Author: "von der Leyen H" / Publisher: elsevier - Searchworks@Jio Institute Digital Library Search Results

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Author: Dzau VJ, von der Leyen HE, and Morishita R
Subjects: Animals, Clinical Trials as Topic, Female, Gene Transfer Techniques, Humans, Male, Cardiovascular Diseases therapy, Genetic Therapy methods
Published: 1998

Author: von der Leyen H, Heublein B, Lichtlen PR, Haverich A, Schmitz W, and Scholz H
Subjects: Adult, Aged, Follow-Up Studies, Humans, Middle Aged, Coronary Disease pathology, Cyclic AMP analysis, Heart Transplantation adverse effects, Postoperative Complications pathology
Published: 1992
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Author: von der Leyen H, Schmitz W, Scholz H, and Scholz J
Subjects: Animals, Calcium physiology, Cyclic AMP physiology, Myocardial Contraction, Phosphatidylinositols metabolism, Adrenergic alpha-Agonists pharmacology, Cardiotonic Agents, Myocardium metabolism, Phosphodiesterase Inhibitors pharmacology
Abstract: New knowledge and insight into cardiac muscle physiology and pharmacology together with the development of novel drugs may change the treatment of congestive heart failure in the future. This article reviews two newer inotropic mechanisms currently under investigation. It will place special emphasis on the mechanisms of action of selective cardiac phosphodiesterase inhibition and of alpha 1-adrenoceptor mediated stimulation of the phosphoinositide pathway.
Published: 1989
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