8 results on '"Lam, Mary K."'
Search Results
2. Cloning of the MHC class II DRB cDNA from the brushtail possum ( Trichosurus vulpecula)
- Author
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Lam, Mary K.-P., Belov, Katherine, Harrison, Gavan A., and Cooper, Desmond W.
- Published
- 2001
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3. Predictors of 12 month functional outcomes and length of stay of severely injured children in NSW, Australia. A longitudinal multi-centre study.
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Curtis, Kate, Kennedy, Belinda, Lam, Mary K, Mitchell, Rebecca J, Black, Deborah, Jan, Stephen, Burns, Brian, Dinh, Michael, and Holland, Andrew JA
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WOUND care , *LENGTH of stay in hospitals , *RESEARCH , *TRAUMA centers , *RESEARCH methodology , *EVALUATION research , *COMPARATIVE studies , *QUALITY of life , *QUESTIONNAIRES - Abstract
Background: The majority of paediatric injury outcomes studies focus on mortality rather than the impact on long-term quality of life, health care use and other health-related outcomes. This study sought to determine predictors of 12-month functional and psychosocial outcomes for children sustaining major injury in NSW.Methods: The study included all children < 16 years requiring intensive care or an injury severity score (ISS) ≥ 9 treated in NSW at a paediatric trauma centre (PTC). Children were identified through the three PTCs and NSW Trauma Registry. The paediatric Quality of Life Inventory (PedsQL) and EuroQol five-dimensional EQ-5D-Y were used to measure HRQoL post-injury, completed via parent/carer proxy recruited through NSW PTCs.Results: There were 510 children treated at the three NSW PTCs during the 15-month study period. The mean (SD) age was 6.7 (6.0) years, with a median NISS (New Injury Severity Score) of 11 (IQR: 9-18). Regression analysis showed worse psychosocial health at twelve months was associated with hospital length of stay (LoS) and number of body regions injured (F2,65 = 5.85, p = 0.005). Physical outcome was associated with LoS and intensive care unit (ICU) admission (F2,66 = 13.48, p < 0.001). Hospital LoS was significantly associated with NISS and head injury (F2,398 = 51.5, p < 0.001).Conclusion: Hospital length of stay and polytrauma are independent factors that negatively influence psychological and physical outcomes of children with major injuries. Early intervention to enable emotional well-being, discharge home and long-term follow up such as dedicated family support and rehabilitation at home could reduce preventable poor outcomes. [ABSTRACT FROM AUTHOR]- Published
- 2022
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4. Pathways and factors that influence time to definitive trauma care for injured children in New South Wales, Australia.
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Curtis, Kate, Kennedy, Belinda, Lam, Mary K, Mitchell, Rebecca J, Black, Deborah, Burns, Brian, Dinh, Michael, and Holland, Andrew JA
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CHILD care , *HEALTH facilities , *MEDICAL registries , *METROPOLIS , *TRAUMA registries , *TRAUMA centers - Abstract
Background: Timely definitive paediatric trauma care influences patient and parental physical and emotional outcomes. New South Wales (NSW) covers a large geographical area with all three NSW paediatric trauma centres (PTC) located in two approximated major cities, meaning it is inevitable that some injured children receive initial treatment locally and then require transfer. Little is known about the factors that then impact timely arrival of injured children to definitive care.Methods: This included children admitted between July 2015 and September 2016, <16 years with an injury severity (ISS) ≥9; or requiring intensive care admission; or deceased following injury. Children were identified through the three PTCs, NSW Trauma Registry and NSW Medical Retrieval Registry.Results: There were 593 children admitted following injury and 46% required transfer to a PTC. There was no significant difference in age, ISS, ICU admission or head injury (AIS >2) between transferred and directly transported cohorts. There were significant differences in mechanism of injury between the two groups (χ2(9) = 45.9, p < 0.001). The median (IQR) time to book a transfer from arrival at the referring facility, was 146.5 (86-238) minutes. Time from injury to arrival at the PTC more than doubled for children transferred, with significant and unwarranted variability between transporting agencies resulting in unwarranted delays to surgical intervention. For example, time spent at the referring facility by Aeromedical Retrieval Service was less than half that of the Newborn & paediatric Emergency Transport Service [53 (IQR:47-61) vs 115 (84-155) minutes (p <0.001)].Conclusion: Clinicians caring for paediatric trauma patients in facilities outside trauma centres require the capability and opportunity to identify and notify early those requiring transfer for ongoing management. The provision of a streamlined referral and transfer process for all paediatric trauma patients requiring treatment in NSW PTCs would reduce the burden on the referring facility, reduce variation amongst transport providers and improve time to definitive care. [ABSTRACT FROM AUTHOR]- Published
- 2022
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5. Prehospital care and transport costs of severely injured children in NSW Australia.
