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1. Testing the Reliability of Optical Coherence Tomography to Measure Epidermal Thickness and Distinguish Volar and Nonvolar Skin

Author: Molly E. Baumann, Nina Rossa Haddad, Alyssa Salazar, W. Lee Childers, Shawn Farrokhi, Neil B. Goldstein, Brad D. Hendershot, Lisa Reider, Richard E. Thompson, Michael S. Valerio, Christopher L. Dearth, and Luis A. Garza
Subjects: Epidermal thickness, Nonvolar skin, Optical coherence tomography, Volar skin, Dermatology, RL1-803
Abstract: In persons with limb loss, prosthetic devices cause skin breakdown, largely because residual limb skin (nonvolar) is not intended to bear weight such as palmoplantar (volar) skin. Before evaluation of treatment efficacy to improve skin resiliency, efforts are needed to establish normative data and assess outcome metric reliability. The purpose of this study was to use optical coherence tomography to (i) characterize volar and nonvolar skin epidermal thickness and (ii) examine the reliability of optical coherence tomography. Four orientations of optical coherence tomography images were collected on 33 volunteers (6 with limb loss) at 2 time points, and the epidermis was traced to quantify thickness by 3 evaluators. Epidermal thickness was greater (P < .01) for volar skin (palm) (265.1 ± 50.9 μm, n = 33) than for both nonvolar locations: posterior thigh (89.8 ± 18.1 μm, n = 27) or residual limb (93.4 ± 27.4 μm, n = 6). The inter-rater intraclass correlation coefficient was high for volar skin (0.887–0.956) but low for nonvolar skin (thigh: 0.292–0.391, residual limb: 0.211–0.580). Correlation improved when comparing only 2 evaluators who used the same display technique (palm: 0.827–0.940, thigh: 0.633–0.877, residual limb: 0.213–0.952). Despite poor inter-rater agreement for nonvolar skin, perhaps due to challenges in identifying the dermal–epidermal junction, this study helps to support the utility of optical coherence tomography to distinguish volar from nonvolar skin.
Published: 2024
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2. Monte-Carlo simulation for detecting neutron and gamma-ray simultaneously with CdZnTe half-covered by gadolinium film

Author: J. Byun, J. Seo, Y. Kim, J. Park, K. Shin, W. Lee, K. Lee, K. Kim, and B. Park
Subjects: Monte-Carlo simulation, Neutron detection, Prompt gamma-ray, Simultaneous detection, Gadolinium, CdZnTe, Nuclear engineering. Atomic power, TK9001-9401
Abstract: Neutron is an indirectly ionizing particle without charge, which is normally measured by detecting reaction products. Neutron detection system based on measuring gadolinium-converted gamma-rays is a good way to monitor the neutron because the representative prompt gamma-rays of gadolinium have low energies (79, 89, 182, and 199 keV). Low energy gamma-rays and their high attenuation coefficient on materials allow the simple design of a detector easier to manufacture. Thus, we designed a cadmium zinc telluride detector to investigate feasibility of simultaneous detection of gamma-rays and neutrons by using the Monte-Carlo simulation, which was divided into two parts; first was gamma-detection part and second was gamma- and neutron-simultaneous detection part. Consequently, we confirmed that simultaneous detection of gamma-rays and neutrons could be feasible and valid, although further research is needed for adoption on real detection.
Published: 2023
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3. 24 Correlation of clinical outcomes and poly ADP ribose polymerase activity in high grade serous ovarian cancer

Author: Elaine T. Fleming, Hao Chen, Cristel Camacho, Donald McIntire, W. Lee Kraus, and Jayanthi Lea
Subjects: Gynecology and obstetrics, RG1-991, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract: Objectives: PARP proteins are regulators of DNA damage repair in the cell. PARP inhibitors (PARPi) are a class of drugs used to treat ovarian cancer especially in patients with BRCA 1/2 gene mutations and homologous recombination deficiencies. These have previously been used as biomarkers to predict response to PARPi. Preclinical studies suggest that the levels of PARP-1, DDX21, and poly ADP ribosylation (PAR) are indicators of PARP activity. ADP ribosylation (PAR/ MAR) have been suggested as biomarkers to predict PARPi sensitivity. We sought to evaluate the correlation between PARP-1, DDX21, and mono-ADP ribosylation (MAR) expression with response to treatment with PARPi and survival outcomes. Methods: Tissue samples were collected from primary or metastatic sites of 49 patients with high grade serous ovarian cancer who had been prescribed a PARPi. A tumor microarray was made and immunohistochemistry (IHC) for MAR, PARP-1, and DDX21 was performed. IHC staining was graded on a 3-point scale. Clinical data collected included demographics, stage, presence of BRCA mutation, cytore-ductive status, time on PARPi, other adjuvant and salvage treatments, and survival outcomes. Kaplan-Meier analysis and Cox regression analysis were used to determine the effect of the biomarkers on survival outcomes and time on PARPi. Results: We found longer treatment with PARPi was associated with improved overall survival (p
Published: 2023
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4. ASSOCIATIONS OF WATER, SANITATION, AND HYGIENE WITH TYPHOID FEVER IN CASE-CONTROL STUDIES: A SYSTEMATIC REVIEW AND META- ANALYSIS

Author: C. Kim, G. R Goucher, B. Tilahun Tadesse, W. Lee, K. Abbas, and J.-H. Kim
Subjects: Infectious and parasitic diseases, RC109-216
Abstract: Intro: Typhoid fever is a major public health issue in low- and middle-income countries. It is transmitted through fecally contaminated food or water and thus improving water, sanitation, and hygiene (WASH) is considered key to its control. We sought to quantify the association between WASH and typhoid fever. Methods: We updated a previous review by including new findings from the literature indexed in Web of Science, Embase, and PubMed. We kept the search terms, typhoid and case-control, consistent with the previous review. We assessed the risk of bias using the Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I). We categorized WASH exposures according to the WHO/UNICEF Joint Monitoring Programme for Water Supply, Sanitation and Hygiene (JMP) classification. We conducted a Bayesian random-effects meta- analysis of odds ratios (ORs) extracted from the studies without a critical risk of bias. Findings: We identified 25 eligible articles including 19 articles from the previous review. Pooled ORs indicated limited hygiene (OR = 2.26, 95% CrI: 1.38 to 3.64), untreated water (OR = 2.21, 95% CrI: 1.53 to 3.48) and using surface water (OR = 2.16, 95% CrI: 1.24 to 3.60) increased odds of culture-confirmed typhoid fever. On the other hand, basic hygiene (OR = 0.6, 95% CrI: 0.38 to 0.97) and treated water (OR = 0.62, 95% CrI: 0.41 to 0.89) reduced odds of culture-confirmed typhoid fever. Conclusion: Our analyses updated quantitative evidence of association between WASH and typhoid fever. Our study findings will be useful to infer actionable insights on the most effective ways to control typhoid fever in low- and middle-income countries. Our analyses also offer a possibility to leverage JMP WASH data to explore potential burden of typhoid fever.
Published: 2023
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5. THE GENOMIC POPULATION STUDY OF BLOODSTREAM ASSOCIATED ESCHERICHIA COLI IN 2020 IN SOUTHWEST, UK

Author: W. Lee, P. Williams, and M. Avison
Subjects: Infectious and parasitic diseases, RC109-216
Abstract: Intro: Bloodstream infections (BSIs), predominantly caused by Escherichia coli, are an increasing clinical challenge. Rapid empiric antimicrobial therapy is vital for management for BSIs, therefore understanding the genotypic basis of resistance can contribute to improving empiric choice. Methods: This study investigates the molecular epidemiology of 669 deduplicated, sequential E. coli isolated from BSI by a regional diagnostic laboratory serving a population of 1.5 million people between January and December 2020. E. coli were sequenced on the Illumina-HiSeq-2500. Sequencing data were interrogated for AMR determinants and phylogenetic relationships. Using a combination of antimicrobial susceptibility and sequencing data, the concordance of antimicrobial resistance prediction based on detection of resistant determinants and resistance was evaluated. Findings: ST131 was the predominantly identified sequence type (20%) harbouring resistance genes associated with ß-lactams, aminoglycosides and sulphonamides. Genotypic-phenotypic concordance across the antimicrobial panel was lowest and highest for amoxicillin-clavulanate and cefotaxime respectively. Phylogenetic relationships showed resistance was dispersed and intermixed with isolates from different phylogroups. Phylogroups represented were: A (5%), B1 (6%), B2 (66%) and D (16%). χ2 analysis of phylogroup B2 versus A and B1 revealed there was a strong association (p
Published: 2023
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6. GENOMIC ANALYSIS TO UNDERSTAND NON-TYPHOIDAL SALMONELLA CARRIAGE: SALMONELLA AGONA – THE BUG THAT WON'T GO AWAY

Author: W. Lee, E. Waters, A. Ismail, G. Langridge, and M. Chattaway
Subjects: Infectious and parasitic diseases, RC109-216
Abstract: Intro: Salmonella Agona is a non-typhoidal Salmonella known for biofilm production and persistence in the environment and dry food products. S. Agona has been associated with multiple outbreaks and is associated with shedding in pigs, sheep and gulls but little is known about potential carriage in humans or whether large-scale genomic rearrangements play a role in persistent infections. Methods: A review of 2,233 S. Agona isolates from infections in England and associated carriage was undertaken from 2004-2020 in which 1,155 had short read sequencing data available. A representative set of 221 isolates of varying carriage status (Acute, n=77, Convalescent carrier, n=86, Temporary carrier, n=36 and chronic carrier, n = 22) were selected for long read sequencing on the Oxford Nanopore MinION, and genomic arrangement analysis using Socru. The sequence data were also interrogated for AMR determinants, plasmid presence and phylogenetic relationships. Findings: Carriage of S. Agona was present in 6.5% of isolates received at UKHSA (n=144/2,233). Investigation into genome structures of S. Agona revealed both the conserved arrangement GS1.0 and GS25.113, an imbalanced rearrangement where the origin and terminus were much closer together than in GS1.0, producing one very short and one very long replicore. All isolates harboured genotypic resistance to at least 1 antimicrobial class, and many were deemed multi-drug resistant (genotypic resistance to at least 3 classes) with Incl1, IncX1 and colRNAI plasmids most commonly found in the most multi-drug resistant isolates. Phylogenetic analysis indicated that isolates associated with carriage were distributed across the phylogeny intermixed with isolates that caused acute infection. Conclusion: This study reveals that human carriage of S. Agona occurs over a range of timeframes and that the levels of AMR detected across the collection are of concern for treatment of persistent infection. We also identified an unusual genome arrangement using long read sequencing which is undergoing further investigation.
Published: 2023
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7. Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression

Author: Tim Y. Hou and W. Lee Kraus
Subjects: CP: Molecular biology, Biology (General), QH301-705.5
Abstract: Summary: To better understand the functions of non-coding enhancer RNAs (eRNAs), we annotated the estrogen-regulated eRNA transcriptome in estrogen receptor α (ERα)-positive breast cancer cells using PRO-cap and RNA sequencing. We then cloned a subset of the eRNAs identified, fused them to single guide RNAs, and targeted them to their ERα enhancers of origin using CRISPR/dCas9. Some of the eRNAs tested modulated the expression of cognate, but not heterologous, target genes after estrogen treatment by increasing ERα recruitment and stimulating p300-catalyzed H3K27 acetylation at the enhancer. We identified a ∼40 nucleotide functional eRNA regulatory motif (FERM) present in many eRNAs that was necessary and sufficient to modulate gene expression, but not the specificity of activation, after estrogen treatment. The FERM interacted with BCAS2, an RNA-binding protein amplified in breast cancers. The ectopic expression of a targeted eRNA controlling the expression of an oncogene resulted in increased cell proliferation, demonstrating the regulatory potential of eRNAs in breast cancer.
Published: 2022
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8. Clinical outcomes and optimal strategies in primary female urethral cancer - a retrospective analysis at a single institute

Author: W. Lee, M. Park, J. Jun, J. Lee, S. Lee, H. Chae, D. Lee, B. Lim, Y.S. Kyung, Y. Alsowayan, D. You, C. Song, I.G. Jeong, J.H. Hong, H. Ahn, C. Kim, and B. Hong
Subjects: Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2020
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9. Changes in metabolic syndrome associated with prostate change over a 5 year period: Multicenter study

Author: Y.S. Kyung, B. Lim, W. Lee, D. Lee, S. Lee, H. Chae, D. You, C. Song, I.G. Jeong, B. Hong, J.H. Hong, H. Ahn, C. Kim, S.J. Kim, Y.J. Jung, and J. Jeong
Subjects: Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2020
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10. Early experiences of ureterectomy and ileal ureter replacement for urothelial carcinoma of ureter

Author: H. Chae, W. Nam, H. Mohammad, Y.S.A. Alsowayan, M. Park, J. Jun, J. Lee, S. Lee, D. Lee, W. Lee, B. Lim, D. You, C. Song, I.G. Jeong, J.H. Hong, C. Kim, H. Ahn, and B. Hong
Subjects: Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2020
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11. The renal tumor contact surface area using deep convolutional neural net is new method for predicting the renal function after partial nephrectomy

Author: B. Lim, M. Park, J. Jun, J. Lee, S. Lee, H. Chae, D. Lee, W. Lee, Y.S. Kyung, D. You, C. Song, I.G. Jeong, B. Hong, J.H. Hong, H. Ahn, and C-S. Kim
Subjects: Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2020
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12. Fully automated evaluation of contact surface area between renal cell carcinoma and kidney parenchyma using deep convolutional neural net

Author: Y.S. Kyung, T. Kim, S. Ham, W. Lee, B. Lim, D. Lee, H. Chae, D. You, C. Song, I.G. Jeong, B. Hong, J.H. Hong, H. Ahn, N. Kim, and C. Kim
Subjects: Diseases of the genitourinary system. Urology, RC870-923, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published: 2020
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13. Assessment of whole-genome sequencing for predicting Mycobacterium tuberculosis drugs resistance

Author: W. Lee, C. Chang, W. Lin, M. Wu, and R. Jou
Subjects: Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270
Published: 2020
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14. Dynamics of sheath-connected plasma filaments in magnetic field with arbitrary geometry

Author: A.A. Stepanenko, W. Lee, and S.I. Krasheninnikov
Subjects: Nuclear engineering. Atomic power, TK9001-9401
Abstract: We present the results of analysis of sheath-connected blob dynamics in magnetic field with arbitrary geometry. For the case of magnetic configurations with small curvature of the field lines it is demonstrated that motion of a plasma filament can be described by a single time-independent effective potential. Dynamics of blobs in magnetic fields with non-zero curvature of the field lines is also analyzed and we show that depending on filament dimensions and geometry of the magnetic field blobs can demonstrate different propagation patterns. The qualitative results of the presented analysis are supplied with results of simulations of filament dynamics in sheared and non-sheared tokamak-like magnetic configurations. Keywords: Plasma filaments, Blob dynamics, Magnetic field with arbitrary geometry, Magnetic shear
Published: 2017
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15. The autism puzzle: Diffuse but not pervasive neuroanatomical abnormalities in children with ASD

