28 results on '"Thomas B Nutman"'
Search Results
2. Ivermectin
- Author
-
Philip J. Cooper and Thomas B. Nutman
- Published
- 2020
3. Onchocerciasis
- Author
-
Thomas B. Nutman
- Published
- 2020
4. Serological evaluation of onchocerciasis and lymphatic filariasis elimination in the Bakoye and Falémé foci, Mali
- Author
-
Michel Emmanuel Coulibaly, Lamine Soumaoro, M. Dembele, Robert Colebunders, María-Gloria Basáñez, M. Sow, Moussa Brema Sangare, Thomas B. Nutman, Yaya Ibrahim Coulibaly, Salif S. Doumbia, Martin Walker, Housseini Dolo, Siaka Y. Coulibaly, Ilo Dicko, and Abdallah A. Diallo
- Subjects
Microbiology (medical) ,Pathology ,medicine.medical_specialty ,business.industry ,General Medicine ,medicine.disease ,Serology ,lcsh:Infectious and parasitic diseases ,Infectious Diseases ,medicine ,lcsh:RC109-216 ,business ,Onchocerciasis ,Lymphatic filariasis - Published
- 2020
5. Immune Responses to Helminth Infection
- Author
-
Subash Babu and Thomas B. Nutman
- Subjects
Cell type ,Immune system ,Helminth infections ,Antibody response ,medicine.anatomical_structure ,parasitic diseases ,Usually fatal ,Immunology ,Innate lymphoid cell ,medicine ,Helminths ,Eosinophil ,Biology - Abstract
Over 2 billion people worldwide are infected with helminths (worms). Helminth infections are a major public health problem worldwide due to their ability to cause significant morbidity and socioeconomic loss. Although not usually fatal, helminth infections induce a spectrum of pathological responses (with ensuing clinical manifestations) resulting in major morbidity in helminth - afflicted individuals. The immune response to helminths typically involves Type 2 responses (encompassing Th2, Type 2 innate lymphoid cell, eosinophil and antibody responses) and regulatory responses (encompassing regulatory cytokines and cellular subsets). In this chapter, we discuss recent advances in defining the immune cell types and molecules that are induced by helminth infections. We also report on the modulation of immune responses that enables the establishment of long-standing or persistent infection and its major mediators.
- Published
- 2019
6. List of Contributors
- Author
-
Roshini Sarah Abraham, Cristina Albanesi, Ilias Alevizos, Juan Anguita, Brendan Antiochos, Cynthia Aranow, John P. Atkinson, Howard A. Austin, Subash Babu, Mark C. Ballow, James E. Balow, John W. Belmont, Claudia Berek, Timothy Beukelman, Tapan Bhavsar, J. Andrew Bird, Sarah E. Blutt, Mark Boguniewicz, Rafael Bonamichi-Santos, Bertrand Boisson, Elena Borzova, Prosper N. Boyaka, Joshua Boyce, Sarah K. Browne, Wesley Burks, Jacinta Bustamante, Virginia L. Calder, Matthew Campbell, Adela Rambi G. Cardones, Jean-Laurent Casanova, Mariana Castells, Lisa A. Cavacini, Edwin S.L. Chan, David D. Chaplin, W. Winn Chatham, Edward S. Chen, Javier Chinen, Lisa Christopher-Stine, Michael Ciancanelli, Andrew P. Cope, David B. Corry, Filippo Crea, Randy Q. Cron, Jennifer M. Cuellar-Rodriguez, Marinos C. Dalakas, Sara M. Dann, Betty Diamond, Terry W. Du, Stéphanie Dupuis-Boisson, Todd N. Eagar, Craig A. Elmets, Doruk Erkan, Laura Fanning, Erol Fikrig, Davide Flego, Thomas A. Fleisher, Luz Fonacier, Andrew P. Fontenot, Alexandra F. Freeman, Anthony J. Frew, Kohtaro Fujihashi, Massimo Gadina, Moshe E. Gatt, M. Eric Gershwin, Susan L. Gillespie, Jörg J. Goronzy, Sangeeta Goswami, Clive E.H. Grattan, Neil S. Greenspan, Sarthak Gupta, Claire E. Gustafson, Russell P. Hall, Robert G. Hamilton, Laurie E. Harrington, Leonard C. Harrison, Sarfaraz A. Hasni, Arthur Helbling, Joanna Hester, Steven M. Holland, Dennis Hourcade, Nicholas D. Huntington, Tracy Hwangpo, John B. Imboden, Fadi Issa, Shai Izraeli, Elaine S. Jaffe, Sirpa Jalkanen, Stacie Jones, Emmanuelle Jouanguy, Sarah Kabbani, Stefan H.E. Kaufmann, Farrah Kheradmand, Donald B. Kohn, Robert Korngold, Anna Kovalszki, Douglas B. Kuhns, Hrishikesh Kulkarni, Caroline Y. Kuo, Arash Lahouti, C. Ola Landgren, Arian Laurence, Joyce S. Lee, Catherine Lemière, Donald Y.M. Leung, Arnold I. Levinson, Ofer Levy, Dorothy E. Lewis, Phoebe Lin, Andreas Linkermann, Giovanna Liuzzo, Michael D. Lockshin, Allison K. Lord, Jay N. Lozier, Amber Luong, Raashid Luqmani, Meggan Mackay, Jonathan S. Maltzman, Peter J. Mannon, Michael P. Manns, James G. Martin, Craig L. Maynard, Samual McCash, Douglas R. McDonald, Peter C. Melby, Stephen D. Miller, Anna L. Mitchell, Amirah Mohd-Zaki, Carolyn Mold, David R. Moller, Dimitrios S. Monos, Scott N. Mueller, Catharina M. Mulders-Manders, Mark J. Mulligan, Ulrich R. Müller, Pashna N. Munshi, Kazunori Murata, Philip M. Murphy, Nicolás Navasa, Pierre Noel, Luigi D. Notarangelo, Robert L. Nussbaum, Thomas B. Nutman, Stephen L. Nutt, João B. Oliveira, Thomas L. Ortel, John J. O'Shea, Sung-Yun Pai, Lavannya Pandit, Mary E. Paul, Simon H.S. Pearce, Daniela Pedicino, Erik J. Peterson, Capucine Picard, Stefania Pittaluga, Debra Long Priel, Jennifer Puck, Anne Puel, Andreas Radbruch, Stephen T. Reece, John D. Reveille, Robert R. Rich, Chaim M. Roifman, Antony Rosen, James T. Rosenbaum, Sergio D. Rosenzweig, Barry T. Rouse, Scott D. Rowley, Shimon Sakaguchi, Marko Salmi, Andrea J. Sant, Sarah W. Satola, Valerie Saw, Marcos C. Schechter, Harry W. Schroeder, Benjamin M. Segal, Carlo Selmi, Sushma Shankar, Anu Sharma, Padmanee Sharma, William T. Shearer, Richard M. Siegel, Anna Simon, Gideon P. Smith, David S. Stephens, Robin Stephens, Alex Straumann, Leyla Y. Teos, Laura Timares, Wulf Tonnus, Raul M. Torres, Gülbü Uzel, Jeroen C.H. van der Hilst, Jos W.M. van der Meer, John Varga, Jatin M. Vyas, Meryl Waldman, Peter Weiser, Peter F. Weller, Cornelia M. Weyand, Fredrick M. Wigley, Robert J. Winchester, James B. Wing, Kathryn J. Wood, Xiaobo Wu, Hui Xu, Cassian Yee, and Shen-Ying Zhang
- Published
- 2019
7. List of Contributors
- Author
-
