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6. Impact of diabetes on epicardial reperfusion and mortality in a contemporary STEMI population undergoing mechanical reperfusion: Insights from the ISACS STEMI COVID 19 registry

Author

De Luca, Giuseppe, Algowhary, Magdy, Uguz, Berat, Oliveira, Dinaldo C., Ganyukov, Vladimir, Zimbakov, Zan, Cercek, Miha, Jensen, Lisette Okkels, Loh, Poay Huan, Calmac, Lucian, Roura i Ferrer, Gerard, Quadros, Alexandre, Milewski, Marek, D'Uccio, Fortunato Scotto, von Birgelen, Clemens, Versaci, Francesco, Berg, Jurrien Ten, Casella, Gianni, Lung, Aaron Wong Sung, Kala, Petr, Díez Gil, José Luis, Carrillo, Xavier, Dirksen, Maurits, Becerra-Munoz, Victor M., Lee, Michael Kang-yin, Juzar, Dafsah Arifa, Moura Joaquim, Rodrigo de, Paladino, Roberto, Milicic, Davor, Davlouros, Periklis, Bakraceski, Nikola, Zilio, Filippo, Donazzan, Luca, Kraaijeveld, Adriaan, Galasso, Gennaro, Arpad, Lux, Lucia, Marinucci, Vincenzo, Guiducci, Menichelli, Maurizio, Scoccia, Alessandra, Yamac, Aylin Hatice, Mert, Kadir Ugur, Rios, Xacobe Flores, Kovarnik, Tomas, Kidawa, Michal, Moreu, Josè, Flavien, Vincent, Fabris, Enrico, Martínez-Luengas, Iñigo Lozano, Ojeda, Francisco Bosa, Rodríguez-Sanchez, Robert, Caiazzo, Gianluca, Cirrincione, Giuseppe, Kao, Hsien-Li, Forés, Juan Sanchis, Vignali, Luigi, Pereira, Helder, Manzo, Stephane, Ordoñez, Santiago, Özkan, Alev Arat, Scheller, Bruno, Lehtola, Heidi, Teles, Rui, Mantis, Christos, Antti, Ylitalo, Silveira, João António Brum, Zoni, Rodrigo, Bessonov, Ivan, Savonitto, Stefano, Kochiadakis, George, Alexopulos, Dimitrios, Uribe, Carlos E., Kanakakis, John, Faurie, Benjamin, Gabrielli, Gabriele, Gutierrez Barrios, Alejandro, Bachini, Juan Pablo, Rocha, Alex, Tam, Frankie Chor-Cheung, Rodriguez, Alfredo, Lukito, Antonia Anna, Bellemain-Appaix, Anne, Pessah, Gustavo, Cortese, Giuliana, Parodi, Guido, Burgadha, Mohammed Abed, Kedhi, Elvin, Lamelas, Pablo, Suryapranata, Harry, Nardin, Matteo, and Verdoia, Monica

Published
2024
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16. Female Patients Undergoing Latarjet Surgery Show Similar 2-Year Secondary Surgery Rates but Greater Risk of Emergency Department Visits Compared With a Matched Cohort of Male Patients.

Author

Gillinov, Stephen M., Islam, Wasif, Modrak, Maxwell, Mahatme, Ronak J., Wilhelm, Christopher V., McLaughlin, William M., Surucu, Serkan, Moran, Jay, Lee, Michael S., Grauer, Jonathan N., and Jimenez, Andrew E.

Abstract

To evaluate sex-based differences in 30-day postoperative emergency department (ED) visits, 90-day complication rates, and 2-year secondary surgery rates after the Latarjet procedure for the treatment of recurrent shoulder instability. A national administrative claims database was used to identify patients with International Classification of Diseases, Tenth Revision (ICD-10) diagnosis codes for shoulder subluxation or dislocation on the day of first-time stabilization with the Latarjet technique between 2015 and 2021. Male patients were matched 4:1 to female patients based on age, Elixhauser Comorbidity Index (ECI) score, and body mass index class. Rates of 30-day ED visits and 90-day complications were compared between cohorts, and risk factors for ED visits were identified by multivariate regression. The incidence of secondary surgery within 2 years was compared by Kaplan-Meier analysis. Prior to matching, 1,059 male and 360 female patients met the inclusion and exclusion criteria. Subsequent 4:1 (male-to-female) matching controlling for age, ECI score, and body mass index yielded 694 male and 185 female patients who underwent the Latarjet procedure. The overall incidence of 30-day ED visits was 9.3%, with an incidence of 8.2% for male patients and 13.5% for female patients. On the basis of multivariate logistic regression, these 30-day ED visits were associated with female sex (odds ratio, 1.79; P =.029) and incrementally higher ECI scores; relative to an ECI score of 0, ECI scores of 1 to 2, 3 to 4, and 5 or greater were associated with odds ratios of 5.31 (P =.006), 8.12 (P <.001), and 12.84 (P <.001), respectively. Ninety-day complications occurred in 1.5% of the total cohort, and the incidence was not statistically different between sexes. Overall, 2-year secondary surgery rates were similar between male and female patients (5.1% and 6.7%, respectively; P =.4). Female patients undergoing the Latarjet procedure for recurrent shoulder instability showed similar 90-day complication and 2-year secondary surgery rates to a matched cohort of male patients. Female sex, along with ECI score, however, was associated with a greater rate of 30-day ED visits. Level III, retrospective comparative case series. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Notch signaling: Its essential roles in bone and craniofacial development

