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Introduction: Elbow stiffness is an uncommon condition that significantly impacting a patient's daily activities. Trauma is the most frequent cause of elbow stiffness. However, capitellum fractures are rare, accounting for approximately 1 % of elbow fractures. They are often misdiagnosed due to nonspecific symptoms and the complex anatomy of the elbow joint., Case Presentation: We report the case of a 54-year-old female who presented with left elbow stiffness eight months after a traumatic incident. On physical examination, her left elbow extension was +10°, and flexion was restricted to 65°, with no limitation in pronation or supination. Imaging studies revealed a malunited capitellum with osteophytes at the posterolateral site of the olecranon. A 3D-printed model of her elbow was created based on a CT scan to aid surgical planning. She underwent capsulectomy and osteotomy and was stabilized with two bioabsorbable P(L/DL)LA pins. Six months postoperatively, the patient's elbow range of motion was fully restored, and no complications were observed., Clinical Discussion: Elbow stiffness resulting from the malunion of a capitellum fracture typically necessitates surgical intervention to restore functional movement in the elbow., Conclusion: Capitellum fractures are uncommon and frequently underdiagnosed, leading to complications such as elbow stiffness and reduced functionality. Early detection is crucial, as delayed diagnosis can result in complex management due to malunion. 3D printing from CT scans helps surgeons accurately evaluate malunions and plan precise surgical interventions., Competing Interests: Conflict of interest None., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Introduction: The incidence of anaplastic transformation of thyroid cancer from Papillary Thyroid Carcinoma (PTC) is a rare tumor event, which ranges from 1 to 2 % of all cases of thyroid malignancy. Anaplastic transformation is often reported in primary lesions, but is rarely found in metastatic lesions from Differentiated Thyroid Carcinoma (DTC)., Presentation of Case: This case report reports a unique tumor process where a 70-year-old woman had a metastatic lesion in the Mandible from PTC which transformed into ATC with histological features resembling squamous cell carcinoma-type. Immunohistochemical examination was able to prove that the lesion in the Mandible is a type of undifferentiated Thyroid carcinoma (anaplastic) with a squamous pattern originating from PTC., Discussion: This type of tumor with histological variant images that resemble other types of tumors is a challenge for diagnosis and appropriate management, so understanding the variants of this type of ATC is important for better management., Conclusion: Although rare, anaplastic transformation can occur in metastatic sites of PTC. This necessitates the need for early accurate diagnosis through IHC assessment and somatic mutation testing so that appropriate treatment can be delivered., Competing Interests: Conflict of interest statement The authors declare no conflict of interests., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Introduction and Importance: The cervical spine is a dynamic structure that protects adjacent nervous innervation and maintains the range of motion (ROM) of the head and neck. Fractures in this area can lead to high mortality and morbidity, with bone fractures accounting for 56 % of cervical spinal cord injuries. This case series presents a series of cervical pathologies treated with posterior decompression and stabilization using laminar and lateral mass screw fixation., Methods: This research is a case series of four patients treated with laminar and lateral mass screw technique. All patients received a surgical procedure, including posterior compression and stabilization, which included the use of a laminar and lateral mass screw. We followed the patient for 12 months. During follow up, outcome measures consisting of VAS, range of motion, neurological status, ODI Score, SF-12 Score and any complications related to the surgical procedure was recorded and calculated every 3 months., Outcomes: This series examines four distinct cases. The initial case pertained to a female patient, aged 72, who exhibited tetraparesis resulting from a burst fracture occurring in the C3-C5 vertebrae. The underlying etiology of this pathology is considered to be mineral bone disease associated with thyroid hormone imbalance due to thyroid cancer. The second instance was a 14-year-old child experiencing neck pain due to spondylitis tuberculosis in the C1-C2 region, accompanied by a retropharyngeal abscess and occipitocervical dissociation (OCD) with basilar invagination. The third example pertained to a patient who is 9 years old and presented with weakness in all extremities due to C1 fracture-dislocation. The fourth case was a 14-year-old patient who experienced a fall from a bunk bed. This patient was diagnosed with Traumatic Atlantoaxial dislocation with odontoid fracture Type II. All patients showed improved cervical curvature and range of motion with the advantages of reduction of intraoperative haemorrhage, as well as a decrease in postoperative rehabilitation duration. Overall, the data shows a general trend of improvement in VAS and ODI scores over time, with SF-12 scores stabilizing or slightly decreasing by 12 months post-operation., Conclusion: The use of a lateral mass screw for subaxial cervical injuries can be employed to manage cervical spine pathologies like fractures and infections, including spondylitis TB. However, more research is required to evaluate the long-term complications and success rates of this technique., Competing Interests: Conflict of interest statement The authors have no financial or proprietary interests in any material discussed in this manuscript., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Introduction and Importance: Zygomaticomaxillary (ZMC) fractures are common, often resulting from traffic accidents, and account for 17 % of facial fractures. These fractures can lead to issues such as enophthalmos, flattened cheeks, diplopia, maxillary hypoesthesia. If the reduction is inadequate to restore facial structure, long term-functional and aesthetic complications may arise. In such cases a computed tomography (CT) scan with 3-dimensional (3D) reconstruction is valuable to assessing the fracture and planning surgery, with current technological advancements, 3D printing can now be utilized for this purpose., Presentation of Case: A 24-year-old male, after a motorcycle accident and initial surgery for maxillofacial fractures, experienced persistent diplopia and facial numbness. Physical examination showed malpositioning of the right eye, and a CT scan with 3D reconstruction revealed multiple fractures and prior internal fixation. A 3D-printed model was created to plan a second surgery using rib cartilage and a silicone orbital base for orbital rim reconstruction. Post-surgery, the patient reported minimal pain and no diplopia or blurred vision in the primary gaze position., Clinical Discussions: 3D printing is beneficial in facial reconstruction, aiding in surgical planning by allowing precise measurement and design of graft. Rib cartilage can serve as an alternative for orbital rim reconstruction, and 3D printing facilitates accurate harvesting of the rib., Conclusion: In cases of severe ZMC fracture, 3D printing was utilized as a guide during surgical preparation to achieve improved outcomes., Competing Interests: Conflict of interest statement All authors report no conflicts of interest. This study did not receive any financial or not-financial support., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