Author: D. Sussman, R.C. Leung, V.M. Vogan, W. Lee, S. Trelle, S. Lin, D.B. Cassel, M.M. Chakravarty, J.P. Lerch, E. Anagnostou, and M.J. Taylor
Subjects: Autism Spectrum Disorder (ASD), Magnetic resonance imaging (MRI), Pediatric neuroanatomical development, Cerebellar hippocampal and basal ganglia volume, Cortical anatomy, Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429
Abstract: Autism Spectrum Disorder (ASD) is a clinically diagnosed, heterogeneous, neurodevelopmental condition, whose underlying causes have yet to be fully determined. A variety of studies have investigated either cortical, subcortical, or cerebellar anatomy in ASD, but none have conducted a complete examination of all neuroanatomical parameters on a single, large cohort. The current study provides a comprehensive examination of brain development of children with ASD between the ages of 4 and 18 years who are carefully matched for age and sex with typically developing controls at a ratio of one-to-two. Two hundred and ten magnetic resonance images were examined from 138 Control (116 males and 22 females) and 72 participants with ASD (61 males and 11 females). Cortical segmentation into 78 brain-regions and 81,924 vertices was conducted with CIVET which facilitated a region-of-interest- (ROI-) and vertex-based analysis, respectively. Volumes for the cerebellum, hippocampus, striatum, pallidum, and thalamus and many associated subregions were derived using the MAGeT Brain algorithm. The study reveals cortical, subcortical and cerebellar differences between ASD and Control group participants. Diagnosis, diagnosis-by-age, and diagnosis-by-sex interaction effects were found to significantly impact total brain volume but not total surface area or mean cortical thickness of the ASD participants. Localized (vertex-based) analysis of cortical thickness revealed no significant group differences, even when age, age-range, and sex were used as covariates. Nonetheless, the region-based cortical thickness analysis did reveal regional changes in the left orbitofrontal cortex and left posterior cingulate gyrus, both of which showed reduced age-related cortical thinning in ASD. Our finding of region-based differences without significant vertex-based results likely indicates non-focal effects spanning the entirety of these regions. The hippocampi, thalamus, and globus pallidus, were smaller in volume relative to total cerebrum in the ASD participants. Various sub-structures showed an interaction of diagnosis-by-age, diagnosis-by-sex, and diagnosis-by-age-range, in the case where age was divided into childhood (age
Published: 2015
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16. Case report: Single-stage facial reanimation with bilateral lengthening temporalis myoplasties for immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome related developmental facial palsy

Author: Aidan M. Rose, Fiona N. Smith, Chang W. Lee, Mary Slatter, Andrew Gennery, and Omar Ahmed
Subjects: Surgery, Case Report
Abstract: Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare primary immunodeficiency, typically associated with clinical features of intractable diarrhoea, type 1 diabetes mellitus and eczema. We present a case of IPEX syndrome referred to our regional facial palsy service for smile restoration surgery. The patient presented with dissatisfaction of facial appearance, including mask-like facies and no functional smile. Pre-operative electromyography confirmed normal temporalis muscle activation. Consequently, the patient was offered single-stage bilateral lengthening temporalis myoplasties. The patient reported improved satisfaction with facial appearance. Surgery resulted in good early resting and voluntary symmetry. Oral commissures were elevated at rest improving oral incompetence. This is the first description of facial animation surgery in the context of IPEX syndrome. With careful consideration and patient selection, successful surgical restoration of resting symmetry and dynamic commissural smile can be achieved in this complex cohort of patients.
Published: 2023

17. Epidemiology and Trends of Infective Meningitis in Neonates and Infants Less than 3 Months Old in Hong Kong

Author: Wing Leung, Mabel Siu Chun Wong, Cheuk San Ivan Lam, Yu-Lung Lau, Marco Ho, Mike Yat-wah Kwan, Godfrey Chi-Fung Chan, Jaime S. Rosa Duque, Chi-man Victor Chan, Yu Ming Fu, Chi Hang Wong, So Lun Lee, Ming Sum Rosanna Wong, Patrick Ip, Gilbert T. Chua, Kai-Ning Cheong, Joshua Sung Chih Wong, Ian C. K. Wong, Pamela P. W. Lee, Chi Chiu Shek, and Kwok Piu Lee
Subjects: 0301 basic medicine, Microbiology (medical), Pediatrics, medicine.medical_specialty, 030106 microbiology, Infectious and parasitic diseases, RC109-216, medicine.disease_cause, Antimicrobial resistance, Group B, Meningitis, Bacterial, Streptococcus agalactiae, 03 medical and health sciences, 0302 clinical medicine, Antibiotic resistance, Ampicillin, Streptococcal Infections, Escherichia coli, Medicine, Humans, Meningitis, 030212 general & internal medicine, Antibiotic prophylaxis, Retrospective Studies, Bacteria, business.industry, Streptococcus, Incidence (epidemiology), Infant, Newborn, Infant, Neonates, General Medicine, Antibiotic Prophylaxis, medicine.disease, Anti-Bacterial Agents, Infectious Diseases, Hong Kong, Gentamicin, business, Infants, medicine.drug
Abstract: Objectives: Meningitis in neonates and young infants leads to significant morbidity and mortality worldwide. This study aimed to investigate pathogens, antibiotic resistance and secular change of incidence in Hong Kong. Methods: A retrospective search was performed on meningitis in neonates and infants aged
Published: 2021

18. Reconstruction of total upper eyelid defects using a myocutaneous advancement flap and a composite contralateral upper eyelid tarsus and hard palate grafts

Author: Dimitra M. Portaliou, Benjamin P. Erickson, Oded Ohana, Mohamed S. Sayed, David T. Tse, and Wendy W. Lee
Subjects: RD1-811, Tarsus (eyelids), business.industry, Short Communication, Total upper eyelid defect, Anatomy, medicine.anatomical_structure, Posterior lamella, medicine, Hard palate, Surgery, Eyelid, Reconstruction, business
Published: 2021

19. Response to Central Boost Radiation Therapy in an Unresectable Retroperitoneal Sarcoma: A Case Report

Author: David G. Kirsch, Dan G. Blazer, Jessica W. Lee, and Diana M. Cardona
Subjects: medicine.medical_specialty, Retroperitoneal sarcomas, business.industry, medicine.medical_treatment, Spinal cord involvement, Teaching Case, 030218 nuclear medicine & medical imaging, Radiation therapy, 03 medical and health sciences, 0302 clinical medicine, Oncology, Boost radiation therapy, Symptom relief, Curative treatment, 030220 oncology & carcinogenesis, Medicine, Retroperitoneal sarcoma, Radiology, Nuclear Medicine and imaging, Radiology, business
Abstract: Surgery is the backbone of curative treatment for localized retroperitoneal sarcomas. However, 10% or more are unresectable due to major vascular or spinal cord involvement. Radiation therapy may be used to provide symptom relief, with small retrospective series reporting 5-year local control rates ranging from 23-65%. In this case of unresectable primary retroperitoneal sarcoma, we utilized a novel RT technique with a central boost, which led to marked clinical improvement and up to 16 months of local control.
Published: 2020

20. Does getting along matter? Tourist-tourist rapport in guided group activities

Author: Linda W. Lee, Ian P. McCarthy, and Edward Boon
Subjects: Service (business), Group (mathematics), Strategy and Management, Tourism, Leisure and Hospitality Management, Transportation, Context (language use), Customer satisfaction, Development, Psychology, Social psychology, Tourism
Abstract: Guided group activities, where tourists consume with other tourists, are common and important. Although the tourism and services literature suggests customer-employee rapport impacts customer satisfaction, the composition and impact of tourist-tourist rapport in guided group activities have received minimal attention. We use a three-study mixed method approach to conceptualize and examine tourist-tourist rapport in guided group activities. Study 1 identifies two recognized dyadic dimensions of tourist-tourist rapport (enjoyable interaction and personal connection) and two new group-based dimensions (group attentiveness and service congruity). Study 2 (video experiment) and Study 3 (field experiment) find that enjoyable interaction and personal connection mediate the relationship between group attentiveness and service congruity with satisfaction. Thus, tourist-tourist rapport in a group context is more multidimensional and complex than previously conceptualized for customer-employee rapport and non-group contexts. Further, we find tourist-tourist rapport is a critical service factor such that high levels satisfy, while low levels dissatisfy.
Published: 2021

21. Congenital cecal diverticulitis in a pediatric patient

Author: Eric A. Albright, Brandon P. Brown, Zachary W. Lee, and Troy A. Markel
Subjects: Abdominal pain, medicine.medical_specialty, RD1-811, Cecal diverticulitis, Pediatrics, Article, RJ1-570, 03 medical and health sciences, 0302 clinical medicine, Medicine, Ascending colon, Congenital diverticulum, Pediatric, medicine.diagnostic_test, business.industry, Incidence (epidemiology), General surgery, Diverticulitis, medicine.disease, Work-up, Endoscopy, 030220 oncology & carcinogenesis, Pediatrics, Perinatology and Child Health, Diverticular disease, 030211 gastroenterology & hepatology, Surgery, Differential diagnosis, medicine.symptom, business
Abstract: Diverticulitis in the pediatric population is a very rare cause of abdominal pain. When present in the cecum or ascending colon, it is often incorrectly diagnosed preoperatively as acute appendicitis. This is especially true in Western countries where right-sided diverticulitis is less common. Here we detail a case of a pediatric patient with complicated congenital cecal diverticulitis and review the literature on pertinent management. An extensive work up with imaging and endoscopy was completed and definitive surgical treatment with diverticulectomy an appendectomy was performed. As the incidence of diverticular disease in younger individuals increases, right sided diverticulitis is worthy of consideration on the differential diagnosis.
Published: 2021

22. Measurement of the azimuthal anisotropy of And mesons in PbPb collisions at

Author: Riccardo Paramatti, Andrea Giammanco, Priyanka Kumari, Susan Gascon, Gunther Roland, K. El Morabit, W. A. T. Wan Abdullah, Jamal Rorie, Ji Hwan Bhyun, Jason Gilmore, Illia Khvastunov, Marco Paganoni, Don Lincoln, Li Yuan, W. De Boer, Jory Sonneveld, Hafeez R Hoorani, Lea Caminada, Alessandro Cardini, Metin Yalvac, Stephan Lammel, Hugo Delannoy, Rong-Shyang Lu, Daniel John Karmgard, Manfred Jeitler, Vladimir Cherepanov, Owen Baron, Vivekanand Jha, Steve Schnetzer, Saranya Ghosh, Simon Regnard, Jiajing Mao, Klaas Padeken, Hasan Ogul, Don Upul Jayasiri Sonnadara, Renato Campanini, Daniel Noonan, M. H.L.S. Wang, D. Valsecchi, Rosamaria Venditti, Sourav Chatterjee, M. Alhusseini, W. J. Metzger, John Alison, John Perry Cumalat, Swagata Mukherjee, Daniel Pitzl, Toni Sculac, Todor Ivanov, T. Bose, Inkyu Park, Joaquin Emilo Siado, Aliakbar Ebrahimi, Markus Spanring, Carlos Lourenco, Leonid Levchuk, Luca Scodellaro, Najaf Amin, A. Braghieri, T. Sarkar, N. De Filippis, Evgueni Vlasov, Maksat Haytmyradov, Paolo Montagna, Thomas Berger, M. Ramirez-Garcia, Oliver Gutsche, Kurtis F Johnson, Joachim Baechler, J. Madhusudanan Sreekala, Othmane Bouhali, Greg P Heath, Luca Perrozzi, Manfred Krammer, Milan Stojanovic, Carlos Erice, R. Granier de Cassagnac, Kevin Sung, Christos Roskas, H. Zhang, David Mason, Maxime Gouzevitch, Andrea Beschi, Maria Cepeda, Jorgen D'Hondt, Konstanty Sumorok, Marek Niedziela, Christoph Schäfer, Alexander Grohsjean, Dimitrios Tsitsonis, Luigi Moroni, Luca Lista, Andreas Pfeiffer, Alessandra Cappati, Kreso Kadija, L. R. Sulak, Julie Malcles, Fengwangdong Zhang, A. Scribano, Daniela Schäfer, Davide Piccolo, T. Mitchell, Bahareh Roozbahani, Nadeesha Wickramage, M. A. Segura Delgado, Lev Uvarov, Rajdeep Mohan Chatterjee, Samandeep Sharma, He He, David Krofcheck, Yi-ting Duh, Boris Grynyov, Shengquan Tuo, Abhigyan Dasgupta, Zviad Tsamalaidze, Nikolai Skatchkov, J. P. Fernández Ramos, Anna Zanetti, Q. Ingram, L. Valencia Palomo, S. Gianì, Andrew Evans, Paul Avery, Salavat Abdullin, Lisa Benato, Roberto Leonardi, Alexander Barnyakov, Quentin Python, Randy Ruchti, Joe Incandela, Luca Cadamuro, Hyunyong Kim, Markus Merschmeyer, Eduardo Coelho, Ozlem Kaya, Sevil Salur, Y. Wang, Marguerite Tonjes, David Mark Raymond, E. O. Olaiya, Maria Savina, Kirill Skovpen, Matthias Schröder, Rachel Yohay, J. K. Lim, F. Simonetto, Adel Terkulov, Sergio P Ratti, David Petyt, Frank Chlebana, W. Van Doninck, Hans Rykaczewski, R.M. Brown, Kuntal Mondal, Giovanni Organtini, Y. J. Mao, Chiara Mariotti, Alessia Saggio, Paolo Spagnolo, P. Gras, W. Ji, Claudio Quaranta, Lindsey Gray, Alberto Belloni, Piet Verwilligen, Jan Eysermans, Attilio Santocchia, Jean Fay, Guido Tonelli, Zeljko Antunovic, A. B. Meyer, Burak Bilki, Nicolò Trevisani, Dirk Krücker, Gianluca Cerminara, Andris Skuja, Lorenzo Russo, Ivica Puljak, Hans Reithler, Minseok Oh, B. McMaster, Fan Xia, Dietrich Liko, Mykhailo Dalchenko, Tamás Álmos Vámi, Jingyu Luo, Prafulla Kumar Behera, Riccardo Andrea Manzoni, Christian Veelken, A. Rossi, Kyungwook Nam, Bobak Hashemi, Tom Cornelis, Shivali Malhotra, Tanmay Mudholkar, Radek Zlebcik, Debabrata Bhowmik, A. Meyer, Russell Richard Betts, Conor Henderson, A. Hervé, Prasenjit Mal, Christina Snyder, Konstantin Matchev, J. J. Hollar, Jean-Marie Brom, Xavier Coubez, Fabrice Couderc, Egidio Longo, Francesca Ricci-Tam, Ivan Marchesini, Christophe Delaere, J. Kaspar, Alex Kamenev, Victor Kim, Willem Verbeke, Armando Lanaro, Piergiulio Lenzi, Daniel Bloch, Mohamed Rashad Darwish, A. G. Stahl Leiton, Vivek Sharma, Andrej Saibel, Salvatore My, Ketino Kaadze, Caglar Zorbilmez, P. C. Tiwari, Christian Contreras-Campana, E. W. Vaandering, Emrah Tiras, Alexander Titterton, Toyoko Orimoto, V. 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Diez Pardos, Michael Wayne Arenton, Shalini Thakur, James John Brooke, Cédric Prieels, F. Fiori, Martina Ressegotti, P. Schütze, Oleksii Turkot, Michele Selvaggi, O. Behnke, Gulsen Onengut, Abhishikth Mallampalli, Viktor Matveev, Carlo Civinini, Clemens Lange, K. Sandeep, Santiago Folgueras, George Alverson, X. Y. Gao, Roman Kogler, Satoshi Hasegawa, Benjamin Kreis, A. Bodek, Oleksii Toldaiev, Mark Pesaresi, Claudia Ciocca, S. Shmatov, F. Torres Da Silva De Araujo, Markus Seidel, Vineet Kumar, A. De Cosa, Hannes Sakulin, Tilman Rohe, Sara Nabili, M. Bluj, Laura Dodd, Andrew Levin, Anton Stepennov, Andrew Loeliger, Andrey Gribushin, Ashley Parker, D. H. Miller, Filippo Errico, Deepak Kumar Sahoo, Jean-Louis Faure, Philipp Millet, Brian Francis, Tamas Ferenc Csorgo, Paolo Checchia, Alberto Messineo, John Almond, Nicholas Eminizer, Daniele Ruini, Michail Bachtis, Bennett Marsh, Duncan Carlsmith, Piotr Zalewski, C. Kleinwort, Xinmei Niu, Dragos Velicanu, Qamar Hassan, Nuno Leonardo, Ashutosh Bhardwaj, Kelly Beernaert, Peter Raics, Peicho Petkov, Leonardo Cristella, Achille Petrilli, Chun-Hua Jiang, G. Ortona, Sushil Chauhan, Kajari Mazumdar, Nickolas Mccoll, Marcus Hohlmann, Sharad Malik, Carlos Florez, Ilaria Vai, Nicolas Postiau, Marco Musich, Fatma Boran, Elena Voevodina, Ioannis Papakrivopoulos, Laurent Thomas, Raffaella Tramontano, Mark Derdzinski, Victor Murzin, Q. Li, Katja Klein, Jens Multhaup, R. F. Harr, Ashish Sharma, Markus Radziej, Roberto Mulargia, Dylan Gilbert, Alessandro Caratelli, Natale Demaria, N. Turini, Navid Rad, Yagya Raj Joshi, and Prasant Kumar Rout
Subjects: Physics, Nuclear and High Energy Physics, Range (particle radiation), Luminosity (scattering theory), Meson, 010308 nuclear & particles physics, Scalar (mathematics), 01 natural sciences, Azimuth, Nuclear physics, 0103 physical sciences, High Energy Physics::Experiment, Rapidity, Nuclear Experiment, 010306 general physics, Anisotropy, Fourier series
Abstract: The second-order Fourier coefficients (v2) characterizing the azimuthal distributions of Image 3 and Image 4 mesons produced in PbPb collisions at sNN=5.02TeV are studied. The Image 5 mesons are reconstructed in their dimuon decay channel, as measured by the CMS detector. The collected data set corresponds to an integrated luminosity of 1.7nb−1. The scalar product method is used to extract the v2 coefficients of the azimuthal distributions. Results are reported for the rapidity range |y|<2.4, in the transverse momentum interval 0
Published: 2021