Susan Anderson, Vernon Ansdell, Paul M. Arguin, Howard D. Backer, Jared Baeten, Stephen A. Bezruchka, Micah M. Bhatti, Andrea K. Boggild, Frederick S. Buckner, Connie Celum, Martin S. Cetron, Shireesha Dhanireddy, Julie Dombrowski, Mark Enzler, Charles D. Ericsson, Carey Farquhar, Brian D. Gushulak, James P. Harnisch, N. Jean Haulman, Shevin T. Jacob, Elaine C. Jong, Kevin C. Kain, Andrea Kalus, Edmond Kay, Sarah Kohl, Saba M. Lambert, Anne M. Larson, W. Conrad Liles, Poh Lian Lim, Andrew M. Luks, Sheila M. Mackell, Douglas W. MacPherson, Jeanne M. Marrazzo, Robert Martin, Susan L.F. McClellan, R. Scott McClelland, Anna McDonald, Anne C. Moore, Aliza Monroe-Wise, Masahiro Narita, Michael Noble, Hans Dieter Nothdurft, Thomas B. Nutman, Lucy A. Perrone, Paul S. Pottinger, Camilla Rothe, Christopher A. Sanford, Eli Schwartz, Christopher Spitters, Neil R.H. Stone, Mari C. Sullivan, Kathrine R. Tan, Samuel B. Thielman, Ellen Thompson, Shawn Vasoo, Abinash Virk, Stephen L. Walker, Timothy E. West, Martin S. Wolfe, and Yuan Zhou
- Published
- 2017
8. List of Contributors
- Author
-
Fredrick M. Abrahamian, Michael J. Aldape, Edelweiss Aldasoro, Upton D. Allen, Hythem Al-Sum, Milan J. Anadkat, Katherine Anders, Emmanouil Angelakis, Brian John Angus, Anastasia Antoniadou, Fabio Arena, Joop E. Arends, Jose R. Arribas, Andrew W. Artenstein, John C. Atherton, John N. Aucott, Tar-Ching Aw, Hilary M. Babcock, Robin Bailey, Thomas C. Bailey, Adam Z. Banks, David J. Barillo, Ernie-Paul Barrette, Martijn P. Bauer, Roger Bayston, C. Ben Beard, Justin Beardsley, Nick J. Beeching, Rodolfo E. Bégué, Guido Beldi, Constance A. Benson, Elie F. Berbari, Jean-Michel Berenger, Christoph Berger, Jose I. Bernardino, Jacques Bille, Alexander C. Billioux, Ari Bitnun, Iain Blair, Stéphane Blanche, Thomas P. Bleck, Chantal P. Bleeker-Rovers, Gijs Bleijenberg, Karen C. Bloch, Johannes Blum, Emily A. Blumberg, Robert A. Bonomo, Marc J.M. Bonten, Rafik Bourayou, Emilio Bouza, K. Ashley Brandt, Florence Bretelle, Sylvain Brisse, Warwick J. Britton, Itzhak Brook, Matthijs C. Brouwer, Sarah K. Browne, Amy E. Bryant, Silja Bühler, Eileen M. Bulger, R. Mark L. Buller, Leah A. Burke, Christian Burri, Marcus W. Butler, Thierry Calandra, David P. Calfee, Antonia Calvo-Cano, D. William Cameron, Joseph A. Carcillo, Gail Carson, Stephen T. Chambers, Remi N. Charrel, Vinh Chau Van Nguyen, Stéphane Chevaliez, Tom M. Chiller, Eirini Christaki, Kevin K. Chung, David B. Clifford, Nathan Clumeck, Jonathan Cohen, John Collinge, Christopher P. Conlon, Curdin Conrad, Fiona J. Cooke, Jennifer Rittenhouse Cope, G. Ralph Corey, John H. Cross, Burke A. Cunha, Cheston B. Cunha, Benoit D'Journo, George L. Daikos, Johannes M.A. Daniels, Robert N. Davidson, Nicholas P.J. Day, Kevin M. De Cock, Thushan I. de Silva, Henry J.C. de Vries, Stéphane de Wit, Julie Delaloye, David W. Denning, David T. Dennis, Shireesha Dhanireddy, Elodi J. Dielubanza, David J. Diemert, Mehmet Doganay, Tom Doherty, Christiane Dolecek, Arjen M. Dondorp, Abby Douglas, Michel Drancourt, Grégory Dubourg, Michael N. Dudley, Guillaume Durand, Benjamin J. Eckhardt, Androulla Efstratiou, Miquel B. Ekkelenkamp, Ambika Eranki, Hakan Erdem, Gerome V. Escota, Heather L. Evans, Alice Chijioke Eziefula, Florence Fenollar, Alan Fenwick, Joshua Fierer, Roger G. Finch, James M. Fleckenstein, Christina Forstner, Federico Foschi, Pierre-Edouard Fournier, Martyn A. French, Kenneth L. Gage, Lynne S. Garcia, Joaquim Gascon, Arturo S. Gastañaduy, Philippe Gautret, William M. Geisler, Khalil G. Ghanem, Tommaso Giani, Maddalena Giannella, Bruce L. Gilliam, Michel Gilliet, Carol A. Glaser, Youri Glupczynski, John W. Gnann, Ellie J.C. Goldstein, Bruno Gottstein, Frederique Gouriet, Patti E. Gravitt, Michael D. Green, Stephen T. Green, Andreas H. Groll, Roy M. Gulick, Arjun Gupta, Gilbert Habib, Stephan Harbarth, Marianne Harris, Frederick G. Hayden, David J. Hetem, Philip C. Hill, Bernard Hirschel, Aimee C. Hodowanec, Louis Hoffart, Christian Hoffmann, Steven M. Holland, Peter W. Horby, David J. Horne, Sami Hraiech, Mark W. Hull, Angela Huttner, Richard J.M. Ingram, Jasmin Islam, Michael G. Ison, Scott H. James, Claire Jenkins, Stephen G. Jenkins, Jørgen Skov Jensen, Christine Johnston, Theodore B. Jones, Stephen J. Jordan, Kathleen G. Julian, Yasuyuki Kato, Carol A. Kauffman, Keith S. Kaye, Michael P. Keane, James Keeney, Paul Kelly, Stephen J. Kent, Winfried V. Kern, Yoav Keynan, Andrea A. Kim, Isabelle Koné-Paut, Chris Kosmidis, Aloys C.M. Kroes, Frank P. Kroon, Thomas G. Ksiazek, F. Matthew Kuhlmann, Ed J. Kuijper, Jennie H. Kwon, George B. Kyei, Karine Lacombe, Philippe Lagacé-Wiens, Jean-Christophe Lagier, Theresa Lamagni, Luce Landraud, Fanny Lanternier, Kerry L. LaPlante, Stephen D. Lawn, Steven J. Lawrence, Hakan Leblebicioglu, Nelson Lee, James E. Leggett, Philippe Lehours, Pierre-Yves Levy, Rainer G. Leyh, Rebecca A. Lillis, Direk Limmathurotsakul, Jennifer Lin, H.D. Alan Lindquist, Benjamin A. Lipsky, Christina Liscynesky, David Looney, Olivier Lortholary, Franklin D. Lowy, Benjamin J. Luft, Philip A. Mackowiak, Paul A. MacPherson, Valérie Maghraoui-Slim, Patrick W. Mallon, Julie E. Mangino, Oriol Manuel, Oscar Marchetti, Kristen M. Marks, Kieren A. Marr, Jeanne Marrazzo, Jonas Marschall, David H. Martin, Frédéric Matonti, Richard S. Matulewicz, Kenneth H. Mayer, Russell J. McCulloh, Rose McGready, Rennatus Mdodo, Simon Mead, Francis Mégraud, Graeme Meintjes, Sarah C. Metcalf, Marian G. Michaels, Giovanni Battista Migliori, Michael A. Miles, Alastair Miller, Matthew J. Mimiaga, Marie-Paule Mingeot-Leclercq, Elizabeth Ann Misch, Makedonka Mitreva, Julio S.G. Montaner, Caroline B. Moore, Patricia Muñoz, Jose Muñoz, Clinton K. Murray, Didier Musso, Mable Mutengo, Misha M. Mutizwa, Kurt G. Naber, Pavithra Natarajan, Santiago Neme, Paul N. Newton, Ronald A. Nichols, Lindsay E. Nicolle, François Nosten, Luigi D. Notarangelo, Thomas B. Nutman, Paul Nyirjesy, P. Ronan O'Connell, Steven M. Opal, L. Peter Ormerod, Douglas R. Osmon, Marie Boulze Pankert, Giuseppe Pantaleo, Laurent Papazian, Diane M. Parente, Philippe Parola, Shadi Parsaei, Manuel A. Pascual, Rupa Patel, Eleni Patrozou, Jean-Michel Pawlotsky, Sharon J. Peacock, Jean-Claude Pechère, Ivan Pelegrin, Barry S. Peters, Edgar J.G. Peters, Jeannine M. Petersen, Lyle R. Petersen, Vidmantas Petraitis, Luu-Ly Pham, Albert