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387 results on '"Bick A"'

4. The outcomes and safety of patients undergoing endoscopic retrograde cholangiopancreatography combining a single-use cholangioscope and a single-use duodenoscope: A multicenter retrospective international study

Author

Fugazza, Alessandro, Colombo, Matteo, Kahaleh, Michel, Muthusamy, V. Raman, Benjamin, Bick, Laleman, Wim, Barbera, Carmelo, Fabbri, Carlo, Nieto, Jose, Al-Lehibi, Abed, Ramchandani, Mohan, Tyberg, Amy, Shahid, Haroon, Sarkar, Avik, Ehrlich, Dean, Sherman, Stuart, Binda, Cecilia, Spadaccini, Marco, Iannone, Andrea, Khalaf, Kareem, Reddy, Nageshwar, Anderloni, Andrea, and Repici, Alessandro

Published
2024
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6. The JUNO experiment Top Tracker

Author

Abusleme, Angel, Adam, Thomas, Ahmad, Shakeel, Ahmed, Rizwan, Aiello, Sebastiano, Akram, Muhammad, Aleem, Abid, Alexandros, Tsagkarakis, An, Fengpeng, An, Qi, Andronico, Giuseppe, Anfimov, Nikolay, Antonelli, Vito, Antoshkina, Tatiana, Asavapibhop, Burin, Athayde Marcondes de André, João Pedro, Auguste, Didier, Bai, Weidong, Balashov, Nikita, Baldini, Wander, Barresi, Andrea, Basilico, Davide, Baussan, Eric, Bellato, Marco, Beretta, Marco, Bergnoli, Antonio, Bick, Daniel, Birkenfeld, Thilo, Blin, Sylvie, Blum, David, Blyth, Simon, Bolshakova, Anastasia, Bongrand, Mathieu, Bordereau, Clément, Breton, Dominique, Brigatti, Augusto, Brugnera, Riccardo, Bruno, Riccardo, Budano, Antonio, Busto, Jose, Cabrera, Anatael, Caccianiga, Barbara, Cai, Hao, Cai, Xiao, Cai, Yanke, Cai, Zhiyan, Callier, Stéphane, Cammi, Antonio, Campeny, Agustin, Cao, Chuanya, Cao, Guofu, Cao, Jun, Caruso, Rossella, Cerna, Cédric, Cerrone, Vanessa, Chan, Chi, Chang, Jinfan, Chang, Yun, Chen, Chao, Chen, Guoming, Chen, Pingping, Chen, Shaomin, Chen, Yixue, Chen, Yu, Chen, Zhiyuan, Chen, Zikang, Cheng, Jie, Cheng, Yaping, Cheng, Yu Chin, Chepurnov, Alexander, Chetverikov, Alexey, Chiesa, Davide, Chimenti, Pietro, Chu, Ziliang, Chukanov, Artem, Claverie, Gérard, Clementi, Catia, Clerbaux, Barbara, Colomer Molla, Marta, Conforti Di Lorenzo, Selma, Coppi, Alberto, Corti, Daniele, Corso, Flavio Dal, Dalager, Olivia, De La Taille, Christophe, Deng, Zhi, Deng, Ziyan, Depnering, Wilfried, Diaz, Marco, Ding, Xuefeng, Ding, Yayun, Dirgantara, Bayu, Dmitrievsky, Sergey, Dohnal, Tadeas, Dolzhikov, Dmitry, Donchenko, Georgy, Dong, Jianmeng, Doroshkevich, Evgeny, Dou, Wei, Dracos, Marcos, Drapier, Olivier, Druillole, Frédéric, Du, Ran, Du, Shuxian, Dugas, Katherine, Dusini, Stefano, Duyang, Hongyue, Eck, Jessica, Enqvist, Timo, Fabbri, Andrea, Fahrendholz, Ulrike, Fan, Lei, Fang, Jian, Fang, Wenxing, Fargetta, Marco, Fedoseev, Dmitry, Fei, Zhengyong, Felici, Giulietto, Feng, Li-Cheng, Feng, Qichun, Ferraro, Federico, Fournier, Amélie, Gan, Haonan, Gao, Feng, Garfagnini, Alberto, Gavrikov, Arsenii, Gerasimov, Vladimir, Giammarchi, Marco, Giudice, Nunzio, Gonchar, Maxim, Gong, Guanghua, Gong, Hui, Gornushkin, Yuri, Göttel, Alexandre, Grassi, Marco, Gromov, Maxim, Gromov, Vasily, Gu, Minghao, Gu, Xiaofei, Gu, Yu, Guan, Mengyun, Guan, Yuduo, Guardone, Nunzio, Guo, Cong, Guo, Wanlei, Guo, Xinheng, Guo, Yuhang, Gursky, Semen, Hagner, Caren, Han, Ran, Han, Yang, He, Miao, He, Wei, Heinz, Tobias, Hellmuth, Patrick, Heng, Yuekun, Herrera, Rafael, Hor, YuenKeung, Hou, Shaojing, Hsiung, Yee, Hu, Bei-Zhen, Hu, Hang, Hu, Jianrun, Hu, Jun, Hu, Shouyang, Hu, Tao, Hu, Yuxiang, Hu, Zhuojun, Huang, Guihong, Huang, Hanxiong, Huang, Jinhao, Huang, Kaixuan, Huang, Wenhao, Huang, Qinhua, Huang, Xin, Huang, Xingtao, Huang, Yongbo, Hui, Jiaqi, Huo, Lei, Huo, Wenju, Huss, Cédric, Hussain, Safeer, Ioannisian, Ara, Isocrate, Roberto, Jelmini, Beatrice, Jeria, Ignacio, Ji, Xiaolu, Jia, Huihui, Jia, Junji, Jian, Siyu, Jiang, Di, Jiang, Wei, Jiang, Xiaoshan, Jing, Xiaoping, Jollet, Cécile, Kalousis, Leonidas, Kampmann, Philipp, Kang, Li, Karaparambil, Rebin, Kazarian, Narine, Khan, Ali, Khatun, Amina, Khosonthongkee, Khanchai, Korablev, Denis, Kouzakov, Konstantin, Krasnoperov, Alexey, Kuleshov, Sergey, Kutovskiy, Nikolay, Kuusiniemi, Pasi, Lachenmaier, Tobias, Landini, Cecilia, Leblanc, Sébastien, Lebrin, Victor, Lefevre, Frederic, Lei, Ruiting, Leitner, Rupert, Leung, Jason, Li, Demin, Li, Fei, Li, Fule, Li, Gaosong, Li, Huiling, Li, Mengzhao, Li, Min, Li, Nan, Li, Qingjiang, Li, Ruhui, Li, Rui, Li, Shanfeng, Li, Tao, Li, Teng, Li, Weidong, Li, Weiguo, Li, Xiaomei, Li, Xiaonan, Li, Xinglong, Li, Yi, Li, Yichen, Li, Yufeng, Li, Zepeng, Li, Zhaohan, Li, Zhibing, Li, Ziyuan, Li, Zonghai, Liang, Hao, Liao, Jiajun, Limphirat, Ayut, Lin, Guey-Lin, Lin, Shengxin, Lin, Tao, Ling, Jiajie, Lippi, Ivano, Liu, Caimei, Liu, Fang, Liu, Haidong, Liu, Haotian, Liu, Hongbang, Liu, Hongjuan, Liu, Hongtao, Liu, Hui, Liu, Jianglai, Liu, Jiaxi, Liu, Jinchang, Liu, Min, Liu, Qian, Liu, Qin, Liu, Runxuan, Liu, Shenghui, Liu, Shubin, Liu, Shulin, Liu, Xiaowei, Liu, Xiwen, Liu, Yankai, Liu, Yunzhe, Lokhov, Alexey, Lombardi, Paolo, Lombardo, Claudio, Loo, Kai, Lu, Chuan, Lu, Haoqi, Lu, Jingbin, Lu, Junguang, Lu, Peizhi, Lu, Shuxiang, Lubsandorzhiev, Bayarto, Lubsandorzhiev, Sultim, Ludhova, Livia, Lukanov, Arslan, Luo, Daibin, Luo, Fengjiao, Luo, Guang, Luo, Jianyi, Luo, Shu, Luo, Wuming, Luo, Xiaojie, Lyashuk, Vladimir, Ma, Bangzheng, Ma, Bing, Ma, Qiumei, Ma, Si, Ma, Xiaoyan, Ma, Xubo, Maalmi, Jihane, Magoni, Marco, Mai, Jingyu, Malyshkin, Yury, Mandujano, Roberto Carlos, Mantovani, Fabio, Mao, Xin, Mao, Yajun, Mari, Stefano M., Marini, Filippo, Martini, Agnese, Mayer, Matthias, Mayilyan, Davit, Mednieks, Ints, Meng, Yue, Meraviglia, Anita, Meregaglia, Anselmo, Meroni, Emanuela, Meyhöfer, David, Miller, Jonathan, Miramonti, Lino, Montini, Paolo, Montuschi, Michele, Müller, Axel, Nastasi, Massimiliano, Naumov, Dmitry V., Naumova, Elena, Navas-Nicolas, Diana, Nemchenok, Igor, Nguyen Thi, Minh Thuan, Nikolaev, Alexey, Ning, Feipeng, Ning, Zhe, Nunokawa, Hiroshi, Oberauer, Lothar, Ochoa-Ricoux, Juan Pedro, Olshevskiy, Alexander, Orestano, Domizia, Ortica, Fausto, Othegraven, Rainer, Paoloni, Alessandro, Parmeggiano, Sergio, Pei, Yatian, Pelicci, Luca, Peng, Anguo, Peng, Haiping, Peng, Yu, Peng, Zhaoyuan, Perrot, Frédéric, Petitjean, Pierre-Alexandre, Petrucci, Fabrizio, Pilarczyk, Oliver, Piñeres Rico, Luis