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Abstract: For mobile communication, the ferromagnetic resonance frequency of magnetic films must be over 3GHz. A suitable anisotropic field and high resistivity for high frequency applications were obtained by inserting insulator (AlO x ) layers into ferromagnetic layers (FeCoHfO). With this optimum configuration of three layers structure [FeCoHfO (400nm)/AlO x (10nm)]3, high frequency characteristics (permeability∼100 at 100MHz and ferromagnetic resonance frequency over 3GHz) and high resistivity (ρ ∼1088) μΩcm were achieved. [ABSTRACT FROM AUTHOR]

Abstract: High-permeability magnetic films can enhance the inductance of thin-film inductors in dc–dc converters. The FeCoHfO/AlO x multilayered films were fabricated by dc reactive magnetron co-sputtering. Inserting the AlO x layers can decrease the anisotropic field of the FeCoHfO magnetic films, which was beneficial to raise the permeability of the FeCoHfO/AlO x multilayered films. With this optimum configuration of a nine-layer structure [FeCoHfO (133nm)/AlO x (10nm)]9, low anisotropic field (H K =65Oe) and high permeability (permeability over 170 at 30–50MHz) were obtained. The permeability increased nearly six times from 30 (M1) to 175 (M9). The permeability was evidently improved by the employment multilayered coating. [Copyright &y& Elsevier]

Abstract: To identify transcripts related to high egg production expressed specifically in the hypothalamus and pituitary gland of the chicken, two subtracted cDNA libraries were constructed. Two divergently selected strains of Taiwan Country Chickens (TCCs), B (sire line) and L2 (dam line) were used; they had originated from a single population and were further subjected (since 1982) to selection for egg production to 40 wk of age and body weight/comb size, respectively. A total of 324 and 370 clones were identified from the L2-B (L2-subtract-B) and the B-L2 subtracted cDNA libraries, respectively. After sequencing and annotation, 175 and 136 transcripts that represented 53 known and 65 unknown non-redundant sequences were characterized in the L2-B subtracted cDNA library. Quantitative reverse-transcription (RT)-PCR was used to screen the mRNA expression levels of 32 randomly selected transcripts in another 78 laying hens from five different strains. These strains included the two original strains (B and L2) used to construct the subtracted cDNA libraries and an additional three commercial strains, i.e., Black- and Red-feather TCCs and Single-Comb White Leghorn (WL) layer. The mRNA expression levels of 16 transcripts were significantly higher in the L2 than in the B strain, whereas the mRNA expression levels of nine transcripts, BDH, NCAM1, PCDHA@, PGDS, PLAG1, PRL, SAR1A, SCG2 and STMN2, were significantly higher in two high egg production strains, L2 and Single-Comb WL; this indicated their usefulness as molecular markers of high egg production. [Copyright &y& Elsevier]

Eight-week-old male B6 mice fed with a high-fat diet (HFD) for 12 weeks exhibited characteristics of metabolic disorders, including hyperglycemia, hyperinsulinemia, and hyperlipidemia, as well as depressive symptoms. Implantation with a miniosmotic pump containing glibenclamide (GB), a K ATP channel blocker, into the interscapular BAT of HFD-fed mice improves glucose homeostasis, insulin sensitivity, and depressive symptoms. • Glibenclamide infusion improves glucose homeostasis, insulin sensitivity, and depression-like symptoms. • BAT-K ATP channel expression is lower in HFD-fed mice than in chow-fed mice. • GB infusion in HFD-fed mice restores BAT-K ATP channel expression. • Inhibiting BAT-K ATP channels improves metabolic syndromes and reduces depression-like symptoms. Obesity, a critical feature in metabolic disorders, is associated with medical depression. Recent evidence reveals that brown adipose tissue (BAT) activity may contribute to mood disorders, Adenosine triphosphate (ATP)-sensitive K+ (K ATP) channels regulate BAT sympathetic nerve activity. However, the mechanism through which BAT activity affects mood control remains unknown. We hypothesized the BAT is involved in depressive-like symptoms regulation by trafficking K ATP channels. Eight-week-old male B6 mice fed with a high-fat diet (HFD) for 12 weeks exhibited characteristics of metabolic disorders, including hyperglycemia, hyperinsulinemia, and hyperlipidemia, as well as depressive symptoms. In this study, we surgically removed interscapular BAT in mice, and these mice exhibited immobility in the forced swim test and less preference for sugar water compared with other mice. To delineate the role of K ATP channels in BAT activity regulation, we implanted a miniosmotic pump containing glibenclamide (GB), a K ATP channel blocker, into the interscapular BAT of HFD-fed mice. GB infusion improved glucose homeostasis, insulin sensitivity, and depressive-like symptoms. K ATP channel expression was lower in HFD-fed mice than in chow-fed mice. Notably, GB infusion in HFD-fed mice restored K ATP channel expression. K ATP channels are functionally expressed in BAT, and inhibiting BAT-K ATP channels improves metabolic syndromes and reduces depressive symptoms through beta-3-adrenergic receptor-mediated protein kinase A signaling. [ABSTRACT FROM AUTHOR]