Author

Pakvasa, Mikhail, Haravu, Pranav, Boachie-Mensah, Michael, Jones, Alonzo, Coalson, Elam, Liao, Junyi, Zeng, Zongyue, Wu, Di, Qin, Kevin, Wu, Xiaoxing, Luo, Huaxiu, Zhang, Jing, Zhang, Meng, He, Fang, Mao, Yukun, Zhang, Yongtao, Niu, Changchun, Wu, Meng, Zhao, Xia, Wang, Hao, Huang, Linjuan, Shi, Deyao, Liu, Qing, Ni, Na, Fu, Kai, Lee, Michael J., Wolf, Jennifer Moriatis, Athiviraham, Aravind, Ho, Sherwin S., He, Tong-Chuan, Hynes, Kelly, Strelzow, Jason, El Dafrawy, Mostafa, and Reid, Russell R.

Published
2021
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21. Mortality, Safety, and Effectiveness of Paclitaxel-Containing Balloons and Stents in the Femoropopliteal Artery: Systematic Review and Meta-Analysis of Randomized Controlled Trials since 2018.

Author

Briody, Hayley, Kearns, Conor A., and Lee, Michael J.

Abstract

To provide an updated systematic review and meta-analysis of safety and effectiveness outcomes with paclitaxel-containing devices. A systematic review and meta-analysis of randomized controlled trials (RCTs) investigating paclitaxel-containing balloons or stents in the treatment of femoropopliteal disease was performed. Pooled risk ratio (RR) was calculated using the inverse-variance, random-effects model in the assessment of primary patency, all-cause mortality, target limb major amputation, target lesion revascularization (TLR), and thrombosis. In total, 19 RCTs were included comprising 4,284 participants. All-cause mortality rates did not differ significantly between the 2 arms at 12 months (RR, 1.06; 95% confidence interval [CI], 0.66–1.72; P =.80), 24 months (RR, 0.92; 95% CI, 0.56–1.50; P =.73), 36 months (RR, 1.21; 95% CI, 0.65–2.25; P =.55), or 48–60 months (RR, 0.95; 95% CI, 0.66–1.39; P =.81) after intervention. Primary patency was significantly higher at 12 months in the paclitaxel-containing arm: 80.92% (1,438/1,777) versus 57.48% (607/1,056) in the control arm (RR, 1.44; 95% CI, 1.30–1.59; P <.00001). The present study demonstrates no statistically significant difference in all-cause mortality, target limb major amputation, or thrombosis with paclitaxel drug-eluting therapy to the femoropopliteal region. Additionally, improved and durable patency rates with a statistically significantly lower risk of clinically driven TLR with paclitaxel drug-eluting therapy have been demonstrated. [Display omitted] [ABSTRACT FROM AUTHOR]

Published
2024
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22. Corticosteroid Injections Administered Within 4 Weeks Prior to Hip Arthroscopy Are Associated With Higher Rates of Postoperative Infection.

Author

Surucu, Serkan, Halperin, Scott J., Monahan, Peter F., Gillinov, Stephen M., Lee, Michael S., Grauer, Jonathon N., and Jimenez, Andrew E.

