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Start Over Topic alkaloids Region changbai mountains (china & korea) Publisher elsevier b.v.
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1. Isolation and identification of antibacterial neo-compounds from the red ants of ChangBai Mountain, Tetramorium sp.

Author

Song, Zheng-Wei, Liu, Pu, Yin, Wei-Ping, Jiang, Ya-Ling, and Ren, Yun-lai

Subjects
*TETRAMORIUM, *ANIMAL extracts, *ALKALOIDS, *THERAPEUTIC use of coumarins, *ANTIBACTERIAL agents, *STRUCTURE-activity relationship in pharmacology
Abstract

Abstract: Three novel coumarin compounds along with two known amide alkaloids were isolated from a methanol extract of the red ants of ChangBai Mountain, Tetramorium sp. Their structures were identified on the basis of IR, 2D NMR (1H–1H COSY, HSQC, HMBC and NOESY) and HRESIMS analysis. Antibacterial activity of all the compounds was evaluated using KB paper diffusion through measurement of inhibiting zone. It was found that four of all the compounds exhibited significant inhibitory activity against Gram-positive bacteria Bacillus subtilis with MIC values of 25μg/ml (compounds 1–3) and 15μg/ml (compound 4). [Copyright &y& Elsevier]

Published
2012
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