23. Letter to the editor in response to a letter by Deeks regarding Peto T; UK COVID-19 lateral flow oversight team: COVID-19: Rapid antigen detection for SARS-CoV-2 by lateral flow assay

Author: Tim E. A. Peto and Lennard Y. W. Lee
Subjects: 2019-20 coronavirus outbreak, Medicine (General), Letter to the editor, R5-920, Letter, Coronavirus disease 2019 (COVID-19), Antigen, business.industry, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Medicine, General Medicine, business, Virology
Published: 2021

24. Measurement of CKM matrix elements in single top quark -channel Production in Proton-proton Collisions at

Author: Piergiulio Lenzi, A. G. Stahl Leiton, Andrej Saibel, Salvatore My, T. A. Gómez Espinosa, James Dolen, Radek Zlebcik, Dimitri Bourilkov, Freya Blekman, Ilse Krätschmer, Robert Hirosky, David Michael Morse, L. Layer, G. Hamel de Monchenault, Aditee Rane, Ettore Focardi, John Rander, E. Ayala, Peter Robmann, Debabrata Bhowmik, A. Meyer, Russell Richard Betts, Conor Henderson, Prasenjit Mal, Ibrahim Soner Zorbakir, V. Bunichev, A. A. Abdelalim, S. W. Cho, Andrew Whitbeck, Viktor Veszpremi, Christina Snyder, Konstantin Matchev, J. J. Hollar, Jean-Marie Brom, Ulascan Sarica, Maria Toms, John Michael Marraffino, E. De La Cruz-Burelo, Kenneth Call, Cesar Augusto Bernardes, A. Kasem, Demetra Tsiakkouri, Shawn Zaleski, Rishi Patel, Angelo Giacomo Zecchinelli, Ketino Kaadze, R. Loveless, Tiziano Camporesi, Brent Stone, Louise Skinnari, Vito Palladino, Nural Akchurin, Xavier Coubez, Fabrice Couderc, David Vannerom, Wajid Ali Khan, Inna Kucher, Jelena Mijuskovic, Matej Roguljic, S. Tkaczyk, David Stuart, Alice Mignerey, A. Benecke, Piotr Zalewski, C. Kleinwort, Xinmei Niu, Y. D. Oh, Fabrizio Palla, Christian Contreras-Campana, E. W. Vaandering, Alexander Titterton, V. Re, C. Martin Perez, Thoth Gunter, Kirti Ranjan, Milos Dordevic, I. Gonzalez Caballero, Santeri Laurila, Byung-Sik Hong, Egidio Longo, Francesca Ricci-Tam, Ivan Marchesini, Michael Hildreth, M. S. Meyer, Carsten Hensel, M. M. Defranchis, Matthew Joyce, Anastasia Karavdina, O. Gonzalez Lopez, T. W. Wang, Federica Legger, Tuure Tuuva, M. Medina Jaime, Alexander Schmidt, Nadir Daci, Hannu Siikonen, Frank Jensen, Marco Bozzo, Martina Malberti, Jay Dittmann, Pawan Kumar Netrakanti, Evgueni Tcherniaev, Giuseppe Iaselli, Georgi Sultanov, Evan Wolfe, Kevin Stenson, Samila Muthumuni, Paolo Gunnellini, Juliet Ritchie Patterson, Markus Stoye, Kai Yi, C. Wissing, A. Castaneda Hernandez, Joao Varela, Julie Malcles, Fengwangdong Zhang, A. Scribano, Mohsan Waseem Ather, Anna Stakia, Sébastien Wertz, Leander Litov, Jean-Pierre Merlo, Joanne Cole, A. K. Virdi, Olivér Surányi, Eija Tuominen, Patrick Connor, Colin Jessop, Giovanna Selvaggi, Daniel Abercrombie, Gabor Istvan Veres, Evgenii Tarkovskii, Stefanos Leontsinis, Chayanit Asawatangtrakuldee, Sarah Catherine Eno, Jan-Frederik Schulte, Vladislav Borchsh, Pieter Everaerts, Titas Roy, Alexx Perloff, Roman Ryutin, Federica Primavera, Roberto Carlin, Pierre Depasse, Vyacheslav Klyukhin, M. Van De Klundert, Cecilia Elena Gerber, Victor Golovtcov, Yi-ting Duh, Boris Grynyov, Luisa Benussi, Salvatore Rappoccio, Bożena Boimska, L. Kreczko, Kerem Cankocak, Loukas Gouskos, Richard B. Lipton, Harrison Prosper, Marta Baselga, Mario Deile, D. Domínguez Damiani, P. Das, Diego Beghin, Roberto Dell'Orso, J. W. Gary, Sergey Troshin, Abhishikth Mallampalli, Natalia Korneeva, David D'Enterria, G. Bagliesi, C. Madrid, Shubhajit Das, Vitaly Smirnov, Dragos Velicanu, Qamar Hassan, Nuno Leonardo, Shabnam Jabeen, T. Aushev, Thomas Reitenspiess, Kevin Mcdermott, Dmytro Kovalskyi, Olena Karacheban, C. Mora Herrera, K. A. Ulmer, Vitalii Okhotnikov, Petar Adzic, Maria Margherita Obertino, Alessandro Calandri, M. Calderon De La Barca Sanchez, Gilvan Alves, M. Pelliccioni, Helio Nogima, Anna Teresa Meneguzzo, Stephen Robert Wagner, W. H. Smith, Margaret Zientek, Unki Yang, P. Priyanka, Elif Asli Yetkin, Alberto Orso Maria Iorio, I. Babounikau, A. Ranieri, Livia Soffi, Gabriella Pugliese, Matti J Kortelainen, Cheng-Chieh Peng, Alain Hervé, Yuri Skovpen, R. B. Garg, Christopher Seez, A. Di Mattia, Ada Solano, Felice Pantaleo, Chanwook Hwang, Mário Costa, Niladribihari Sahoo, Apichart Hortiangtham, Maria Savina, Ozgun Kara, Daniel Gastler, Engin Eren, P. Van Mulders, Maksim Azarkin, J. Alcaraz Maestre, Basil Schneider, B. Singh, M. Mohammadi Najafabadi, Michele Gallinaro, Shengquan Tuo, Abhigyan Dasgupta, Zviad Tsamalaidze, Nikolai Skatchkov, A. Baden, M. Barrio Luna, P. Martinez Ruiz del Arbol, Dan Quach, Jeremy Mans, A. Khan, Gobinda Majumder, H. Rejeb Sfar, Vladimir Epshteyn, Daniel Marley, Georgy Antchev, Rylan Conway, J. F. de Trocóniz, D.S. Lemos, Jennifer Chu, J. H. Kim, S. Fonseca De Souza, Matthias Ulrich Mozer, Biagio Rossi, Gouranga Kole, Bruno Galinhas, V. K. Muraleedharan Nair Bindhu, A. Morelos Pineda, Evan Ranken, Christina Reissel, Ryan Mueller, A. Álvarez Fernández, Torben Dreyer, Alessia Tricomi, Nikolay Tyurin, Guillaume Bourgatte, Roumyana Hadjiiska, Fanbo Meng, Caroline Collard, Gage Dezoort, C. Ramón Álvarez, K. Wong, Yen-Jie Lee, Kevin Black, S. B. Oh, Alexander Malakhov, Günter Flügge, Danyyl Brzhechko, Georgios Anagnostou, Melody A. Swartz, Maxwell Chertok, Danek Kotlinski, Jordan Martins, Viktor Khristenko, Gaël Perrin, Umesh Joshi, A. 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Olmedo Negrete, Christophe Royon, Miao Hu, Elizabeth Sexton-Kennedy, Bobae Kim, Efe Yazgan, E. Palencia Cortezon, D. Pérez Adán, Luciano Orsini, Luca Pacher, Claire Shepherd-Themistocleous, Michael Wassmer, C. Oropeza Barrera, Sioni Summers, Sumit Keshri, Antonis Agapitos, Daniel Denegri, D. Horvath, Christopher Brew, Maria Cepeda, Gintautas Tamulaitis, Ilya Gorbunov, Peter Timothy Cox, Marco Zanetti, U. Bhawandeep, Tae Jeong Kim, Robert Schöfbeck, Gabriel Madigan, Jorgen D'Hondt, Daniela Schäfer, Davide Piccolo, T. Mitchell, Marcos Cerrada, Lothar At Bauerdick, Leonardo Giannini, Magda Diamantopoulou, Jeremie Alexandre Merlin, Hartmut Stadie, Andrew Wisecarver, Philip Harris, D. Matos Figueiredo, Noemi Beni, Matthias Wolf, Paolo Ronchese, Badder Marzocchi, K. S. Lee, Patricia McBride, Krzysztof Doroba, Anne Dabrowski, Bryan Caraway, Bennett Marsh, Duncan Carlsmith, T. Y. Ling, Gulsen Onengut, Viktor Matveev, H. Lee, Meng Xiao, Torben Lange, Robin Aggleton, Ferhat Ozok, Jacobo Konigsberg, Dylan Rankin, Andrew Brinkerhoff, Thomas Ferguson, Andrei Gritsan, Tariq Aziz, Dave M Newbold, Daniel Savoiu, Bryan Cardwell, Emmanouil Vourliotis, John Hakala, Andreas Nürnberg, Prasanna Siddireddy, Michael Mulhearn, T. Geralis, Mateusz Zarucki, Korbinian Schweiger, Antoni Shtipliyski, Fatma Boran, Michael Murray, Jakob Salfeld-Nebgen, Elena Voevodina, A. B. Meyer, Burak Bilki, Ioannis Papakrivopoulos, Carlo Civinini, Clemens Lange, K. Sandeep, Santiago Folgueras, George Alverson, X. Y. Gao, Roman Kogler, Satoshi Hasegawa, Benjamin Kreis, A. Bodek, Oleksii Toldaiev, Giuseppe Latino, Mark Pesaresi, Claudia Ciocca, S. Shmatov, Matthew Kilpatrick, Alessandro Giassi, Süleyman Durgut, Louis Moureaux, Sebastian Wiedenbeck, Kunal Kothekar, W. T. Hung, Klaus Rabbertz, Sebastiano Albergo, L. S. Durkin, Gianni Masetti, Márton Bartók, Sanjay Kumar Swain, Marc M Baarmand, Daniele Trocino, A. Stahl, Weinan Si, Robert M Harris, G. Correia Silva, Elliot Hughes, Mohsen Naseri, Igor Lokhtin, Myriam Schönenberger, Gurpreet Singh Chahal, Marko Dragicevic, Anna Kropivnitskaya, Ian Laflotte, Giancarlo Mantovani, Carlo Battilana, Federico Ferri, John Paul Chou, Douglas Berry, C. Mills, Igor Azhgirey, Salvatore Buontempo, Frank Golf, P. Rebello Teles, Amandeep Kaur Kalsi, Leonard Spiegel, Francesco Romeo, Nicolò Trevisani, Andrew Buccilli, Dirk Krücker, Charles C. Richardson, Gianluca Cerminara, Lorenzo Russo, Giorgia Rauco, Nancy Marinelli, Bahareh Roozbahani, P. de Barbaro, Sezen Sekmen, Robert Klanner, Paolo Giacomelli, Andrea Benaglia, George Karathanasis, Y. Choi, Brandon Allen, Erich Schmitz, Lutz Feld, Natascha Krammer, Dustin Burns, Nadeesha Wickramage, Anna Zanetti, Q. Ingram, L. Valencia Palomo, A. Vorobyev, E. E. Boos, Ruslan Chistov, Kadri Ozdemir, Laurent Thomas, Raffaella Tramontano, Mark Derdzinski, Siddhesh Sawant, Tahereh Sadat Niknejad, S. J. Qian, M. Della Negra, Jose Flix, Maria Isabel Josa, M. Tadel, Eva Halkiadakis, Ilya Kravchenko, Jeroen Hegeman, F. Gasparini, Darin Acosta, Kristian Allan Hahn, Daniele Bonacorsi, Nicholas Haubrich, Prasant Kumar Rout, F. Torres Da Silva De Araujo, Heriberto Castilla-Valdez, Winston Ko, I. De Bruyn, Markus Seidel, Vineet Kumar, Victor Murzin, Reza Goldouzian, Riccardo Paramatti, Andrea Giammanco, Priyanka Kumari, Mohd Nizam Yusli, Vivan Nguyen, Alberto Santoro, H. S. Kim, Y. Musienko, M. C. Fouz, Samuel Boren, Prabhat Ranjan Pujahari, L. J. Sanchez Rosas, Renato Potenza, Zachary Lesko, Nazar Bartosik, Frank Glege, Natalia Lychkovskaya, Maria Teresa Grippo, K. Hurtado Anampa, Jian Wang, Marvin Johnson, Timo Peltola, Virgil E Barnes, Andrzej Novak, Graham Wilson, Michael Schmitt, Grigory Safronov, Carlo Rovelli, Anatoli Zarubin, J. Seixas, Federica Maria Simone, Merve Ince, Etiennette Auffray, Shahram Rahatlou, Urs Langenegger, Rishabh Uniyal, Brian Paul Padley, Justin Williams, O. Zenaiev, James Wetzel, S. Seif El Nasr-storey, Zhaozhong Shi, Nairit Sur, Adrian Byszuk, Plamen Iaydjiev, Maurizio Biasini, D. R. Muller, Paul Avery, Salavat Abdullin, Lisa Benato, L. I. Estevez Banos, Quentin Python, Silvio Donato, Aleksandr Iuzhakov, M. Bharti, V. Sola, Randy Ruchti, Joe Incandela, A. Yagil, Sinan Sagir, Yousen Zhang, Sebastian Wozniewski, Marta Felcini, Z. Liu, Q. Li, Miaoyuan Liu, W. A. T. Wan Abdullah, M. R. Adams, Giuseppe Codispoti, Didier Contardo, Jamal Rorie, Jason Gilmore, Gregor Kasieczka, Vladimir Ivanchenko, Sergey Guts, Inseok Yoon, M. Guchait, Katja Klein, Jens Multhaup, R. F. Harr, C. A. Carrillo Montoya, Ashish Sharma, Pritam Kalbhor, Crisostomo Sciacca, Maxim Goncharov, Emanuele Usai, K. Ehataht, Marco Pieri, Y. Chao, Christoph Garbers, Muhammad Ansar Iqbal, Ian R Tomalin, Sridhara Dasu, Emilio Meschi, R. Bi, Marco Paganoni, Don Lincoln, Zoltan Gecse, Harry Cheung, Peter Schleper, Zhen