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Curtis, Kate, Kennedy, Belinda, Lam, Mary K., Mitchell, Rebecca J., Black, Deborah, Burns, Brian, Loudfoot, Allan, Tall, Gary, Dinh, Michael, Beech, Clare, and Holland, Andrew J.A.
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EMERGENCY medical services , *MEDICAL care costs , *TRAUMA registries , *MEDICAL registries , *OXYGEN therapy , *TRAUMA centers , *WOUND care , *RETROSPECTIVE studies , *TRAUMA severity indices , *WOUNDS & injuries - Abstract
Background: Injury is the leading cause of childhood death and disability in Australia. Prehospital emergency services in New South Wales (NSW) are provided by NSW Ambulance. The incidence, pre-hospital care provided and outcomes of children suffering major injury in NSW has not previously been described.Methods: This retrospective study was conducted between July 2015 and September 2016 and included children <16 years with an injury severity score (ISS) >9, or requiring intensive care admission, or deceased following injury and treated in NSW. Children were identified through the three NSW Paediatric Trauma Centres, the NSW Trauma Registry, NSW Medical Retrieval Registry (AirMaestro, Avinet, Australia).Results: There were 359 majorly injured children treated by NSW-based emergency service providers, the majority were male (73.3%) with a mean (SD) age of 8.0 (5.2) years. The median (IQR) injury severity score (ISS) for those transported via NSW emergency medical services was 10 (9-17), with almost half (44.1%) treated prehospital having an ISS >12. The most common documented interventions were intravenous access (44.1%) and oxygen therapy (39.6%). Intubation and chest decompression were recorded in 15.3% and 3.1% of cases respectively. The calculated median (IQR) transport charges for NSW Emergency Services was AUD $942 ($841.3-$1184.6).Conclusion: Critical interventions are performed infrequently in children with major injuries in the pre-hospital environment. The monitoring of the incidence and success rates for staff performing these interventions is not readily available from all prehospital emergency medical services operating in NSW. The capacity and processes to monitor and audit all critical interventions in the paediatric population should be resourced and clearly defined. [ABSTRACT FROM AUTHOR]- Published
- 2020
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6. Cause, treatment costs and 12-month functional outcomes of children with major injury in NSW, Australia.
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Curtis, Kate, Kennedy, Belinda, Lam, Mary K., Mitchell, Rebecca J., Black, Deborah, Burns, Brian, White, Leslie, Loudfoot, Allan, D'Amato, Alfa, Dinh, Michael, and Holland, Andrew J.A.
