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• COVID-19 images were analyzed with a new preprocessing model. • In this study, feature extraction was performed from COVID-19 images according to RGB values. • The proposed model was tested by statistical methods. • The results of both normal data and feature-reduced data were compared. The COVID-19 pandemic spread all over the world, starting in China in late 2019, and significantly affected life in all aspects. As seen in SARS, MERS, COVID-19 outbreaks, coronaviruses pose a great threat to world health. The COVID-19 epidemic, which caused pandemics all over the world, continues to seriously threaten people's lives. Due to the rapid spread of COVID-19, many countries' healthcare sectors were caught off guard. This situation put a burden on doctors and healthcare professionals that they could not handle. All of the studies on COVID-19 in the literature have been done to help experts to recognize COVID-19 more accurately, to use more accurate diagnosis and appropriate treatment methods. The alleviation of this workload will be possible by developing computer aided early and accurate diagnosis systems with machine learning. Diagnosis and evaluation of pneumonia on computed tomography images provide significant benefits in investigating possible complications and in case follow-up. Pneumonia and lesions occurring in the lungs should be carefully examined as it helps in the diagnostic process during the pandemic period. For this reason, the first diagnosis and medications are very important to prevent the disease from progressing. In this study, a dataset consisting of Pneumonia and Normal images was used by proposing a new image preprocessing process. These preprocessed images were reduced to 15x15 unit size and their features were extracted according to their RGB values. Experimental studies were carried out by performing both normal values and feature reduction among these features. RGB values of the images were used in train and test processes for MLAs. In experimental studies, 5 different Machine Learning Algorithms (MLAs) (Multi Class Support Vector Machine (MC-SVM), k Nearest Neighbor (k-NN), Decision Tree (DT), Multinominal Logistic Regression (MLR), Naive Bayes (NB)). The following accuracy rates were obtained in train operations for MLAs, respectively; 1, 1, 1, 0.746377, 0.963768. Accuracy results in test operations were obtained as follows; 0.87755, 0.857143, 0.857143, 0.877551, 0.938776. [ABSTRACT FROM AUTHOR]

The new type of coronavirus, COVID 19, appeared in China at the end of 2019. It has become a pandemic that is spreading all over the world in a very short time. The detection of this disease, which has serious health and socio-economic damages, is of vital importance. COVID-19 detection is performed by applying PCR and serological tests. Additionally, COVID detection is possible using X-ray and computed tomography images. Disease detection has an important position in scientific researches that includes artificial intelligence methods. The combined models, which consist of different phases, are frequently used for classification problems. In this paper, a new combined approach is proposed to detect COVID-19 cases using deep features obtained from X-ray images. Two main variances of the approach can be presented as single layer-based (SLB) and feature fusion-based (FFB). SLB model consists of pre-processing, deep feature extraction, post-processing, and classification phases. On the other side, the FFB model consists of pre-processing, deep feature extraction, feature fusion, post-processing, and classification phases. Four different SLB and six different FFB models were developed according to the number and binary combination of layers used in the feature extraction phase. Each model is employed for binary and multi-class classification experiments. According to experimental results, the accuracy performance for COVID-19 and no-findings classification of the proposed FFB3 model is 99.52%, which is better than the best performance accuracy (of 98.08%) in the literature. Concurrently, for multi-class classification, the proposed FFB3 model has an accuracy performance of 87.64% outperforming the best existing work (which reported an 87.02% classification performance). Various metrics, including sensitivity, specificity, precision, and F1-score metrics are used for performance analysis. For all performance metrics, the FFB3 model recorded a higher success rate than existing work in the literature. To the best of our knowledge, these accuracy rates are the best in the literature for the dataset and data split type (five-fold cross-validation). Composite models (SLBs and FFBs), which are generated in this paper, are successful ways to detect COVID-19. Experimental results show that feature extraction, pre-processing, post-processing, and hyperparameter tuning are the steps are necessary to obtain a higher success. For prospective works, different types of pre-trained models and other hyperparameter tuning methods can be implemented. • Using pre-trained CNN models is an effective way to extract deep features • Feature fusion-based model is more successful to detect COVID-19 in X-Ray images • Data pre-processing and post-processing techniques increase the performance of the models • Hyperparameter tuned SVM is more successful than without one • To the best of our knowledge, obtained accuracy rates are the best in the literature [ABSTRACT FROM AUTHOR]