Hu, W. Haj Ahmad, Zoltan Laszlo Trocsanyi, Li Yuan, W. De Boer, Luca Cadamuro, J. Conway, D. Del Re, Luigi Fiore, Vladimir Cherepanov, David Saltzberg, Anup Kumar Sikdar, Benjamin Krikler, Vladimir Palichik, B. McMaster, Caroline Elisabeth Niniane Niemeyer, Nikitas Loukas, W. T. Lin, Dylan Hsu, Jory Sonneveld, Hafeez R Hoorani, Fan Xia, Dietrich Liko, Mykhailo Dalchenko, Jaebeom Park, Alessio Ghezzi, Abideh Jafari, Gregory Iles, C. F. González Hernández, Tamás Álmos Vámi, Vincent Lemaitre, K. Wichmann, P. Kyberd, Alexis Pompili, Johannes Haller, Abraham Tishelman-Charny, Stephen Wimpenny, Vadim Oreshkin, Y. Ershov, Lesya Shchutska, Andrea Massironi, Henning Flacher, Alessandro Cardini, Daniel John Karmgard, Raffaella Radogna, Manfred Jeitler, Mani Tripathi, Rachel Bartek, Marco Peruzzi, Usama Hussain, Owen Rosser Long, Owen Baron, Markus Radziej, Ricardo Lopez-Fernandez, Leszek Grzanka, S. Consuegra Rodríguez, K. Osterberg, Hasan Ogul, Francesco Navarria, Sotiroulla Konstantinou, Tai Sakuma, Don Upul Jayasiri Sonnadara, Simone Scarfi, Raman Khurana, Alexandros Attikis, Maximilian Heindl, Jingyu Luo, Davide Fiorina, Anterpreet Kaur, Paul Baillon, Artur Apresyan, Prafulla Kumar Behera, Yutaro Iiyama, Marc Besancon, Dinyar Rabady, Mehmet Kaya, Vivekanand Jha, Jee-Young Jasmine Choi, Wolfram Dietrich Zeuner, Steve Schnetzer, Saranya Ghosh, Klaas Padeken, Renato Campanini, John Perry Cumalat, Swagata Mukherjee, Roberto Mulargia, Dylan Gilbert, Bradley Cox, Malgorzata Kazana, Alexander Toropin, Alessandro Caratelli, Natale Demaria, Rosamaria Venditti, W. J. Metzger, Nikolaos Manthos, Martin Grunewald, Riccardo Andrea Manzoni, Christian Veelken, Yu. Andreev, Markus Klute, J. Piedra Gomez, N. Turini, Wolfram Erdmann, Toni Sculac, Todor Ivanov, Francesca Cavallari, M. J. Kim, Paolo Dini, S. Bheesette, Fabio Ravera, Manfred Paulini, Dana Z. Anderson, Rajat Gupta, Intae Yu, Mara Senghi Soares, Serguei Ganjour, Carlos Lourenco, Svenja Schumann, Rami Kamalieddin, Cesare Calabria, M. Csanad, Nicola Amapane, Anna Elliott-Peisert, Jessica Prisciandaro, Pierluigi Bortignon, Najaf Amin, A. Braghieri, T. Bose, Christopher George Tully, Inkyu Park, M. Ramirez-Garcia, Vuko Brigljevic, Alexander Belyaev, Claudio Campagnari, Lucia Silvestris, David Taylor, B. Jayatilaka, Aran Garcia-Bellido, Andreas Nowack, Alexander Savin, M. Finger, Koushik Mandal, Caleb Fangmeier, S. Cerci, Joel Goldstein, Luciano Ristori, Milena Misheva, Luigi Calligaris, Kevin Pedro, Oliver Gutsche, Matthias Schnepf, Silvano Tosi, Ryan Heller, Maxime Guilbaud, T. Sarkar, Vinicius Massami Mikuni, M. P. Rauch, Daniel Rosenzweig, Ugo Gasparini, Veikko Karimäki, Debarati Roy, Furkan Dolek, Franco Ligabue, Joachim Baechler, Silvia Taroni, Maria Giulia Ratti, Daniel Treille, Kelvin Mei, S. R. Dugad, D. De Jesus Damiao, Andreas Pfeiffer, Alessandra Cappati, Maren Tabea Meinhard, Rogelio Reyes-Almanza, Nikola Godinovic, Hualin Mei, Stephanie Brandt, Altan Cakir, Paolo Meridiani, R. Mankel, Aron Soha, Geum Bong Yu, Wolfgang Lohmann, Darien Wood, Jyothsna Rani Komaragiri, Filip Moortgat, Konstantinos Kousouris, Luca Perrozzi, Manfred Krammer, Arne Reimers, Kevin Sung, Konstanty Sumorok, Kenneth Long, Andrea Carlo Marini, Alexander Tapper, Kreso Kadija, Vyacheslav Krutelyov, Sara Fiorendi, Deborah Pinna, D. R. Mendis, Igor Vorobiev, Hyunyong Kim, Vasken Hagopian, Michael Reichmann, G. M. Dallavalle, Tamas Novak, Martin Delcourt, Francesco Fallavollita, A. M. Vargas Hernandez, German Martinez, Anton Babaev, Kirill Skovpen, Joshua Bendavid, Nicanor Colino, Bhargav Madhusudan Joshi, Georgios Krintiras, Matteo Presilla, Zeynep Demiragli, Marina Kolosova, Yalcin Guler, Dennis Noll, Julie Managan Hogan, T. Susa, Cristina Botta, Jonathon Langford, Viesturs Veckalns, Simon Kurz, A. Bat, Elizabeth Starling, Nan Lu, René Caspart, Elisabetta Manca, Christoph Grab, Ian Watson, Nicholas John Hadley, Jehad Mousa, Karl Matthew Ecklund, Dario Bisello, Pascal Paganini, R. Walsh, Jonas Rembser, S. Zhang, Maria Agnese Ciocci, Maria Florencia Canelli, Fabrizio Ferro, Roger Wolf, Panos A Razis, John Gabriel Acosta, Lev Dudko, Jeremy Andrea, Thomas Ferbel, Marta Ruspa, Stepan Obraztsov, A. Rizzi, Maral Alyari, Anshul Kapoor, S. Abu Zeid, A. Richards, Henning Kirschenmann, Paul Lujan, Marta Verweij, Hong Ni, W. T. Ford, P. J. Fernández Manteca, Luca Guzzi, Pierluigi Zotto, Hwi Dong Yoo, Robert Bainbridge, Duje Giljanovic, Nadja Strobbe, Jean-Laurent Agram, G. Paspalaki, Steven F. Maier, Anthony Moeller, I. Dremin, P. De Castro Manzano, Anthony Lefeld, Aristotelis Kyriakis, Welathantri Gd Dharmaratna, Ferenc Sikler, Mauro Verzetti, Mario Kadastik, Alexander Dermenev, Minseok Oh, Andrés G Delannoy, Christopher Hill, Dong Ho Moon, Adam Elwood, Sami Lehti, Adish Vartak, Valentina Mariani, Ivan Shvetsov, Igor Golutvin, Mircho Rodozov, Jennifer Ngadiuba, Á. Navarro Tobar, Nicola Bacchetta, Attila Racz, Roberta Arcidiacono, Patrick Jarry, J. D. Lewis, Benjamin Charles Radburn-Smith, Christian Schnaible, Jonathan Fulcher, Anatoli Pashenkov, Avto Kharchilava, Mikhail Ignatenko, Tapio Lampén, Kevin Nash, Thea Klaeboe Aarrestad, Norraphat Srimanobhas, Dermot Moran, Gourab Saha, Valentina Dutta, Vukasin Milosevic, Nikkie Deelen, Radia Redjimi, E. M. Da Costa, Prakash Thapa, Giovanni Abbiendi, Olmo Cerri, Olivier Davignon, Dmitri Konstantinov, Francisco Yumiceva, Ritva Kinnunen, Petar Maksimovic, Patrick Janot, Jan Tomsa, Thorsten Chwalek, Geng-Yuan Jeng, Irene Bachiller, Ivan Mikulec, Francesco Micheli, Gul Gokbulut, Savvas Kyriacou, Denis Rathjens, Alexandre Zabi, S. M. A. Ghiasi Shirazi, Andrius Juodagalvis, Kerstin Borras, Dong-Chul Son, Liliana Teodorescu, P. Busson, Aaron Bundock, Katerina Lipka, Martin Kirakosyan, Georgios Bakas, F. Vazquez Valencia, Clément Leloup, Alexander Nikitenko, Jasvinder A. Singh, M. Rahmani, Dipanwita Dutta, Meena Meena, Alexei Safonov, Janos Erö, Michael Revering, Julia Velkovska, Sudha Ahuja, Nikolai Gorbounov, Halil Saka, Pietro Govoni, Guenter Eckerlin, Armen Tumasyan, Paula Eerola, Manoj Sharan, C. E. Flores, Rui Xiao, Kevin Burkett, Vipin Bhatnagar, T. Liu, K. F. Chen, L. Malgeri, Kamuran Dilsiz, Seema Bahinipati, Paolo Rumerio, Lorenzo Uplegger, Alexander Fröhlich, Christian Autermann, Kenneth Bloom, Thomas Perry, G. Quast, Hannsjoerg Artur Weber, Gordon H. Hanson, Raffaele Gerosa, Alexander Ledovskoy, Vincent J Smith, F. Vazzoler, Shameena Bonomally, Andrey Pozdnyakov, R. D. Field, L. Viliani, Troy Mulholland, Seungkyu Ha, F. L. Fabbri, Daniele Fasanella, D. Green, Zhiming Wang, Marek Gruchala, Sema Zahid, Sergei Gleyzer, Ana Ovcharova, Andrea Venturi, M. Khakzad, Rino Castaldi, Arun Kumar, Daniele Spiga, J. Alexander, G. M. Bilei, Brian Dorney, Mariarosaria D'Alfonso, Mario Galanti, David Jonathan Hofman, Shubham Pandey, Wei Shi, O. Rieger, Thomas Klijnsma, Zoltan Szillasi, Jussi Viinikainen, W. S. Hou, Nadezda Chernyavskaya, Edoardo Bossini, Juska Pekkanen, F. Rezaei Hosseinabadi, Andrey Uzunian, Christopher Palmer, Rohith Saradhy, Alice Bean, Balazs Ujvari, Petr Volkov, Shervin Nourbakhsh, B. Álvarez González, J. D. Ruiz Alvarez, Giacomo Bruno, Ian Mcalister, Michele Bianco, Antoine Lesauvage, S. Belforte, Nabarun Dev, Johan Borg, A. Bermúdez Martínez, Min Suk Kim, Jack King, R. Vidal, W. E. Johns, Mariana Shopova, Eric Christian Chabert, Paraskevas Gianneios, R. E. Sosa Ricardo, Oliver Pooth, Jan Steggemann, Andrés Cabrera, Sandeep Bhowmik, Dipak Kumar Mishra, J. A. Brochero Cifuentes, Simone Bologna, J. G. Branson, Georg Steinbrück, Barbara Clerbaux, Irene Zoi, Cristina Tuve, R. G. Kellogg, Alexander Pauls, Borislav Pavlov, Vladimir Karjavine, Csaba Hajdu, Emyr Clement, C. Fallon, Mario Masciovecchio, Huilin Qu, Oksana Bychkova, James Letts, Guido Tonelli, Zeljko Antunovic, and CMS Collaboration
Subjects: Physics, Nuclear and High Energy Physics, Top quark, Particle physics, Proton, Unitarity, 010308 nuclear & particles physics, Cabibbo–Kobayashi–Maskawa matrix, Physics beyond the Standard Model, Electroweak interaction, 01 natural sciences, Standard Model, Matrix (mathematics), 0103 physical sciences, 010306 general physics
Abstract: Author(s): Sirunyan, AM; Tumasyan, A; Adam, W; Ambrogi, F; Bergauer, T; Dragicevic, M; Ero, J; Escalante Del Valle, A; Flechl, M; Fruhwirth, R; Jeitler, M; Krammer, N; Kratschmer, I; Liko, D; Madlener, T; Mikulec, I; Rad, N; Schieck, J; Schofbeck, R; Spanring, M; Waltenberger, W; Wulz, CE; Zarucki, M; Drugakov, V; Mossolov, V; Suarez Gonzalez, J; Darwish, MR; De Wolf, EA; Di Croce, D; Janssen, X; Kello, T; Lelek, A; Pieters, M; Rejeb Sfar, H; Van Haevermaet, H; Van Mechelen, P; Van Putte, S; Van Remortel, N; Blekman, F; Bols, ES; Chhibra, SS; D'Hondt, J; De Clercq, J; Lontkovskyi, D; Lowette, S; Marchesini, I; Moortgat, S; Python, Q; Tavernier, S; Van Doninck, W; Van Mulders, P; Beghin, D; Bilin, B; Clerbaux, B; De Lentdecker, G; Delannoy, H; Dorney, B; Favart, L; Grebenyuk, A; Kalsi, AK; Moureaux, L; Popov, A; Postiau, N; Starling, E; Thomas, L; Vander Velde, C; Vanlaer, P; Vannerom, D; Cornelis, T; Dobur, D; Khvastunov, I; Niedziela, M; Roskas, C; Skovpen, K; Tytgat, M; Verbeke, W; Vermassen, B; Vit, M; Bruno, G; Caputo, C; David, P; Delaere, C; Delcourt, M; Giammanco, A; Lemaitre, V | Abstract: The first direct, model-independent measurement is presented of the modulus of the Cabibbo–Kobayashi–Maskawa (CKM) matrix elements |η|Vtb, |η|Vtd, and |η|Vts, in final states enriched in single top quark t-channel events. The analysis uses proton-proton collision data from the LHC, collected during 2016 by the CMS experiment, at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb−1. Processes directly sensitive to these matrix elements are considered at both the production and decay vertices of the top quark. In the standard model hypothesis of CKM unitarity, a lower limit of |η|Vtbg0.970 is measured at the 95% confidence level. Several theories beyond the standard model are considered, and by releasing all constraints among the involved parameters, the values |η|Vtb=0.988±0.024, and |η|Vtd2+|η|Vts2=0.06±0.06, where the uncertainties include both statistical and systematic components, are measured.
Published: 2020

