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Your search keyword '"Susanne M. Henning"' showing total 5 results
Start Over Author "Susanne M. Henning" Publisher elsevier
5 results on '"Susanne M. Henning"'

1. Xylooligosaccharide supplementation decreases visceral fat accumulation and modulates cecum microbiome in mice

Author

Jianfeng Long, Jieping Yang, Susanne M. Henning, Shih Lung Woo, Mark Hsu, Brenda Chan, David Heber, and Zhaoping Li

Subjects
Xylooligosaccharide, Complex carbohydrate, Diet, Fat accumulation, Microbiota, Nutrition. Foods and food supply, TX341-641
Abstract

Xylooligosaccharide (XOS), an oligosaccharide with great prebiotic potential, has been shown to modulate the gut microbiota. Our aim was to determine the effects of dietary XOS supplementation on body composition, lipid metabolism and intestinal microbiota using a mouse model. Our data showed that XOS dietary supplementation at 2.1 and 7.0% significantly changed the gut microbial composition. A decrease in visceral fat depots, concentration of inflammatory cytokine MCP-1, and abundance of the two most important obesity associated gut microbial phyla Firmicutes and Bacteroidetes were observed with 7% XOS supplementation. No change in blood or liver lipids was observed with both XOS doses. The production of SCFAs in the cecum was increased and relative abundance of Actinobacteria was decreased with supplementation of both doses of XOS. To conclude, XOS supplementation reduced adiposity through decreasing gene expression of markers of adipogenesis and fat synthesis and induced changes in intestinal microbial composition.

Published
2019
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2. Arctigenin inhibits prostate tumor cell growth in vitro and in vivo

Author

Piwen Wang, Walter Solorzano, Tanya Diaz, Clara E. Magyar, Susanne M. Henning, and Jaydutt V. Vadgama

Subjects
Arctigenin, Prostate cancer, SCID mice, Chemoprevention, Phytochemical, Nutrition. Foods and food supply, TX341-641
Abstract

The low bioavailability of most phytochemicals limits their translation to humans. We investigated whether arctigenin, a novel anti-inflammatory lignan from the seeds of Arctium lappa, has favorable bioavailability/potency against prostate cancer. The anticarcinogenic activity of arctigenin was investigated both in vitro using the androgen-sensitive LNCaP and LAPC-4 human prostate cancer cells and pre-malignant WPE1-NA22 cells, and in vivo using xenograft mouse models. Arctigenin at lower doses (

Published
2017
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3. Xylooligosaccharide supplementation decreases visceral fat accumulation and modulates cecum microbiome in mice

Author

Zhaoping Li, Shih Lung Woo, Susanne M. Henning, Mark Hsu, David Heber, Brenda Chan, Jieping Yang, and Jianfeng Long

Subjects
0301 basic medicine, Firmicutes, medicine.medical_treatment, Medicine (miscellaneous), Fat accumulation, Gut flora, Caecum, 03 medical and health sciences, Cecum, 0404 agricultural biotechnology, Xylooligosaccharide, medicine, TX341-641, Microbiome, Food science, 030109 nutrition & dietetics, Nutrition and Dietetics, biology, Chemistry, Nutrition. Foods and food supply, Prebiotic, Microbiota, Lipid metabolism, 04 agricultural and veterinary sciences, biology.organism_classification, 040401 food science, Diet, medicine.anatomical_structure, Food Science, Complex carbohydrate
Abstract

Xylooligosaccharide (XOS), an oligosaccharide with great prebiotic potential, has been shown to modulate the gut microbiota. Our aim was to determine the effects of dietary XOS supplementation on body composition, lipid metabolism and intestinal microbiota using a mouse model. Our data showed that XOS dietary supplementation at 2.1 and 7.0% significantly changed the gut microbial composition. A decrease in visceral fat depots, concentration of inflammatory cytokine MCP-1, and abundance of the two most important obesity associated gut microbial phyla Firmicutes and Bacteroidetes were observed with 7% XOS supplementation. No change in blood or liver lipids was observed with both XOS doses. The production of SCFAs in the cecum was increased and relative abundance of Actinobacteria was decreased with supplementation of both doses of XOS. To conclude, XOS supplementation reduced adiposity through decreasing gene expression of markers of adipogenesis and fat synthesis and induced changes in intestinal microbial composition.