In the previous report, we reported that Hypomontagnella monticulosa originating from the rhizome of Zingiber griffithii was known to produce a marine-derived natural product. An OSMAC-based approach was designed by modifying the nutritional composition of the growth medium to investigate any possible new metabolites produced by the strain. The culture filtrate and biomass were conditioned through the use of three basal media, namely, Czapek-dox, potato dextrose, and Wickerham broth medium. GC-MS and multivariate analysis was performed to distinguish the chemicals and determine their composition in the tested extracts. Antimicrobial activity was tested against selected human pathogenic microbes using the disk-diffusion method. The MeOH extract of both culture filtrate and biomass from different fermentation media revealed that the majority of identified compounds ( n = 40) were found in Wickerham medium ( n = 23), which is later termed as MeOH-Wi. The chemical composition of MeOH-Wi was fatty acids (21.74 %), followed by terpenoids (17.38 %), cyclosiloxane (13.04 %), aldehydes (13.04 %), alkenes (8.7 %), hydrocarbons (8.7 %), esters (8.7 %), alkaloids (4.35 %), and an unclassified compound, the 9,9-Dimethyl-3,7-diazabicyclo[3.3.1]nonane. The numerous chemical compounds in MeOH-Wi corresponded with its antimicrobial activities against Micrococcus luteus NBRC 13,867 (±11 mm), Candida maltosa NBRC 1977 (±9 mm), and Escherichia coli JM 109 (±5 mm) which were higher than the other tested extracts. Further purification using HPLC RP-C 18 using NP-SiO 2 / n -Hex-EtOAc (10:2) to yield compound (1) . Compound (1) was determined as an analog of briarian W-a diterpene mostly found in marine sponge, Briareum spp.-as a pure compound in the MeOH extract of H. monticulosa based on the 1D and 2D NMR analysis. The anticancer activity (IC 50 ) of compound (1) was 0.077, 0.080, and 0.102 µg/mL against the growth of HCT-116, NBT-T2, and Panc-1, respectively. As far as we are aware, this is the first report on finding a briarian diterpene that originates from an endophytic fungus, especially by H. monticulosa., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors. Published by Elsevier B.V.)

Soil-transmitted helminth (STH) is a part of NTDs that remains to be eliminated because of its significant global impact. Diagnostics are essential in aiding the elimination of STH infection. Therefore, it is imperative to evaluate the progress of diagnostic techniques, especially molecular-based techniques. Nevertheless, there is currently no comprehensive systematic review and meta-analysis (SRMA) evaluating the performance of molecular-based techniques for diagnosing STH. This protocol, registered on PROSPERO (CRD42024563432), intends to assess the diagnostic accuracy of molecular-based techniques compared to microscopic-based techniques for four common STH infections ( A. lumbricoides, T. trichiura , hookworms, and S. stercoralis ) across global studies. Two authors will independently conduct the screening, study selection, data extraction, and quality assessment of this SRMA. The obtained studies will be assessed using QUADAS-2 and will be analyzed for publication bias and diagnostic accuracy, including sensitivity, specificity, NPV, PPV, and DOR, and SROC. This developed protocol is expected to be versatile enough to be implemented in the range of studies assessing the diagnostic accuracy of the advance compared to the convention methods with adjustments. The findings of this SRMA are expected to provide a valuable contribution towards achieving the goal of eradicating STH infection by 2030., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors.)

