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Abstract: Fungal endocarditis is rare but potentially a lethal condition. Large bulky vegetations are common and can present as peripheral thromboembolism. We report a case of a 73-year-old man who had an uneventful aortic valve replacement and coronary artery bypass grafting. He was readmitted with embolic occlusion of lower limb vessels. This was treated with embolectomy. Investigations suggested a ‘thrombus’ in the ascending aorta, which during surgery revealed itself to be aspergillosis. Obtaining a histopathology of the removed embolus is often omitted in cases of embolic occlusion of lower limb arteries as the source is nearly always a thrombus. Uncommonly, infective endocarditis can be the source of peripheral embolism and hence histopathology and microbiology of the embolus should be obtained if it appears different as the prognosis is better if treated early and aggressively. [Copyright &y& Elsevier]

Mucuna , a treasured leguminous genus is renowned for its high L-DOPA (L-3, 4-dihydroxyphenylalanine) content which acts as an effective anti-Parkinson's drug. Unfortunately, the immense medicinal properties of most Mucuna (M.) species are still remained unnoticed. Thus, in present study we have explored and compared various properties of neglected M. bracteata and M. imbricata from India with frequently consumed Mucuna pruriens var. utilis and commercialized Mucuca powder. The aqueous extracts of all these Mucuna samples were assessed for its nutritional, anti-nutritional, secondary metabolites and pharmacologically active principle (L-dopa) elements employing specific techniques. HPLC analysis in present investigation reveals that M. bracteata contains highest L-DOPA (7.61 ± 0.11%) than other studied spp. which verifies its efficacy to be used against Parkinson's disease. The total antioxidant capacity of the methanol extract of M. bracteata was higher which can be interconnected with its higher total phenolic content (8.76 ± 0.20%). It also has maximum nutritional values such as total ash, dietary fiber and starch. Moreover, M. imbricata another overlooked Mucuna spp. also showed maximum gross energy, total moisture and total carbohydrates with effective anti-inflammatory property (59.25 ± 0.03%). Thus, present results proves the potential of M. imbricata and M. bracteata as a natural active alternative source of L-DOPA with promising medicinal properties supportive in developing anti-Parkinson's drug in future. • Comparative study of market procured Mucuna with neglected and underutilized Mucuna species. • Treasure out the best solvent system for Antioxidant potential and substitute for Mucuna spp. • Both exhibited optimum level of proximate composition and essential secondary metabolites. • Both unnoticed Mucuna spp. showed reasonable level of L-dopa an anti-Parkinson's drug. • Thus can serve as alternative for designing pharmaceuticals in PD remedy. [ABSTRACT FROM AUTHOR]