Picado, Adrian Pilatz, Benoit Pilmis, María-Jesús Pinazo, Mathias W. Pletz, Jason M. Pogue, Evelyn L. Polgreen, Philip M. Polgreen, Klara M. Posfay-Barbe, William G. Powderly, Rachel Presti, Guy Prod'hom, Mirja Puolakkainen, Thomas C. Quinn, Didier Raoult, Raymund R. Razonable, Robert C. Read, Robert R. Redfield, Rob J. Rentenaar, Steven J. Reynolds, Camillo Ribi, Malcolm D. Richardson, Michele L. Ritter, Antoine Roch, Jürgen Kurt Rockstroh, Amanda Rojek, José R. Romero, Suzan H.M. Rooijakkers, Daniel Rosenbluth, Sergio D. Rosenzweig, Gian Maria Rossolini, Ethan Rubinstein, Greg Ryan, Steven A. Safren, Vikrant V. Sahasrabuddhe, Pekka A.I. Saikku, Mohammad M. Sajadi, Michelle R. Salvaggio, Carlos A.Q. Santos, Michael J. Satlin, Anthony J. Schaeffer, Christoph Schimmer, Robert T. Schooley, Richard F. Schumacher, Beverly E. Sha, Daniel S. Shapiro, Gerard Sheehan, David M. Shlaes, Shmuel Shoham, Cameron P. Simmons, Dennis W. Simon, Matthew S. Simon, Kari A. Simonsen, Mary P.E. Slack, Tyrel T. Smith, Jack D. Sobel, Maria Souli, Shruti Sridhar, James M. Steckelberg, Dennis L. Stevens, Heather Strah, A. Willem Sturm, Somnuek Sungkanuparph, Sarah J. Tabrizi, Evelina Tacconelli, Chen Sabrina Tan, Randy A. Taplitz, Guillemette Thomas, Lora D. Thomas, Franck Thuny, Guy Thwaites, Frederic Tissot, Tone Tønjum, Francesca J. Torriani, Christian Toso, Paul M. Tulkens, Allan R. Tunkel, Claire E. Turner, Andrew P. Ustianowski, Françoise van Bambeke, Reinout van Crevel, Diederik van de Beek, Christian van Delden, Menno M. van der Eerden, Jos W.M. van der Meer, Tom van der Poll, Jakko van Ingen, Jos van Putten, Bernard P. Vaudaux, Sten H. Vermund, Raphael P. Viscidi, Kumar Visvanathan, Govinda S. Visvesvara, Lorenz von Seidlein, Florian M.E. Wagenlehner, Anna Wald, Thomas J. Walsh, David C. Warhurst, David W. Warnock, David A. Warrell, Mary J. Warrell, Adilia Warris, Richard R. Watkins, David J. Weatherall, Rainer Weber, Wolfgang Weidner, Jonathan R. White, Peter J. White, James Whitehorn, Richard J. Whitley, Christopher J.M. Whitty, Willem Joost Wiersinga, Mark H. Wilcox, Thomas N. Williams, Cara C. Wilson, Mary Elizabeth Wilson, Hilmar Wisplinghoff, Robin Wood, Richard G. Wunderink, David Wyles, Zhi-Tao Yang, Jonathan S. Yoder, Najam A. Zaidi, Andrea J. Zimmer, Jane N. Zuckerman, and Alimuddin Zumla
- Published
- 2017
9. Vascular Responses in Human Lymphatic Filariasis
- Author
-
Subash Babu and Thomas B. Nutman
- Subjects
Pathology ,medicine.medical_specialty ,Innate immune system ,biology ,medicine.disease ,biology.organism_classification ,medicine.disease_cause ,Brugia malayi ,Lymphangiogenesis ,Lymphedema ,Lymphatic system ,Wuchereria bancrofti ,medicine.anatomical_structure ,Immunology ,medicine ,Lymphatic vessel ,Lymphatic filariasis - Abstract
Although two-thirds of the 120 million people infected with filarial parasites have subclinical infections, ∼40 million have lymphedema and/or other pathologic manifestations including hydroceles (and other forms of urogenital disease), episodic adenolymphangitis, tropical pulmonary eosinophilia, lymphedema, and (in its most severe form) elephantiasis. Filarial parasites reside in the lymphatics and lymph nodes and induce changes that result in dilatation of lymphatics and thickening of the lymphatic vessel walls. Progressive lymphatic damage and pathology ensues and is considered to be the direct summation of multiple factors including the effect of tissue alterations induced by living and dead adult parasites, the host inflammatory response to the parasites and their secreted antigens, the host inflammatory response to the endosymbiont Wolbachia, and those seen as a consequence of secondary bacterial or fungal infections. This review will discuss the proposed mechanisms underlying pathogenesis, including a comprehensive discussion of the changes in the vascular system that underlies host pathology. The data suggest that a complex interaction involving a network of cytokines, vascular growth factors, factors affecting tissue remodeling, and innate immune factors underlies the development of vascular pathology in lymphatic filariasis.
- Published
- 2016
10. List of Contributors
- Author
-
Jacob Al-Hashemi, Salomon Amar, Subash Babu, Edward B. Breitschwerdt, Jerry L. Brunson, Iwona Buskiewicz, Lee Ann Campbell, Han-Oh Chung, Vivian Vasconcelos Costa, Dermot Cox, Danielle da Gloria de Souza, Mahalia S. Desruisseaux, Kelly S. Doran, Tammy R. Dugas, DeLisa Fairweather, Alison E. Fox-Robichaud, Nisha J. Garg, Felicity N.E. Gavins, Mitzi C. Glover, Sally Huber, Mikhail V. Khoretonenko, Jung Hwan Kim, Dorsey L. Kordick, Fabiana S. Machado, Claudia Lucia Martins Silva, Mauro Martins Teixeira, Hema P. Narra, Thomas B. Nutman, Carlos Robello, Bram Rochwerg, Michael E. Rosenfeld, Abha Sahni, Sanjeev K. Sahni, Alexandra Schubert-Unkmeir, Karen Y. Stokes, Herbert B. Tanowitz, Traci L. Testerman, David H. Walker, Jian-jun Wen, and Bryan G. Yipp
- Published
- 2016
11. Immunology of Lymphatic Filariasis
- Author
-
Thomas B. Nutman
- Subjects
Innate immune system ,biology ,T cell ,Elephantiasis ,medicine.disease_cause ,biology.organism_classification ,medicine.disease ,Immunoglobulin E ,Brugia malayi ,Wuchereria bancrofti ,Immune system ,medicine.anatomical_structure ,Immunology ,medicine ,biology.protein ,Lymphatic filariasis - Abstract
The immune responses to filarial parasites encompass a complex network of innate and adaptive cells whose interaction with the parasite underlies a spectrum of clinical manifestations. The predominant immunological feature of lymphatic filariasis (LF) is an antigen-specific T-helper cell 2 (Th2) response and an expansion of IL-10–producing CD4+ T cells that is accompanied by a muted T-helper cell 1 (Th1) response. This antigen-specific T cell hyporesponsiveness appears to be crucial for the maintenance of the sustained, long-standing infection often with high parasite densities. Host immune responses, especially CD4+ T cell responses clearly play a role in mediating pathological manifestations of LF including lymphedema, hydrocele, and elephantiasis.
