1. Ecotoxicological assessment of Cu-rich acid mine drainage of Sulitjelma mine using zebrafish larvae as an animal model
- Author
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Shubham Varshney, Mikkel Lundås, Prabhugouda Siriyappagouder, Torstein Kristensen, and Pål A. Olsvik
- Subjects
Metals pollution ,Mine drainage ,Fish toxicity ,QPCR ,Behaviour ,Respiration ,Environmental pollution ,TD172-193.5 ,Environmental sciences ,GE1-350 - Abstract
Acid mine drainage (AMD) is widely acknowledged as a substantial threat to the biodiversity of aquatic ecosystems. The present study aimed to study the toxicological effects of Cu-rich AMD from the Sulitjelma mine in zebrafish larvae. The AMD from this mine was found to contain elevated levels of dissolved metals including Mg (46.7 mg/L), Al (20.2 mg/L), Cu (18.3 mg/L), Fe (19.8 mg/L) and Zn (10.6 mg/L). To investigate the toxicological effects, the study commenced by exposing zebrafish embryos to various concentrations of AMD (ranging from 0.75% to 9%) to determine the median lethal concentration (LC50). Results showed that 96 h LC50 for zebrafish larvae following AMD exposure was 2.86% (95% CI: 2.32–3.52%). Based on acute toxicity results, zebrafish embryos (
- Published
- 2024
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