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Impression procedures for recording large maxillofacial defects are tedious and difficult because of the unavailability of stock impression trays. This article describes the procedure of fabricating a straightforward facial moulage with predictable accuracy by using a reusable radiotherapy thermoplastic sheet. [ABSTRACT FROM AUTHOR]

Medication-related osteonecrosis of the jaw (MRONJ) is a relatively infrequent but very well-known adverse effect of bisphosphonates. This rare complication of bisphosphonates is rarest with the use of certain drugs. Tyrosine kinase inhibitors (TKIs), particularly used in renal cell carcinoma or gastrointestinal tumors as a chemotherapeutic agent, can precipitate this particular medical condition of bone when it is associated with either radiation or bisphosphonates, though, monodrug therapy with TKIs rarely causes MRONJ. This article describes a rare case of necrosis of the jawbone in a patient with a myeloproliferative neoplasm who was receiving the TKI imatinib and had no history of bisphosphonate or radiation therapy to head and neck region. [ABSTRACT FROM AUTHOR]

Statement of problem Conventional spray and the immersion disinfection of irreversible hydrocolloid impression materials may lead to dimensional changes. Purpose The purpose of this in vitro study was to investigate the antimicrobial activity and properties of irreversible hydrocolloid impression materials incorporated with silver nanoparticles. Materials and methods The antimicrobial activity and properties of 2 commercially available irreversible hydrocolloid impression materials were evaluated after incorporating varying concentrations of silver nanoparticles. Antimicrobial activity was determined using the disk diffusion method. The gel strength, permanent deformation, flow, and gelation time were measured according to American Dental Association specification #18. Analysis of variance was used to identify the significant differences within and across the groups (α=.05). Results Adding silver nanoparticles to irreversible hydrocolloid impression materials resulted in superior antimicrobial activity without adversely affecting their properties. Adding silver nanoparticles to Zelgan significantly increased the gel strength compared with the control group, except at 5 wt%. However, the gel strength of Tropicalgin was unaffected except at 5 wt%. An increase in the permanent deformation was found with the incorporation of silver nanoparticles in both Zelgan and Tropicalgin. The flow of Zelgan increased with the incorporation of silver nanoparticles, whereas a decrease in the flow of Tropicalgin was observed at 1 wt% and 2 wt%. An increase in the gelation time of both Zelgan and Tropicalgin was observed with the incorporation of silver nanoparticles. Conclusions Based on this in vitro study, silver nanoparticles can be incorporated into irreversible hydrocolloid impression materials as antimicrobial agents without adversely affecting their properties. [ABSTRACT FROM AUTHOR]

Objectives The main objective of the present in vitro study is to evaluate the antimicrobial activity and properties of irreversible hydrocolloid impression material incorporated with silver nanoparticles of varying size at different concentrations. Methods Silver nanoparticles of 80–100, 50–80, 30–50 and 10–20 nm size were added to irreversible hydrocolloid impression material at 0.5, 1.0, 2.0 and 5.0 wt%. Antimicrobial activity of the silver nanoparticle incorporated irreversible hydrocolloid was measured using disk diffusion method. The gel strength, flow, gelation time and permanent deformation were measured according to American Dental Association specification #18. Data were analyzed using analysis of variation at a confidence interval of 95% ( α = 0.05). Results Silver nanoparticles of 80–100 nm size have imparted superior antimicrobial activity to the irreversible hydrocolloid in a dose-dependent manner whereas finer nanoparticle size did not exhibit any antimicrobial activity. The addition of silver nanoparticles did not alter the properties of irreversible hydrocolloid at 0.5 and 1.0 wt% whereas at higher concentrations significant differences in flow, gelation time and strength were observed. Significance The results of the present study indicate that silver nanoparticles of size range 80–100 nm are superior in imparting antimicrobial activity to irreversible hydrocolloid compared to finer particle size range. [ABSTRACT FROM AUTHOR]