25. Periorbital botulinum toxin A improves photophobia and sensations of dryness in patients without migraine: Case series of four patients

Author: Anat Galor, Wendy W. Lee, Jodi Hwang, Ryan J. Diel, Nandini Venkateswaran, Konstantinos D. Sarantopoulos, Roy C. Levitt, Alexandra E. Levitt, and Andrew J. Rong
Subjects: medicine.medical_specialty, Photophobia, genetic structures, Eyebrow, Case Report, Botulinum toxin a, 03 medical and health sciences, 0302 clinical medicine, lcsh:Ophthalmology, Ophthalmology, medicine, Migraine treatment, Botulinum toxin A, Neuropathic-like dry eye syndrome, business.industry, Dry eye syndrome, Levator Palpebrae Superioris, medicine.disease, eye diseases, medicine.anatomical_structure, Migraine, lcsh:RE1-994, 030221 ophthalmology & optometry, Dryness, Eyelid, sense organs, medicine.symptom, business, 030217 neurology & neurosurgery, Neuropathic ocular pain
Abstract: Purpose Individuals receiving botulinum toxin A (BoNT-A) injections in the head and neck for migraine treatment have reported decreases in photophobia and sensations of dryness, independent of ocular surface parameters. We hypothesized that patients without migraine but with similar ocular neuropathic-like symptoms would also experience symptomatic improvement with periocular BoNT-A injections, independent of ocular surface changes. Observations We identified four individuals without a history of migraine but with neuropathic ocular pain (symptoms of dryness, burning, and photophobia that were out of proportion to ocular surface findings and unresponsive to ongoing dry eye (DE) therapies). Individuals underwent 1 session of periocular BoNT-A injections. Validated questionnaires (Visual Light Sensitivity Questionnaire-8, Dry Eye Questionnaire-5) assessed photophobia and DE symptoms pre- and 1-month post-injections. All four reported improvements in frequency and severity of photophobia and eye discomfort following BoNT-A injections. Tear film parameters (phenol red thread test, tear break-up time, corneal staining, and Schirmer test) and eyelid (palpebral fissure height and levator palpebrae superioris function) and eyebrow (position) anatomy were also evaluated before and after injections. Despite a unanimous improvement in symptoms, there were no consistent changes in ocular surface parameters with BoNT-A injections across individuals. Conclusions Periocular BoNT-A shows promise in reducing photophobia and sensations of dryness in individuals with neuropathic-like DE symptoms without a history of migraine, independent of tear film, eyelid, or eyebrow parameters.
Published: 2020

26. Early experiences of ureterectomy and ileal ureter replacement for urothelial carcinoma of ureter

Author: B. Lim, M. Park, H. Chae, H. Mohammad, W. Lee, Y.S.A. Alsowayan, I.G. Jeong, J.H. Hong, D. You, J. Lee, W. Nam, H. Ahn, C. Song, D. Lee, S. Lee, C. Kim, J. Jun, and B. Hong
Subjects: medicine.medical_specialty, Ureterectomy, business.industry, Urology, Ileal ureter, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Ureter, medicine.anatomical_structure, medicine, business, Urothelial carcinoma
Published: 2020

27. Clinical outcomes and optimal strategies in primary female urethral cancer - a retrospective analysis at a single institute

Author: H. Ahn, H. Chae, Bumsik Hong, Y.S. Kyung, J. Jun, I.G. Jeong, Y. Alsowayan, D. You, C. Song, M. Park, J. Lee, W. Lee, D. Lee, J.H. Hong, B. Lim, C. Kim, and S. Lee
Subjects: medicine.medical_specialty, business.industry, Urology, General surgery, Retrospective analysis, Medicine, business, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Urethral cancer, lcsh:RC254-282
Published: 2020

28. Immunotherapy with dendritic cells derived from bone marrow hematopoietic stems cells inhibited tumor growth on a TRAMP-C1 syngeneic mouse model of prostate cancer

Author: H. Lee, K. Bong-Min, W Lee, M.Y. Park, Y. Dalsan, Y. Kim, I.G. Jeong, H. Kim, Y.S. Kyung, B. Lim, and C. Kim
Subjects: business.industry, Urology, medicine.medical_treatment, Immunotherapy, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Prostate cancer, Haematopoiesis, medicine.anatomical_structure, Cancer research, medicine, Syngeneic mouse, Tumor growth, Bone marrow, business, Tramp
Published: 2020

29. Fully automated evaluation of contact surface area between renal cell carcinoma and kidney parenchyma using deep convolutional neural net

Author: H. Ahn, Bumsik Hong, S. Ham, D. You, I.G. Jeong, W. Lee, D. Lee, C. Song, J.H. Hong, T. Kim, N. Kim, H. Chae, Y.S. Kyung, B. Lim, and C. Kim
Subjects: Pathology, medicine.medical_specialty, Kidney, Artificial neural network, Chemistry, Urology, medicine.disease, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, medicine.anatomical_structure, Fully automated, Renal cell carcinoma, Parenchyma, medicine
Published: 2020

30. The renal tumor contact surface area using deep convolutional neural net is new method for predicting the renal function after partial nephrectomy

Author: J. Lee, J.H. Hong, Bumsik Hong, Hanjong Ahn, J. Jun, Y.S. Kyung, Dalsan You, H.K. Chae, M. Park, B. Lim, C-S. Kim, W. Lee, In Gab Jeong, S. Lee, C. Song, and D. Lee
Subjects: medicine.medical_specialty, Artificial neural network, business.industry, Urology, medicine.medical_treatment, Renal function, Renal tumor, lcsh:Diseases of the genitourinary system. Urology, lcsh:RC870-923, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Nephrectomy, medicine, business
Published: 2020

31. The UK Coronavirus Cancer Monitoring Project: protecting patients with cancer in the era of COVID-19

Author: Sam Benkwitz-Beford, Ashley Wilder Smith, Jean-Baptiste Cazier, Helen Curley, Naomi Longworth, Simon Branford, Iris Anil, Archana Sharma-Oates, D.J. Hughes, Andrew Edmondson, Naomi A. Campton, Shivan Sivakumar, Alvin J.X. Lee, Thomas Starkey, Vinton Cheng, Jamie J. D’Costa, Anshita Goel, Karin Purshouse, Claire Palles, Gary Middleton, Simon Hartley, Simon Thompson, Anna Olsson-Brown, Rachel Kerr, Christopher P. Middleton, Roland Arnold, Lennard Y W Lee, Carol Sandys, Csilla Várnai, and Piangfan Naksukpaiboon
Subjects: medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Pneumonia, Viral, medicine.disease_cause, Vulnerable Populations, Patient safety, Betacoronavirus, Neoplasms, Pandemic, Medicine, Humans, Intensive care medicine, Pandemics, Coronavirus, biology, business.industry, SARS-CoV-2, Cancer, COVID-19, medicine.disease, biology.organism_classification, United Kingdom, Oncology, Patient Safety, business, Coronavirus Infections
Published: 2020

32. List of contributors

Author: Masashi Abe, Jon D. Ahlstrom, Julie Albon, Julie Allickson, Graça Almeida-Porada, Richard A. Altschuler, Daniel G. Anderson, Nasim Annabi, Judith Arcidiacono, Nureddin Ashammakhi, Anthony Atala, Kyriacos A. Athanasiou, Hani A. Awad, Stephen F Badylak, Gowri Balachander, Wayne Balkan, Jennifer J. Bara, Michael P. Barry, Harihara Baskaran, Matthew L. Bedell, Donald Andrew Belcher, David B. Berry, Hina Bhat, Zuhaib F. Bhat, Sangeeta N. Bhatia, Catherine Clare Blackburn, Anna Blocki, Kevin M. Blum, Matthew A. Bochenek, Lawrence J. Bonassar, Joseph V. Bonventre, Mimi R. Borrelli, Robby D. Bowles, Amy D. Bradshaw, Andres M. Bratt-Leal, Christopher K. Breuer, Luke Brewster, Eric M. Brey, Priscilla S. Briquez, J.A. Buckwalter, Karen J.L. Burg, Timothy C. Burg, Batzaya Byambaa, Prafulla K. Chandra, Amanda X. Chen, Fa-Ming Chen, Shaochen Chen, Julian Chesterman, Arnav Chhabra, Seow Khoon Chong, Richard A.F. Clark, Muriel A. Cleary, M. Coleman, George Cotsarelis, Ronald G. Crystal, Gislin Dagnelie, Mohammad Ali Darabi, Jeffrey M. Davidson, Joseph Davidson, Paolo De Coppi, Derfogail Delcassian, Paul de Vos, Anthony Dominijanni, Ryan Donahue, Allison P. Drain, Craig L. Duvall, Jenna L. Dziki, Abdelmotagaly Elgalad, George Eng, Vincent Falanga, Niloofar Farhang, Lino Ferreira, Donald W. Fink, Heather E. Fleming, Peter Fong, Mark R. Frey, Denise Gay, Sharon Gerecht, Charles A. Gersbach, D.M.R. Gibbs, Simran Gidwani, Shaimar R. González Morales, Ritu Goyal, Maria B. Grant, Andrea Gray, Howard P. Greisler, Tracy C. Grikscheit, Karl Grosh, Farshid Guilak, Jason L. Guo, Yingli Han, Joshua M. Hare, Ammar Mansoor Hassanbhai, Konstantinos Hatzistergos, David C. Hay, Xiao-Tao He, Timothy Henderson, Darren Hickerson, Darren H.M. Hickerson, Abdelkrim Hmadcha, Camila Hochman-Mendez, Chao Huang, Jeffrey A. Hubbell, Joern Huelsmann, Jun Tae Huh, Joshua G. Hunsberger, Leanne E. Iannucci, Haruhisa Inoue, John Jackson, Yangzi Jiang, Vladimir V. Kalinichenko, J.M. Kanczler, Jeffrey M. Karp, F. Kurtis Kasper, Ali Khademhosseini, Ji Hyun Kim, Erin A. Kimbrel, Irina Klimanskaya, Joachim Kohn, Sunil Kumar, Themis R. Kyriakides, Spencer P. Lake, Johnny Lam, Robert Langer, Robert Lanza, Timothy S. Leach, Benjamin W. Lee, Iris Lee, Sang Jin Lee, David Li, Linheng Li, Qian Liu, Alexander V. Ljubimov, Chi Lo, Michael T. Longaker, Javier López-Beas, Jeanne F. Loring, Ying Luo, Ben D. MacArthur, Nicolas N. Madigan, Henning Madry, Renata S. Magalhaes, Nancy Ruth Manley, Jonathan Mansbridge, Jeremy J. Mao, K.M. Marshall, J.A. Martin, M. Martins-Green, Kathryn M. Maselli, Mark W. Maxfield, Kyle W. McCracken, James Melville, Antonios G. Mikos, José del R. Millán, Maria Mirotsou, Daniel T. Montoro, Matthew P. Murphy, Sean V. Murphy, Michael Musillo, Padmalosini Muthukumaran, Adam M. Navara, Christopher E. Nelson, Laura E. Niklason, Craig Scott Nowell, Regis J. O’Keefe, Kathy E. O’Neill, Richard O.C. Oreffo, Ophir Ortiz, Andre Francis Palmer, Serafeim Perdikis, M. Petreaca, Maksim V. Plikus, Christopher D. Porada, Mark Post, Aleš Prokop, Raj K. Puri, Pengxu Qian, Milica Radisic, Micha Sam Brickman Raredon, Ellen Rothman Richie, Paul Rouse, Hooman Sadri-Ardekani, W. Mark Saltzman, Luiz C. Sampaio, Christopher R. Schlieve, Su-Hua Sha, Paul T. Sharpe, V. Prasad Shastri, Yanhong Shi, Thomas Shupe, Dario Sirabella, Aleksander Skardal, J.M.W. Slack, Stephen R. Sloan, Shay Soker, Bernat Soria, Bárbara Soria-Juan, Frank E. Stockdale, Josh Stover, Thomas Stransky, H. Christiaan Stronks, Patrick S. Stumpf, Kyung Eun Sung, Daniel Swarr, Dagmara Szkolnicka, Jun Takahashi, D.K.O. Tang, Winson Tang, Doris A. Taylor, Yao Teng, Swee Hin Teoh, Anthony J. Smith, Elsa Treffeisen, Rocky S. Tuan, Joseph P. Vacanti, Cor van der Weele, Matthew Vincent, Gordana Vunjak-Novakovic, Lars U. Wahlberg, Derrick C. Wan, Anne Wang, Dan Wang, Qiwei Wang, Yanling Wang, Yu-li Wang, Zhanwen Wang, Valerie M. Weaver, J.A. Wells, Jean F. Welter, Feng Wen, Jake Weston, Jeffrey A. Whitsett, James K. Williams, Anthony J. Windebank, Mark Eu-Kien Wong, Stefan Worgall, Iwen Wu, Rui-Xin Wu, Virginia Y. Xie, Malcolm Xing, Kenneth M. Yamada, Shinya Yamanaka, James J. Yoo, Simon Young, Claire Yu, Hanry Yu, Yifan Yuan, William Zacharias, Jason Zakko, Ai Zhang, Yuanyuan Zhang, Zheng Zhang, Chunfeng Zhao, Yimu Zhao, and Laurie Zoloth
Published: 2020

