Search

Your search keyword '"Dermawan, Josephine K."' showing total 13 results
Start Over Author "Dermawan, Josephine K." Publisher elsevier b.v.
13 results on '"Dermawan, Josephine K."'

7. YAP1-TFE3-fused hemangioendothelioma: a multi-institutional clinicopathologic study of 24 genetically-confirmed cases.

Author

Dermawan, Josephine K., Azzato, Elizabeth M., Billings, Steven D., Fritchie, Karen J., Aubert, Sebastien, Bahrami, Armita, Barisella, Marta, Baumhoer, Daniel, Blum, Veronika, Bode, Beata, Aesif, Scott W., Bovée, Judith V. M. G., Dickson, Brendan C., van den Hout, Mari, Lucas, David R., Moch, Holger, Oaxaca, Gabriel, Righi, Alberto, Sciot, Raf, and Sumathi, Vaiyapuri

Published
2021
Full Text
View/download PDF

9. DNA Methylation Profiling Distinguishes Adamantinoma-Like Ewing Sarcoma From Conventional Ewing Sarcoma.

Author

Fritchie, Karen J., Ameline, Baptiste, Andrei, Vanghelita, Griffith, Christopher, Shah, Akeesha A., Dermawan, Josephine K., Trucco, Matteo, Budd, Thomas, Thangaiah, Judith J., Molligan, Jeremy, Whaley, Rumeal D., Magliocca, Kelly, Azzato, Elizabeth, van Zante, Annemieke, Jo, Vickie, Xu, Bin, Bishop, Justin A., Rooper, Lisa, and Baumhoer, Daniel

Published
2023
Full Text
View/download PDF

13. Evaluation of deeper levels in initially negative temporal artery biopsies and likelihood of a positive result.

Author

Dermawan, Josephine K. and Prayson, Richard A.

Abstract

Giant cell arteritis is a vasculitis that affects large- and medium-sized vessels in patients over the age of 50 years. The demonstration of granulomatous arteritis is the criterion standard to establish a definitive diagnosis. However, temporal arteritis is known to discontinuously involve the artery, and there is no standardization of the number of sections which should be examined in a length of sampled artery. The goal of the study is to determine, if by examining additional sections from temporal artery (TA) biopsy cases initially interpreted as negative, do we uncover cases of vasculitis. We conducted a retrospective review of the clinical and histologic features of 75 consecutive temporal artery biopsy cases. Our findings showed that the vast majority (94%) of cases that were biopsy "proven" to be negative for temporal arteritis on initial examination remained negative after examination of all subsequent deeper levels (median of 337 total levels examined). These cases were less likely to show classical GCA signs and symptoms and typically presented at a younger age than the biopsy-positive cases. However, 4 (6%) of the initially "biopsy-negative" cases did turn out to be positive on deeper levels, with 56, 109, 346, and 590 total levels examined, respectively. At least 2 of these 4 patients did not receive prednisone or were weaned off prednisone treatment and experienced persistent/recurrent GCA symptoms. We conclude that routine sampling may miss the diagnosis in a subset of cases and in some cases, sectioning deeper into the paraffin block may be warranted. • Temporal arteritis may segmentally involve a blood vessel. • A negative biopsy result with routine sampling does not rule out arteritis. • Complete examination of biopsied tissue occasionally (6% in this study) shows arteritis. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results