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Your search keyword '"Vincenzo Castiglione"' showing total 6 results
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6 results on '"Vincenzo Castiglione"'

1. Biopsy Evidence of Sequential Transthyretin and Immunoglobulin Light-Chain Cardiac Amyloidosis in the Same Patient

Author

Giuseppe Vergaro, MD, PhD, Vincenzo Castiglione, MD, Roberta Poletti, MD, Gabriele Buda, MD, Angela Pucci, MD, PhD, Veronica Musetti, BSc, Dario Genovesi, MD, Alberto Aimo, MD, Claudio Passino, MD, and Michele Emdin, MD, PhD

Subjects
AL amyloidosis, ATTR amyloidosis, cardiac amyloidosis, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Currently adopted diagnostic flow charts consider transthyretin and light-chain cardiac amyloidosis as mutually exclusive. Here, we report for the first time, to our knowledge, the demonstration of a biopsy-proven dual pathology in an 80-year-old man with sequential development of both wild-type transthyretin amyloidosis and light-chain cardiac amyloidosis cardiomyopathy over a 3-year timespan. (Level of Difficulty: Intermediate.)

Published
2021
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2. Scared to Death

Author

Alberto Aimo, MD, Marco Di Paolo, MD, Vincenzo Castiglione, MD, Martina Modena, BS, Andrea Barison, MD, PhD, Matteo Benvenuti, MD, Valentina Bugelli, MD, Carlo Pietro Campobasso, MD, Benedetta Guidi, MD, Paolo G. Camici, MD, PhD, and Michele Emdin, MD, PhD

Subjects
emotional stress, forensic examination, MINOCA, myocardial infarction, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Myocardial infarction with nonobstructed coronary arteries (MINOCA) can be triggered by intense emotions. We report 5 cases of emotional stress–related death where forensic examination attributed myocardial infarction to a coronary spasm, with the ultimate cause of death being arrhythmias in 4 cases and cardiac rupture in the fifth. (Level of Difficulty: Beginner.)

Published
2020
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3. Safety and Efficacy of Amiodarone in a Patient With COVID-19

Author

Nadia Castaldo, MD, Alberto Aimo, MD, Vincenzo Castiglione, MD, Cristiano Padalino, MD, Michele Emdin, MD, PhD, and Carlo Tascini, MD, PhD

Subjects
amiodarone, COVID-19, SARS-CoV-2, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

There is an urgent need for effective treatments for coronavirus disease-2019 (COVID-19). Amiodarone, like hydroxychloroquine, exerts antiviral actions by interfering with endocytosis and viral replication. Here, to our knowledge, we report the first case of a patient affected by respiratory failure related to COVID-19 who recovered after only supportive measures and a short amiodarone course. (Level of Difficulty: Beginner.)

Published
2020
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4. What Is Hidden Behind Inferior Negative T Waves

Author

Vincenzo Castiglione, MD, Alberto Aimo, MD, Bruno Murzi, MD, Angela Pucci, MD, PhD, Giovanni Donato Aquaro, MD, Andrea Barison, MD, PhD, Alberto Clemente, MD, Valentina Spini, MD, Giovanni Benedetti, MD, and Michele Emdin, MD, PhD

Subjects
cardiac mass, cardiac tumor, glomangioma, glomus tumor, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Negative T waves in the inferior leads in an asymptomatic 17-year-old female patient prompted a diagnostic evaluation disclosing the presence of multiple cardiac glomangiomas. The combination of different imaging modalities (echocardiography, magnetic resonance, and positron emission tomography/computed tomography) and myocardial biopsy was crucial to establishing the correct diagnosis. (Level of Difficulty: Advanced.)

Published
2019
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5. Biopsy Evidence of Sequential Transthyretin and Immunoglobulin Light-Chain Cardiac Amyloidosis in the Same Patient

Author

Michele Emdin, Gabriele Buda, Angela Pucci, Vincenzo Castiglione, Alberto Aimo, Veronica Musetti, Dario Genovesi, Claudio Passino, Roberta Poletti, and Giuseppe Vergaro

Subjects
0301 basic medicine, Pathology, medicine.medical_specialty, hs-cTnT, high-sensitivity cardiac troponin T, Cardiomyopathy, 99mTc-HMDP, 99mTc-hydroxymethylene diphosphonate, 030105 genetics & heredity, Immunoglobulin light chain, Mutually exclusive events, HF, heart failure, 03 medical and health sciences, 0302 clinical medicine, CMR, cardiac magnetic resonance, Biopsy, LVEF, left ventricular ejection fraction, medicine, AL amyloidosis, ATTR amyloidosis, Diseases of the circulatory (Cardiovascular) system, LV, left ventricular, CA, cardiac amyloidosis, ATTR, transthyretin amyloidosis, biology, medicine.diagnostic_test, business.industry, Amyloidosis, AL, immunoglobulin light-chain amyloidosis, cardiac amyloidosis, Mini-Focus Issue: Heart Failure, medicine.disease, Ig, immunoglobulin, Transthyretin, Cardiac amyloidosis, RC666-701, biology.protein, NT-proBNP, N-terminal pro–B-type natriuretic peptide, Case Report: Clinical Case, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery
Abstract

Currently adopted diagnostic flow charts consider transthyretin and light-chain cardiac amyloidosis as mutually exclusive. Here, we report for the first time, to our knowledge, the demonstration of a biopsy-proven dual pathology in an 80-year-old man with sequential development of both wild-type transthyretin amyloidosis and light-chain cardiac amyloidosis cardiomyopathy over a 3-year timespan. (Level of Difficulty: Intermediate.), Graphical abstract

Published
2021

6. Scared to Death

Author

Vincenzo Castiglione, Matteo Benvenuti, Michele Emdin, Benedetta Guidi, Marco Di Paolo, Paolo G. Camici, Martina Modena, Valentina Bugelli, Carlo Pietro Campobasso, Alberto Aimo, and Andrea Barison

Subjects
0301 basic medicine, medicine.medical_specialty, Mini-Focus Issue: Interventions, Case Report: Clinical Case Series, 030105 genetics & heredity, hs-TnT, high-sensitivity troponin T, 03 medical and health sciences, 0302 clinical medicine, MINOCA, myocardial infarction with nonobstructed coronary arteries, Internal medicine, Medicine, Diseases of the circulatory (Cardiovascular) system, Myocardial infarction, cardiovascular diseases, forensic examination, Forensic examination, LV, left ventricular, MI - Myocardial infarction, emotional stress, MINOCA, business.industry, food and beverages, Emotional stress, medicine.disease, Coronary arteries, medicine.anatomical_structure, myocardial infarction, RC666-701, Cardiology, cardiovascular system, MI, myocardial infarction, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery
Abstract

Myocardial infarction with nonobstructed coronary arteries (MINOCA) can be triggered by intense emotions. We report 5 cases of emotional stress–related death where forensic examination attributed myocardial infarction to a coronary spasm, with the ultimate cause of death being arrhythmias in 4 cases and cardiac rupture in the fifth. (Level of Difficulty: Beginner.), Graphical abstract, Myocardial infarction with nonobstructed coronary arteries (MINOCA) can be triggered by intense emotions. We report 5 cases of emotional…

Published
2020

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