Introduction and Importance: Slipped capital femoral epiphysis (SCFE) is one of the most common hip pathology in adolescents. Outcome of SCFE management largely depends on the grading of the pathology. Severe, unstable SCFE poses high risk for avascular necrosis (AVN). The objective of this study is to report a good outcome without AVN in an acute, unstable, high grade SCFE managed by closed reduction and percutaneous pinning along with factors that need to be given consideration., Case Presentation: A 13 years old boy was unable to bear weight due to severe pain on right hip after trauma since 2 weeks. Patient was diagnosed with acute, unstable high grade SCFE, patient underwent closed reduction and percutaneous pinning (CRPP) using cannulated screw and K wire augmented with spica cast. At 12 weeks patient was already fully active. At 18 month follow up there was no sign of AVN with full hip range of movement., Clinical Discussion: Treatment for unstable, severe SCFE is still challenging. Unreduced severe slippage will deliver serious impingement and end up with early degenerative arthritis. The magnitude of reduction in a severe, unstable SCFE poses high risk for AVN. While some studies claimed reduction is justified only when it is serendipitous, we successfully and purposely performed CRPP., Conclusion: Even after 2 weeks from onset, an acute and severe slippage can still be reduced closely and fixed percutaneously. The hip regain full range of motion with no sign of AVN on x ray at 18 months follow up., Competing Interests: Conflict of interest statement The authors certify that They have NO affiliations with or involvement in any organization or entity with any financial interest or non-financial interest in the subject matter or materials discussed in this manuscript., (Copyright © 2024. Published by Elsevier Ltd.)

Introduction: Medial Patellofemoral ligament (MPFL) reconstruction, the primary procedure for restoring patellar stability and preventing further dislocation, has seen numerous methods and grafts. However, a consensus on the technique and graft remains elusive. This study introduces a novel approach to MPFL reconstruction, utilizing a unique combination of minimal invasiveness, de novo method, and arthroscopic guidance to harvest a quadriceps tendon (QT) graft without the need for a harvesting tool., Case Illustration: A 37-year-old female presented to the emergency room with the chief complaints of left knee pain and swelling following the third spontaneous dislocation of the patella. The patient had a few episodes of locking sensation and instability of the left knee while walking, especially while climbing stairs. A knee MRI revealed MPFL tear in the left knee. A modified minimal invasive MPFL reconstruction technique was performed. The IKDC, Lysholm, and Modified Cincinnati scores improved significantly from preoperatively 48.3 %, 49 %, and 51 % to 89.7 %, 90 %, and 95 % consecutively. No recurrent patellar dislocations or swelling were reported during follow-up., Discussion: While quadriceps graft harvesting for MPFL reconstruction is typically highly invasive, using quadriceps tendons has consistently shown excellent outcomes. This study, however, takes it a step further by demonstrating that a minimally invasive procedure for harvesting quadriceps tendons, even without specialized instrumentation, can also yield excellent results., Conclusion: MPFL reconstruction using superficial quadriceps tendon autograft can be achieved using a minimally invasive technique without the use of specialized instrumentation and has shown excellent knee functional improvement., Competing Interests: Conflict of interest statement The authors have no conflict of interest to report., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Introduction: Gout is an inflammatory arthritis that causes acute pain due to the accumulation of uric acid crystals. Hyperuricemia primarily causes it, resulting in the deposition of monosodium urate crystals in and around joints. Gout can affect joints such as the metatarsophalangeal joint and the foot's talus bone. Treatment involves addressing hyperuricemia and managing symptoms with medications like febuxostat. Surgical treatment is crucial, especially in cases of chronic tophaceous gout or severe joint damage, including arthroscopic debridement, ankle arthrodesis, or total ankle arthroplasty., Case Presentation: A 32-year-old male with a history of hyperuricemia experienced pain in his left ankle for a year. The ankle was swollen and prone to pain when he walked. Magnetic resonance imaging (MRI) tests revealed the thickening and irregular shape of the anterior talofibular ligament (ATFL), suggesting a rupture. The arthroscopic operation revealed a crystal deposit, leading to the diagnosis of gout arthritis and subsequent debridement for the patient. Following the surgery, the patient experienced minimal pain, an improved range of motion, and a significant improvement in swelling within a week. The patient was able to walk with minimal assistance and without aid., Discussion: Gout arthritis and ATFL injuries share common clinical features, including joint swelling, limited motion, and joint deformity. The presence of monosodium urate (MSU) crystals and inflammation in both conditions complicates diagnosis. Performing arthroscopic debridement surgery in gout arthritis presents challenges due to tophi and inflammation, as well as the risk of articular cartilage damage. Expertise is crucial for successful arthroscopic debridement, with patient selection, preoperative planning, and thorough removal of MSU crystals being key factors., Conclusion: Thorough evaluation, patient selection, preoperative planning, joint identification, removal of MSU crystals, and comprehensive postoperative care are crucial for successful arthroscopic debridement for gout arthritis of the ankle., Competing Interests: Conflict of interest statement Not applicable., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Introduction: Breast cancer is the most common cancer in women and a leading cause of mortality. This systematic review and meta-analysis aims to evaluate the correlation between breast density measurements obtained from various software and visual assessments by radiologists using full-field digital mammography (FFDM)., Methods: Following the PRISMA 2020 guidelines, five databases (Pubmed, Google Scholar, Science Direct, Cochrane Library, and MEDLINE) were searched for studies correlating volumetric breast density with breast cancer risk. The Newcastle-Ottawa Scale and the Joanna Briggs Institute Checklist were used to assess the quality of the included studies. Meta-analysis of correlation was applied to aggregate correlation coefficients using a random-effects model using MedCalc Statistical Software version 19.2.6., Results: The review included 22 studies with a total of 58,491 women. The pooled correlation coefficient for volumetric breast density amongst Volpara™ and Quantra™ was found to be 0.755 (95% CI 0.496-0.890, p < 0.001), indicating a high positive correlation, albeit with a significant heterogeneity (I 2  = 99.89%, p < 0.0001). Subgroup analyses based on study origin, quality, and methodology were performed but did not reveal the heterogeneity cause. Egger's and Begg's tests showed no significant publication bias., Conclusion: Volumetric breast density is strongly correlated with breast cancer risk, underscoring the importance of accurate breast density assessment in screening programs. Automated volumetric measurement tools like Volpara™ and Quantra™ provide reliable assessments, potentially improving breast cancer risk prediction and management., Implications for Practice: Implementing fully automated breast density assessment tools could enhance consistency in clinical practice, minimizing observer variability and improving screening accuracy. These tools should be further validated against standardized criteria to ensure reliability in diverse clinical settings., (Copyright © 2024 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.)