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RURAL children , *QUALITY of life , *TRAUMA registries , *METROPOLIS , *WOUNDS & injuries , *WOUND care , *MEDICAL care costs , *TRAUMA severity indices , *LONGITUDINAL method - Abstract
Background: Information about children treated in New South Wales (NSW), Australia following major injury has been limited to those treated at trauma centres using mortality as the main outcome measure, restricting assessment of the effectiveness of the Trauma System. This study sought to describe the detailed characteristics as well as functional and psychosocial health outcomes of all children suffering major injury in NSW.Methods: A longitudinal study was conducted between July 2015 and November 2017 and included children < 16 years requiring intensive care or an injury severity score (ISS) ≥ 9 treated in NSW or who died following injury. Children were identified through the three NSW Paediatric Trauma Centres (PTC), the NSW Trauma Registry, NSW Aeromedical Retrieval Registry (AirMaestro) and the National Coronial Information System (NCIS). Health-related quality of life (HRQoL) outcomes for children treated at the three PTCs were collected at baseline, 6 and 12 months using the Paediatric Quality of Life inventory (PedsQL 4.0) and EuroQol five-dimensional EQ-5D-Y.Results: There were 625 children, with a median (interquartile range) age of 7 (2-13) years and 71.7% were male. Around half were injured in major cities (51.2%). The median (IQR) injury severity score (ISS) was 10 (9-17). Twelve-month HRQoL measured by PedsQL remained below baseline for psychosocial health. Treatment costs increased with injury severity (p=<0.001) and polytrauma (p=<0.001). No survival benefit was demonstrated between PTC versus non-PTC definitive care. Injured females and children from rural / remote NSW were overrepresented in the deceased.Conclusion: Children treated in NSW following major injury have reduced quality of life and in particular, reduced emotional well-being at 12 months post-injury. Improved psychosocial care and outpatient follow-up is required to minimise the long-term emotional impact of injury on the child. [ABSTRACT FROM AUTHOR]- Published
- 2020
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7. Simulation-based multidisciplinary team training decreases time to critical operations for trauma patients.
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Murphy, Margaret, Curtis, Kate, Lam, Mary K., Palmer, Cameron S., Hsu, Jeremy, and McCloughen, Andrea
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COMPUTER simulation , *TRAINING , *TRAUMATISM , *DRUG delivery systems , *HEALTH programs , *THERAPEUTICS - Abstract
Background: Simulation has been promoted as a platform for training trauma teams. However, it is not clear if this training has an impact on health service delivery and patient outcomes. This study evaluates the association between implementation of a simulation based multidisciplinary trauma team training program at a metropolitan trauma centre and subsequent patient outcomes.Method: This was a retrospective review of trauma registry data collected at an 850-bed Level 1 Adult Trauma Centre in Sydney, Australia. Two concurrent four-year periods, before and after implementation of a simulation based multidisciplinary trauma team training program were compared for differences in time to critical operations, Emergency Department (ED) length of stay (LOS) and patient mortality.Results: There were 2389 major trauma patients admitted to the hospital during the study, 1116 in the four years preceding trauma team training (the PREgroup) and 1273 in the subsequent 4 years (the POST group). There were no differences between the groups with respect to gender, body region injured, incidence of polytrauma, and pattern of arrival to ED. The POST group was older (median age 54 versus 43 years, p < 0.001) and had a higher incidence of falls and assaults (p < 0.001). There was a reduction in time to critical operation, from 2.63 h (IQR 1.23-5.12) in the PRE-group to 0.55 h (IQR 0.22-1.27) in the POST-group, p < 0.001. The overall ED LOS increased, and there was no reduction in mortality. Post-hoc analysis found LOS in ED was reduced in the cohort requiring critical operations, p < 0.001.Conclusion: The implementation of trauma team training was associated with a reduction in time to critical operation while overall ED length of stay increased. Simulation is promoted as a platform for training teams; but the complexity of trauma care challenges efforts to demonstrate direct links between multidisciplinary team training and improved outcomes. There remain considerable gaps in knowledge as to how team training impacts health service delivery and patient outcomes.Level Of Evidence: Retrospective comparative therapeutic/care management study, Level III evidence. [ABSTRACT FROM AUTHOR]- Published
- 2018
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8. Response to Letter to the Editor from Carmo et al. re Pathways and factors that influence time to definitive trauma care for injured children in New South Wales, Australia.
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Curtis, Kate, Holland, Andrew JA, Black, Deborah, Burns, Brian, Mitchell, Rebecca J, Dinh, Michael, Kennedy, Belinda, and Lam, Mary K
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CHILD care , *TIME - Published
- 2021
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