- Published
- 2016
12. Contributors
- Author
-
David Abraham, Seema S. Aceves, Steven J. Ackerman, Darryl Adamko, Koichi Akashi, Praveen Akuthota, Rafeul Alam, Judith A. Appleton, Narcy Arizmendi, Kewal Asosingh, Keir M. Balla, Christianne Bandeira-Melo, Marc Bartoli, Fleur Samantha Benghiat, Claudia Berek, Utibe Bickham, Elizabeth R. Bivins-Smith, Carine Blanchard, Bruce S. Bochner, Apostolos Bossios, Patricia T. Bozza, David Broide, Miranda Buitenhuis, William W. Busse, Joseph H. Butterfield, Jose A. Cancelas, Monique Capron, Lars Olaf Cardell, Van T. Chu, Michael R. Comeau, Joan M. Cook-Mills, Jan Cools, Olga V. Cravetchi, Benjamin P. Davis, Judah A. Denburg, Joseph B. Domachowske, Virginie Driss, Jian Du, Ann M. Dvorak, Kimberly D. Dyer, Moran Elishmereni, Michael J. Eppihimer, Serpil C. Erzurum, Gary W. Falk, Sophie Fillon, Claudio Fiocchi, Paul S. Foster, Allison D. Fryer, Glenn T. Furuta, Gail M. Gauvreau, Nebiat G. Gebreselassie, Erwin W. Gelfand, Katrin Gentil, Gerald J. Gleich, Pranab Haldar, Noriyasu Hirasawa, Achim Hoerauf, Simon P. Hogan, Ramses Ilarraza, Charles G. Irvin, Kenji Ishihara, Hiromi Iwasaki, Elizabeth A. Jacobsen, David B. Jacoby, Harsha H. Kariyawasam, Atsushi Kato, Howard R. Katz, A. Barry Kay, Elizabeth A. Kelly, Robert Kern, Paneez Khoury, Hirohito Kita, Amy D. Klion, Leo Koenderman, Roland Kolbeck, Martin Krahn, Paige Lacy, Mark C. Lavigne, Laura E. Layland, Alain Le Moine, James J. Lee, Nancy A. Lee, Fanny Legrand, Philippe Lemaitre, Séverine Letuve, Francesca Levi-Schaffer, Nicolas Levy, Ramin Lotfi, Jan Lötvall, Michael Thomas Lotze, Michael P. McGarry, Kelly M. McNagny, Salahaddin Mahmudi-Azer, Steven Maltby, James S. Malter, Anne M. Månsson Kvarnhammar, Annick Massart, Joanne C. Masterson, Kenji Matsumoto, Joerg Mattes, Rossana C.N. Melo, Nestor A. Molfino, Redwan Moqbel, Yasuo Mori, Ariel Munitz, Parameswaran Nair, Josiane Sabbadini Neves, Thomas B. Nutman, Sergei I. Ochkur, S.O. (Wole) Odemuyiwa, Kazuo Ohuchi, Kanami Orihara, Ian D. Pavord, Caroline M. Percopo, Maximilian Plank, Marina Pretolani, Calman Prussin, Catherine Ptaschinski, Madeleine Rådinger, Savita P. Rao, Florian Rieder, Douglas S. Robinson, Helene F. Rosenberg, Marc E. Rothenberg, Florence Roufosse, Robert P. Schleimer, Shauna Schroeder, Gregory D. Scott, Darren W. Sexton, Mi-Kyung Shin, Dagmar Simon, Hans-Uwe Simon, Dirk E. Smith, Neal Spada, Lisa A. Spencer, P. Sriramarao, Alex Straumann, Kiyoshi Takatsu, Anastasya Teplinsky, Alex Thomas, David Traver, Meri K. Tulic, Per Venge, Amanda Waddell, Lori A. Wagner, Garry M. Walsh, Haibin Wang, Andrew J. Wardlaw, Peter F. Weller, Christine Wennerås, Jason J. Xenakis, Yoshiyuki Yamada, Shida Yousefi, Xiang Zhu, and Nives Zimmermann
- Published
- 2013
13. Host defenses to helminths
- Author
-
Subash Babu and Thomas B. Nutman
- Subjects
Host (biology) ,Helminths ,Biology ,Microbiology - Published
- 2013
14. Onchocerciasis
- Author
-
Philip J Cooper and Thomas B Nutman
- Published
- 2013
15. List of Contributors
- Author
-
Jose M Acuin, Rodney D Adam, Tsiri Agbenyega, AM Shamsir Ahmed, Tahmeed Ahmed, S Asad Ali, Gregory M Anstead, George E Armah, Stephen J Aston, Ronald C Ballard, Elizabeth D Barnett, Imelda Bates, Charles W Beadling, Nicholas J Beeching, Michael L Bennish, Caryn Bern, Frank J Bia, Brian H Bird, Allyson K Bloom, Gerard Bodeker, Robert W Bradsher, Nynke van den Broek, Simon Brooker, John T Brooks, W Abdullah Brooks, Philippe Brouqui, Michael Brown, Fabrizio Bruschi, Donald AP Bundy, Danai Bunnag, Benjamin Caballero, Michael V Callahan, Aulasa J Camerlin, Grant L Campbell, Jonathan R Carapetis, Enitan D Carrol, Eric Caumes, Remi N Charrel, Anna M Checkley, Mala Chhabra, Tepirou Chher, Charlotte M Chiong, M Jobayer Chisti, David C Christiani, Bradley A Connor, Edward S Cooper, Philip J Cooper, R Richard Coughlin, John H Cross, Nigel N Cunliffe, Mark Danta, Nicholas PJ Day, Paron Dekumyoy, Nilanthi deSilva, Gregory Deye, Rebecca Dillingham, H Rogier van Doorn, Barbara Doudier, Michel Drancourt, Françoise Dromer, Michael Eddleston, Samer S El-Kamary, Jeremy Farrar, Wafaie Fawzi, Nicholas A Feasey, Vanessa Field, Marc Fischer, Susan Fisher-Hoch, Kevin Forsyth, LeAnne M Fox, Arthur M Friedlander, Gerson Galdos-Cardenas, Hector H Garcia, Lynne S Garcia, Anna-Maria Geretti, Achilleas Gikas, Robert H Gilman, Victor Javier Sanchez Gonzalez, Melita A Gordon, Richard A Gosselin, Stephen M Graham, Alison D Grant, James J Gray, John R Graybill, Bertrand Graz, Stephen Green, Jeffrey K Griffiths, Bruno Gryseels, Duane J Gubler, Rathi Guhadasan, Aron J Hall, Davidson Hamer, David Harley, Jason B Harris, Amy L Hartman, Oliver Hassall, Roderick J Hay, Chris F Heyns, David R Hill, Martin H Hobdell, Caroline M den Hoed, Meredith L Holtz, M Iqbal Hossain, Peter J Hotez, Eric R Houpt, Cynthia R Howard, Chien-Ching Hung, Munirul Islam, Elizabeth Joekes, Victoria Johnston, Sam Kampondeni, Gagandeep Kang, Powel Kazanjian, Jay S Keystone, Wasif Ali Khan, Arthur Y Kim, Christopher L King, Amy D Klion, Richard Knight, Peter James Krause, Sanjeev Krishna, Ernst J Kuipers, Angelle D LaBeaud, David G Lalloo, Xavier De Lamballerie, Saba Lambert, Regina C LaRocque, John Lawrenson, Myron M Levine, Daniel H Libraty, Diana NJ Lockwood, Kinke M Lommerse, Olivier Lortholary, Rogelio López-Vélez, Benjamin A Lopman, David Mabey, Alan J. Magill, Ciro Maguiña, Syed Faisal Mahmood, Kathryn Maitland, Hadi Manji, Barbara J Marston, Anu Mathew, Christine E Mathews, Max Maurin, Paola J Maurtua-Neumann, Philippe Mayaud, Bongani M Mayosi, Joseph B McCormick, Stephen McKew, Susan