Introduction and Importance: Blunt abdominal trauma can result in various injuries, including intestinal hematomas causing obstruction. Traumatic submucosal jejunal hematomas are rare, especially in children, with bicycle handlebar injuries being a potential cause. Prompt recognition and appropriate imaging are crucial for accurate diagnosis and management., Case Presentation: A 10-year-old boy presented with delayed abdominal pain, vomiting, and absence of bowel movements following blunt abdominal trauma from a bicycle handlebar injury. Abdominal CT scan confirmed a submucosal jejunal hematoma, leading to exploratory laparotomy and duodenojejunostomy., Clinical Discussion: Bicycle handlebar injuries, although seemingly minor, can cause significant internal damage, especially in children. Delayed symptoms pose a diagnostic challenge, necessitating a high index of suspicion and imaging modalities like CT scans for timely intervention., Conclusion: This case underscores the importance of considering traumatic submucosal jejunal hematomas in children with blunt abdominal trauma, particularly from bicycle handlebar injuries. Surgical intervention may be necessary in cases of complete intestinal obstruction, emphasizing the need for prompt diagnosis and treatment., Competing Interests: Declaration of competing interest All authors have no conflicts of interest to declare., (Copyright © 2024. Published by Elsevier Ltd.)

Introduction and Importance: Long-term friction of the FHL tendon's sheath (caused by sporting activities) can result in tendinitis, which causes pain in the foot and ankle and consequently interferes with everyday life and foot function. The FHL tendon is crucial for maintaining foot stability and can be damaged by overuse. FHL tendinitis can be also caused by inflammatory tendon sheath filled. Arthroscopy can play a role in the diagnosis and treatment of this condition., Case Presentation: A 28-year-old female with left ankle pain was brought to our clinic after slipping on a train platform nine months ago. X-rays and MR imaging revealed a complete tear of the ATFL, minimal joint effusion, and a bony protrusion causing impingement. Arthroscopic surgery was performed, and the patient's pain sensation improved to 0-1 in the visual analogue scale (VAS) within three weeks. The Foot and Ankle Ability Measure (FAAM) score increased from 8 % to 100 %, and the patient was able to walk and perform daily activities normally., Clinical Discussion: The FHL tendon sheath begins at the posterior tubercles of the talus and forms a fibroosseous tunnel along the medial calcaneus, potentially leading to impingement during ankle or hallux dorsiflexion. FHL tendon impingement and tendinitis share clinical manifestations, and if conservative treatments (NSAIDs, physical therapy) fail after 6 months, arthroscopic surgery is recommended for its minimally invasive benefits. Both arthroscopic and open surgical techniques yield positive outcomes for FHL pathologies; however, they carry risks such as neurovascular complications, highlighting the necessity for surgical precision and expertise., Conclusion: We concluded that in this case, FHL impingement was caused by the bony protrusion from Stieda process fragment. It was demonstrated that the arthroscopic surgery with loose body removal was successful and practical., Competing Interests: Conflict of interest statement The authors have no conflict interest or proprietary interests in any material discussed in this manuscript., (Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)

Unsupervised classification using vegetation indices has been extensively employed to map mangrove forests using medium-resolution satellite images. However, its capability is restricted to determining the extent of mangroves only. This study introduces a new spectral index called the enhanced mangrove index (EMI) for accurately mapping different components of mangrove vegetation, including mangrove trees, nypa, and understorey. An immediate effort is required to monitor the invasion of nypa and understorey in the mangrove forest of Segara Anakan Lagoon, located in Central Java, Indonesia. This issue may also be prevalent in other mangrove areas worldwide. The development of EMI involved: 1). the analysis of the reflectance exhibited by different types of mangrove vegetation, and 2). The performance of EMI was evaluated by comparing it with spectral indices such as automated mangrove map and index (AMMI), as well as supervised classification models like random forest (RF). The accuracy assessment indicates that the overall accuracy and Kappa coefficient achieved values of 0.87 and 0.84, respectively, surpassing other spectral indices and supervised classification models. AMMI and RF exhibited high overall accuracy, with values of 0.82 and 0.73, respectively. Additionally, they demonstrated a Kappa coefficient of 0.77 and 0.66, respectively., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Authors.)

