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Start Over Author "Grishin, Oleg" Publisher elsevier b.v.
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3. Production of new antituberculosis drug and other medical preparations by electron beam treatment

Author

Shkurupiy, Vyacheslav A., Krasnov, Vladimir A., Gulyaeva, Elena P., Troitskiy, Alexander V., Grishin, Oleg V., Bogdanova, Ludmila A., Machneva, Tatyana V., Auslender, Vadim L., and Korobeinikov, Mikhail V.

Subjects
*ISONICOTINIC acid, *ANTITUBERCULAR agents
Abstract

Possibility of electron beam usage for immobilization of hydrazidum of an isonicotinic acid (HIA) on dextrane was studied to produce a drug for treatment of a tuberculosis. As a result of irradiation of dextrane the processes of oxidation and formation of polysaccharide occur due to carbonyl groups which are to link isoniasidum. The HIA immobilized on dextrane may be used as an effective medical preparation having prolonged action for action on endo and extracellular population of Micobacterium tuberculosis. [Copyright &y& Elsevier]

Published
2002
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