LF McLellan, Peter C McMinn, Joseph D Mega, Donald E Meier, Matthieu Million, Veena Mittal, Elizabeth M Molyneux, Susan P Montgomery, Pedro Morera, Pedro L Moro, William J Moss, K Darwin Murrell, Osamu Nakagomi, Toyoko Nakagomi, Neha Nanda, James P Nataro, Eileen E Navaro, Ronald C Neafie, Ricardo Negroni, Ann M Nelson, Paul N Newton, Robert Newton, Stuart T Nichol, Francesca F Norman, Marcio RT Nunes, Thomas B Nutman, Richard A Oberhelman, Edward C Oldfield, Eloy E Ordaya, Christopher D Paddock, Slobodan Paessler, Ilias C Papanikolaou, Georgios Pappas, Luc Paris, Philippe Parola, Christopher M Parry, Manish M Patel, Sharon J Peacock, Rosanna Peeling, Hans Persson, Philip J Peters, Jonathan J Phillips, Richard O Phillips, Farah Naz Qamar, Atif Rahman, Jamilla Rajab, Didier Raoult, Michael F Rein, Aurélié Renvoisé, Jean-Marc Reynes, Frank O Richards, John Richens, Anne W Rimoin, Robert Riviello, Ema G Rodrigues, Allan R Ronald, Benjamin M Rosenthal, David Rosmarin, Ernesto Ruiz-Tiben, Edward T Ryan, Debasish Saha, Arturo Saavedra, Peter M Schantz, Tony Schountz, Sandra K Schumacher, James J Sejvar, Aisha Sethi, Kwonjune J Seung, Om Prakash Sharma, Trueman W Sharp, Anuraj H Shankar, Sonya S Shin, David R Shlim, Nicholas J van Sickels, Freddy Sitas, Thomas L Snelling, Cristina Socolovschi, Tom Solomon, J Erin Staples, Robert C Stewart, August Stich, G Thomas Strickland, Kathryn N Suh, Andreas Suhrbier, Khuanchai Supparatpinyo, Catherine G Sutcliffe, Brett E Swierczewski, John L Tarpley, Hugh R Taylor, Terrie Taylor, Harry J Thomas, C Louise Thwaites, Guy E Thwaites, Tejpratap SP Tiwari, Phan Van Tu, Angus W Turner, Edouard Vannier, Pedro FC Vasconcelos, Fransisco Vega-López, Jorge J Velarde, Nicholas J Vietri, Govinda S Visvesvara, Keyur S Vyas, Katie Wakeham, Thomas J Walsh, Mark H Wansbrough-Jones, David A Warrell, Mary J Warrell, Haider J Warraich, George Watt, Yupaporn Wattanagoon, Dorn Watthanakulpanich, Scott C Weaver, Rachel B Webman, Paul J Weidle, Louis M Weiss, Nicholas J White, Christopher JM Whitty, Dana M Woodhall, Stephen G Wright, Ramnik J Xavier, Lihua Xiao, Hongjie Yu, and Anita KM Zaidi
- Published
- 2013
16. Ivermectin
- Author
-
Philip J Cooper and Thomas B Nutman
- Published
- 2013
17. List of contributors
- Author
-
Roshini Sarah Abraham, Cristina Albanesi, Ilias Alevizos, Juan Anguita, Gregory M. Anstead, Cynthia Aranow, Howard A. Austin, Subash Babu, Mark C. Ballow, James E. Balow, David R. Barnidge, John W. Belmont, Gabrielle T. Belz, Dina Ben-Yehuda, Claudia Berek, Timothy Beukelman, Thomas Bieber, Johannes W.J. Bijlsma, Jack J.H. Bleesing, Sarah E. Blutt, Barbara Bohle, Elena Borzova, Prosper N. Boyaka, Brockow Knut, Jacinta Bustamante, Frank Buttgereit, Mary Byrne, Virginia L. Calder, Magda Carneiro-Sampaio, Sebastian Carotta, Jean-Laurent Casanova, Lisa A. Cavacini, Edwin S.L. Chan, Javier Chinen, Tanuja Chitnis, Monique Cho, Lisa Christopher-Stine, Andrew P. Cope, David B. Corry, Tricia Cottrell, Antonio Coutinho, Marco Craveiro, Randy Q. Cron, Jennifer Cuellar-Rodriguez, Marinos C. Dalakas, Stephanie C. de Barros, Blythe H. Devlin, Betty Diamond, Angela Dispenzieri, Terry W. Du Clos, Stéphanie Dupuis-Boisson, Todd N. Eagar, Kim D. Edhegard, George S. Eisenbarth, Craig A. Elmets, Doruk Erkan, Mark B. Feinberg, Erol Fikrig, Thomas A. Fleisher, Andrew P. Fontenot, Luis M. Franco, Alexandra F. Freeman, Anthony J. Frew, Thea Friedman, Kohtaro Fujihashi, Massimo Gadina, Stephen J. Galli, H. Bobby Gaspar, Moshe E. Gatt, M. Eric Gershwin, Kamran Ghoreschi, Susan L. Gillespie, Jörg J. Goronzy, Clive E.H. Grattan, Neil S. Greenspan, Eyal Grunebaum, Gabrielle Haeberli, Russell P. Hall, Robert G. Hamilton, Gregory R. Harriman, Sarfaraz A. Hasni, Arthur Helbling, Melanie Hingorani, Steven M. Holland, Petr L. Hruz, Gabor Illei, John B. Imboden, Shai Izraeli, Elaine S. Jaffe, Caroline Jagobi, Sirpa Jalkanen, Pim Jetanalin, Emmanuelle Jouanguy, Carl H. June, Axel Kallies, Stefan H.E. Kaufmann, Arthur Kavanaugh, Sabiha Khan, Farrah Kheradmand, Samia J. Khoury, Gary A. Koretzky, Robert Korngold, Anna Kovalszki, Douglas B. Kuhns, Robert A. Kyle, Ian R. Lanza, Arian Laurence, Susan J. Lee, Michael J. Lenardo, Arnold I. Levinson, Ofer Levy, David B. Lewis, Dorothy E. Lewis, Sue L. Lightman, Michael D. Lockshin, Michael T. Lotze, Amber Luong, Meggan Mackay, Jean-Luc Malo, Jonathan S. Maltzman, Peter J. Mannon, Michael P. Manns, Mary Louise Markert, Elizabeth A. McCarthy, Douglas R. McDonald, Jerry R. McGhee, Peter C. Melby, Dean D. Metcalfe, Martin Metz, Stephen D. Miller, Anna L. Mitchell, Shruti Mittal, Makoto Miyara, Carolyn Mold, David R. Moller, Scott N. Mueller, Ulrich R. Müller, Philip M. Murphy, Pierre Noel, Luigi Notarangelo, Thomas B. Nutman, Stephen L. Nutt, João B. Oliveira, Chris M. Olson, John J. O'Shea, Sung-Yun Pai, Lavannya Pandit, Mary E. Paul, Simon H.S. Pearce, Erik J. Peterson, Capucine Picard, Werner J. Pichler, Stefania Pittaluga, Anne Puel, Andreas Radbruch, Stephen T. Reece, John D. Reveille, Robert R. Rich, Christine Rivat, Bruce W.S. Robinson, John R. Rodgers, Chaim M. Roifman, Antony Rosen, James T. Rosenbaum, Barry T. Rouse, Scott D. Rowley, Shimon Sakaguchi, Marko Salmi, Harry W. Schroeder, Markus J.H. Seibel, Carlo Selmi, William M. Shafer, Prediman K. Shah, Sushma Shankar, Alan R. Shaw, William T. Shearer, Javed Sheikh, Richard Siegel, Anna Simon, Philip L. Simonian, Gideon P. Smith, Justine R. Smith, Andrew L. Snow, David S. Stephens, John H. Stone, Alex Straumann, Helen C. Su, Louise Swainson, Ewa Szymanska-Mroczek, Naomi Taylor, Adrian J. Thrasher, Laura Timares, Raul M. Torres, Gülbŭ Uzel, Jos W.M. van der Meer, Jeroen C.H. van der Hilst, John Varga, Meryl Waldman, Peter Weiser, Peter F. Weller, Cornelia M. Weyand, Theresa L. Whiteside, Fredrick M. Wigley, Robert J. Winchester, Kajsa Wing, Kathryn Wood, Hui Xu, Shen-Ying Zhang, and Valérie S. Zimmermann