33. Shaping of metal-organic framework UiO-66 using alginates: Effect of operation variables

Author: Carlos A. Grande, Unni Olsbye, Daniel W Lee, Richard Blom, and Terje Didriksen
Subjects: Calcium alginate, Materials science, Alginates, Diffusion, Filtration and Separation, 02 engineering and technology, Metal-organic frameworks, 021001 nanoscience & nanotechnology, MOFs, Analytical Chemistry, Characterization (materials science), Shaping, chemistry.chemical_compound, Adsorption, 020401 chemical engineering, chemistry, Chemical engineering, UiO-66, Slurry, Extrusion, 0204 chemical engineering, 0210 nano-technology, Porous medium, Porosity
Abstract: Shaping of metal-organic frameworks into macro-structured particles for reactors and separation processes is a fundamental step in their way towards commercialization. Extrusion techniques which are used for shaping many porous materials resulted in significant reduction of surface area in many MOF materials and thus alternative techniques are required. One alternative way to shape soft materials is to use a technique coming from molecular gastronomy and biology; the calcium alginate method. For this method, a slurry of the porous material and sodium alginate is prepared and then dropwise put in contact with calcium chloride solution forming spheres. Forming particles with both suitable diffusion and mechanical properties and without significant reductions in surface area, many operating variables must be tuned and optimized. This publication presents the results obtained showing the effects of varying several process variables of the alginate method for shaping UiO-66 MOF. Characterization in terms of surface area and other surface methods, force required to break particles (crushing strength) and measurement of isotherms of carbon dioxide. With this method we have produced MOF particles with crushing strength similar to alumina or silica) and with only 10% of reduction in surface area and adsorption capacity.
Published: 2020

34. Cardiac tissue engineering

Author: Yimu Zhao, George Eng, Benjamin W. Lee, Milica Radisic, and Gordana Vunjak-Novakovic
Published: 2020

35. Management of Cytokine Release Syndrome

Author: Tamila L. Kindwall-Keller, Daniel W. Lee, and Indumathy Varadarajan
Subjects: medicine.medical_specialty, animal structures, business.industry, respiratory system, medicine.disease, Chimeric antigen receptor, Cytokine release syndrome, otorhinolaryngologic diseases, medicine, In patient, Intensive care medicine, business, Grading (tumors), Organ system
Abstract: Cytokine release syndrome (CRS) is the most frequently occurring toxicity in patients treated with chimeric antigen receptor T-cell therapies. The definition and grading of CRS has varied over the years. Only recently has the community come to consensus on these topics. However, consensus CRS management guidelines do not exist owing to the incredibly complex and variable nature of CRS across products and patient populations. This chapter will summarize the historical and current standard approaches to CRS grading then provide a framework and discussion of key points in the management of CRS focusing on supportive care by organ systems and optimal timing of intervention with anti-cytokine therapies.
Published: 2020

36. Contributors

Author: Alia A. Alghwiri, Brady Anderson, Dale Avers, Katherine Beissner, Elizabeth J. Bergman, Marghuretta D. Bland, Richard Briggs, Lawrence P. Cahalin, Tzurei Chen, Cory Christiansen, Kevin K. Chui, Charles D. Ciccone, Cathy Haines Ciolek, Moira Gannon Denson, Cathy S. Elrod, Christine E. Fordyce, Jenny Forrester, Christian Garcia, Rosanna Gelaz, Jared M. Gollie, Greg W. Hartley, Catherine E. Lang, Paul LaStayo, Alan Chong W. Lee, Sin Yi Lee, Daniel Liebzeit, Robin L. Marcus, Caitlin Miller, David M. Morris, Karen Mueller, Cynthia E. Neville, Brian W. Pulling, Paul Reidy, Julie D. Ries, Elizabeth Ruckert, Carol Sames, Ellen Strunk, Anne Thackeray, Martha Townsend, Chris L. Wells, Susan L. Wenker, Susan L. Whitney, Christopher Wilson, Rita A. Wong, and Sheng-Che Yen
Published: 2020

37. Management of Integumentary Conditions in Older Adults

Author: Alan Chong W. Lee
Subjects: business.industry, Medicine, Physiology, Integumentary system, business
Published: 2020

38. List of Contributors

Author: Nabil Ahmed, Jacob S. Appelbaum, Karen Ballen, Cathy Conry Cantilena, Francesco Ceppi, Kenneth Cornetta, Kevin J. Curran, Terry J. Fry, Rebecca A. Gardner, Juliane Gust, Cristina Gutierrez, Steven L. Highfill, Elad Jacoby, Ping Jin, Sujith K. Joseph, Tamila L. Kindwall-Keller, Krishna V. Komanduri, Daniel W. Lee, Kris M. Mahadeo, Eoghan Molloy, Victor M. Orellana-Noia, Rimas J. Orentas, Sandhya Ramanathan Panch, Jae H. Park, Karlo Perica, Navin Pinto, Craig A. Portell, Michael A. Pulsipher, Khaled Sanber, Nirali N. Shah, Haneen Shalabi, David Stroncek, Corinne Summers, Francesco Paolo Tambaro, Agne Taraseviciute, Cameron J. Turtle, Indumathy Varadarajan, Alan S. Wayne, and Kamille A. West
Published: 2020

39. Chapter 5 Biochemical Analyses of Nuclear Receptor‐Dependent Transcription with Chromatin Templates

Author: Ruhl, Donald D., primary and Kraus, W. Lee, additional
Published: 2009
Full Text: View/download PDF

40. Carbohydrates

Author: Adair, W. Lee, primary
Published: 2007
Full Text: View/download PDF

41. Digestion and Absorption of Carbohydrates, Proteins and Lipids

Author: Adair, W. Lee, primary
Published: 2007
Full Text: View/download PDF

42. List of Contributors

Author: Jeremy P. Burton, Ryan M. Chanyi, Jeong Y. Cho, Kang Su Cho, Min Chul Cho, Yang Hyun Cho, Min Soo Choo, Seol Ho Choo, Felix K.-H. Chun, Garrett M. Dancik, Malcolm Dewar, Margit Fisch, Hong Koo Ha, Yun-Sok Ha, Jun Hyuk Hong, Sung-Hoo Hong, Eu Chang Hwang, Jonathan Izawa, Byeong Hwa Jeon, Seung H. Jeon, Byong Chang Jeong, Chang Wook Jeong, Hyeon Jeong, Seung Il Jung, Ho-Won Kang, Minyong Kang, Seok H. Kang, Sung Gu Kang, Bhumsuk Keam, Hyung Suk Kim, Jae Heon Kim, Jeong Hyun Kim, Soodong Kim, Sun Il Kim, Sung Han Kim, Tae-Hwan Kim, Young A. Kim, Luis A. Kluth, Kyungtae Ko, Whi-An Kwon, Jeong W. Lee, Joo Yong Lee, Ok-Jun Lee, Richard J. Lee, Seung W. Lee, Fan Li, Jae Sung Lim, Yuchen Liu, Evangelina López de Maturana, Núria Malats, Gyeong E. Min, Kyung C. Moon, Jong Jin Oh, Sunghyun Paick, Jae Young Park, Jeong Hwan Park, Juhyun Park, Sue Kyung Park, Jong H. Pyun, Gregor Reid, Victor M. Schüttfort, Ho Kyung Seo, Ji Sung Shim, Ju Hyun Shin, Dan Theodorescu, Sungmin Woo, Won Jae Yang, and Seok Joong Yun
Published: 2018

43. Winter pressures on the UK health system dominated by the Greenland Blocking weather regime

Author: Robert W. Lee, Robert W Aldridge, Andrew Charlton-Perez, and Christian M. Grams
Subjects: Return period, Atmospheric Science, medicine.medical_specialty, 010504 meteorology & atmospheric sciences, Public health, Geography, Planning and Development, 0207 environmental engineering, Climate change, Pulmonary disease, 02 engineering and technology, Management, Monitoring, Policy and Law, lcsh:QC851-999, 01 natural sciences, Health services, Climatology, Attributable risk, medicine, Environmental science, Climate model, lcsh:Meteorology. Climatology, 020701 environmental engineering, Cold weather, 0105 earth and related environmental sciences
Abstract: In many countries, wintertime cold weather is linked to ill-health and intense pressure on public health services. This study examines how both long-term climate change and sub-seasonal variability contribute to the temperature extremes that increase pressures on the UK's National Health Service. The impact of temperature on fractional mortality and hospital admissions due to chronic obstructive pulmonary disease are used as metrics of wintertime pressure on the health system. The focus of the study is on days during the year in which the fractional mortality and hospital admissions attributable to cold weather exceed the five-year return period. These days are henceforth called winter pressure days since they likely to lead to significant pressure on the health service to meet demand. On interdecadal and longer timescales, winter pressure days show a robust decline over recent decades with a reduction from a probability of 0.29 in the pre-industrial period to 0.11 for the period 2000–2016. Comparing the risk of winter pressure days in two different climate model simulations of the historical period and a counterfactual ensemble of only natural climate forcings shows that this decline can be clearly attributed to anthropogenic activity. The average Fraction of Attributable risk due to anthropogenic activity for these two climate models for winter pressure days is −0.94. On sub-seasonal timescales, weather drivers of winter pressure days are assessed through analysis of diagnostics of weather regime lifecycles. This analysis shows winter pressure days occur almost exclusively in the Greenland Blocking regime. Although the risk of winter pressure days is likely to continue to decline with current climate trends, there remains a substantial weather driven risk to the UK health system. Preparing for weather events that cause stress on the system should focus on the analysis and prediction of the Greenland Blocking regime on weekly timescales. Keywords: Mortality, Health system, Cold weather, Weather regimes
Published: 2019

44. Search for long-lived particles using nonprompt jets and missing transverse momentum with proton-proton collisions at