Felipe, Popov, Artyom, Poussot, Pascal, Previtali, Ezio, Qi, Fazhi, Qi, Ming, Qian, Sen, Qian, Xiaohui, Qian, Zhen, Qiao, Hao, Qin, Zhonghua, Qiu, Shoukang, Ranucci, Gioacchino, Rasheed, Reem, Re, Alessandra, Rebii, Abdel, Redchuk, Mariia, Ren, Bin, Ren, Jie, Ricci, Barbara, Rifai, Mariam, Roche, Mathieu, Rodphai, Narongkiat, Romani, Aldo, Romanov, Victor, Roskovec, Bedřich, Ruan, Xichao, Rybnikov, Arseniy, Sadovsky, Andrey, Saggese, Paolo, Sandanayake, Deshan, Sanfilippo, Simone, Sangka, Anut, Sawangwit, Utane, Sawatzki, Julia, Schever, Michaela, Schuler, Jacky, Schwab, Cédric, Schweizer, Konstantin, Selyunin, Alexandr, Serafini, Andrea, Settanta, Giulio, Settimo, Mariangela, Sharov, Vladislav, Shaydurova, Arina, Shi, Jingyan, Shi, Yanan, Shutov, Vitaly, Sidorenkov, Andrey, Šimkovic, Fedor, Sirignano, Chiara, Siripak, Jaruchit, Sisti, Monica, Slupecki, Maciej, Smirnov, Mikhail, Smirnov, Oleg, Sogo-Bezerra, Thiago, Sokolov, Sergey, Songwadhana, Julanan, Soonthornthum, Boonrucksar, Sotnikov, Albert, Šrámek, Ondřej, Sreethawong, Warintorn, Stahl, Achim, Stanco, Luca, Stankevich, Konstantin, Štefánik, Dušan, Steiger, Hans, Steinmann, Jochen, Sterr, Tobias, Stock, Matthias Raphael, Strati, Virginia, Studenikin, Alexander, Su, Jun, Sun, Shifeng, Sun, Xilei, Sun, Yongjie, Sun, Yongzhao, Sun, Zhengyang, Suwonjandee, Narumon, Szelezniak, Michal, Takenaka, Akira, Tang, Jian, Tang, Qiang, Tang, Quan, Tang, Xiao, Thara Hariharan, Vidhya, Theisen, Eric, Tietzsch, Alexander, Tkachev, Igor, Tmej, Tomas, Torri, Marco Danilo Claudio, Tortorici, Francesco, Treskov, Konstantin, Triossi, Andrea, Triozzi, Riccardo, Troni, Giancarlo, Trzaska, Wladyslaw, Tung, Yu-Chen, Tuve, Cristina, Ushakov, Nikita, Vedin, Vadim, Verde, Giuseppe, Vialkov, Maxim, Viaud, Benoit, Vollbrecht, Cornelius Moritz, von Sturm, Katharina, Vorobel, Vit, Voronin, Dmitriy, Votano, Lucia, Walker, Pablo, Wang, Caishen, Wang, Chung-Hsiang, Wang, En, Wang, Guoli, Wang, Jian, Wang, Jun, Wang, Lu, Wang, Meng, Wang, Ruiguang, Wang, Siguang, Wang, Wei, Wang, Wenshuai, Wang, Xi, Wang, Xiangyue, Wang, Yangfu, Wang, Yaoguang, Wang, Yi, Wang, Yifang, Wang, Yuanqing, Wang, Zhe, Wang, Zheng, Wang, Zhimin, Watcharangkool, Apimook, Wei, Wei, Wei, Wenlu, Wei, Yadong, Wen, Kaile, Wen, Liangjian, Weng, Jun, Wiebusch, Christopher, Wirth, Rosmarie, Wonsak, Bjoern, Wu, Diru, Wu, Qun, Wu, Zhi, Wurm, Michael, Wurtz, Jacques, Wysotzki, Christian, Xi, Yufei, Xia, Dongmei, Xiao, Xiang, Xie, Xiaochuan, Xie, Yuguang, Xie, Zhangquan, Xin, Zhao, Xing, Zhizhong, Xu, Benda, Xu, Cheng, Xu, Donglian, Xu, Fanrong, Xu, Hangkun, Xu, Jilei, Xu, Jing, Xu, Meihang, Xu, Yin, Xu, Yu, Yan, Baojun, Yan, Qiyu, Yan, Taylor, Yan, Xiongbo, Yan, Yupeng, Yang, Changgen, Yang, Chengfeng, Yang, Jie, Yang, Lei, Yang, Xiaoyu, Yang, Yifan, Yao, Haifeng, Ye, Jiaxuan, Ye, Mei, Ye, Ziping, Yermia, Frédéric, You, Zhengyun, Yu, Boxiang, Yu, Chiye, Yu, Chunxu, Yu, Guojun, Yu, Hongzhao, Yu, Miao, Yu, Xianghui, Yu, Zeyuan, Yu, Zezhong, Yuan, Cenxi, Yuan, Chengzhuo, Yuan, Ying, Yuan, Zhenxiong, Yue, Baobiao, Zafar, Noman, Zavadskyi, Vitalii, Zeng, Shan, Zeng, Tingxuan, Zeng, Yuda, Zhan, Liang, Zhang, Aiqiang, Zhang, Bin, Zhang, Binting, Zhang, Feiyang, Zhang, Haosen, Zhang, Honghao, Zhang, Jialiang, Zhang, Jiawen, Zhang, Jie, Zhang, Jin, Zhang, Jingbo, Zhang, Jinnan, Zhang, Mohan, Zhang, Peng, Zhang, Qingmin, Zhang, Shiqi, Zhang, Shu, Zhang, Shuihan, Zhang, Tao, Zhang, Xiaomei, Zhang, Xin, Zhang, Xuantong, Zhang, Yinhong, Zhang, Yiyu, Zhang, Yongpeng, Zhang, Yu, Zhang, Yuanyuan, Zhang, Yumei, Zhang, Zhenyu, Zhang, Zhijian, Zhao, Jie, Zhao, Rong, Zhao, Runze, Zhao, Shujun, Zheng, Dongqin, Zheng, Hua, Zheng, Yangheng, Zhong, Weirong, Zhou, Jing, Zhou, Li, Zhou, Nan, Zhou, Shun, Zhou, Tong, Zhou, Xiang, Zhu, Jingsen, Zhu, Kangfu, Zhu, Kejun, Zhu, Zhihang, Zhuang, Bo, Zhuang, Honglin, Zong, Liang, Zou, Jiaheng, and Zwickel, Sebastian

