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1. Specific Compositions of Amyloid-β Peptides as the Determinant of Toxic β-Aggregation.

Author

Yoshiike, Yuji, De-Hua Chui, Akagi, Takumi, Tanaka, Nobuo, and Takashima, Akihiko

Subjects
*AMYLOID beta-protein, *ALZHEIMER'S disease
Abstract

Studies the specific compositions of amyloid-beta peptides in Alzheimer's disease. Time course of beta-aggregation and toxicity of wild type amyloid-beta40; Mutations in the N-terminal domain of amyloid-beta variants; Roles of the amyloid-beta C terminus and amyloid-beta N terminus in beta-aggregation.

Published
2003
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