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Your search keyword '"La Barbera D"' showing total 7 results
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7 results on '"La Barbera D"'

1. The influence of risk factors on the onset and outcome of psychosis: What we learned from the GAP study

Author

Murray, R.M., Mondelli, V., Stilo, S.A., Trotta, A., Sideli, L., Ajnakina, O., Ferraro, L., Vassos, E., Iyegbe, C., Schoeler, T., Bhattacharyya, S., Marques, T.R., Dazzan, P., Lopez-Morinigo, J., Colizzi, M., O'Connor, J., Falcone, M.A., Quattrone, D., Rodriguez, V., Tripoli, G., La Barbera, D., La Cascia, C., Alameda, L., Trotta, G., Morgan, C., Gaughran, F., David, A., and Di Forti, M.

Published
2020
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2. Real-world effectiveness of long acting aripiprazole: Treatment persistence and its correlates in the Italian clinical practice

Author

Fagiolini, A., Aguglia, E., Ballerini, A., Callista, G., Carpiniello, B., Clerici, M., Corrivetti, G., De Fazio, P., De Filippis, S., De Giorgi, S., Favaretto, G., Ferri, E., Gargiulo, G., Giustra, M.G., La Barbera, D., Maina, G., Mencacci, C., Montagnani, G., Panariello, A., Pigato, G., Tortorella, A., Vernacotola, L., and Vita, A.

Published
2019
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5. 23. Resting state functional magnetic resonance imaging analysis of the brain of pathological gamblers.

Author

Collura, G., Marrale, M., Gagliardo, C., Maniaci, G., Piccoli, T., La Tona, G., La Cascia, C., La Barbera, D., Picone, F., Lagalla, R., and Cannizzaro, C.

Abstract

Purpose Gambling disorder has been recently reclassified under the category "substance-related and addictive disorders". Recent studies performed through functional MRI (fMRI) have shown that the perseverance of some behaviors can alter brain activation [1,2]. In this work we aim at investigating functional connectivity changes in pathological gamblers (PGs) in comparison to healthy controls (HCs) by means of resting state functional Magnetic Resonance Imaging (rs-fMRI). Methods and materials Thirteen HCs and fourteen PGs were recruited (all right handed males; drugs free; mean age 36 ± 10 yrs). All acquisitions were performed through a 1,5 T MRI scanner using a 8-channels phased-array head coil. Multi-session temporal concatenated Independent Component Analysis (concat-ICA) was carried out to achieve activations information on functionally linked brain regions. The resulted components were then matched and compared between groups. Correction for multiple comparisons across space was applied assuming an overall significance of p < 0.05 using permutation testing and threshold-free cluster enhancement. Results Functional connectivity was found to be increased in PGs, compared to HCs, in several networks including: anterior cingulate cortex, accumbens nucleus, head of the caudate nucleus, middle left temporal gyrus, right insula, right cerebellar hemisphere cortex and cerebellar vermis. Conclusion We can conclude that an hyperconnectivity together with an overactivation of specific regions is observed in PGs. The persistent activation of specific functional networks during gambling tasks might represent the neurofunctional basis of PGs state-reduced triggering threshold to gaming underlying the clinical features of gambling disorder. These preliminary results confirms the crucial role of fMRI studies to investigate brain networks and their changes in specific clinical functional disorders. [ABSTRACT FROM AUTHOR]

Published
2018
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7. IQ differences between patients with first episode psychosis in London and Palermo reflect differences in patterns of cannabis use

Author

Robin M. Murray, Diego Quattrone, Marta Di Forti, Laura Ferraro, Giada Tripoli, Daniele La Barbera, Caterina La Cascia, Lucia Sideli, Ferraro L., Murray R.M., Di Forti M., Quattrone D., Tripoli G., Sideli L., La Barbera D., and La Cascia C.

Subjects
Adult, Cross-Cultural Comparison, Male, Psychosis, medicine.medical_specialty, Adolescent, Intelligence, Neurodevelopment, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Cognition, First episode psychosis, London, medicine, Settore MED/48 -Scienze Infermierist. e Tecn. Neuro-Psichiatriche e Riabilitat, Humans, Cognitive Dysfunction, In patient, Cannabi, Psychiatry, Cognitive impairment, Settore MED/25 - Psichiatria, Biological Psychiatry, Multicentric study, biology, business.industry, Confounding, Cannabis use, medicine.disease, biology.organism_classification, 030227 psychiatry, Psychiatry and Mental health, Italy, Psychotic Disorders, Risk factors, Case-Control Studies, Female, Marijuana Use, Cannabis, business, 030217 neurology & neurosurgery
Abstract

Aims: Cognitive impairment is a possible indicator of neurodevelopmental impairment, but not all psychotic patients are cognitively compromised. It has been suggested that heavy cannabis use may precipitate psychosis in those who show no such compromise. This study compares two samples of patients with first-episode psychosis and their respective non-psychotic controls, in London (UK) and Palermo (Italy), and examines whether different patterns of cannabis use are reflected in differences in IQ. Methods: The two studies used the same inclusion/exclusion criteria and instruments. The sample comprised 249 subjects from London (106 patients and 143 controls) and 247 subjects from Palermo (120 patients and 127 controls). ANCOVA was performed with IQ as the dependent variable and city and frequency of cannabis use as predictors. This was then repeated with the case group only, by adjusting for relevant confounders. Results: We found a greater amount of cannabis use in the London sample, compared to Palermo and patients from London had higher IQ than patients from Palermo, a difference that was more significant than that reflected between controls (Fjavax.xml.bind.JAXBElement@68a50fa4(1, 402) = 7.6, p = 0.006). Once corrected for symptomatology and treatment, patients from London who had never used cannabis were similar to patients from Palermo regarding IQ. Thus the higher IQ of patients from London was mainly due to the subgroup of cannabis-using patients (Fcannabis*city(2,145) = 4.6, p = 0.011). Conclusions: We can speculate that a greater amount of cannabis-use may have contributed by precipitating psychosis in patients with a higher IQ in London but less so in patients from Palermo.

Published
2019

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