Published
2023
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13. IL-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma.

Author

Bick, Fabian, Brenis Gómez, Claudia M., Lammens, Inés, Van Moorleghem, Justine, De Wolf, Caroline, Dupont, Sam, Dumoutier, Laure, Smith, Neal P., Villani, Alexandra-Chloé, Browaeys, Robin, Alladina, Jehan, Haring, Alexis M., Medoff, Benjamin D., Cho, Josalyn L., Bigirimana, René, Vieira, Joao, Hammad, Hamida, Blanchetot, Christophe, Schuijs, Martijn J., and Lambrecht, Bart N.

Abstract

[Display omitted] Asthma is often accompanied by type 2 immunity rich in IL-4, IL-5, and IL-13 cytokines produced by T H 2 lymphocytes or type 2 innate lymphoid cells (ILC2s). IL-2 family cytokines play a key role in the differentiation, homeostasis, and effector function of innate and adaptive lymphocytes. IL-9 and IL-21 boost activation and proliferation of T H 2 and ILC2s, but the relative importance and potential synergism between these γ common chain cytokines are currently unknown. Using newly generated antibodies, we inhibited IL-9 and IL-21 alone or in combination in various murine models of asthma. In a translational approach using segmental allergen challenge, we recently described elevated IL-9 levels in human subjects with allergic asthma compared with nonasthmatic controls. Here, we also measured IL-21 in both groups. IL-9 played a central role in controlling innate IL-33–induced lung inflammation by promoting proliferation and activation of ILC2s in an IL-21–independent manner. Conversely, chronic house dust mite–induced airway inflammation, mainly driven by adaptive immunity, was solely dependent on IL-21, which controlled T H 2 activation, eosinophilia, total serum IgE, and formation of tertiary lymphoid structures. In a model of innate on adaptive immunity driven by papain allergen, a clear synergy was found between both pathways, as combined anti-IL-9 or anti-IL-21 blockade was superior in reducing key asthma features. In human bronchoalveolar lavage samples we measured elevated IL-21 protein within the allergic asthmatic group compared with the allergic control group. We also found increased IL21R transcripts and predicted IL-21 ligand activity in various disease-associated cell subsets. IL-9 and IL-21 play important and nonredundant roles in allergic asthma by boosting ILC2s and T H 2 cells, revealing a dual IL-9 and IL-21 targeting strategy as a new and testable approach. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Search for low-energy neutrinos from astrophysical sources with Borexino

Author

Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cappelli, L., Cavalcante, P., Cavanna, F., Chepurnov, A., Choi, K., D’Angelo, D., Davini, S., Derbin, A., Di Giacinto, A., Di Marcello, V., Ding, X.F., Di Ludovico, A., Di Noto, L., Drachnev, I., Formozov, A., Franco, D., Gabriele, F., Galbiati, C., Gschwender, M., Ghiano, C., Giammarchi, M., Goretti, A., Gromov, M., Guffanti, D., Hagner, C., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kumaran, S., Kobychev, V., Korga, G., Lachenmaier, T., Laubenstein, M., Litvinovich, E., Lombardi, P., Lomskaya, I., Ludhova, L., Lukyanchenko, G., Lukyanchenko, L., Machulin, I., Manuzio, G., Marcocci, S., Maricic, J., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Nieslony, M., Oberauer, L., Orekhov, V., Ortica, F., Pallavicini, M., Papp, L., Penek, Ö., Pietrofaccia, L., Pilipenko, N., Pocar, A., Raikov, G., Ranalli, M.T., Ranucci, G., Razeto, A., Re, A., Redchuk, M., Ricci, B., Romani, A., Rossi, N., Rottenanger, S., Schönert, S., Semenov, D., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Unzhakov, E., Vishneva, A., Vogelaar, R.B., von Feilitzsch, F., Wojcik, M., Wurm, M., Zaimidoroga, O., Zavatarelli, S., Zuber, K., and Zuzel, G.

Published
2021
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21. The association between motor and non-motor symptoms in essential tremor patients being evaluated for deep brain stimulation surgery.

Author

Bishay, Anthony E., Habib, Daniel R.S., Lyons, Alexander T., Hughes, Natasha C., Summers, Jessica E., Dhima, Kaltra, and Bick, Sarah K.

Abstract

• Among ET patients, overall tremor scores were associated with language function. • Elevated Fahn-Tolosa-Marin (FTM) scores correlated with increased severity in depression, language impairment, and visuospatial functioning. • Washington Heights Inwood Genetic Study of Essential Tremor (WHIGET) scores showed no association with any non-motor symptoms. Non-motor symptoms, including depression and cognitive impairment, are common in essential tremor (ET), but associations between these symptoms and tremor are poorly understood. A retrospective, single-institution, cohort study evaluated 140 patients with ET undergoing evaluation for deep brain stimulation (DBS) surgery. The Fahn-Tolosa-Marin (FTM) or Washington Heights-Inwood Genetic Study of ET (WHIGET) scale was used to grade tremor. Tremor scores were divided into quartiles. Patients underwent clinical neuropsychological evaluations that included a comprehensive cognitive test battery and Beck Depression Inventory-II (BDI-II). Subgroup analysis was performed with groups who met criteria for depression (BDI-II > 14) or overall cognitive impairment (<9th percentile on at least two dissimilar cognitive tests). Independent samples t-tests were used for continuous variables and chi square tests for categorical variables. Univariable and multivariable regressions were used to determine relationships between tremor and non-motor scores. Tremor quartile was correlated with language domain performance (p = 0.044) but not depression scores. FTM score was associated with BDI-II (β = 0.940, p = 0.010), language (β = −0.936, p = 0.012), and visuospatial domain (β = −0.836, p = 0.025) scores, such that worse tremor was associated with more depression and worse language and visuospatial function. WHIGET score was not associated with any neuropsychological scores on multivariable regression. FTM score was associated with language, visuospatial, and mood symptoms, suggesting a relationship between the severity of these symptom types. Different tremor scores capture different motor symptoms and relationships with nonmotor symptoms. [ABSTRACT FROM AUTHOR]

