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Your search keyword '"L. Bellan"' showing total 3 results
Start Over Author "L. Bellan" Publisher elsevier b.v.
3 results on '"L. Bellan"'

1. Chemical structure of native and modified sulfated heterorhamnans from the green seaweed Gayralia brasiliensis and their cytotoxic effect on U87MG human glioma cells

Author

Mazepa, Ester, Noseda, Miguel D., Ferreira, Luciana G., de Carvalho, Mariana M., Gonçalves, Alan G., Ducatti, Diogo R.B., de L. Bellan, Daniel, Gomes, Rafaela P., da S. Trindade, Edvaldo, Franco, Célia R.C., Pellizzari, Franciane M., Winnischofer, Sheila M.B., and Duarte, Maria E.R.

Published
2021
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2. Structure elucidation of a bioactive fucomannogalactan from the edible mushroom Hypsizygus marmoreus

Author

Sthefany Rodrigues Fernandes Viana, Luciano M. Lião, Stellee Marcela Petris Biscaia, E. S. Trindade, Maria Carolina Di Medeiros Leal, D. L. Bellan, Ana Flora Dalberto Vasconcelos, Ruberney S. Oliveira, Elaine R. Carbonero, Universidade Federal de Goiás (UFG), Univ Fed Parana, and Universidade Estadual Paulista (Unesp)

Subjects
Polymers and Plastics, B16-F10 cell, Chemical structure, Mannose, Antineoplastic Agents, 02 engineering and technology, 010402 general chemistry, Cell morphology, Galactans, 01 natural sciences, Fucose, Mushroom, chemistry.chemical_compound, Cell Movement, Cell Line, Tumor, Materials Chemistry, Animals, Fruiting Bodies, Fungal, Molecular Structure, Organic Chemistry, Hypsizygus marmoreus, 021001 nanoscience & nanotechnology, In vitro, 0104 chemical sciences, Molecular Weight, Edible mushroom, Biochemistry, chemistry, Fucomannogalactan, Galactose, Antimelanoma, Agaricales, 0210 nano-technology
Abstract

Made available in DSpace on 2019-10-04T12:42:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01 Made available in DSpace on 2019-10-04T12:42:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-12-01 Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) A fucomannogalactan (FMG-Hm), with a molecular weight of 17.1 kDa, obtained from fruiting bodies of Hypsizygus marmoreus exhibited promising in vitro antimelanoma effects. FMG-Hm was not cytotoxic, nor did it alter the cell morphology and proliferation, but was able to inhibit colony-forming ability and cell migration in B16-F10 murine melanoma cells. An analysis of the monosaccharide composition indicated that FMG-Hm was composed of fucose, mannose, and galactose in a ratio of 1.00:1.08:3.17. The FMG-Hm was structurally characterized based on methylation analysis, partial acid hydrolysis, and NMR experiments. The results indicated that FMG-Hm contained a alpha-(1 -> 6)-linked galactopyranosyl main chain, partially substituted at O-2 by non-reducing ends of alpha-L-fucopyranose and beta-D-mannopyranose. The predicted structure of the heteropolysaccharide was established as: [GRAPHICS] . Univ Fed Goias, Dept Quim, BR-75704020 Regional Catalao, Catalao, Brazil Univ Fed Parana, Dept Biol Celular, BR-81531980 Curitiba, Parana, Brazil Univ Estadual Paulista, Fac Ciencias Agron, Dept Engn Rural, BR-18610307 Botucatu, SP, Brazil Univ Fed Goias, Inst Quim, Lab Ressonancia Magnet Nucl, Campus Samambaia, BR-74001970 Goiania, Go, Brazil Univ Estadual Paulista, Fac Ciencias & Tecnol, Dept Quim & Bioquim, BR-19060900 Presidente Prudente, Brazil Univ Estadual Paulista, Fac Ciencias Agron, Dept Engn Rural, BR-18610307 Botucatu, SP, Brazil Univ Estadual Paulista, Fac Ciencias & Tecnol, Dept Quim & Bioquim, BR-19060900 Presidente Prudente, Brazil CAPES: 001

Published
2019

3. Structural characteristics of native and chemically sulfated polysaccharides from seaweed and their antimelanoma effects.

Author

Mazepa, Ester, Biscaia, Stellee M.P., de L. Bellan, Daniel, da S. Trindade, Edvaldo, and Simas, Fernanda F.

Subjects
*POLYSACCHARIDES, *GALACTANS, *MARINE algae, *MOLECULAR weights, *SCIENCE databases, *CARRAGEENANS, *CHONDROITIN sulfates
Abstract

Polysaccharides from seaweed have been shown to present a variety of antitumor effects, however the understanding of which structural patterns are responsible for these biological effects are still unclear. This review aimed to gather and critically evaluate published data of seaweed polysaccharide's chemical structure elucidation and their relation with antimelanoma effects. Data were collected at the electronic article databases Science Direct, NCBI/Pubmed and Google Scholar, selecting papers with polysaccharide structural information and biological effects on melanoma models. Most of the papers referred to sulfated polysaccharides as fucans and fucoidans, and to a lesser extent galactans, rhamnans, alginates, and neutral one's glucans. Fine chemical features as presence and position of sulfate groups, monosaccharide composition, linear or branched backbones, and glycosidic linkage type are crucial to antimelanoma effects, as well as molecular weight and macromolecular conformation. [Display omitted] [ABSTRACT FROM AUTHOR]

Published
2022
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