- Published
- 2013
18. Lymphatic Filariasis
- Author
-
James W. Kazura and Thomas B. Nutman
- Subjects
Pathology ,medicine.medical_specialty ,business.industry ,medicine ,business ,medicine.disease ,Lymphatic filariasis - Published
- 2011
19. Contributors
- Author
-
Saad H. Abdalla, Gustavo Olszanski Acrani, Rakesh Aggarwal, Ban Mishu Allos, Miriam J. Alter, Jon K. Andrus, Juana Angel, Gregory M. Anstead, Eduardo Arathoon, Eurico Arruda, Ray R. Arthur, Robert L. Atmar, Patrick Banura, Alan G. Barbour, Alan D.T. Barrett, Dan Bausch, Steven L. Berk, Pascal O. Bessong, Frank J. Bia, Tihana Bicanic, Robert E. Black, Thomas P. Bleck, Andrea K. Boggild, William Bonnez, Joseph S. Bresee, Corrie Brown, Lillian B. Brown, Enrico Brunetti, Fabrizio Bruschi, Amy E. Bryant, Carlos C. (Kent) Campbell, Carlos Castillo-Solorzano, Martin S. Cetron, Ding-Shinn Chen, Pei-Jer Chen, Xiang-Sheng Chen, Thomas Cherian, K.B. Chua, Myron S. Cohen, Graham S. Cooke, Chester R. Cooper, Edward S. Cooper, Christina M. Coyle, John H. Cross†, David A.B. Dance, Mustapha A. Danesi, Chandler R. Dawson, Catherine de Martel, Ciro A. De Quadros, Anastacio de Queiroz Sousa, Nilanthi R. de Silva, Alexandre Leite de Souza, Christoph Dehio, David J. Diemert, Rebecca Dillingham, John E. Donelson, J. Stephen Dumler, Joseph A. Duncan, Herbert L. DuPont, Marlene L. Durand, Mark L. Eberhard, Joshua C. Eby, Charles Edwards, Rachel B. Eidex, Jerrold J. Ellner, Delia A. Enría, Onder Ergonul, Mary K. Estes, Ahmed Hassan Fahal, Paul E. Farmer, A.S.G. Faruque, Charles Feldman, Heinz Feldmann, Kimberley K. Fox, Silvia Franceschi, Manuel A. Franco, Charles F. Fulhorst, Hector H. Garcia, Robert M. Genta, Robert H. Gilman, Roger I. Glass, Jerome Goddard, Eduardo Gotuzzo, John R. Graybill, Harry B. Greenberg, Paul D. Griffiths, Duane J. Gubler, Richard L. Guerrant, Yezid Gutierrez, Erik L. Hewlett, David L. Heymann, David R. Hill, Mei-Shang Ho, Achim M. Hoerauf, Paul S. Hoffman, Stephen L. Hoffman, Michael R. Holbrook, Thomas L. Holland, Donald R. Hopkins, Duane R. Hospenthal, Peter J. Hotez, S. David Hudnall, James M. Hughes, Kao-Pin Hwang, Raul E. Isturiz, Peter B. Jahrling, Shahid Jameel, Selma M.B. Jeronimo, Edward C. Jones-Lopez, Anna Kabanova, Gagandeep Kang, Christopher L. Karp, James W. Kazura, Peter Kern, Gerald T. Keusch, Jay S. Keystone, Mehnaaz S. Khuroo, Mohammad S. Khuroo, Ik-Sang Kim, Charles H. King, Louis V. Kirchhoff, Amy D. Klion, Keith P. Klugman, Dennis J. Kopecko, Margaret Kosek, Frederick T. Koster, Phyllis E. Kozarsky, Thomas G. Ksiazek, Jens H. Kuhn, Albert J. Lastovica, James W. LeDuc, Peter A. Leone, Paul N. Levett, Michael Levin, Myron M. Levine, Aldo A.M. Lima, Gerhard Lindeque, David L. Longworth, David Mabey, J. Dick Maclean†, Alan J. Magill, Ismael Maguilnik, Ciro Maguiña, James H. Maguire, Siddhartha Mahanty, Shinji Makino, Christian W. Mandl, Thomas J. Marrie, Barry J. Marshall, Gregory J. Martin, Tadahiko Matsumoto, Steven D. Mawhorter, James S. McCarthy, Michael R. McGinnis, Paul S. Mead, Wayne M. Meyers, Robert F. Miller, Samuel I. Miller, James N. Mills, Thomas P. Monath, Christopher C. Moore, Thomas A. Moore, J.C. Morrill, J. Glenn Morris, Megan Murray, K. Darwin Murrell, G. Balakrish Nair, Theodore E. Nash, Barnett R. Nathan, Ricardo Negroni, Anne Nicholson-Weller, Marcio Nucci, Thomas B. Nutman, Nigel O’Farrell, Juan P. Olano, Eng Eong Ooi, Luis S. Ortega, Ynés R. Ortega, Mark A. Pallansch, Jean W. Pape, Georgios Pappas, Julie Parsonnet, Geoffrey Pasvol, Sharon J. Peacock, Richard D. Pearson, Rosanna W. Peeling, David A. Pegues, Jacques Pépin, C.J. Peters, Kristine M. Peterson, William A. Petri, Françoise Portaels, José Luiz Proença-Módena, Thomas C. Quinn, G. Raghurama Rao, Didier Raoult, Rino Rappuoli, John H. Rex, Steven J. Reynolds, José M.C. Ribeiro, Emmanuel Roilides, Pierre E. Rollin, Allan R. Ronald, Paul A. Rota, Sharon L. Roy, Ernesto Ruiz-Tiben, Edward T. Ryan, Debasish Saha, Mohammed A. Salam, Amidou Samie, Julius Schachter, Peter M. Schantz, W. Michael Scheld, Elizabeth P. Schlaudecker, David A. Schwartz, Joseph D. Schwartzman, Arlene C. Seña, Daniel J. Sexton, Truman W. Sharp, Wun-Ju Shieh, Shmuel Shoham, Afzal A. Siddiqui, Upinder Singh, David W. Smith, Michael B. Smith, Bonnie L. Smoak, A. George Smulian, Cynthia B. Snider, Tom Solomon, Samba O. Sow, P. Frederick Sparling, Lisa A. Spencer, Lawrence R. Stanberry, J. Erin Staples, Robert Steffen, Theodore S. Steiner, Mark C. Steinhoff, Dennis L. Stevens, Kathryn N. Suh, Khuanchai Supparatpinyo, Paul J. Szaniszlo, Milagritos D. Tapia, Herbert B. Tanowitz, Sam R. Telford, Robert B. Tesh, Nathan M. Thielman, Fernando J. Torres-Vélez, Joseph D. Tucker, Luis M. Valdez, Jesus G. Valenzuela, Diederik van de Beek, Pedro F.C. Vasconcelos, Govinda S. Visvesvara, Victoria Wahl-Jensen, David H. Walker, Douglas S. Walsh, Thomas J. Walsh, David A. Walton, Peter D. Walzer, Cirle A. Warren, Scott C. Weaver, Louis M. Weiss, Peter F. Weller, A. Clinton White, Nicholas J. White, Robert J. Wilkinson, Mary E. Wilson, Murray Wittner, Anita K.M. Zaidi, and Sherif R. Zaki
- Published
- 2011
20. Contributors
- Author
-