Published
2024
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23. The Monte Carlo simulation of the Borexino detector

Author

Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bagdasarian, Z., Basilico, D., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Borodikhina, L., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Canepa, M., Caprioli, S., Carlini, M., Cavalcante, P., Chepurnov, A., Choi, K., D’Angelo, D., Davini, S., Derbin, A., Ding, X.F., Di Noto, L., Drachnev, I., Fomenko, K., Formozov, A., Franco, D., Froborg, F., Gabriele, F., Galbiati, C., Ghiano, C., Giammarchi, M., Goeger-Neff, M., Goretti, A., Gromov, M., Hagner, C., Houdy, T., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korablev, D., Korga, G., Kryn, D., Laubenstein, M., Litvinovich, E., Lombardi, F., Lombardi, P., Ludhova, L., Lukyanchenko, G., Machulin, I., Magnozzi, M., Manuzio, G., Marcocci, S., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Muratova, V., Neumair, B., Oberauer, L., Opitz, B., Ortica, F., Pallavicini, M., Papp, L., Pocar, A., Ranucci, G., Razeto, A., Re, A., Romani, A., Roncin, R., Rossi, N., Schönert, S., Semenov, D., Shakina, P., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Stokes, L.F.F., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Toropova, M., Unzhakov, E., Vishneva, A., Vogelaar, R.B., von Feilitzsch, F., Wang, H., Weinz, S., Wojcik, M., Wurm, M., Yokley, Z., Zaimidoroga, O., Zavatarelli, S., Zuber, K., and Zuzel, G.

Published
2018
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24. Seasonal modulation of the 7Be solar neutrino rate in Borexino

Author

Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Basilico, D., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Borodikhina, L., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Caprioli, S., Carlini, M., Cavalcante, P., Chepurnov, A., Choi, K., D’Angelo, D., Davini, S., Derbin, A., Ding, X.F., Di Noto, L., Drachnev, I., Fomenko, K., Franco, D., Froborg, F., Gabriele, F., Galbiati, C., Ghiano, C., Giammarchi, M., Goeger-Neff, M., Goretti, A., Gromov, M., Hagner, C., Houdy, T., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Jany, A., Jeschke, D., Kobychev, V., Korablev, D., Korga, G., Kryn, D., Laubenstein, M., Lehnert, B., Litvinovich, E., Lombardi, F., Lombardi, P., Ludhova, L., Lukyanchenko, G., Machulin, I., Manecki, S., Manuzio, G., Marcocci, S., Martyn, J., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Montuschi, M., Muratova, V., Neumair, B., Oberauer, L., Opitz, B., Ortica, F., Pallavicini, M., Papp, L., Pocar, A., Ranucci, G., Razeto, A., Re, A., Romani, A., Roncin, R., Rossi, N., Schönert, S., Semenov, D., Shakina, P., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Stokes, L.F.F., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Toropova, M., Unzhakov, E., Vishneva, A., Vogelaar, R.B., von Feilitzsch, F., Wang, H., Weinz, S., Wojcik, M., Wurm, M., Yokley, Z., Zaimidoroga, O., Zavatarelli, S., Zuber, K., and Zuzel, G.

Published
2017
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27. Borexino’s search for low-energy neutrino and antineutrino signals correlated with gamma-ray bursts

Author

Agostini, M., Altenmüller, K., Appel, S., Atroshchenko, V., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Carlini, M., Cavalcante, P., Chepurnov, A., Choi, K., D’Angelo, D., Davini, S., de Kerret, H., Derbin, A., Di Noto, L., Drachnev, I., Etenko, A., Fomenko, K., Franco, D., Gabriele, F., Galbiati, C., Ghiano, C., Giammarchi, M., Goeger-Neff, M., Goretti, A., Gromov, M., Hagner, C., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Jany, A., Jedrzejczak, K., Jeschke, D., Kobychev, V., Korablev, D., Korga, G., Kryn, D., Laubenstein, M., Lehnert, B., Litvinovich, E., Lombardi, F., Lombardi, P., Ludhova, L., Lukyanchenko, G., Machulin, I., Manecki, S., Maneschg, W., Manuzio, G., Marcocci, S., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Montuschi, M., Mosteiro, P., Muratova, V., Neumair, B., Oberauer, L., Obolensky, M., Ortica, F., Pallavicini, M., Papp, L., Pocar, A., Ranucci, G., Razeto, A., Re, A., Romani, A., Roncin, R., Rossi, N., Schönert, S., Semenov, D., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Sukhotin, S., Suvorov, Y., Tartaglia, R., Testera, G., Thurn, J., Toropova, M., Unzhakov, E., Vishneva, A., Vogelaar, R.B., von Feilitzsch, F., Wang, H., Weinz, S., Winter, J., Wojcik, M., Wurm, M., Yokley, Z., Zaimidoroga, O., Zavatarelli, S., Zuber, K., and Zuzel, G.

