat treatment. Even though decreases in leaf spot disease severity and modest yield increases were obtained with some crop sequence treatments, significant yield increases due to reduced leaf spot disease severity were not obtained under our conditions. [Copyright &y& Elsevier]