1. Colonization of neonate skin by Malassezia species: Relationship with neonatal cephalic pustulosis.
- Author
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Ayhan, Meltem, Sancak, Banu, Karaduman, Ayşen, Arıkan, Sevtap, and Şahin, Sedef
- Subjects
FUNGI ,YEAST ,DERMATOLOGY ,INFANT diseases - Abstract
Background: Colonization of neonate skin by Malassezia species and their causative role in neonatal cephalic pustulosis is unclear. Objectives: We sought to determine the skin colonization by Malassezia in healthy newborns, and to investigate its association with neonatal cephalic pustulosis. Methods: Samples for Malassezia colonization were taken from cheeks and scalps of 104 neonates between 24 and 72 hours after birth, and again 2 or 4 weeks later. Pustules were sampled with concomitant nonlesional skin cultures if neonatal cephalic pustulosis was diagnosed. Results: Malassezia colonization increased significantly with age of the neonate (5% at the first week, 30% at 2-4 weeks). In all, 26 patients were given the diagnosis of neonatal cephalic pustulosis during follow-up. No correlation was found between the severity of the disease and Malassezia isolation. Skin colonization of patients with neonatal cephalic pustulosis (20.8%) was not higher than colonization of healthy newborns (37%). Limitations: Not all of the neonates were examined by the authors at the second visit. Conclusions: Malassezia colonization increases after the first week of life. No correlation was found between neonatal cephalic pustulosis and Malassezia. [Copyright &y& Elsevier]
- Published
- 2007
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