Published
2017
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30. SOX: Short Distance Neutrino Oscillations with Borexino

Author

Agostini, M., Althenmüller, K., Bellini, G., Benziger, J., Berton, N., Bick, D., Bonfini, G., Caccianiga, B., Cadonati, L., Calaprice, F., Caminata, A., Cavalcante, P., Chavarria, A., Chepurnov, A., Cribier, M., D'Angelo, D., Davini, S., Derbin, A., di Noto, L., Durero, M., Empl, A., Etenko, A., Farinon, S., Fischer, V., Fomenko, K., Franco, D., Gabriele, F., Gaffiot, J., Galbiati, C., Gazzana, S., Ghiano, C., Giammarchi, M., Göger-Neff, M., Goretti, A., Grandi, L., Gromov, M., Hagner, C., Houdy, Th., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Jonquères, N., Kobychev, V., Korablev, D., Korga, G., Kryn, D., Lasserre, T., Laubenstein, M., Lehnert, B., Lewke, T., Link, J., Litvinovich, E., Lombardi, F., Lombardi, P., Ludhova, L., Lukyanchenko, G., Machulin, I., Manecki, S., Maneschg, W., Marcocci, S., Maricic, J., Meindl, Q., Mention, G., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Montuschi, M., Mosteiro, P., Muratova, V., Musenich, R., Oberauer, L., Obolensky, M., Ortica, F., Otis, K., Pallavicini, M., Papp, L., Perasso, L., Pocar, A., Ranucci, G., Razeto, A., Re, A., Romani, A., Rossi, N., Saldanha, R., Salvo, C., Schönert, S., Scola, L., Simgen, H., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Sukhotin, S., Suvorov, Y., Tartaglia, R., Testera, G., Veyssière, C., Vivier, M., Vogelaar, R.B., von Feilitzsch, F., Wang, H., Winter, J., Wojcik, M., Wright, A., Wurm, M., Zaimidoroga, O., Zavatarelli, S., Zuber, K., Zuzel, G., and Bravo-Berguño, D.

Published
2016
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31. Recent results from Borexino and the first real time measure of solar pp neutrinos

Author

Zavatarelli, S., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Bravo, D., Caccianiga, B., Cadonati, L., Calaprice, F., Caminata, A., Cavalcante, P., Chavarria, A., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Empl, A., Etenko, A., Fomenko, K., Franco, D., Gabriele, F., Galbiati, C., Gazzana, S., Ghiano, C., Giammarchi, M., Göger-Neff, M., Goretti, A., Gromov, M., Hagner, C., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Kobychev, V., Korablev, D., Korga, G., Kryn, D., Laubenstein, M., Lehnert, B., Lewke, T., Litvinovich, E., Lombardi, F., Lombardi, P., Ludhova, L., Lukyanchenko, G., Machulin, I., Manecki, S., Maneschg, W., Marcocci, S., Meindl, Q., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Montuschi, M., Mosteiro, P., Muratova, V., Oberauer, L., Obolensky, M., Ortica, F., Otis, K., Pallavicini, M., Papp, L., Perasso, L., Pocar, A., Ranucci, G., Razeto, A., Re, A., Romani, A., Rossi, N., Saldanha, R., Salvo, C., Schönert, S., Simgen, H., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Sukhotin, S., Suvorov, Y., Tartaglia, R., Testera, G., Vignaud, D., Vogelaar, R.B., von Feilitzsch, F., Wang, H., Winter, J., Wojcik, M., Wright, A., Wurm, M., Zaimidoroga, O., Zuber, K., and Zuzel, G.

Published
2016
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34. FDX1 regulates cellular protein lipoylation through direct binding to LIAS.

Author

Dreishpoon, Margaret B., Bick, Nolan R., Petrova, Boryana, Warui, Douglas M., Cameron, Alison, Booker, Squire J., Kanarek, Naama, Golub, Todd R., and Tsvetkov, Peter

Subjects
*CARRIER proteins, *IRON clusters, *CELL respiration, *FERREDOXINS, *ELECTRON donors, *PROTEINS, *POST-translational modification
Abstract

erredoxins are a family of iron–sulfur (Fe-S) cluster proteins that serve as essential electron donors in numerous cellular processes that are conserved through evolution. The promiscuous nature of ferredoxins as electron donors enables them to participate in many metabolic processes including steroid, heme, vitamin D, and Fe-S cluster biosynthesis in different organisms. However, the unique natural function(s) of each of the two human ferredoxins (FDX1 and FDX2) are still poorly characterized. We recently reported that FDX1 is both a crucial regulator of copper ionophore-induced cell death and serves as an upstream regulator of cellular protein lipoylation, a mitochondrial lipid-based post-translational modification naturally occurring on four mitochondrial enzymes that are crucial for TCA cycle function. Here we show that FDX1 directly regulates protein lipoylation by binding the lipoyl synthase (LIAS) enzyme promoting its functional binding to the lipoyl carrier protein GCSH and not through indirect regulation of cellular Fe-S cluster biosynthesis. Metabolite profiling revealed that the predominant cellular metabolic outcome of FDX1 loss of function is manifested through the regulation of the four lipoylation-dependent enzymes ultimately resulting in loss of cellular respiration and sensitivity to mild glucose starvation. Transcriptional profiling established that FDX1 loss-of-function results in the induction of both compensatory metabolism-related genes and the integrated stress response, consistent with our findings that FDX1 loss-of-function is conditionally lethal. Together, our findings establish that FDX1 directly engages with LIAS, promoting its role in cellular protein lipoylation, a process essential in main)taining cell viability under low glucose conditions. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Structural brain differences in essential tremor and Parkinson's disease deep brain stimulation patients.