Published
2019

4. Differences in the Tissue Distribution of Green Tea Compared to Black Tea Polyphenols

Author

David Heber, Piwen Wang, and Susanne M. Henning

Subjects
Chemistry, food and beverages, Urine, Epigallocatechin gallate, Green tea, Bioavailability, chemistry.chemical_compound, medicine.anatomical_structure, Biochemistry, Prostate, Polyphenol, medicine, Tissue distribution, Food science, Black tea
Abstract

The polyphenols in green tea (GT) and black tea (BT) are very different due to the different post-harvest processing of the tea leaves, which result in polymerization of GT polyphenols as a result of auto-oxidation. Eighty percent of tea is consumed as BT, while the majority of the literature on the health benefits of tea concerns GT. GT contains higher concentrations of monomeric polyphenols such as epigallocatechin gallate (EGCG), while BT contains polymeric polyphenols such as theaflavins and thearubigins. We have studied the distribution of GT and BT polyphenols in urine and prostate tissue in humans after consumption of brewed GT or BT prior to prostatectomy. Overall, higher concentrations of polyphenols are found in the circulation after GT consumption. While EGCG, 4″-O-MeEGCG and ECG are present in prostate tissue following GT consumption, BT polymers are not found in either blood or prostate tissue. In contrast to human prostate tissue, mouse and rat tissues have detectable levels of both gallated and non-gallated GTPs, suggesting differences in their tissue metabolism of GTPs compared to humans. In both humans and mice, the majority of gallated GTPs are found in the free form, whereas 100% of non-gallated GTPs are conjugated and excreted in the urine. In humans and mice, about 50% of GTPs occur in the methylated form. Future research is needed to investigate how to increase the bioavailability of GTPs.

Published
2013
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5. Contributors