The 2019 novel coronavirus (COVID-19) originating from China, has spread rapidly among people living in other countries. According to the World Health Organization (WHO), by the end of January, more than 104 million people have been affected by COVID-19, including more than 2 million deaths. The number of COVID-19 test kits available in hospitals is reduced due to the increase in regular cases. Therefore, an automatic detection system should be introduced as a fast, alternative diagnostic to prevent COVID-19 from spreading among humans. For this purpose, three different BiT models: DenseNet, InceptionV3, and Inception-ResNetV4 have been proposed in this analysis for the diagnosis of patients infected with coronavirus pneumonia using X-ray radiographs in the chest. These three models give and examine Receiver Operating Characteristic (ROC) analyses and uncertainty matrices, using 5-fold cross-validation. We have performed the simulations which have visualized that the pre-trained DenseNet model has the best classification efficiency with 92% among two other models proposed (83.47% accuracy for inception V3 and 85.57% accuracy for Inception-ResNetV4). • COVID-19 prediction using chest X-ray images. • The manual method i.e. PCR is time-consuming and high costs. • A novel automated image-based technique DenseNet and BiTModels like R101x1, which segment and identify Covid-19 patient x-ray. • Covid-19 normal and affected patient data is used. • Comparing with other models, training and testing accuracy, the R101x1 has an average accuracy, i.e., 91% in the Covid-19 class Prediction. [ABSTRACT FROM AUTHOR]

• A deep learning COVID-19 diagnostic system is developed using state-of-the-art deep learning architectures. • A detailed analysis of different methods used for detecting COVID-19 is presented in this paper. • Chest X-rays from different sources are collected to build a robust classification model. • The developed diagnostic model provided efficient results, even with a limited number of input images. • The results produced in this work are validated by an expert radiologist. In recent months, a novel virus named Coronavirus has emerged to become a pandemic. The virus is spreading not only humans, but it is also affecting animals. First ever case of Coronavirus was registered in city of Wuhan, Hubei province of China on 31st of December in 2019. Coronavirus infected patients display very similar symptoms like pneumonia, and it attacks the respiratory organs of the body, causing difficulty in breathing. The disease is diagnosed using a Real-Time Reverse Transcriptase Polymerase Chain reaction (RT-PCR) kit and requires time in the laboratory to confirm the presence of the virus. Due to insufficient availability of the kits, the suspected patients cannot be treated in time, which in turn increases the chance of spreading the disease. To overcome this solution, radiologists observed the changes appearing in the radiological images such as X-ray and CT scans. Using deep learning algorithms, the suspected patients' X-ray or Computed Tomography (CT) scan can differentiate between the healthy person and the patient affected by Coronavirus. In this paper, popular deep learning architectures are used to develop a Coronavirus diagnostic systems. The architectures used in this paper are VGG16, DenseNet121, Xception, NASNet, and EfficientNet. Multiclass classification is performed in this paper. The classes considered are COVID-19 positive patients, normal patients, and other class. In other class, chest X-ray images of pneumonia, influenza, and other illnesses related to the chest region are included. The accuracies obtained for VGG16, DenseNet121, Xception, NASNet, and EfficientNet are 79.01%, 89.96%, 88.03%, 85.03% and 93.48% respectively. The need for deep learning with radiologic images is necessary for this critical condition as this will provide a second opinion to the radiologists fast and accurately. These deep learning Coronavirus detection systems can also be useful in the regions where expert physicians and well-equipped clinics are not easily accessible. [ABSTRACT FROM AUTHOR]