Author

Franco, Giulia, Trujillo, Paula, Lopez, Alexander M., Aumann, Megan A., Englot, Dario J., Hainline, Allison, Kang, Hakmook, Konrad, Peter E., Dawant, Benoit M., Claassen, Daniel O., and Bick, Sarah K.

Abstract

[Display omitted] • We used quantified cortical thickness and subcortical volumes and performed regression to identify areas associated with ET or PD. • Smaller volumes in pallidum and thalamus were associated with greater odds of ET diagnosis. • Reduced thicknesses in anterior orbital gyrus, lateral orbital gyrus, and medial precentral gyrus were associated with ET. • Reduced volumes in caudate, amygdala, putamen, and basal forebrain were associated with PD. • Reduced thickness in pars orbitalis, supramarginal gyrus, and posterior cingulate were associated with PD. Essential tremor (ET) and Parkinson's disease (PD) are the most common tremor disorders and are common indications for deep brain stimulation (DBS). In some patients, PD and ET symptoms overlap and diagnosis can be challenging based on clinical criteria alone. The objective of this study was to identify structural brain differences between PD and ET DBS patients to help differentiate these disorders and improve our understanding of the different brain regions involved in these pathologic processes. We included ET and PD patients scheduled to undergo DBS surgery in this observational study. Patients underwent 3T brain MRI while under general anesthesia as part of their procedure. Cortical thicknesses and subcortical volumes were quantified from T1-weighted images using automated multi-atlas segmentation. We used logistic regression analysis to identify brain regions associated with diagnosis of ET or PD. 149 ET and 265 PD patients were included. Smaller volumes in the pallidum and thalamus and reduced thickness in the anterior orbital gyrus, lateral orbital gyrus, and medial precentral gyrus were associated with greater odds of ET diagnosis. Conversely, reduced volumes in the caudate, amygdala, putamen, and basal forebrain, and reduced thickness in the orbital part of the inferior frontal gyrus, supramarginal gyrus, and posterior cingulate were associated with greater odds of PD diagnosis. These findings identify structural brain differences between PD and ET patients. These results expand our understanding of the different brain regions involved in these disorders and suggest that structural MRI may help to differentiate patients with these two disorders. [ABSTRACT FROM AUTHOR]

Published
2023
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36. A longitudinal qualitative study of women's experiences of postnatal care following hypertensive disorders of pregnancy.

Author

Silverio, Sergio A., Bye, Amanda, Hildersley, Rosanna, Chingara, Olivia, Chang, Yan-Shing, and Bick, Debra

Abstract

There has been little focus on women's views of care and recovery following pregnancy complicated by hypertensive disorders of pregnancy [HDP] despite long-term implications for maternal health. Increasingly in clinical research, areas of interest include the extent to which women are involved in postnatal care planning, perceived value of routine postnatal contacts, lifestyle behaviour advice, and extent to which ongoing concerns about HDP could be discussed with healthcare professionals. This study explored women's experiences of birth-recovery up to 12 months following HDP. A longitudinal qualitative study using semi-structured interviews at four and 12 months postpartum. Twenty-four women who each had a form of HDP, were recruited using a maximum variation, purposive sampling strategy from four National Health Service maternity units in London, 21 of whom were interviewed at both time points. Data were collected and analysed by timepoint following a recurrent, cross-sectional cohort approach using template analysis methodology. Four main themes and ten sub-themes were identified. Main themes included: assumptions about blood pressure; perinatal experiences; postnatal care pathways; and managing complex health conditions. Postnatal care needs to be tailored to women's individual needs following HDP, with ongoing review by relevant clinicians during and beyond the first six weeks. Many women with HDP have ongoing information needs about hypertensive status, treatment and prognoses, and future birth planning. Policy makers, health providers and funders cannot continue to ignore the need to ensure postnatal services meet the needs of women who have experienced medically complex pregnancies. [ABSTRACT FROM AUTHOR]

Published
2023
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37. Low-energy (anti)neutrino physics with Borexino: Neutrinos from the primary proton-proton fusion process in the Sun

Author

Mosteiro, P., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Bravo, D., Caccianiga, B., Cadonati, L., Calaprice, F., Caminata, A., Cavalcante, P., Chavarría, Á., Chepurnov, A., D'Angelo, D., Davini, S., Derbin, A., Empl, A., Etenko, A., Fomenko, K., Franco, D., Gabriele, F., Galbiati, C., Gazzana, S., Ghiano, C., Giammarchi, M., Göger-Neff, M., Goretti, A., Gromov, M., Hagner, C., Hungerford, E., Ianni, Al., Ianni, An., Kobychev, V., Korablëv, D., Korga, G., Kryn, D., Laubenstein, M., Lehnert, B., Lewke, T., Litvinovich, E., Lombardi, F., Lombardi, P., Ludhova, L., Lukyanchenko, G., Machulin, I., Manecki, S., Maneschg, W., Marcocci, S., Meindl, Q., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Montuschi, M., Muratova, V., Oberauer, L., Obolensky, M., Ortica, F., Otis, K., Pallavicini, M., Papp, L., Perasso, L., Pocar, A., Ranucci, G., Razeto, A., Re, A., Romani, A., Rossi, N., Saldanha, R., Salvo, C., Schönert, S., Simgen, H., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Sukhotin, S., Suvorov, Y., Tartaglia, R., Testera, G., Vignaud, D., Vogelaar, R.B., von Feilitzsch, F., Wang, H., Winter, J., Wojcik, M., Wright, A., Wurm, M., Zaimidoroga, O., Zavatarelli, S., Zuber, K., and Zuzel, G.