This paper introduces a comprehensive dataset focusing on the surface roughness and dimensional accuracy of 3D printed specimens derived from a hybrid manufacturing process. The design of these specimens incorporates surfaces oriented at 0˚, 45˚, and 90˚ angles for surface roughness testing, along with cylindrical, radial, and pocket areas to evaluate dimensional accuracy. Utilizing PLA material, the specimens undergo a printing phase followed by milling within the same machine, thereby enhancing both surface roughness and dimensional quality. Surface roughness data is gathered through a surface roughness tester, while dimensional accuracy is assessed using a digital vernier caliper. The dataset includes comparative analyses conducted before and after the hybrid manufacturing process, revealing notable improvements in both surface roughness and dimensional accuracy post-processing. These findings furnish valuable insights for researchers and engineers engaged in hybrid manufacturing processes involving PLA material, serving as a foundational resource for further investigations and advancements in the field., (© 2024 The Author(s).)

Given the importance of securitization markets as an alternative access to finance MSMEs, understanding bank-level MSME loan securitization issuance is essential to help shed light on the situation. This paper describes a novel dataset of 440 securitized MSME loan deals of 48 European originators covering the period between 2004 and 2022. Information regarding the originators are hand-collected by reading the prospectus filed. The ready-to-use dataset comprises four main categories: 1) bank stability measures, 2) mediator variables consisting of funding cost, regulatory capital, risk and liquidity, 3) MSME loan securitization issuances, and 4) control variables at the macro and institutional level. Further, this paper aims at providing the step-by-step technique of how to hand-collect information regarding collateral in place. The final dataset is valuable for economic and finance researchers to explore factors related to MSME loan securitization and bank stability in Europe., (© 2024 The Author(s).)

Legundi Island, located in Lampung Bay, Indonesia, has high solar energy potential but still relies on Diesel Power Plants. This research aims to design a hybrid Solar Power Plant and Diesel Power plant system that is environmentally friendly and reliable. Analysis was conducted using the Homer software. •This research designs a hybrid Solar Power Plant system with a capacity of 170.2 kWp and a battery of 1,036 kWh, integrated with three existing Diesel Power Plants units with a capacity of 200 kW.•This system can generate electricity of 296,391 kWh/year with a renewable energy fraction reaching 79.9% and an electricity surplus of 0.988%.•Fuel consumption decreased by 79.3% compared to the existing Diesel Power Plant system., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Author(s).)

The top 20 highest burdened countries (in disability-adjusted life years) account for more than 75% of the global burden of viral hepatitis. An effective response in these 20 countries is crucial if global elimination targets are to be achieved. In this update of the Lancet Gastroenterology & Hepatology Commission on accelerating the elimination of viral hepatitis, we convene national experts from each of the top 20 highest burdened countries to provide an update on progress. Although the global burden of diseases is falling, progress towards elimination varies greatly by country. By use of a hepatitis elimination policy index conceived as part of the 2019 Commission, we measure countries' progress towards elimination. Progress in elimination policy has been made in 14 of 20 countries with the highest burden since 2018, with the most substantial gains observed in Bangladesh, India, Indonesia, Japan, and Russia. Most improvements are attributable to the publication of formalised national action plans for the elimination of viral hepatitis, provision of publicly funded screening programmes, and government subsidisation of antiviral treatments. Key themes that emerged from discussion between national commissioners from the highest burdened countries build on the original recommendations to accelerate the global elimination of viral hepatitis. These themes include the need for simplified models of care, improved access to appropriate diagnostics, financing initiatives, and rapid implementation of lessons from the COVID-19 pandemic., Competing Interests: Declaration of interests GSC is supported in part by the Biomedical Research Centre of Imperial College NHS Trust. In the last 36 months, IW has received grant funding from AbbVie, Arena, AstraZeneca, Novartis, and Pharco. JG has received funding from AbbVie, bioLytical, Camurus, Cepheid, Gilead, Hologic, and Indivior. YT has received funding from Fujirebio, Sysmex, AbbVie, GlaxoSmithKline, and Gilead Sciences. JVL acknowledges grants and speaker fees from AbbVie, Gilead Sciences, Merck Sharp and Dohme, and Roche Diagnostics to his institution; speaker fees from Echosens, Janssen, Novo Nordisk, and ViiV; consulting fees from GSK and Novavax; and support to ISGlobal (grant CEX2018-000806-S) funded by MCIN/AEI/10.13039/501100011033, and the Generalitat de Catalunya through the CERCA programme, outside of the submitted work. DLT has provided expert testimony for Merck; has worked on diagnostics with Abbott. Through the Taskforce for Global Health, LH and JWW have received support for the Coalition for Global Hepatitis Elimination from governmental, philanthropic, individual, and industry partners (Abbott Laboratories, AbbVie, Cepheid, Gilead Sciences, Merck, Pharco, Roche Diagnostics, Siemens, VBI Vaccines, and Zydus-Cadila). DA-P has received payment from Viatris and Inogen Pharmaceutical for delivering presentations at conferences. ADM received AU$300 in 2021 to review a grant for the National Medical Research Council, Singapore. HC received lecture fees from Gilead Sciences. A portion of MAD's compensation comes from the Bill & Melinda Gates Foundation Global Public Goods Grant through its funding of work done for the Global Burden of Diseases, Injuries & Risk Factors study. All other authors declare no competing interests., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Streptococcus pneumoniae is the leading cause of bacterial pneumonia, bacteremia, and meningitis. Indonesia introduced the pneumococcal conjugate vaccine (PCV) nationwide in 2022. In this study, we present whole genome sequence (WGS) data of 94 S. pneumoniae isolates that were obtained from hospitalized patients, healthy children, and adult groups from different regions prior to PCV program in Indonesia. DNA sequences of S. pneumoniae were obtained using the TruSeq Nano DNA kit (Illumina NovaSeq6000 Platform). The genome data of S. pneumoniae features a 1,969,562 bp to 2,741,371 bp circular chromosome with 39-40% G+C content. The genome includes 1935-3319 coding sequences (CDS), 2 to 5 rRNA genes, 43 to 49 tRNA genes, and 56 to 71 ncRNA. These data will be useful for analyzing the serotype, sequence type, virulence genes, antimicrobial resistance genes, and the impact of pneumococcal vaccination in Indonesia. The FASTQ raw files of these sequences are available under BioProject accession number PRJNA995903 and Sequence Read Archive accession numbers SRR25316461-SRR25316554., (© 2024 The Authors.)