Author: Atanu Modak, Nicholas Wardle, Marco Cipriani, Peter Elmer, Tao Huang, Isa Dumanoglu, Stephan Albert Wiederkehr, F. M. Stober, Marcella Diemoz, Davide Zuolo, M. Flechl, David Petyt, W. Van Doninck, Hans Rykaczewski, Mikhail Dubinin, G. Cucciati, Wei Li, Y. J. Mao, Chiara Mariotti, Marco Monteno, Ohannes Kamer Köseyan, H. El Mamouni, Yasser Assran, Valerie Scheurer, Marius Preuten, Alexey Volkov, Suat Ozkorucuklu, Wei Xie, Rainer Wallny, V. Drugakov, Alessio Boletti, Jie Zhang, Nils Faltermann, Duong Nguyen, Vladyslav Danilov, Piero Giorgio Verdini, Ivan Amos Cali, A. Carvalho Antunes De Oliveira, Francesca Romana Cavallo, Viktor Savrin, Matti J Kortelainen, Cheng-Chieh Peng, Dooyeon Gyun, Norbert Neumeister, Mitchell Wayne, Karol Bunkowski, Tanvi Wamorkar, Nabin Poudyal, Sharon Hagopian, Ralf Ulrich, Eshwen Bhal, Giorgio Maggi, Sadia Khalil, C. Fernandez Bedoya, S. Van Putte, Philip Baringer, Enrico Robutti, George Stephans, Prasant Kumar Rout, Stefan Grünendahl, Juliette Alimena, Paul Asmuss, E. J. Tonelli Manganote, Ekaterina Kuznetsova, Diogo Bastos, Sung Keun Park, Marco Verzocchi, Guillaume Bourgatte, Robert Schöfbeck, Gabriel Madigan, Fanbo Meng, Caroline Collard, S. Nandan, A. De Iorio, Pietro Vischia, Fionn Ball, Francisco Matorras, S. Banerjee, John A Coughlan, Riccardo Paramatti, Andrea Giammanco, Priyanka Kumari, Philip Harris, D. Matos Figueiredo, Noemi Beni, Vincenzo Innocente, K. S. Lee, Silvia Maselli, Ioannis Papadopoulos, Efstathios Paganis, R. Frühwirth, Erica Brondolin, M. Della Negra, Georgios Anagnostou, Melody A. Swartz, Maria Isabel Josa, Camille Camen, E. Palencia Cortezon, K. W. Bell, Nataliia Kovalchuk, Dhanush Anil Hangal, Maxwell Chertok, Danek Kotlinski, Jordan Martins, A. Melo, Denis Gelé, Catherine Schiber, Mauro Emanuele Dinardo, Carmen Albajar, Sven Dildick, M. Tadel, Eva Halkiadakis, Frank Glege, W. A. T. Wan Abdullah, Jamal Rorie, Nhan Viet Tran, Mohammad Abrar Wadud, Christof Roland, Jason Gilmore, Marco Paganoni, David Colling, Mikhail Danilov, Pieter David, Alexander Dierlamm, Olga Evdokimov, J. M. Vizan Garcia, Bugra Bilin, Kati Lassila-Perini, Giovanni Petrucciani, Andrea Perrotta, G. B. Yu, Peter Robmann, Petra Merkel, De Hua Zhu, Fuqiang Wang, Sergey Polikarpov, Justin Pilot, Petr Moisenz, David Ja Cockerill, Wolfgang Lange, Erik Gottschalk, Andrea Delgado, Duncan Leggat, Joscha Knolle, Kristian Harder, Wolfgang Funk, Don Lincoln, Li Yuan, W. De Boer, Jory Sonneveld, Hafeez R Hoorani, Alessandro Cardini, Junghwan Goh, Livio Fanò, James Hirschauer, Tiziano Camporesi, Brent Stone, Jorge Chaves, Christopher Brainerd, Si Xie, Amina Zghiche, Emily MacDonald, Danilo Meuser, Andrew Gilbert, Ridhi Chawla, Louise Skinnari, Matthieu Marionneau, Daniel John Karmgard, Mykola Savitskyi, Manfred Jeitler, Valeria Botta, M. De Palma, V. Monaco, Thomas Esch, Vladimir Popov, Jacopo Pazzini, Vito Palladino, Nural Akchurin, Hannu Siikonen, Michal Szleper, Roberto Chierici, Chia-Ming Kuo, P. Major, Nadia Pastrone, Owen Baron, Vivekanand Jha, Steve Schnetzer, Saranya Ghosh, Klaas Padeken, D. Cutts, W. Snoeys, Michael Benjamin Andrews, Simone Paoletti, Frank Jensen, Marco Bozzo, Dimitri Bourilkov, Robert Stone, Patrick Jarry, J. D. Lewis, Benjamin Charles Radburn-Smith, Meenakshi Narain, Mirena Ivova Paneva, Thomas Eichhorn, Alessandro Thea, Isabel Pedraza, Martina Malberti, Jay Dittmann, Paolo Azzurri, Sabino Meola, Roberto Covarelli, Sergio Cittolin, Pawan Kumar Netrakanti, Renato Campanini, Rosamaria Venditti, Evgueni Tcherniaev, W. J. Metzger, K. A. Ulmer, Vitalii Okhotnikov, Petar Adzic, Candan Dozen, Abhijith Gandrakota, C. Diez Pardos, Michael Wayne Arenton, Suchandra Dutta, S. W. Cho, Andrew Whitbeck, Viktor Veszpremi, J. A. Murillo Quijada, Giulio Mandorli, Anne-Marie Magnan, Wagner Carvalho, Carlos Lourenco, Maria Margherita Obertino, Alajos Makovec, Emilien Chapon, Vittorio Raoul Tavolaro, David J. Smith, J. S. H. Lee, Tariq Aziz, Dave M Newbold, Shalini Thakur, I. Gonzalez Caballero, Shabnam Jabeen, Stephane Perries, R. Taus, Jared Sturdy, Kaya Tatar, A. Bornheim, Peisen Ma, Sandra S. Padula, Alexander Nehrkorn, Najaf Amin, A. Braghieri, Terhi Jarvinen, Greg Landsberg, Cécile Caillol, Manjit Kaur, Engin Eren, P. Van Mulders, Michele Gallinaro, Alexey Golunov, P. H. Butler, Tommaso Isidori, Giorgia Miniello, Peter Wittich, I. O. Atakisi, James John Brooke, Cédric Prieels, Martina Ressegotti, P. Schütze, T. Aushev, Thomas Reitenspiess, Kevin Mcdermott, Dmytro Kovalskyi, V. Kutzner, A. Álvarez Fernández, Narumon Suwonjandee, Valentin Sulimov, Francesco Fabozzi, Michal Olszewski, Stefaan Tavernier, Diego Ciangottini, Oleksii Turkot, Alexei Raspereza, Radek Zlebcik, Ketino Kaadze, Luca Perrozzi, Manfred Krammer, Kevin Sung, Anna Colaleo, Marko Dragicevic, Kun Shi, E. Ayala, Yiwen Wen, Paolo Vitulo, Maximilian Knut Kiesel, William J Spalding, Jay Roberts, Stefano Bianco, Brandon Chiarito, H. S. Chen, Yury Ivanov, Andre Sznajder, Francesco Fiori, Yildiray Komurcu, Philippe Busson, J. L. Dulemba, George Karathanasis, Y. Choi, Brandon Allen, Costas Foudas, Gyorgy Vesztergombi, Ali Harb, Dustin Burns, Prabhat Ranjan Pujahari, Ibrahim Soner Zorbakir, Frank Jm Geurts, Konstanty Sumorok, Semiray Girgis, Christian Contreras-Campana, E. W. Vaandering, Alexander Titterton, V. Re, M. Fernandez, S. Somalwar, Pedrame Bargassa, Michele Selvaggi, O. Behnke, Gulsen Onengut, Viktor Matveev, Wajid Ali Khan, Devdatta Majumder, C. A. Salazar González, Smarajit Karmakar, H. Lee, Carlo Civinini, Clemens Lange, K. Sandeep, Santiago Folgueras, George Alverson, X. Y. Gao, Roman Kogler, Serdal Damarseckin, S. Choi, Kevin Nash, Satoshi Hasegawa, Benjamin Kreis, A. Bodek, Oleksii Toldaiev, Debabrata Bhowmik, Adrian Perieanu, A. Meyer, Dominique Gigi, Gourab Saha, Valentina Dutta, A. P. Singh, Yuri Gershtein, Russell Richard Betts, Conor Henderson, Prasenjit Mal, Santeri Laurila, Christina Snyder, Konstantin Matchev, J. J. Hollar, Jean-Marie Brom, Inna Kucher, Emmanuelle Perez, L. J. Sanchez Rosas, Urs Langenegger, G. G. Da Silveira, S. Tkaczyk, Andrew Carnes, Giuseppe Barbagli, Salvatore Nuzzo, Philippe Bloch, Cristina Riccardi, Stephen Sanders, Alexander Schmidt, Arnaud Steen, Boaz Klima, J. S. Kim, Michael Tytgat, David Lange, Nadir Daci, David Sheffield, Matej Roguljic, K. H. M. Kwok, Kira Burt, Guido Tonelli, Claudio Caputo, C. De Oliveira Martins, Victor Golovtsov, Martina Vit, Grant Riley, Robert Fischer, Laurent Forthomme, Lorenzo Bianchini, Maksym Titov, Daniel Klein, Raffaello D'Alessandro, Adrian Byszuk, Pritam Kalbhor, Zehui Zhang, Eleni Erodotou, Francois Lagarde, Fatma Boran, A. Escalante Del Valle, Zeljko Antunovic, Christoph Paus, Piergiulio Lenzi, Mark Pesaresi, Claudia Ciocca, S. Shmatov, F. Torres Da Silva De Araujo, Vukasin Milosevic, David Stuart, Alice Mignerey, A. Benecke, L. Viliani, Troy Mulholland, Elena Voevodina, Ioannis Papakrivopoulos, Roberto Dell'Orso, Markus Seidel, Robin Erbacher, Joosep Pata, Colin Bernet, Ugur Kiminsu, Ping Tan, Crisostomo Sciacca, Senta Greene, C. Baldenegro Barrera, Dylan Teague, Vineet Kumar, J. W. Gary, Maxim Goncharov, K. Ehataht, Xavier Coubez, Fabrice Couderc, Egidio Longo, Francesca Ricci-Tam, Ivan Marchesini, Sergey Troshin, J. Lykken, Pasquale Musella, A. G. Stahl Leiton, Andrej Saibel, Matthias Schröder, A. Rossi, Kyungwook Nam, Marco Pieri, David Fehling, Christoph Garbers, Ian R Tomalin, David Saltzberg, Mohsan Waseem Ather, Anna Stakia, Sébastien Wertz, Evgenii Tarkovskii, Martti Raidal, A. Romero, C. Scharf, Siarhei Shulha, Tuure Tuuva, Andrei Sobol, H. Bakhshiansohi, Yangyang Cheng, Andrea Bocci, Federico Ferri, Douglas Berry, M. Medina Jaime, Salvatore My, T. A. Gómez Espinosa, Sihyun Jeon, Pirmin Berger, Tommaso Dorigo, Sandra Malvezzi, Vladimir Palichik, David D'Enterria, G. Bagliesi, C. Madrid, Helio Nogima, W. H. Smith, Paolo Gunnellini, S. H. Lee, Juliet Ritchie Patterson, Pamela Klabbers, Stefanos Leontsinis, Joao Varela, Igor Azhgirey, Salvatore Buontempo, Frank Golf, Elizabeth Kennedy, Margaret Zientek, Unki Yang, Bobak Hashemi, W. L. Prado Da Silva, Pietro Faccioli, Chayanit Asawatangtrakuldee, Nikkie Deelen, Radia Redjimi, E. M. Da Costa, Caroline Elisabeth Niniane Niemeyer, Candan Isik, James Dolen, Freya Blekman, Ilse Krätschmer, Gabriella Pasztor, R. Loveless, Alessio Magitteri, Ozgun Kara, D. H. Kim, Georg Auzinger, M. Aldaya Martin, Jindrich Lidrych, Prakash Thapa, A. Rinkevicius, David Vannerom, Angelo Giacomo Zecchinelli, Daniel Gastler, Alberto Zucchetta, V. Petrov, Burin Asavapibhop, Xunwu Zuo, Zukhaimira Zolkapli, Giovanni Abbiendi, Olmo Cerri, Elif Asli Yetkin, Alberto Orso Maria Iorio, Felice Pantaleo, Chanwook Hwang, Mário Costa, David Michael Morse, G. Hamel de Monchenault, Aditee Rane, Salvatore Rappoccio, L. Kreczko, Loukas Gouskos, L. M. Huertas Guativa, Maksim Azarkin, J. Alcaraz Maestre, Basil Schneider, Daniele Pedrini, Benedikt Maier, Shao Min Tan, Laurent Thomas, Mark Derdzinski, James Bueghly, Matthew Nguyen, V. Rodríguez Bouza, Seungkyu Ha, Vyacheslav Valuev, K. B. Lee, Leander Litov, Konrad Deiters, Vladimir Epshteyn, Olivier Davignon, Dmitri Konstantinov, Alain Givernaud, Seth Moortgat, T. R. Fernandez Perez Tomei, G. B. Mohanty, Jean-Pierre Merlo, Daniel Marley, Ettore Focardi, Harvey B Newman, Jeffrey Berryhill, J. D. Tapia Takaki, Melike Akbiyik, Vallary Bhopatkar, John Rander, F. L. Fabbri, Daniele Fasanella, Tom Cornelis, A. Kayis Topaksu, H. A. Salazar Ibarguen, Ulascan Sarica, Niladribihari Sahoo, Apichart Hortiangtham, M. A. Bhat, Christina Reissel, Ryan Mueller, Torben Dreyer, D. Green, C. S. Moon, Ivan Reid, Christine Mclean, Anastasia Grebenyuk, G. Dissertori, Kithsiri Malagalage, Maria Toms, John Michael Marraffino, E. De La Cruz-Burelo, Kenneth Call, Byung-Sik Hong, Sertac Ozturk, Joanne Cole, A. K. Virdi, Eija Tuominen, P. Sphicas, Anup Kumar Sikdar, Shivali Malhotra, Tanmay Mudholkar, Ennio Monteil, Aldo Penzo, Hao Qiu, Victor Murzin, Rachel Yohay, J. K. Lim, F. Simonetto, Gabriella Pugliese, I. Van Parijs, Muhammad Waqas, Ren-Yuan Zhu, Pascal Vanlaer, Richard Breedon, Shirin Chenarani, Cesar Augusto Bernardes, Jozsef Molnar, Konstantin Androsov, Michael Hildreth, M. S. Meyer, Marino Missiroli, Dmitry Hits, Sergio P Ratti, Tanmay Sarkar, Matthew Joyce, Zhiming Wang, Tai Sakuma, G. P. Van Onsem, Zaixing Mao, Nicolas Tonon, Artur Gottmann, Brian L Winer, Alessia Tricomi, Nikolay Tyurin, Frank Chlebana, Claudia Pistone, Roumyana Hadjiiska, Xavier Janssen, Kuntal Mondal, Pedro G Mercadante, Izaak Neutelings, Giovanni Organtini, Nicolo Cartiglia, Robert Hirosky, Demetra Tsiakkouri, Shawn Zaleski, Jorma Tuominiemi, Predrag Milenovic, Peter R Hobson, Kin Ho Lo, Hans-Christian Kaestli, G. L. Pinna Angioni, F. De Guio, Shane Breeze, Iban Jose Cabrillo, Y. Ban, Rishi Patel, M. I. Nagy, Aimilios Ioannou, John J. Leonard, Patrick Connor, Georgy Antchev, Giovanna Selvaggi, Ioanna Papavergou, David Sperka, Gaelle Boudoul, Nicola Minafra, Johannes Schulz, Gregory Rakness, L. S. Durkin, Souvik Das, Gianni Masetti, Márton Bartók, Wolfgang Waltenberger, Francisco Yumiceva, J. De Clercq, Wolfgang Adam, Ritva Kinnunen, E. 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Johns, Mariana Shopova, Eric Christian Chabert, Tamas Ferenc Csorgo, Paolo Checchia, Sean Flowers, Sandeep Bhowmik, Roberto Sacchi, Tejinder Virdee, Nicolò Tosi, Alexandros Attikis, Jaebeom Park, M. Jones, Sami Lehti, Adish Vartak, Camilla Galloni, Alberto Messineo, Seth Conrad Zenz, I. Heredia-De La Cruz, John Almond, Ricardo Lopez-Fernandez, Vincenzo Daponte, M. Vidal Marono, Julia Thom, Finn Rebassoo, Volker Blobel, Leszek Grzanka, Bradley Cox, David Bertsche, Valentina Mariani, Davide Cieri, Joshua Hardenbrook, Alexander Toropin, Neeti Parashar, S. Roy Chowdhury, Colin Jessop, Svenja Schumann, W. T. Hung, Klaus Rabbertz, Rami Kamalieddin, Ivan Shvetsov, Igor Golutvin, Mircho Rodozov, Sebastiano Albergo, Igor Lokhtin, Myriam Schönenberger, M. P. Rauch, Daniel Rosenzweig, Zachary Lesko, M. Calderon De La Barca Sanchez, Jennifer Ngadiuba, Á. Navarro Tobar, Nicola Bacchetta, Attila Racz, Roberta Arcidiacono, Nicholas Eminizer, Christian Schnaible, Jonathan Fulcher, Anatoli Pashenkov, Avto Kharchilava, Mikhail Ignatenko, Tapio Lampén, Manfred Paulini, Jessica Prisciandaro, Pierluigi Bortignon, Matthias Kasemann, Cole Lindsey, Daniele Ruini, Michail Bachtis, Claudia Cecchi, Norraphat Srimanobhas, Dermot Moran, Ugo Gasparini, Veikko Karimäki, Paola Salvini, Florian Beaudette, Bennett Marsh, Duncan Carlsmith, Jeremie Alexandre Merlin, Piotr Zalewski, Sara Fiorendi, Daniel Arcaro, Marek Walczak, Xinmei Niu, Dragos Velicanu, Vasken Hagopian, G. M. Dallavalle, Bhargav Madhusudan Joshi, Georgios Krintiras, Andrea Gelmi, Qamar Hassan, Nuno Leonardo, Bora Akgun, Mariana Araujo, Matteo Presilla, Zeynep Demiragli, Marina Kolosova, Yalcin Guler, Ashutosh Bhardwaj, Roger Wolf, Kelly Beernaert, Luigi Guiducci, Gregory R Snow, Lev Dudko, Jeremy Andrea, Marta Verweij, Igor Volobouev, Özlem Özçelik, Peter Raics, Peicho Petkov, Leonardo Cristella, Achille Petrilli, Chun-Hua Jiang, Hong Ni, W. T. Ford, P. J. Fernández Manteca, Luca Guzzi, Pierluigi Zotto, Hwi Dong Yoo, Sushil Chauhan, Kajari Mazumdar, Nickolas Mccoll, Robert Bainbridge, Gobinda Majumder, H. Rejeb Sfar, Jane Nachtman, R. Gonzalez Suarez, Sergio F Novaes, Samet Lezki, Morgan Lethuillier, Yasar Onel, Marcus Hohlmann, Amedeo Staiano, Sharad Malik, Carlos Florez, Ignacio Redondo, Benjamin Stieger, Nicolas Postiau, Marco Musich, Yurii Maravin, Vladimir Gavrilov, H. Sert, Hongbo Liao, Aleko Khukhunaishvili, Stefano Marcellini, Sonaina Undleeb, Spandan Mondal, A. C. Le Bihan, R. M. Brown, Hannes Jung, Mark Saunders, Alexander Zhokin, Martijn Mulders, A. Rose, S. Kaur, A. Bragagnolo, Song-Ming Wang, Kamal Lamichhane, Mary Hadley, Martino Margoni, Navid Rad, Yagya Raj Joshi, Susan Gascon, Gunther Roland, K. El Morabit, Ji Hwan Bhyun, Illia Khvastunov, Lea Caminada, Rong-Shyang Lu, Simon Regnard, Jiajing Mao, Leonid Levchuk, B. Penning, Luca Scodellaro, Christos Roskas, Maria Cepeda, Jorgen D'Hondt, Davide Piccolo, T. Mitchell, Bahareh Roozbahani, Nadeesha Wickramage, Anna Zanetti, Q. Ingram, L. Valencia Palomo, E. Fontanesi, Paul Avery, Salavat Abdullin, Lisa Benato, Quentin Python, Randy Ruchti, Joe Incandela, Luca Cadamuro, Gregor Kasieczka, Y. Chao, Y. Ershov, Lesya Shchutska, Andrea Massironi, Raffaella Radogna, Markéta Jansová, Francesco Navarria, Sotiroulla Konstantinou, Christopher George Tully, Alexander Belyaev, Claudio Campagnari, Teppo Mäenpää, Stephanie Brandt, R. Mankel, Wolfgang Lohmann, Filip Moortgat, Konstantinos Kousouris, Arne Reimers, Joshua Bendavid, Nicanor Colino, Rostyslav Shevchenko, Patrick Asenov, M. Weber, Aruna Nayak, J. H. Yoo, Gervasio Gomez, A. Delgado Peris, Daniel Salerno, Rohan Bhandari, Vinay Hegde, David Zou, Andrey Korytov, P. Chang, Eduardo De Moraes Gregores, Ashfaq Ahmad, Vladimir Korenkov, Ashim Roy, Andre Frankenthal, Jan Krolikowski, Luiz Mundim, C.-E. Wulz, Duccio Abbaneo, Elizabeth Locci, Ilaria Vai, Cristina Biino, Gabriele Benelli, Patrizia Barria, Somnath Choudhury, L. V. Kardapoltsev, Amitabh Lath, Simon Kudella, Angela Mehta, C. Martinez Rivero, Giorgio Apollinari, Ulf Behrens, M. A. Shah, Charles Mueller, Benjamin Mesic, F. Pandolfi, Teruki Kamon, James Buchanan, Maxim Pieters, A. Di Francesco, Ulrich Heintz, M. Kovac, Bjorn Burkle, N. Vanegas Arbelaez, Erhan Gülmez, Kaori Maeshima, Martin Erdmann, Andrew Wisecarver, Jim Hanlon, D. Soldi, Patricia McBride, Krzysztof Doroba, Dylan Rankin, Andrew Brinkerhoff, Thomas Ferguson, Jose Flix, S. Sánchez Navas, Didier Contardo, Jose Chinellato, Richard Cavanaugh, Ivan Pozdnyakov, Ruchi Chudasama, Marco Rovere, Marco Toliman Lucchini, Mauricio Thiel, Alexis Pompili, Abraham Tishelman-Charny, Ilya Gorbunov, Peter Timothy Cox, Torben Lange, Michael Mulhearn, Stephen Wimpenny, Henning Flacher, Nikolaos Manthos, Christian Laner, Martin Grunewald, Ilya Kravchenko, Jeroen Hegeman, J. Piedra Gomez, Wolfram Erdmann, Maria Teresa Grippo, Rajat Gupta, Anatoli Zarubin, O. Zenaiev, James Wetzel, S. Seif El Nasr-storey, Mara Senghi Soares, Serguei Ganjour, Silvia Taroni, Maria Giulia Ratti, Daniel Pitzl, Darien Wood, Joaquin Emilo Siado, Maksat Haytmyradov, Paolo Montagna, Thomas Berger, J. Madhusudanan Sreekala, Othmane Bouhali, Milan Stojanovic, Jyothsna Rani Komaragiri, Ian Watson, Nicholas John Hadley, Jehad Mousa, Carlos Erice, Karl Matthew Ecklund, H. Zhang, David Mason, Luigi Moroni, Luca Lista, L. R. Sulak, M. A. Segura Delgado, A. Rizzi, Maral Alyari, A. Richards, Samandeep Sharma, He He, David Krofcheck, J. P. Fernández Ramos, S. Gianì, Andrew Evans, Roberto Leonardi, Alexander Barnyakov, Markus Merschmeyer, Eduardo Coelho, Ozlem Kaya, Sevil Salur, Y. Wang, Duje Giljanovic, Markus Stoye, C. Wissing, A. Castaneda Hernandez, B. McMaster, Fan Xia, Dietrich Liko, Mykhailo Dalchenko, Alain Hervé, Yuri Skovpen, Jingyu Luo, Prafulla Kumar Behera, Riccardo Andrea Manzoni, Christian Veelken, Yu. Andreev, Markus Klute, A. Di Mattia, Ivan Vila, S. Carrillo Moreno, Joel Goldstein, Luciano Ristori, Milena Misheva, Luigi Calligaris, Kevin Pedro, Silvano Tosi, Ryan Heller, Maxime Guilbaud, Daniel Treille, William John Womersley, Kelvin Mei, S. R. Dugad, D. De Jesus Damiao, A. Moraes, Tomas Lindén, Tamas Novak, N. Van Remortel, Alice Florent, Fabio Iemmi, German Martinez, T. Susa, Cristina Botta, Viesturs Veckalns, Dario Bisello, Pascal Paganini, R. Walsh, G. P. Siroli, Jonas Rembser, S. Zhang, Andrea Triossi, Christoph Schwick, M. Aguilar-Benitez, J. Vaitkus, V. Myronenko, Simone Gennai, Bibhuprasad Mahakud, G. Gomez Ceballos, Nikos Varelas, Helen F Heath, Joshua Hiltbrand, J. Choi, Kenichi Hatakeyama, Anna Woodard, Petr Levchenko, Nikolai Golubev, D. R. Claes, Marcel Rieger, Anders Ryd, Gavin Davies, M. Voutilainen, Alexander Lanev, T. Kress, Susan Dittmer, Kalyanmoy Chatterjee, Georgios Daskalakis, Sergei Gninenko, J. C. Freeman, Petr Mandrik, M. Shi, Senka Duric, Benjamin Tannenwald, Guler Karapinar, S. Petrushanko, Samuel May, Giuseppe Latino, Matthew Kilpatrick, Alessandro Giassi, Süleyman Durgut, John Paul Chou, Rishabh Uniyal, Brian Paul Padley, Justin Williams, Zhaozhong Shi, Nairit Sur, Gregory Iles, C. F. González Hernández, Seth Cooper, Semra Turkcapar, Linda Finco, Mingshui Chen, Matthias Komm, Arnab Purohit, Simona Cometti, Scott Thomas, S. W. Lee, J. D. Richman, Yannik Rath, Predrag Cirkovic, Viola Sordini, Erika Garutti, Giancarlo Mantovani, Carlo Battilana, Sezen Sekmen, Z. Liu, Inseok Yoon, S. Consuegra Rodríguez, K. Osterberg, Maximilian Heindl, Alexander Savin, M. Finger, F. Mohamad Idris, and Malte Backhaus
Subjects: Physics, Nuclear and High Energy Physics, Gluino, Particle physics, Luminosity (scattering theory), Large Hadron Collider, Proton, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Superpartner, Supersymmetry, 01 natural sciences, Supersymmetry breaking, Particle identification, 0103 physical sciences, ddc:530, High Energy Physics::Experiment, 010306 general physics
Abstract: A search for long-lived particles decaying to displaced, nonprompt jets and missing transverse momentum is presented. The data sample corresponds to an integrated luminosity of 137fb−1 of proton-proton collisions at a center-of-mass energy of 13TeV collected by the CMS experiment at the CERN LHC in 2016–2018. Candidate signal events containing nonprompt jets are identified using the timing capabilities of the CMS electromagnetic calorimeter. The results of the search are consistent with the background prediction and are interpreted using a gauge-mediated supersymmetry breaking reference model with a gluino next-to-lightest supersymmetric particle. In this model, gluino masses up to 2100, 2500, and 1900GeV are excluded at 95% confidence level for proper decay lengths of 0.3, 1, and 100m, respectively. These are the best limits to date for such massive gluinos with proper decay lengths greater than ∼0.5m.
Published: 2019