Abstract

To evaluate the association between the timing of intra-articular hip corticosteroid injections and the risk of postoperative infection in patients undergoing hip arthroscopy. The 2010-2021 PearlDiver M157 administrative claims database was queried for patients who underwent hip arthroscopy. Patients who received intra-articular corticosteroid injections within 12 weeks prior to arthroscopy were matched 1:1 to patients who did not receive such injections based on age, sex, and Elixhauser Comorbidity Index, as well as the presence of diabetes mellitus, hypertension, obesity, and tobacco use. Those with injections prior to arthroscopy were subdivided based on having received injections within 12 weeks prior to surgery. To verify that the corticosteroid injections and surgical procedures were conducted in the hip joint, Current Procedural Terminology codes were used. By use of Current Procedural Terminology and International Classification of Diseases (ninth revision and tenth revision) coding, postoperative surgical-site infection after corticosteroid injection was evaluated. The impact of the timing of preoperative corticosteroid injections on the incidence of postoperative infection was evaluated using multivariable logistic regression analysis. A total of 12,390 hip arthroscopy cases were identified, including 3,579 patients who received corticosteroid injections 0 to 4 weeks prior to surgery; 4,759, within 4 to 8 weeks prior to surgery; and 4,052, within 8 to 12 weeks prior to surgery. Compared with controls, patients who received corticosteroid injections within 0 to 4 weeks preoperatively had a significantly higher rate of surgical-site infection (odds ratio, 2.43; P =.0001). No significant differences in infection rates were observed at the later time intervals (4-8 weeks or 8-12 weeks). Furthermore, in comparison to controls, patients who received corticosteroid injections had a significantly higher rate of wound dehiscence (odds ratio, 1.84; P =.0007). Intra-articular corticosteroid injections within 4 weeks prior to hip arthroscopy were significantly associated with increased surgical-site infection rates after hip arthroscopy surgery. Level III, retrospective comparative study. [ABSTRACT FROM AUTHOR]

Published
2024
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23. A Qualitative Systematic Review of Endovascular Management of Renal Artery Aneurysms.

Author

Sheahan, Kevin P., Alam, Imran, Pehlivan, Tugche, Pasqui, Edoardo, Briody, Hayley, Kok, Hong Kuan, Asadi, Hamed, and Lee, Michael J.

Abstract

To perform a qualitative systematic review of endovascular management of renal artery aneurysms (RAAs). A comprehensive electronic search of PubMed, MEDLINE, Embase, Google Scholar, and Cochrane databases from 2000 to 2022 was performed using the search terms "renal artery," "aneurysm," and "endovascular." Means of outcome measures were calculated with a primary end point focused on RAA-related mortality and rupture. Secondary end points included reintervention rate and renal infarction. Twenty-six, single-center, retrospective, observational studies were included. There were 454 RAAs treated in 427 patients using endovascular techniques. Mean age was 53.8 years, with a female predominance (62%). A variety of endovascular treatments of RAA were used with excellent technical success (96%), renal parenchymal preservation, and a low rate of moderate/severe adverse events (AEs). Primary coil embolization was the most commonly used technique (44.7%). There was an overall AE rate of 22.9%, of which 6.7% were moderate/severe and there was 0% periprocedural mortality. The most common AE was renal infarction (49 patients, 11.5%); however, renal function was preserved in 84% of patients. Nephrectomy rate was 0.4%. Computed tomography (CT) angiography was the most common imaging follow-up modality used in 72% of studies. Only 9 studies (34%) reported anticoagulant use. Although the risk of delayed aneurysm reperfusion warrants clinical and imaging surveillance, relatively few patients (3%) required reintervention in this cohort. Endovascular management of RAA is a technically feasible treatment option with low rates of AEs and reintervention. The present study highlights the techniques available for interventional radiologists, a need for standardization of AE reporting, anticoagulation therapy, and follow-up imaging. [Display omitted] [ABSTRACT FROM AUTHOR]

Published
2024
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24. 1-Year COMBO stent outcomes stratified by the PARIS bleeding prediction score: From the MASCOT registry

Author

Chandrasekhar, Jaya, Baber, Usman, Sartori, Samantha, Aquino, Melissa B., Hájek, Petr, Atzev, Borislav, Hudec, Martin, Kiam Ong, Tiong, Mates, Martin, Borisov, Borislav, Warda, Hazem M., den Heijer, Peter, Wojcik, Jaroslaw, Iniguez, Andres, Coufal, Zdeněk, Khashaba, Ahmed, Munawar, Muhammad, Gerber, Robert T., Yan, Bryan P., Tejedor, Paula, Kala, Petr, Bang Liew, Houng, Lee, Michael, Kalkman, Deborah N., Dangas, George D., de Winter, Robbert J., Colombo, Antonio, and Mehran, Roxana

Published
2020
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25. A reverse transcriptase-mediated ribosomal RNA depletion (RTR2D) strategy for the cost-effective construction of RNA sequencing libraries

Author

Zeng, Zongyue, Huang, Bo, Wang, Xi, Fan, Jiaming, Zhang, Bo, Yang, Lijuan, Feng, Yixiao, Wu, Xiaoxing, Luo, Huaxiu, Zhang, Jing, Zhang, Meng, He, Fang, Mao, Yukun, Pakvasa, Mikhail, Wagstaff, William, Li, Alexander J., Liu, Bin, Ding, Huimin, Zhang, Yongtao, Niu, Changchun, Wu, Meng, Zhao, Xia, Wolf, Jennifer Moriatis, Lee, Michael J., Huang, Ailong, Luu, Hue H., Haydon, Rex C., and He, Tong-Chuan

Published
2020
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26. Highly expressed BMP9/GDF2 in postnatal mouse liver and lungs may account for its pleiotropic effects on stem cell differentiation, angiogenesis, tumor growth and metabolism

Author

Liu, Wei, Deng, Zhongliang, Zeng, Zongyue, Fan, Jiaming, Feng, Yixiao, Wang, Xi, Cao, Daigui, Zhang, Bo, Yang, Lijuan, Liu, Bin, Pakvasa, Mikhail, Wagstaff, William, Wu, Xiaoxing, Luo, Huaxiu, Zhang, Jing, Zhang, Meng, He, Fang, Mao, Yukun, Ding, Huiming, Zhang, Yongtao, Niu, Changchun, Haydon, Rex C., Luu, Hue H., Wolf, Jennifer Moriatis, Lee, Michael J., Huang, Wei, He, Tong-Chuan, and Zou, Yulong

Published
2020
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27. 1-year results after PCI with the COMBO stent in all-comers in Asia versus Europe: Geographical insights from the COMBO collaboration

Author

Chandrasekhar, Jaya, Kalkman, Deborah N., Aquino, Melissa B., Sartori, Samantha, Hájek, Petr, Atzev, Borislav, Hudec, Martin, Ong, Tiong Kiam, Mates, Martin, Borisov, Borislav, Warda, Hazem M., den Heijer, Peter, Wojcik, Jaroslaw, Iñiguez, Andrés, Coufal, Zdeněk, Khashaba, Ahmed, Schee, Alexandr, Munawar, Muhammad, Gerber, Robert T., Yan, Bryan P., Tejedor, Paula, Kala, Petr, Liew, Houng Bang, Lee, Michael, Baber, Usman, Vogel, Birgit, Dangas, George D., Colombo, Antonio, de Winter, Robbert J., and Mehran, Roxana

Published
2020
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32. Stem cell therapy for chronic skin wounds in the era of personalized medicine: From bench to bedside

Author

Coalson, Elam, Bishop, Elliot, Liu, Wei, Feng, Yixiao, Spezia, Mia, Liu, Bo, Shen, Yi, Wu, Di, Du, Scott, Li, Alexander J., Ye, Zhenyu, Zhao, Ling, Cao, Daigui, Li, Alissa, Hagag, Ofir, Deng, Alison, Liu, Winny, Li, Mingyang, Haydon, Rex C., Shi, Lewis, Athiviraham, Aravind, Lee, Michael J., Wolf, Jennifer Moriatis, Ameer, Guillermo A., He, Tong-Chuan, and Reid, Russell R.

Published
2019
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33. The wonders of BMP9: From mesenchymal stem cell differentiation, angiogenesis, neurogenesis, tumorigenesis, and metabolism to regenerative medicine

Author

Mostafa, Sami, Pakvasa, Mikhail, Coalson, Elam, Zhu, Allen, Alverdy, Alex, Castillo, Hector, Fan, Jiaming, Li, Alex, Feng, Yixiao, Wu, Di, Bishop, Elliott, Du, Scott, Spezia, Mia, Li, Alissa, Hagag, Ofir, Deng, Alison, Liu, Winny, Li, Mingyang, Ho, Sherwin S., Athiviraham, Aravind, Lee, Michael J., Wolf, Jennifer Moriatis, Ameer, Guillermo A., Luu, Hue H., Haydon, Rex C., Strelzow, Jason, Hynes, Kelly, He, Tong-Chuan, and Reid, Russell R.

Published
2019
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34. Transcriptomic landscape regulated by the 14 types of bone morphogenetic proteins (BMPs) in lineage commitment and differentiation of mesenchymal stem cells (MSCs)

Author

Zhang, Linghuan, Luo, Qing, Shu, Yi, Zeng, Zongyue, Huang, Bo, Feng, Yixiao, Zhang, Bo, Wang, Xi, Lei, Yan, Ye, Zhenyu, Zhao, Ling, Cao, Daigui, Yang, Lijuan, Chen, Xian, Liu, Bin, Wagstaff, William, Reid, Russell R., Luu, Hue H., Haydon, Rex C., Lee, Michael J., Wolf, Jennifer Moriatis, Fu, Zhou, He, Tong-Chuan, and Kang, Quan