This dataset contains data from a survey of officers in correctional institutions throughout Indonesia. A total of 1284 officers completed the survey regarding their self-assessment of proactive work behavior, perceived organizational support, person-environment fit, proactive personality, and role breadth self-efficacy. In addition to raw data, this dataset presents the characteristics of respondents, a description of respondents' answers, and statistical validation of this survey data. This dataset can be reused by researchers for the evaluation of factors that encourage proactive behavior in the correctional context. In addition, this dataset can be utilized by policy makers related to human resource management in correctional institutions in Indonesia., (© 2024 The Author(s).)

Knowing the level of SARS-CoV-2 transmission is crucial for decision-making on Coronavirus disease (COVID-19) handling. Guidelines for measuring SARS-CoV-2 antibodies to estimate seroprevalence are conceptually straightforward and internationally available. However, challenges exist for developing countries with limited laboratory capacity, diverse geographical topography, fragmented health information systems and limited resources such as Indonesia. One year after the first case was confirmed in Indonesia, approximately ten infections were undiagnosed or underreported for every reported case. Under those circumstances, we described the method and lessons learned in conducting nationwide cohort COVID-19 serology surveys in a nation with limited resources, such as Indonesia. •Strong cross-sectoral collaboration between ministries and levels of governance (central and subnational) enables strategic use of civil registration database for efficient sampling.•All agglomeration districts (highly dense population and urban area) were selected as study sites, and additional non-agglomeration districts were selected using probability-proportional-to-size (PPS).•Involving the experienced phlebotomist in community health service provider and district laboratory cut down preparation time., Competing Interests: The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: One of the authors is affiliated with the funding organization. While the development of the manuscript did not entail direct involvement from the funders during its preparation, the publication of the manuscript is subject to approval by the funding organization., (© 2024 The Authors. Published by Elsevier B.V.)

This paper presents a dataset of load-displacement obtained from shear loading tests on pure GFRP laminates and hybrid GFRP-graphite filler laminates. The specimens were cut according to the ASTM D 7078 standard, and the width and thickness of the notch area were measured at least three times. Shear loading was applied at a rate of 2 mm/min, and data were recorded from unloading until specimen failure. The data provides information on the maximum load and unique behavior of GFRP laminates. Based on the obtained load, the shear stress (MPa) unit can be calculated. This data can serve as a basis for researchers and engineers working with GFRP laminates and hybrid GFRP-graphite filler laminates., (© 2024 The Author(s).)

The COVID-19 outbreak led higher education institutions to shift to distance learning. This article describes data on the self-regulation of undergraduate students in online and blended learning environments during the pandemic situation. A total of 577 students including 144 males and 433 females in Jakarta were recruited using a combination of purposive and snowball techniques. In this non-experimental voluntary survey design, the questionnaire designed by Barnard et al. [1] was adapted to collect data. The online survey was utilized to gather data on personal demographic information (15 items), goal setting (5 items), time management (3 items), environment structuring (4 items), help-seeking (4 items), task strategies (4 items), and self-evaluation (4 items). It was carried out during May and June 2023. The data were analyzed using frequency distributions and correlation analysis. The raw data is available in Excel format. The collected data offer new insights regarding students' self-regulated online learning in terms of gender, academic year, age, daily internet usage, and more. The dataset will guide education policymakers on the role of self-regulatory skills for the success of technology-enhanced learning and educators to design educational programs to increase students' academic performance in online and blended learning contexts., Competing Interests: The author declares that he has no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Author(s).)

