1. Optimization of polyhydroxyalkanoates fermentations with on-line capacitance measurement.
- Author
-
Li L, Wang ZJ, Chen XJ, Chu J, Zhuang YP, and Zhang SL
- Subjects
- Biomass, Cupriavidus necator cytology, Cupriavidus necator drug effects, Cupriavidus necator metabolism, Oxygen metabolism, Phosphates pharmacology, Polyhydroxyalkanoates biosynthesis, Time Factors, Electric Capacitance, Fermentation drug effects, Online Systems, Polyhydroxyalkanoates metabolism
- Abstract
The aim of this work was to provide an effective methodology for optimization of the polyhydroxyalkanoates (PHAs) fermentation with Ralstonia eutropha by the on-line capacitance measurement. The present study found the capacitance values could reflect variations of microbial morphology and viability. Furthermore, oxygen uptake rate, specific oxygen uptake rate and specific growth rate were measured in real-time and compared with the capacitance value. In addition, a fed-batch control strategy based on the on-line capacitance measurement was proposed to improve the PHAs production by 22%., (Copyright © 2014 Elsevier Ltd. All rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF