1. Bariatric Surgery and Solid-Organ Transplantation.
- Author
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García Ruiz de Gordejuela, Amador, Ibarzabal, Ainitze, and Osorio, Javier
- Subjects
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TRANSPLANTATION of organs, tissues, etc. , *BARIATRIC surgery , *KIDNEY transplantation , *NON-alcoholic fatty liver disease , *HEART transplantation , *LIVER transplantation , *LUNG transplantation - Abstract
• Morbid obesity and its comorbidities negatively influence both transplant candidates and transplant recipients. • Bariatric surgery may be a conduit for solid-organ transplant in patients with morbid obesity with end-staged solid-organ disease. • Bariatric surgery may prevent some patients from requiring liver transplant and may favor transplant in cases of obesity. • Bariatric surgery is feasible before, during, and after liver transplant. • Bariatric surgery is related to better results in kidney transplant, with less primary graft dysfunction and better graft survival. • Bariatric surgery also may improve results in cardiac and lung transplant candidates. Morbid obesity and being overweight are a growing problem worldwide. They also affect patients with end-stage solid-organ disease and patients after transplant. Bariatric surgery is the most effective available weight loss procedure. Bariatric surgery can be helpful for the treatment of some conditions, such as nonalcoholic fatty liver disease or nonalcoholic steatohepatitis, which may lead to transplant, and weight loss can improve or even reverse them. In other cases, morbid obesity is a limitation to accessing a transplant program, so bariatric surgery can serve as a conduit to transplant. After transplant, obesity and obesity-related comorbidities can be a significant health problem that may be treated, as in patients without a transplant, with bariatric surgery. There are some specific conditions and issues to be considered in patients with end-stage solid-organ disease who are candidates for bariatric surgery, such as increased morbidity and mortality. After transplant, immunosuppressant regimens and technical limitations may be also significant. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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