Few studies have investigated the mucosal immune response after BNT162b2-booster vaccination in individuals with periodontitis. In this study, we evaluated the persistence of IgA anti-SARS-CoV-2-N-protein in saliva and gingival crevicular fluid (GCF) of patients with periodontitis for at least six months post BNT162b2 vaccine booster. We included patients with moderate (n = 7) and severe (n = 7) periodontitis and participants without periodontitis (n = 7) as controls. The Bradford method measured the protein concentrations in the samples, and an enzyme-linked immunosorbent assay of the SARS-CoV-2 N protein was performed to analyze the targeted IgA level. For the tested SARS-CoV-2 antigen (N-protein), IgA levels in saliva and GCF showed a strong and significant correlation. Therefore, in patients with moderate or severe periodontitis, saliva and GCF can provide information regarding the IgA response against SARS-CoV-2-N-protein. The neutralizing activity of IgA against SARS-CoV-2 was not investigated in this study, necessitating further research., (© 2023 Association for Dental Sciences of the Republic of China. Publishing services by Elsevier B.V.)

This dataset is part of fundamental research to produce IoT monitoring in fishponds. The data consists of the results of measurements of pH, total dissolved solids (TDS), and water temperature obtained through manual sensor devices in several locations at different times. Additionally, this data also includes images taken by drones at consistent heights. These images are linked to the sensor data that has been collected. In this research, data will be used to monitor the health of fishponds through visual data. This data can be used for correlation analysis between visual data and sensor data. The hypothesis is the visual appearance of the pond (the colour) is affected by the number of mixed solid (mud and other organic material) in the water, which reflected in the TDS level of the water. In addition, the data can also be used for initial investigations into the development of machine learning models for pool condition recognition through image analysis., (© 2023 The Authors.)

The tourism industry has currently grown in various aspects, including the types of attractions, their quantity, and the number of tourist visits in various regions, contributing positively to both regional and global economies. Historical transactions are essential for developing recommender systems, utilizing techniques such as Collaborative Filtering and Demographic Filtering. TripAdvisor is a reputable website providing a wide range of accessible tourism information, including attractions, user profiles, and ratings. However, this unstructured raw data requires processing to create an adequate dataset for recommender systems. This study conducted a series of data processing steps on the raw data, including data restructuring, validation, content addition, integration with Google Maps, normalization, and modeling. This study successfully produced an original dataset comprising User Transaction, Item or Attraction, Attraction Type, Continent, Region, Country, City, and Visiting Mode. It also includes an entity relational model for tourism in Indonesia, particularly in Bali, Malang, and Yogyakarta regions, based on various global user experiences. This dataset is adequate and essential for developing various models of tourism recommender systems such as using Collaborative Filtering., (© 2023 The Author(s).)

This study aims to automatically analyze and extract abnormalities in the lung field due to Coronavirus Disease 2019 (COVID-19). Types of abnormalities that can be detected are Ground Glass Opacity (GGO) and consolidation. The proposed method can also identify the location of the abnormality in the lung field, that is, the central and peripheral lung area. The location and type of these abnormalities affect the severity and confidence level of a patient suffering from COVID-19. The detection results using the proposed method are compared with the results of manual detection by radiologists. From the experimental results, the proposed system can provide an average error of 0.059 for the severity score and 0.069 for the confidence level. This method has been implemented in a web-based application for general users.•A method to detect the appearance of viral pneumonia imaging features, namely Ground Glass Opacity (GGO) and consolidation on the chest Computed Tomography (CT) scan images.•This method can separate the lung field to the right lung and the left lung, and it also can identify the detected imaging feature's location in the central or peripheral of the lung field.•Severity level and confidence level of the patient's suffering are measured., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Author(s).)

Potatoes are of the utmost importance for both food processing and daily consumption; however, they are also prone to pests and diseases, which can cause significant economic losses. To address this issue, the implementation of image processing and computer vision methods in conjunction with machine learning and deep learning techniques can serve as an alternative approach for quickly identifying diseases in potato leaves. Several studies have demonstrated promising results. However, the current research is limited by the use of a single dataset, the PlantVillage dataset, which may not accurately represent the diverse conditions of potato pests and diseases in real-world settings. Therefore, a new dataset that accurately depicts various types of diseases is crucial. We propose a novel dataset that offers several advantages over previous datasets, including data obtained in an uncontrolled environment that results in a diverse range of variables such as background and image angles. The proposed dataset comprises 3076 images categorized into seven classes, including leaves attacked by viruses, bacteria, fungi, pests, nematodes, phytophthora, and healthy leaves. This dataset aims to provide a more accurate representation of potato leaf diseases and facilitate advancements in the current research on potato leaf disease identification., (© 2023 The Author(s).)