Lewis Adams, Anthony J. Alberg, Richard K. Albert, Kurt H. Albertine, Devanand Anantham, Douglas Arenberg, Najib T. Ayas, Ronald C. Balkissoon, John R. Balmes, Srinivas R. Bapoje, Joan Albert Barberà, Peter J. Barnes, Fuad M. Baroody, Margaret R. Becklake, Joshua O. Benditt, Neal L. Benowitz, Paul D. Blanc, Richard C. Boucher, Alfred A. Bove, Elisabeth Brambilla, V. Courtney Broaddus, Kevin K. Brown, Paul G. Brunetta, Jacques Cadranel, David P. Carbone, Bartolome R. Celli, Edward D. Chan, Moira Chan-Yeung, Richard N. Channick, Jean Chastre, Kian Fan Chung, Maria Cirino-Marcano, R. Edward Coleman, Harold R. Collard, Carlyne D. Cool, Jean-François Cordier, Tamera J. Corte, Vincent Cottin, Robert L. Cowie, Robert O. Crapo, Kristina Crothers, Charles L. Daley, Scott F. Davies, Teresa De Marco, Lorenzo Del Sorbo, Gregory P. Downey, Wonder Drake, Roland M. du Bois, James Duffin, Richard M. Effros, Mark D. Eisner, Brett M. Elicker, Armin Ernst, Peter F. Fedullo, Matthew J. Fenton, Daniel Fertel, Hans G. Folkesson, Rodney J. Folz, Andrew P. Fontenot, Joe G.N. Garcia, Gerald F. Gebhart, Thomas J. Giordano, Nicolas Girard, Mark T. Gladwin, Michael B. Gotway, James M. Greenberg, David E. Griffith, Stephen Groshong, Matthew J. Hegewald, Peter M. Henson, Nicholas S. Hill, Philip C. Hopewell, Laurence Huang, Yoshikazu Inoue, Michael D. Iseman, James E. Jackson, Jeffrey R. Jacobson, James R. Jett, Demet Karnak, Midori Kato-Maeda, Mani S. Kavuru, Talmadge E. King, Michael R. Knowles, Kenneth S. Knox, Robert M. Kotloff, Monica Kraft, Elif Kupeli, Stephen E. Lapinsky, Abigail R. Lara, Stephen C. Lazarus, F. Eun-Hyung Lee, Warren L. Lee, Y.C. Gary Lee, Teofilo Lee-Chiong, James F. Lewis, Richard W. Light, Andrew H. Limper, Robert Loddenkemper, John M. Luce, Njira Lugogo, Andrew M. Luks, Charles-Edouard Luyt, Roberto F. Machado, Neil R. MacIntyre, Lisa A. Maier, Fabien Maldonado, Jean-Luc Malo, Erica L. Martin, Thomas R. Martin, Robert J. Mason, Pierre P. Massion, Michael A. Matthay, Richard A. Matthay, Annyce S. Mayer, James McCarthy, F. Dennis McCool, Francis X. McCormack, Dana McGlothlin, Atul C. Mehta, Rosario Menéndez, Alison Morris, Timothy A. Morris, Lake D. Morrison, Marc Moss, Jill Murray, John F. Murray, Jeffrey L. Myers, Jay A. Nadel, Koh Nakata, Thomas S. Neuman, Lee S. Newman, Paul W. Noble, Marc Noppen, Thomas B. Nutman, Thomas G. O’Riordan, Allan I. Pack, Peter D. Paré, David R. Park, Edward F. Patz, Eliot A. Phillipson, Allan Pickens, Grace W. Pien, Frank L. Powell, Bobbi S. Pritt, Loretta G. Que, V. Marco Ranieri, John J. Reilly, Stephen I. Rennard, Susan D. Reynolds, David W.H. Riches, Norman W. Rizk, Bruce W.S. Robinson, Roberto Rodriguez-Roisin, Cecile S. Rose, Charis Roussos, John M. Routes, Lewis J. Rubin, Jonathan M. Samet, Christian Sandrock, George A. Sarosi, Richard T. Sawyer, Gregory A. Schmidt, Robert B. Schoene, Dean E. Schraufnagel, David A. Schwartz, Richard M. Schwartzstein, Marvin I. Schwarz, Moises Selman, John M. Shannon, Steven D. Shapiro, Kenneth E. Shepherd, Claire L. Shovlin, Kathy E. Sietsema, Gerard A. Silvestri, Philip L. Simonian, Arthur S. Slutsky, Gerald C. Smaldone, Eugene J. Sullivan, Erik R. Swenson, Alkis Togias, Antoni Torres, Bruce C. Trapnell, John Treanor, Rubin M. Tuder, George E. Tzelepis, Eric Vallières, Peter D. Wagner, Scott T. Weiss, Athol U. Wells, John B. West, Douglas B. White, John G. Widdicombe, Jeanine P. Wiener-Kronish, Richard Wunderink, James R. Yankaskas, Joseph D.C. Yao, Spyros G. Zakynthinos, Leslie Zimmerman, and Richard L. ZuWallack
- Published
- 2010
21. Immune responses to helminths
- Author
-
Subash Babu and Thomas B. Nutman
- Subjects
Immune system ,Immunology ,Helminths ,Biology - Published
- 2008
22. Contributors
- Author
-
Shizuo Akira, Juan Anguita, Gregory M. Anstead, Cynthia Aranow, Howard A. Austin, Subash Babu, James R. Baker, Christopher S. Baliga, Mark Ballow, James E. Balow, Emil J. Bardana, Matthias D. Becker, John W. Belmont, Dina Ben-Yehuda, Claudia Berek, Thomas Bieber, Johannes W.J. Bijlsma, Jack J.H. Bleesing, Sarah E. Blutt, Elena Borzova, Prosper N. Boyaka, Knut Brockow, Ralph C. Budd, Frank Buttgereit, Virginia L. Calder, Fabio Candotti, Sebastian Carotta, Jean-Laurent Casanova, Marilia Cascalho, Edwin S.L. Chan, Javier Chinen, Monique E. Cho, Lisa Christopher-Stine, Helen L. Collins, Andrew P. Cope, Irene Cortese, Bruce N. Cronstein, Adnan Custovic, Marinos C. Dalakas, Blythe H. Devlin, Betty Diamond, Angela Dispenzieri, Joost P.H. Drenth, Terry W. Du Clos, Mark S. Dykewicz, Todd N. Eagar, George S. Eisenbarth, Charles O. Elson, Doruk Erkan, Mark Feinberg, Erol Fikrig, Alain Fischer, Thomas A. Fleisher, Andrew P. Fontenot, Karen A. Fortner, Anthony J. Frew, Thea M. Friedman, Kohtaro Fujihashi, Stephen J. Galli, Moshe E. Gatt, M. Eric Gershwin, Jörg J. Goronzy, Clive E.H. Grattan, Neil S. Greenspan, Beatrix Grubeck-Loebenstein, Gabrielle Haeberli, Russell P. Hall, Robert G. Hamilton, Gregory R. Harriman, Khaled M. Hassan, Arthur Helbling, David B. Hellmann, Vivian Hernandez-Trujillo, Melanie Hingorani, Steven M. Holland, Henry A. Homburger, McDonald Horne, Gabor Illei, John Imboden, Ken J. Ishii, Shai Izraeli, Elaine S. Jaffe, Sirpa Jalkanen, Carl H. June, Barry D. Kahan, Axel Kallies, Stefan H.E. Kaufmann, Arthur F. Kavanaugh, Gary Koretzky, Robert Korngold, Rania D. Kovaiou, Douglas B. Kuhns, Roger Kurlander, Robert A. Kyle, H. Clifford Lane, Arian Laurence, Françoise Le Deist, Susan J. Lee, Steven J. Lemery, Michael J. Lenardo, Arnold I. Levinson, David B. Lewis, Dorothy E. Lewis, Jay Lieberman, Phil Lieberman, Sue L. Lightman, Michael D. Lockshin, Michael T. Lotze, Meggan Mackay, Jonathan S. Maltzman, Michael P. Manns, Markus Y. Mapara, Susana Marinho, M. Louise