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Background: Age estimation from dental developmental stages is considered comparatively more accurate, reliable and precise than other methods used in forensic sciences. Willems method is the revised version of Demirjian method, based on modified dental maturity scores to estimate age of children in years for both the sexes., Aims: To test the applicability and accuracy level of Willems method of dental age estimation in diverse population samples by quantifying the variations between the chronological and estimated ages of an individual., Methodology: A systematic search of online databases (Pubmed, Scopus, Embase, Medline, Trip and Web of Science) was performed for identifying the articles utilizing Willems dental maturity scaling method for age estimation in children. All the research articles published in peer-reviewed English language journals between 2001 and January 2017 were included for present systematic review and meta-analysis., Results: Out of the total 973 selected articles; thirty one studies were recruited for qualitative analysis and out of them, 15 studies were selected/identified for quantitative and meta-analysis. It was found that Willems method overestimates the age of children to a comparatively lesser extent (-0.04 and -0.02 years) than the Demirjian method (around six months)., Conclusion: Willems method of dental age estimation gives comparatively lesser overestimations of age than other methods reported in the available literature and is thus, accurate and reliable enough to be utilized for forensic purposes., (Copyright © 2017 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.)