Author

Sami Abbas, Mahmoud AbouLaila, Elio Acquas, Biplab Adhikary, M. Afzal, George Agrogiannis, Selena Ahmed, John P. Alao, Cristina M.M. Almeida, A.R.M. Ruhul Amin, J.P. Andrade, Okezie I. Aruoma, Hiroshi Asaumi, Marco Assunção, Agnieszka Augustyniak, George F. Babcock, Harvey Babich, Theeshan Bahorun, Joanna Bajerska, Susanne Baldermann, Sandip Kumar Bandyopadhyay, Shuvojit Banerjee, Arpita Basu, Saverio Bettuzzi, Udayan Bhattacharya, Anjan Bhattacharyya, Jharna Bhattacharyya, Nirmala Bhoo Pathy, Rebecca L. Bigelow, Dominique Bouglé, Furio Brighenti, Sok-Siya Bun, Eui-Hong Byun, Luca Calani, James A. Cardelli, R. Chalo, Laura Chan, Ruth Chan B.sc., Tak Hang Chan, Hsin-Huei Chang, Kuang-Hua Chang, Raymond Chuen-Chung Chang, Proestos Charalampos, Indu Bhushan Chatterjee, Subrata Chattopadhyay, Chung-Yu Chen, Di Chen, Haixia Chen, Chen Hong-Duo, Junping Chen, Po-Chung Chen, Richie L.C. Chen, Xiaoqiang Chen, Tzong-Jih Cheng, Kai On Chu, Ming-Chien Chyu, Claudia Cimpoiu, Salvatore Cuzzocrea, Asankur Sekhar Das, Dolan Das, Kaushik Das, Eveline A. de Bruin, Elvira De Mejia, Bieke Dejaegher, Sarah Delaney, Jianpeng Dou, Q. Ping Dou, Dorota Dworakowska, Rachel Eckhoff, Tatsuro Egawa, Suzanne Einother, Ramesh Elango, Riad Elias, Nesrine Salah EL-Dine El-Sayed, Lei Feng, Wan Yong Feng, Sandro Fenu, Federico Ferreres, Maria E. Figueira, Lindsey N. Fix, Richard A. Frazier, Michael Frezza, Xing-Hua Gao, Cristina García-Viguera, Sarah A. Gehrke, Pitchairaj Geraldine, Arunava Ghosh, Timo Giesbrecht, Brian Giunta, José Ignacio Gil, Angel Gil-Izquierdo, Ashok K. Giri, Maike Gleichenhagen, Paul S. Grant, Daniel Gyamfi, Taku Hamada, Md Abdul Haque, Yukihiro Hara, Michio Hashimoto, Nobuyuki Hayashi, Tstauya Hayashi, Rong-Rong He, David Heber, Susanne M. Henning, Yasunobu Hirata, Ku Yuen-Shan Ho, Anamaria Hosu, Jean Marie Houghton, Hsien-Yi Hsiao, Bo-Chuan Hsieh, Chun-Hsiung Huang, Dejian Huang, Clara Hiu-Ling Hung, Yueh-Tzu Hung, Daniel H. Hwang, Yuk Hyun-Gyun, Ikuo Igarashi, Mitsuaki Isobe, Grazyna Jasienska, Jan Jeszka, Seon Kim Ji, Li Jianrong, Heiying Jin, Yali Jing, Heiying Jinz, Susan Jordan, Arvin Jundoria, Tatiana Kalinovsky, S. Kamunya, Yoshihiko Kanno, Bappaditya Kanrar, Yung-Hsi Kao, Izet M. Kapetanovic, Maria Kapiszewska, Maria Kapsokefalou, Nikolaos Kavantzas, Bradley B. Keller, Lilian C. Kerio, Sara Anees Khan, Jong-Min Kim, Akiko Kojima-Yuasa, Adam Kokotkiewicz, Michael Komaitis, Govindasamy Kottur, Antonios E. Koutelidakis, Hui-Chen Ku, Ee-Heok Kua, Nikolai Kuhnert, Yow-Chii Kuo, Hiroshi Kurihara, Shinichi Kuriyama, Manuella Lanzett, Anh D. Le, Andy H. Lee, Joo Young Lee, Maw-Rong Lee, Ren-Jye Lee, Seung-Cheol Lee, Viola S.Y. Lee, Na-Na Li, Wei Li, Yuan-Hong Li, Yue-Rong Liang, Chih-Ming Lin, Ching-Ling Lin, Chi-Wei Liu, Hang-Seng Liu, Pengxin Liu, Rosanna Longoni, Mario Lorenz, Jian-Liang Lu, Ya-Ning Lu, Edralin A. Lucas, Wojciech Łuczaj, Maria Luczkiewicz, Amitabye Luximon-Ramma, Paul Lynch, Timothy J. Lyons, Xiao Ma, Mari Maeda-Yamamoto, Symon M. Mahungu, Hidefumi Makabe, Jenny T. Mao, Irvine K. Mariga, T. Maritim, Colin R. Martin, Shuichi Masuda, Isao Matsui-Yuasa, Stephen Karori Mbuthia, Sonia Medina, Aradhana Mehra, Matthias F. Melzig, Anna Merklinger-Gruchala, Mohsen Meydani, Vasile Miclaus, Chandan Mitra, Yohei Miyamoto, Nobuo Momoi, S.A. Mousa, Fhatuwani Nixwell Mudau, Taskeen Mujtaba, Karen L. Mumy, Akira Murakami, Takatoshi Murase, Ramalingam Senthil Murugan, Subramanian Murugesan, Ryozo Nagai, Siddavaram Nagini, Christina Nagle, Kei Nakajima, Vidushi Neergheen-Bhujun, Tze-Pin Ng, Francis Muigai Ngure, Aleksandra Niedzwiecki, Kaijun Niu, M. Nomani, Peter O'Brien, Masahito Ogawa, Eung Seok Oh, Kazushi Okamoto, Evelyne Ollivier, Andrew R. Osterburg, Makoto Otsuki, Chi Pui Pang, Maria Pasalich, Irene Paterniti, Efstratios Patsouris, Ingrid A.-L. Persson, Ante Piljac, Jasenka Piljac-Zegarac, Luís Cristóvão Porto, Mark A. Prendergast, Patcharee Pripdeevech, Shubha Priyamvada, Sirima Puangpraphant, Ramasamy Shanmugasundaram Senthil Kumar, Gregory Raner M., Matthias Rath, Daniele Del Rio, Sherine M. Rizk, Federica Rizzi, Randy J. Robinson, Jorge Rodrigues, M. Waheed Roomi, Colleen Margaret Ross, Abdel-Majeed A. Safer, Sohel Saikat, Andrew E. Sama, Dunja Šamec, Yoichi Sameshima, Alyssa G. Schuck, Baik-Lin Seong, Anubha Sharma, Chwan-Li Shen, Joen-Rong Sheu, Li-Jane Shih, Yuko Shimamura, Dong Moon Shin, Anakalo A. Shitandi, Elżbieta Skrzydlewska, Thomas J. Smith, Jhoti Somanah, Jae-Min Song, Liliana Spina, John Richard Stepp, Calin Stoicov, Guang-Huan Sun, Jun-ichi Suzuki, Hirofumi Tachibana, Jun Tan, Nelson L.S. Tang, Xudong Tang, Joseph Theodore, Philip A. Thomas, Kimimasa Tobita, Naushad A. Toolsee, Jason T.C. Tzen, Cuno S.P.M. Uiterwaal, Samuel Santos Valenca, Leo van Buren, Tracy R. Butler, Pieter C. van der Pijl, Yvan Vander Heyden, Michel Vignes, Stefania Vinci, Francis Wachira, Charlotte M. Walden, Luke Wan, Chi Chiu Wang, Haichao Wang, Piwen Wang, J.K. Wanyoko, Naoharu Watanabe, Jeffrey H. Weisburg, David J. Weiss, Jueng-Tsueng Weng, Michael Wink, Adeline Ik Chian Wong, Sugunya Wongpornchai, Jean Woo, Malgorzata Wozniewicz, Bo-Tsung Wu, Yan Wu, Chen Xiaoqiang, Sudhir Kumar Yadav, Hiroshi Yamada, Ya Ping Yang, Ziyin Yang, Yeh Chien-Chih, Hyun-Gyun Yu, Ahad N.K. Yusufi, Ahmad A. Zahreldin, Hongzheng Zhang, Liang Zhang, Baohong Zhang, Bei Zhang, Chunxia Zhang, Jing-Song Zhang, Lan Zhang, Li Zhang, Qunzhou Zhang, Zheng-Zhu Zhang, Ling Zhao, Keyuan Zhou, Limin Zhou, Dalong Zhu, Shu Zhu, Benno F. Zimmermann, Jean-Marc Zingg, Harriet L. Zuckerbraun, and Zhong Zuo

Published
2013
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