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The past decade has brought enormous changes in scholarly communication, leading many libraries to undertake large-scale digital publishing initiatives. However, no study has investigated how technical services departments are changing to support these new services. Using change management as a theoretical framework, the investigator uses content analysis, surveys, and interviews to analyze how libraries at the cutting edge of library-based digital publishing are utilizing their technical services departments to support these new initiatives and how these changes are being handled. The findings indicate that while many technical services departments are actively supporting library-based digital publishing to some degree, many functions traditionally provided by technical services are being handled by other units within the library. This leads to a discussion of how these change processes will progress and their ultimate effect on library structures and user services. [Copyright &y& Elsevier]

2007 data from LibQUAL+™ and the ACRL Library Trends and Statistics database were analyzed to determine if there is a statistically significant correlation between library expenditures and usage statistics and library patron satisfaction across 73 universities. The results show that users of larger, better funded libraries have higher expectations for information resource availability, but not higher satisfaction scores. Furthermore, the data show no significant correlation between library usage statistics and user satisfaction. The researchers conclude that the lack of expected correlations could be attributed to limitations in the LibQUAL+™ method of measuring patron satisfaction, or the difficulty of using the quantitative measurements found in ACRL statistics to try and accurately predict user satisfaction. [Copyright &y& Elsevier]

Today''s high throughput sequencing approaches, coupled with equally revolutionary advances in bioinformatics, allow us to describe and analyze genomes in unprecedented detail. Short Read Sequencing (SRS) approaches have been especially instrumental in bringing genomic analysis to a wide range of questions and species in plant biology. We can now connect genotypes and phenotypes with greater efficiency, and investigate the molecular basis of natural variation and adaptation in a genomic framework. New and creative applications of SRS and other genomic approaches are not only reshaping how we study natural variation, but also our overall understanding of gene and genome evolution. Here we discuss examples of the application of SRS technologies to the characterization of genetic diversity, genome evolution and adaptation in plants. [Copyright &y& Elsevier]

Statement of problem: Traditional testing of ceramic crowns creates a stress state and damage modes that differ greatly from those seen clinically. There is a need to develop and communicate an in vitro testing protocol that is clinically valid. Purpose: The purpose of this study was to develop an in vitro failure test for ceramic single-unit prostheses that duplicates the failure mechanism and stress state observed in clinically failed prostheses. This article first compares characteristics of traditional load-to-failure tests of ceramic crowns with the growing body of evidence regarding failure origins and stress states at failure from the examination of clinically failed crowns, finite element analysis (FEA), and data from clinical studies. Based on this analysis, an experimental technique was systematically developed and test materials were identified to recreate key aspects of clinical failure in vitro. Material and methods: One potential dentin analog material (an epoxy filled with woven glass fibers; NEMA grade G10) was evaluated for elastic modulus in blunt contact and for bond strength to resin cement as compared to hydrated dentin. Two bases with different elastic moduli (nickel chrome and resin-based composite) were tested for influence on failure loads. The influence of water during storage and loading (both monotonic and cyclic) was examined. Loading piston materials (G10, aluminum, stainless steel) and piston designs were varied to eliminate Hertzian cracking and to improve performance. Testing was extended from a monolayer ceramic (leucite-filled glass) to a bilayer ceramic system (glass-infiltrated alumina). The influence of cyclic rate on mean failure loads was examined (2 Hz, 10 Hz, 20 Hz) with the extremes compared statistically (t test; α=.05). Results: Failure loads were highly influenced by base elastic modulus (t test; P<.001). Cyclic loading while in water significantly decreased mean failure loads (1-way ANOVA; P=.003) versus wet storage/dry cycling (350 N vs. 1270 N). G10 was not significantly different from hydrated dentin in terms of blunt contact elastic behavior or resin cement bond strength. Testing was successful with the bilayered ceramic, and the cycling rate altered mean failure loads only slightly (approximately 5%). Conclusions: Test methods and materials were developed to validly simulate many aspects of clinical failure. [Copyright &y& Elsevier]

Abstract: In an earlier study we disputed the claim that the mediodorsal thalamic nucleus is critical for familiarity. We reported patient (QX) who showed a severe deficit in conscious recollection, and behavioural problems (disinhibition, emotional lability) with relative sparing of familiarity-aware memory following a left mediodorsal thalamic lesion. More recent MR imaging has revealed that QX's lesions are more extensive than previously reported and involve both dorsolateral thalamic nuclei, and whilst there is evidence of left mediodorsal thalamic damage, it is not the main focus of damage. This paper reports a full analysis of QX's thalamic pathology alongside a more detailed investigation of his recognition memory, using yes/no and forced-choice procedures, and executive function. The results revealed impairments in yes/no recognition and conscious recollection rates of famous, artist and unknown names. In addition to the previously noted behavioural disinhibition and emotional lability, a deficit in spontaneous planning ability was evident on the Zoo Map Test (subtest of the Bahavioural Assessment of the Dysexecutive Syndrome). Forced-choice recognition, familiarity estimates and remote memory showed higher levels of preservation. The findings indicate that the dorsolateral thalamus is part of the extended hippocampal circuit which is causally critical only for recall and conscious recollection of complex associations rather than for the more automatic processes linked with novelty detection. [Copyright &y& Elsevier]