Published
2015
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38. Short Distance Neutrino Oscillations with BoreXino: SOX

Author

Smirnov, O., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Bravo, D., Caccianiga, B., Calaprice, F., Caminata, A., Cavalcante, P., Chavarria, A., Chepurnov, A., D’Angelo, D., Davini, S., Derbin, A., Empl, A., Etenko, A., Fomenko, K., Franco, D., Galbiati, C., Gazzana, S., Ghiano, C., Giammarchi, M., Göger-Neff, M., Goretti, A., Hagner, C., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Kobychev, V., Korablev, D., Korga, G., Kryn, D., Laubenstein, M., Lehnert, B., Lewke, T., Litvinovich, E., Lombardi, P., Lombardi, F., Ludhova, L., Lukyanchenko, G., Machulin, I., Manecki, S., Maneschg, W., Marcocci, S., Meindl, Q., Meroni, E., Meyer, M., Miramonti, L., Misiaszek, M., Mosteiro, P., Muratova, V., Oberauer, L., Obolensky, M., Ortica, F., Otis, K., Pallavicini, M., Papp, L., Perasso, L., Pocar, A., Ranucci, G., Razeto, A., Re, A., Romani, A., Rossi, N., Saldanha, R., Salvo, C., Schönert, S., Simgen, H., Skorokhvatov, M., Sotnikov, A., Sukhotin, S., Suvorov, Y., Tartaglia, R., Testera, G., Vignaud, D., Vogelaar, R.B., von Feilitzsch, F., Wang, H., Winter, J., Wojcik, M., Wright, A., Wurm, M., Zaimidoroga, O., Zavatarelli, S., Zuber, K., and Zuzel, G.

Published
2015
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40. Low-energy Neutrino Astronomy in LENA

Author

Wurm, M., Bick, D., Enqvist, T., Hellgartner, D., Kaiser, M., Loo, K.K., Lorenz, S., Meloni, M., Meyer, M., Möllenberg, R., Oberauer, L., Soiron, M., Smirnov, M., Trzaska, W.H., and Wonsak, B.

Published
2015
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41. Geo-neutrinos from 1353 Days with the Borexino Detector

Author

Miramonti, L., Bellini, G., Benziger, J., Bick, D., Bonfini, G., Bravo, D., Avanzini, M. Buizza, Caccianiga, B., Cadonati, L., Calaprice, F., Cavalcante, P., Chavarria, A., Chepurnov, A., D’Angelo, D., Davini, S., Derbin, A., Empl, A., Etenko, A., Fiorentini, G., Fomenko, K., Franco, D., Galbiati, C., Gazzana, S., Ghiano, C., Giammarchi, M., Goeger-Neff, M., Goretti, A., Grandi, L., Hagner, C., Hungerford, E., Ianni, Aldo, Ianni, Andrea, Kobychev, V.V., Korablev, D., Korga, G., Koshio, Y., Kryn, D., Laubenstein, M., Lewke, T., Litvinovich, E., Loer, B., Lombardi, P., Lombardi, F., Ludhova, L., Lukyanchenko, G., Machulin, I., Manecki, S., Maneschg, W., Mantovani, F., Manuzio, G., Meindl, Q., Meroni, E., Misiaszek, M., Mosteiro, P., Muratova, V., Oberauer, L., Obolensky, M., Ortica, F., Otis, K., Pallavicini, M., Papp, L., Perasso, L., Perasso, S., Pocar, A., Ranucci, G., Razeto, A., Re, A., Ricci, B., Romani, A., Rossi, N., Sabelnikov, A., Saldanha, R., Salvo, C., Schönert, S., Simgen, H., Skorokhvatov, M., Smirnov, O., Sotnikov, A., Sukhotin, S., Suvorov, Y., Tartaglia, R., Testera, G., Vignaud, D., Vogelaar, R.B., von Feilitzsch, F., Winter, J., Wojcik, M., Wright, A., Wurm, M., Xu, J., Zaimidoroga, O., Zavatarelli, S., and Zuzel, G.

Published
2015
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42. Modulus simulation of asphalt binder models using Molecular Dynamics (MD) method

Author

Yao, Hui, Dai, Qingli, You, Zhanping, Bick, Andreas, and Wang, Min

Subjects
Simulation -- Analysis, Molecular dynamics -- Methods -- Usage, Binders (Materials) -- Research -- Properties, Business, Construction and materials industries
Abstract

ABSTRACT The objectives of this study are, 1) to simulate asphalt binder modified with exfoliated multi-layered graphite nanoplatelets (xGNP) using the Molecular Dynamics (MD) method, and 2) to analyze different [...]

Published
2018
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