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A simple and efficient method for the synthesis of highly functionalized furo[3,2- c ]coumarins was developed. The reaction occurred via initial formation of biscoumarins from the reaction of 4-hydroxycoumarins and aldehydes/aryl methyl ketones in the presence of molecular iodine in DMSO followed by lactone ring opening, cyclization and oxidative aromatization process. The reaction conditions were moderate, work-up procedure was simple and products were obtained in high yield. [ABSTRACT FROM AUTHOR]

Abstract: Some novel spiro substituted pyrido[2,3-c]coumarin derivatives were synthesized from 4-hydroxycoumarin by exploring ‘tertiary amino effect’ reaction strategy. [Copyright &y& Elsevier]

Abstract: Some novel functionalized dihydropyrido[2,3-d]pyrimidine derivatives 4 were synthesized using a one-pot three-component reaction of 6-aminouracils 1, aryl aldehydes 2 and 3-cyanoacetyl indole 3 using InCl3 as catalyst. [Copyright &y& Elsevier]