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380 results on '"Gencer, A."'

30. Is caregiver burden of patients with amyotrophic lateral sclerosis related to caregivers' mindfulness, quality of life, and patients' functional level.

Author

Ipek, Lutfiye and Güneş Gencer, Gökçe Yağmur

Abstract

• Caregivers of patients with Amyotrophic Lateral Sclerosis (ALS) often experience moderate to severe Caregiver Burden (CB). • The caregiver burden of ALS patients' caregivers tends to increase over time. • The functional decline of ALS patients may negatively affect the quality of life (QoL) of their caregivers and increase their CB. • Mindfulness is a feasible and acceptable intervention that can help reduce CB in caregivers of ALS patients. • Mindfulness can also be an effective intervention to improve the QoL of caregivers. The aim of this study was to evaluate the caregiver burden, mindfulness, and quality of life (QoL) of caregivers of ALS patients and the patient's functional level. This study was conducted with 57 ALS patients and their primary caregivers. The data were collected using the Zarit Burden Interview, Mindful Attention Awareness Scale (MAAS), the Short Form-36 (SF-36), and the ALS Functional Rating Scale (ALS-FRS). The mean age of the caregivers was 49.7 ± 12 years; 66 % were female, and 73.7 % were spouses of the patients. Around 65 % of caregivers experienced a moderate to severe caregiver burden. A low and negative correlation was found between the caregiver burden and mindfulness of caregivers of ALS patients. As the mindfulness levels of the caregivers increased, the caregiver burden decreased, and the physical role difficulty score, one of the sub-dimensions of the QoL, increased. Also, caregivers' QoL decreased as caregiver burden increased (except physical function QoL, p < 0.05). Moreover, there was a positive correlation between the caregiver burden and ALSFRS-R scores (bulbar, motor, respiratory, and total) of the caregivers of ALS patients (p < 0.05). Improved technology for managing ALS disease has increased patient life expectancy. However, caregivers may experience a high burden as the patient's functional level declines. Increasing caregiver mindfulness can help reduce the burden and improve their QoL. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Prognostic value of pulse pressure after an acute coronary syndrome

Author

Harbaoui, Brahim, Nanchen, David, Lantelme, Pierre, Gencer, Baris, Heg, Dick, Klingenberg, Roland, Räber, Lorenz, Carballo, David, Matter, Christian M., Windecker, Stephan, Mach, François, Rodondi, Nicolas, Eeckhout, Eric, Monney, Pierre, Antiochos, Panagiotis, Schwitter, Juerg, Pascale, Patrizio, Fournier, Stephane, Courand, Pierre-Yves, Lüscher, Thomas F., and Muller, Olivier

Published
2018
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45. Pre-hospital alarm activation for STEMI patients undergoing primary percutaneous coronary intervention in the era of transradial procedures

Author

Rigamonti, Fabio, Gencer, Baris, Rey, Florian, Chaara, Jawad, Tessitore, Elena, Bunwaree, Sholan, Meier, Pascal, Noble, Stéphane, Grosgurin, Olivier, Larribau, Robert, Windecker, Stephan, Carbone, Federico, Montecucco, Fabrizio, Rodondi, Nicolas, Matter, Christian M., Luscher, Thomas F., Mach, François, and Roffi, Marco

Published
2016
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49. Misperceptions and management of LDL-cholesterol in secondary prevention of patients with familial hypercholesterolemia in cardiology practice: Real-life evidence from the EPHESUS registry.

Author

Kayıkcioglu, Meral, Başaran, Özcan, Doğan, Volkan, Mert, Kadir Uğur, Mert, Gurbet Özge, Özdemir, İbrahim Halil, Rencüzoğulları, İbrahim, Karadeniz, Fatma Özpamuk, Tekinalp, Mehmet, Aşkın, Lütfü, Demirelli, Selami, Gencer, Erkan, Bekar, Lütfü, Aktaş, Müjdat, Resulzade, Mübariz Murat, Kalçık, Macit, Aksan, Gökhan, Cinier, Göksel, Akay, Kadriye Halli, and Pekel, Nihat

Subjects
THERAPEUTIC use of protease inhibitors, STATINS (Cardiovascular agents), ANTILIPEMIC agents, COMBINATION drug therapy, FAMILIAL hypercholesterolemia, LDL cholesterol, CARDIOVASCULAR diseases, GENETIC disorders, EZETIMIBE, TREATMENT effectiveness, COMPARATIVE studies, DESCRIPTIVE statistics, DISEASE complications, DRUG side effects, TERMINATION of treatment, DISEASE management
Abstract

• In real life, vast majority of FH patients with established ASCVD are undertreated in cardiology outpatient clinics • The proportion of FH patients receiving high intensity statin therapy is very low • Ezetimibe and PCSK9 inhibitor use is almost non-existent • Drug discontinuation rates are notably high and are mostly media-related • Side effects very rarely cause cessation of LLT. • Patients' knowledge about high cholesterol and its treatment is low. Familial hypercholesterolemia (FH) is a common inherited disease, leading to premature atherosclerotic cardiovascular disease (ASCVD) due to elevated low-density lipoprotein cholesterol (LDL-C) levels. Achieving LDL-C goals is extremely important for preventing the complications of this fatal disease. We evaluated the management of FH patients with ASCVD in cardiology practice. We analyzed patients with ASCVD from the nationwide EPHESUS registry, which was conducted in 40 cardiology outpatient clinics, and compared those with and without FH. Of the 1482 consecutively enrolled patients with ASCVD, 618 (41.7%) had FH, among which 455 were categorized as 'Possible FH' and 163 as 'Probable or Definite FH'. Proposed LDL-C goals were not attained in more than 90% of the patients with FH. The proportion of those on statin therapy was 77% for possible and 91% for probable or definite FH, whereas 34.2 % and 59.4% were in use of high-intensity statins, respectively. None of the patients were on PCSK-9 inhibitors, and only 2 used ezetimibe. Adverse media coverage was the most common cause of statin discontinuation (32.5% in 'possible FH' and 45.7% in 'probable/definite FH'). The negative impact of media in the decision to stop lipid lowering therapy (LLT) was increasing with education level. In real life most of the FH patients with ASCVD are undertreated in cardiology practice regarding statin dosing and combined LLT. Drug discontinuation rates are notably high and are mostly media-related, and side effects very rarely cause cessation of LLT. Urgent measures are needed to increase the awareness of FH among healthcare providers and patients and to develop improved treatment strategies aimed at preventing the complications of FH. [Display omitted] [ABSTRACT FROM AUTHOR]

Published
2023
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50. 4D flow magnetic resonance imaging to assess right ventricular outflow tract in patients undergoing transcatheter pulmonary valve replacement.

Author

Karsenty, Clément, Alattar, Yousef, Mousseaux, Elie, Marcilhacy, Gabrielle, Gencer, Umit, Craiem, Damian, Iserin, Laurence, ladouceur, Magalie, Legendre, Antoine, Laredo, Mikael, Bonnet, Damien, Malekzadeh-Milani, Sophie, and Soulat, Gilles

Abstract

Copyright of Revista Española de Cardiología (18855857) is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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