Markert, Alberto Martini, Seth L. Masters, Evelina Mazzolari, Henry F. McFarland, Jerry R. McGhee, Frank McKenna, Peter C. Melby, Dean D. Metcalfe, Martin Metz, Joann M. Mican, Stephen D. Miller, Carolyn Mold, David R. Moller, Anthony Montanaro, Scott N. Mueller, Ulrich R. Müller, Philip M. Murphy, Pierre Noel, Luigi D. Notarangelo, Thomas B. Nutman, Stephen L. Nutt, João Bosco de Oliveira, Stephen N. Oliver, Chris M. Olson, John O'shea, Mary E. Paul, Erik J. Peterson, Capucine Picard, Werner J. Pichler, Stanley R. Pillemer, Stefania Pittaluga, Jeffrey L. Platt, Paul H. Plotz, Andreas Radbruch, Angelo Ravelli, John D. Reveille, Robert R. Rich, Margaret E. Rick, Kimberly A. Risma, John R. Rodgers, Antony Rosen, James T. Rosenbaum, Marc E. Rothenberg, Barry T. Rouse, Scott Rowley, Martina Rudelius, Shimon Sakaguchi, Marko Salmi, Ulrich E. Schaible, Harry W. Schroeder, Marvin I. Schwarz, Markus J.H. Seibel, Carlo Selmi, William M. Shafer, Prediman K. Shah, Maryam Shahbaz-Samavi, Alan R. Shaw, William T. Shearer, Scott H. Sicherer, Richard Siegel, Ravinder Jit Singh, Justine R. Smith, Phillip D. Smith, Michael C. Sneller, John W. Steinke, David S. Stephens, John H. Stone, Helen C. Su, Cristina M. Tato, Raul M. Torres, Gülbû Uzel, Jeroen C.H. van der Hilst, Jos W.M. van der Meer, John Varga, José A. Villadangos, Su He Wang, Birgit Weinberger, Peter F. Weller, Cornelia M. Weyand, Fredrick M. Wigley, Robert J. Winchester, Kajsa Wing, Louise J. Young, and Li Zuo
- Published
- 2008
23. Contributors
- Author
-
Susan Anderson, Vernon E. Ansdell, Elizabeth A. Ashley, Howard D. Backer, Jared Baeten, Amy J. Behrman, Thomas N. Bettes, Stephen A. Bezruchka, Rachel A. Bishop, Andrea K. Boggild, Elizabeth L. Brown, Connie Celum, Martin S. Cetron, Carey Farquhar, Stephanie Gelman, Brian D. Gushulak, DeVon Hale, N. Jean Haulman, Thomas R. Hawn, Elaine C. Jong, M. Patricia Joyce, Kevin C. Kain, Sidney N. Klaus, James A. Litch, W. Conrad Liles, Fiona Lovegrove, Sheila M. Mackell, Douglas W. MacPherson, Jeanne M. Marrazzo, Jonathan D. Mayer, Susan L.F. McLellan, Russell McMullen, Rose McQueen, Anne C. Moore, Charles M. Nolan, Thomas B. Nutman, Jon E. Rosenblatt, Christopher Sanford, null Eli Schwartz, Suzanne M. Shepherd, William H. Shoff, David Spach, Alan M. Spira, Mari C. Sullivan, Abinash Virk, Wesley C. Van Voorhis, Richard D. Weller, Nicholas J. White, and Martin S. Wolfe
- Published
- 2008
24. Eosinophilia
- Author
-
Yae-Jean Kim and Thomas B. Nutman
- Subjects
business.industry ,Immunology ,medicine ,Eosinophilia ,medicine.symptom ,business - Published
- 2007
25. Filariasis
- Author
-
Thomas B. Nutman and James W. Kazura
- Subjects
business.industry ,Environmental health ,Medicine ,business ,medicine.disease ,Filariasis - Published
- 2006
26. Loiasis and Mansonella Infections
- Author
-
Thomas B. Nutman and Amy D. Klion
- Subjects
medicine.medical_specialty ,food.ingredient ,food ,business.industry ,Medicine ,Mansonella ,business ,Dermatology - Published
- 2006
27. Filariasis, Lymphatic
- Author
-
Thomas B. Nutman
- Published
- 1998
28. Eosinophil trafficking in allergen-mediated pulmonary inflammation relies on IL-13–driven CCL-11 and CCL-24 production by tissue fibroblasts and myeloid cells
- Author
-
Pedro H. Gazzinelli-Guimaraes, PhD, Dominic P. Golec, PhD, Erik P. Karmele, PhD, Joshua Sciurba, BSc, Pablo Bara-Garcia, MSc, Tom Hill, PhD, Byunghyun Kang, PhD, Sasisekhar Bennuru, PhD, Pamela L. Schwartzberg, MD, and Thomas B. Nutman, MD
- Subjects
Type 2 inflammation ,eosinophils ,allergy ,asthma ,IL-13 signaling ,CCL-11 ,Immunologic diseases. Allergy ,RC581-607 - Abstract
Background: The immunologic mechanisms underlying pulmonary type 2 inflammation, including the dynamics of eosinophil recruitment to the lungs, still need to be elucidated. Objective: We sought to investigate how IL-13–producing TH2 effector cells trigger eosinophil migration in house dust mite (HDM)-driven allergic pulmonary inflammation. Methods: Multiparameter and molecular profiling of murine lungs with HDM-induced allergy was investigated in the absence of IL-13 signaling by using IL-13Rα1–deficient mice and separately through adoptive transfer of CD4+ T cells from IL-5–deficient mice into TCRα–/– mice before allergic inflammation. Results: We demonstrated through single-cell techniques that HDM-driven pulmonary inflammation displays a profile characterized by TH2 effector cell–induced IL-13–dominated eosinophilic inflammation. Using HDM-sensitized IL-13Rα1–/– mice, we found a marked reduction in the influx of eosinophils into the lungs along with a significant downregulation of both CCL-11 and CCL-24. We further found that eosinophil trafficking to the lung relies on production of IL-13–driven CCL-11 and CCL-24 by fibroblasts and Ly6C+ (so-called classical) monocytes. Moreover, this IL-13–mediated eotaxin-dependent eosinophil influx to the lung tissue required IL-5–induced eosinophilia. Finally, we demonstrated that this IL-13–driven eosinophil-dominated pulmonary inflammation was critical for limiting bystander lung transiting Ascaris parasites in a model of allergy and helminth interaction. Conclusion: Our data suggest that IL-5–dependent allergen-specific TH2 effector cell response and subsequent signaling through the IL-13/IL-13Rα1 axis in fibroblasts and myeloid cells regulate the eotaxin-dependent recruitment of eosinophils to the lungs, with multiple downstream consequences, including bystander control of lung transiting parasitic helminths.
- Published
- 2023
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.