In recent years, biodiversity has emerged as a prominent and pressing topic due to the urgent need to address biodiversity loss and the recognition of its connections to climate change and sustainable development. Additionally, increased public awareness and the consideration of economic factors have further underscored the significance of biodiversity conservation. To investigate the sentiment of the Indonesian people towards biodiversity, we conducted a comprehensive data collection on Twitter, focusing on keywords we have set. We amassed a substantial dataset of 500,000 Indonesian tweets from January 2020 to March 2023. These tweets encompassed a wide range of discussions on biodiversity, including its subdomains such as food security, health, and environmental management. Three annotators labeled each tweet with a sentiment class (positive, negative, neutral), or label none for unrelated tweet. The final label was determined using the majority voting method. The tweets with the final label none and those with undecided sentiment class were considered invalid and excluded in the subsequent process. Before labeling, a team of 18 experts jointly developed a labeling guide. This document served as a reference in labeling. After going through a series of processes, including cleaning (removing duplications, irrelevant tweets, and tweets written other than in Indonesian) and preprocessing, we prepared a dataset containing 13,435 tweets. We measured the inter-annotator agreement level, made several models using different algorithms and the K-Fold cross-validation method, and evaluated the models. The Fleiss' Kappa value of the dataset was 0.62187 as the value of the inter-annotator agreement level, and the F1-score value with the best model using the pre-trained IndoBERT model was 0.7959. The Fleiss' Kappa and F1-score values suggest that the annotators have a substantial comprehension and agreement of how to label a tweet, thus ensuring consistency and reliability of our dataset, and the reusability of our dataset is quite suitable for further research on sentiment analysis on biodiversity, respectively. This dataset will benefit various research, including topic modeling, sentiment analysis, public opinion analysis on Twitter, etc., especially biodiversity-related policies., (© 2023 The Author(s).)

The systematic review and meta-analysis were conducted for COVID-19 infections in kidney transplant patients. Recent research on this topic was still scarce and limited meta-analysis research discussion, specific to some risks or treatment in kidney transplantation patients with COVID-19 infection. Therefore, this article demonstrated the fundamental steps to conducting systematic review and meta-analysis studies to derive a pooled estimate of predictor factors of worse outcomes in kidney transplant patients with positive for the SARS-CoV- 2 test•PICOT Framework to determine the research scope•PRISMA strategy for study selection•Forest Plot for meta-analysis study., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Author(s).)

Introduction: The pedunculated fibroid is classically managed through vaginal myomectomy. However, vaginal myomectomy cannot be safely and easily performed in all cases. We reviewed three cases of prolapsed pedunculated submucosal fibroids, each with a specific surgical difficulty., Presentation of Cases: The first case had a prolapsed pedunculated uterine fibroid in pregnancy and underwent fibroid extirpation during an emergency cesarean section through the lower uterine segment incision. The second case was a nulliparous woman with recurrent abnormal uterine bleeding due to a giant prolapsed pedunculated uterine fibroid who underwent laparotomy fibroid extirpation through posterior colpotomy, preserving the uterus. The third case had a prolapsed pedunculated uterine fibroid in perimenopause with multiple fibroids and underwent fibroid stalk excision through an isthmic incision to facilitate a safe laparotomy hysterectomy procedure., Discussion: Vaginal removal has become the standard surgical method for prolapsed pedunculated submucous fibroids. However, some possible consequences of vaginal myomectomy include severe stalk bleeding, infection, and uterus inversion induced by excessive traction. Therefore, specific approaches are needed in some circumstances., Conclusion: Customised surgical approaches provided safe and efficient access to the prolapsed pedunculated fibroid stalk during myomectomy or hysterectomy., Competing Interests: Conflict of interest statement None., (Copyright © 2023. Published by Elsevier Ltd.)

This exploratory study was conducted to develop and validate an instrument for measuring the social impact of food waste at the household level. A mixed methodology was employed, commencing with a qualitative approach through in-depth interviews and focus group discussions, to identify the social impact of food waste at the household level. This was followed by a quantitative assessment of the questionnaire's validity and reliability. The process involved seven experts for content validity testing, 150 households for face validity testing, and 202 households for reliability testing. The content validity revealed an I-CVI 0.86-1 and a kappa statistic 0.85-1. The face validity demonstrated I-FVI ≥ 0.90 and S-FVI ≥ 0.95. Additionally, the Cronbach's alpha for the reliability test was 0.743. The questionnaire proved to be a simple, valid, and reliable instrument for measuring the social impact of household food waste. •Mixed method used in developing and validating the questionnaire.•Content validity, face validity, and reliability testing to evaluate a newly developed instrument., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2023 The Authors.)

Introduction and Importance: Disorders of sexual development (DSD) are a rare but disastrous condition. A plethora of biological, psychological, and ethical problems surround the management of DSD cases., Case Presentation: A case of 25-year-old woman with a complaint of primary amenorrhea was presented. She wanted to be examined as she had planned to be married. However, examinations revealed that she had 46, XY karyotype, complete androgen insensitivity syndrome, and vaginal agenesis. After several family meetings, the patient, her family, and her partner decided that she would remain as a woman despite the results., Clinical Discussion: Disorders of sexual development are not only about the biological complexities, but also the psychological, social, and ethical dilemmas faced by both the patient and clinicians. A coordinated care team plays a crucial role in addressing the unique challenges presented by DSD, particularly for those diagnosed later in life., Conclusion: Comprehensive and multidisciplinary approach is essential for managing DSD patients., Competing Interests: Declaration of competing interest The funding for this study was obtained via a research grant provided by Universitas Indonesia. The authors declare no other conflict of interests in this study., (Copyright © 2023. Published by Elsevier Ltd.)