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Your search keyword '"Ye, Jiantao"' showing total 2 results
Start Over Author "Ye, Jiantao" Topic heart cells Publisher elsevier b.v.
2 results on '"Ye, Jiantao"'

1. COX-2 is involved in ET-1-induced hypertrophy of neonatal rat cardiomyocytes: Role of NFATc3.

Author

Li, Hong, Gao, Si, Ye, Jiantao, Feng, Xiaojun, Cai, Yi, Liu, Zhiping, Lu, Jing, Li, Qin, Huang, Xiaoyang, Chen, Shaorui, and Liu, Peiqing

Subjects
*CYCLOOXYGENASE 2 inhibitors, *GENETIC regulation of enzymes, *HYPERTROPHY, *HEART cells, *RNA interference, *PROSTAGLANDINS, *NF-kappa B
Abstract

Highlights: [•] In cardiomyocytes, ET-1 treatment resulted in significant upregulation of COX-2 expression and activity. [•] Both COX-2 inhibitors and COX-2 RNA interference suppressed cardiomyocyte hypertrophy induced by ET-1. [•] Calcineurin/NFATc3 signaling pathway participated in the transcriptional regulation of COX-2 by ET-1. [ABSTRACT FROM AUTHOR]

Published
2014
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2. C/EBPβ knockdown protects cardiomyocytes from hypertrophy via inhibition of p65-NFκB.

Author

Zou, Jian, Li, Hong, Chen, Xi, Zeng, Siyu, Ye, Jiantao, Zhou, Changhua, Liu, Min, Zhang, Luankun, Yu, Na, Gan, Xiaohong, Zhou, Houfeng, Xian, Zhiwei, Chen, Shaorui, and Liu, Peiqing

Subjects
*HEART cells, *HYPERTROPHY, *NF-kappa B, *ENZYME inhibitors, *IN vitro studies, *CHROMOSOMAL translocation, *DNA-binding proteins
Abstract

Highlights: [•] C/EBPβ expression is upregulated in response to hypertrophic stimulation in vitro and in vivo. [•] C/EBPβ knockdown protects cardiomyocytes from hypertrophy. [•] C/EBPβ knockdown reduced the nuclear translocation of p65-NFκB, and diminished NFκB-DNA binding activity. [ABSTRACT FROM AUTHOR]

Published
2014
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