Published
2019
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36. Safety and efficacy of the COMBO bio-engineered stent in an all-comer PCI cohort: 1-Year final clinical outcomes from the MASCOT post-marketing registry

Author

Colombo, Antonio, Chandrasekhar, Jaya, Aquino, Melissa, Ong, Tiong Kiam, Sartori, Samantha, Baber, Usman, Lee, Michael, Iniguez, Andres, Hajek, Petr, Borisov, Borislav, Atzev, Borislav, Den Heijer, Peter, Coufal, Zdenek, Hudec, Martin, Mates, Martin, Snyder, Clayton, Moalem, Kamilia, Morrell, Deborah, Elmore, Francesca, Rowland, Stephen, and Mehran, Roxana

Published
2019
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37. Patients Undergoing Revision Hip Arthroscopy With Labral Reconstruction or Augmentation Demonstrate Favorable Patient Reported Outcomes: A Systematic Review.

Author

Lee, Michael S., Fong, Scott, Lee, Amy Y., Norman, Mackenzie, Mahatme, Ronak J., Pettinelli, Nicholas, Park, Nancy, Gagné, Jack, Gillinov, Stephen M., Islam, Wasif, and Jimenez, Andrew E.

Abstract

To review current literature evaluating patient-reported outcomes (PROs) and survivorship in patients undergoing revision hip arthroscopy with labral reconstruction or augmentation. A systematic review was performed with the following key words: (revision) AND (hip OR femoroacetabular impingement) AND (arthroscopy OR arthroscopic) AND (reconstruction OR augmentation OR irreparable). PubMed, Cochrane Trials, and Scopus were queried in October 2022 using the criteria established in the Preferred Reporting Items for Systematic Reviews and Meta-analyses. Studies were included if they involved patients undergoing revision hip arthroscopy with labral reconstruction or augmentation and reported preoperative and postoperative PROs at minimum 2-year follow-up. Only original research articles were included. Survivorship was defined as a nonconversion to total hip arthroplasty. Outcomes present in 3 or more studies underwent further statistical analysis with forest plots. Heterogeneity of studies was evaluated using the I 2 statistic. Five studies were reviewed, including 359 revision hip arthroscopies (335 with complete follow-up) with a follow-up that ranged from 2.2 to 5.2 years. Four studies reported on outcomes after revision labral reconstruction and 1 study reported on labral augmentation. Two out of 5 included studies evaluated for statistical significance between preoperative and postoperative outcomes. Three out of 5 studies reported a rate of at least 70% for achieving minimal clinically important difference in at least 1 PRO. At minimum 2-year follow-up, survivorship ranged from 93.5% to 100%. Patients that underwent revision hip arthroscopy with labral reconstruction or augmentation demonstrated improvement in PROs with mixed rates of achieving clinical benefit and rates of survivorship at minimum 2-year follow-up ranging from 93.5% to 100%. Level IV, systematic review of level III to IV studies. [ABSTRACT FROM AUTHOR]

Published
2024
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40. Characterization of the essential role of bone morphogenetic protein 9 (BMP9) in osteogenic differentiation of mesenchymal stem cells (MSCs) through RNA interference

Author

Yan, Shujuan, Zhang, Ruyi, Wu, Ke, Cui, Jing, Huang, Shifeng, Ji, Xiaojuan, An, Liping, Yuan, Chengfu, Gong, Cheng, Zhang, Linghuan, Liu, Wei, Feng, Yixiao, Zhang, Bo, Dai, Zhengyu, Shen, Yi, Wang, Xi, Luo, Wenping, Liu, Bo, Haydon, Rex C., Lee, Michael J., Reid, Russell R., Wolf, Jennifer Moriatis, Shi, Qiong, Luu, Hue H., He, Tong-Chuan, and Weng, Yaguang

Published
2018
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46. Effect of ascending aortic dimension on acute procedural success following self-expanding transcatheter aortic valve replacement: A multicenter retrospective analysis

Author

Maeno, Yoshio, Yoon, Sung-Han, Abramowitz, Yigal, Watanabe, Yusuke, Jilaihawi, Hasan, Lin, Mao-Shin, Chan, Jason, Sharma, Rahul, Kawashima, Hideyuki, Israr, Sharjeel, Kawamori, Hiroyuki, Miyasaka, Masaki, Rami, Tanya, Kazuno, Yoshio, Mangat, Geeteshwar, Kashif, Mohammad, Chakravarty, Tarun, Kao, Hsien-Li, Lee, Michael Kang-yin, Nakamura, Mamoo, Kozuma, Ken, Cheng, Wen, and Makkar, Raj R.

Published
2017
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