45. Orbital cholesterol granuloma: A report and discussion of orbital findings

Author: Sander R. Dubovy, Bradford W. Lee, Benjamin P. Erickson, Andrew J. Rong, and Nathan W. Blessing
Subjects: Xanthomatosis of the orbit, Pathology, medicine.medical_specialty, genetic structures, Hematocele, Lacrimal gland, Article, Lesion, 03 medical and health sciences, 0302 clinical medicine, Orbitofrontal choletesterol granuloma, Ptosis, lcsh:Ophthalmology, Medicine, Cholesteatoma, Cholesterol Cleft, business.industry, medicine.disease, Hematic cyst, eye diseases, Blood cyst, Ophthalmology, medicine.anatomical_structure, lcsh:RE1-994, 030221 ophthalmology & optometry, sense organs, medicine.symptom, Differential diagnosis, business, 030217 neurology & neurosurgery, Orbit (anatomy)
Abstract: Purpose: To report a case of orbital cholesterol granuloma and discuss the orbital findings seen in this entity. Observation: A 38-year-old male presented with an 8-month history of progressive left upper lid ptosis and hypoglobus. Clinical examination was significant for 3 mm of hypoglobus and restricted supraduction in the left eye. Contrasted computed tomography imaging revealed a well-circumscribed lesion in the superotemporal orbit causing extensive bone erosion that appeared to arise from the lacrimal gland. An incisional biopsy was performed, and histopathological evaluation demonstrated fibrovascular tissue surrounding a mixture of histiocytes and cholesterol clefts, consistent with a cholesterol granuloma. Conclusions and importance: Orbital cholesterol granulomas are rare lesions that are predominantly found in the superotemporal orbit. These lesions can be associated with marked bony changes in the superotemporal fossa that can be mistaken for a lacrimal gland neoplasm; however, bony erosion is a hallmark of this lesion and should be considered on the differential diagnosis of any lacrimal gland mass with extensive bony erosion. Keywords: Blood cyst, Hematocele, Xanthomatosis of the orbit, Cholesteatoma, Hematic cyst, Orbitofrontal choletesterol granuloma
Published: 2019

46. List of Contributors

Author: Cristina S. Albott, Rajagopal N. Aravalli, Dawn Bardot, Michael G. Bateman, Jazmin Camchong, Mo Chen, Wei Chen, Christopher C. Cline, Andrew Crane, Georgette Danczyk, Federico De Martino, William K. Durfee, Michael D. Eggen, Arthur G. Erdman, Kate L. Frost, Erik N. Gaasedelen, Bernadette T. Gillick, Noam Harel, Bin He, Mikayle A. Holm, Rebecca A. Hortensius, Brian T. Howard, Stephen J. Huddleston, Paul A. Iaizzo, Tinen L. Iles, Ranjit John, Rosemary F. Kelly, Natalie Kerns, Teresa J. Kimberley, Kanchan Kulkarni, Steven W. Lee, Christophe Lenglet, Kenneth K. Liao, Kelvin O. Lim, Wei-Han Lin, Walter C. Low, Ming Lu, Wei-Cheng Lu, Lars M. Mattison, Alexander R. Mattson, Zachary D. Miller, Teerapat Nantsupawat, Samuel T. Nemanich, Theoden I. Netoff, Anh Tuan Nguyen, Brenda M. Ogle, Matthew Olson, Remi Patriat, Clairice Pearce, Cecilia N. Prudente, Henri Roukoz, Abhrajeet V. Roy, Jorge D. Zhingre Sanchez, Neeraj Sathnur, Randy Schiestl, Andrew W. Shaffer, Maple Shiao, Christopher Sipe, John R. Spratt, Clifford J. Steer, Elena G. Tolkacheva, Nikolas G. Toman, Kamil Ugurbil, Jerrold L. Vitek, Joseph Voth, Hui Xie, Jian Xu, Essa Yacoub, Zhi Yang, and Xiao-Hong Zhu
Published: 2019

47. Benchtop Optical Mapping Approaches to Study Arrhythmias

Author: Kanchan Kulkarni, Elena G. Tolkacheva, and Steven W. Lee
Subjects: medicine.medical_specialty, genetic structures, Cardiac electrophysiology, business.industry, Ventricular tachycardia, medicine.disease, eye diseases, Nerve conduction velocity, Electrophysiology, Internal medicine, Optical mapping, Ventricular fibrillation, cardiovascular system, medicine, Cardiology, Repolarization, Action potential duration, business
Abstract: This chapter offers an overview of optical mapping concepts and provides details related to various applications of this technique to visualize the normal and abnormal rhythms of the heart. It enables the visualization of activation propagation and determination of relative conduction velocity of electrical activity of the heart and can be used to assess action potential duration at various levels of repolarization. Optical mapping can also be utilized to visualize different types of arrhythmias in the heart, such as ventricular tachycardia and ventricular fibrillation. This technique has been widely employed to visualize, predict, and control the onset of abnormal cardiac rhythms such as alternans. Optical mapping can also be beneficial in studying acute changes in cardiac electrophysiological properties of the heart during various disease states and also to develop and evaluate therapeutic strategies.
Published: 2019

48. TOXICOLOGY | Interpretation of Results

Author: Hearn, W Lee, primary
Published: 2000
Full Text: View/download PDF

49. Traumatic rupture of an ovarian teratoma – Case report and review of the literature

Author: Avital Yohann, Saleem Islam, and Constance W. Lee
Subjects: medicine.medical_specialty, endocrine system, 030219 obstetrics & reproductive medicine, endocrine system diseases, business.industry, fungi, lcsh:RJ1-570, lcsh:Surgery, food and beverages, 030208 emergency & critical care medicine, lcsh:Pediatrics, lcsh:RD1-811, female genital diseases and pregnancy complications, Surgery, 03 medical and health sciences, 0302 clinical medicine, Pediatrics, Perinatology and Child Health, Medicine, Ovarian Teratoma, medicine.symptom, business, Free fluid, Confusion
Abstract: Traumatic rupture of a cystic ovarian teratoma is extremely rare and has not been reported in a child. The free fluid can lead to diagnostic confusion for a ruptured viscus.
Published: 2017

50. List of Contributors

Author: Ramzi M. Alameddine, Mathew M. Avram, Daniel C. Baker, Dewayne T. Bradley, Andrew Breithaupt, César A. Briceño, Jeannie H. Chung, Victor Chung, Sebastian Cotofana, Patricia K. Farris, Jill Foster, John W. Frederick, Alvin I. Glasgold, Mark J. Glasgold, Robert A. Glasgold, Shani Golan, Robert Goldberg, Carlo P. Honrado, Catherine J. Hwang, Andrew A. Jacono, H. Ray Jalian, Michael Kane, Gregory S. Keller, Don O. Kikkawa, Bobby S. Korn, Andrea Lora Kossler, Samuel M. Lam, Wayne F. Larrabee, Bradford W. Lee, Steven M. Levine, Wei Lu, Melanie H. Malone, Hyoung Jin Moon, Vishad Nabili, Joe Niamtu, Oscar M. Ramirez, Neela Rao, David B. Samimi, Daniel Straka, Gustavo A. Suárez, Jonathan M. Sykes, Dean M. Toriumi, Patrick Trevidic, Charles R. Volpe, and Edwin F. Williams
Published: 2018

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