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Aquatic plant-derived dissolved organic matter (DOM) in water bodies is an important source of disinfection byproduct (DBP) precursors. It is therefore very important to investigate DBP formation, and the main DBP precursors that enter drinking water during treatment processes. In this study, Lythrum salicaria root extract (LSRE) and Acorus calamus root extract (ACRE) were analyzed. The LSRE and ACRE were chlorinated and disinfected to generate trihalomethanes, haloacetic acids, haloketones, and haloacetaldehydes. The DBP formation potential of LSRE, dominated by humus, was higher than that of Suwannee River natural organic matter (SRNOM), and trichloroacetic acid was the main DBP. It was calculated that 2.09 % of the increased DOC brought by the surface flow wetland planted with emergent aquatic plants, and the contribution rates of TCMFP, DCAAFP and TCAAFP in effluent were 3.34 %, 3.23 % and 3.05 %, respectively. A total of 706 chlorinated-formula were detected by FTICR-MS, among which mono- and di-chlorinated formulae were the most abundant. Macromolecular hydrophobic organics and tannins were the main precursors for LSRE. Unlike LSRE, the DOM composition of ACRE was dominated by protein or aliphatic compounds; therefore, the risk of DBP formation was not as high as that for LSRE. This study is the first to determine the risk of DBP formation associated with aquatic plant root extracts, and confirmed that tannins in plant-derived DOM are more important DBP precursors than lignins., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023. Published by Elsevier B.V.)

In this project, the protective effect of Biebersteinia multifida root extract (BMRE) against corrosion of 1018 low carbon steel (1018LCS) in HCl solutions was appraised by assessing weight loss, electrochemical impedance spectroscopy (EIS), and polarization at 25 °C. The maximum inhibitory efficacy for the concentration of 1 g/l of the BMRE was 92.8% at 25 °C after 2 h and increased to 95.3% after 24 h of immersion. Polarization experiments have shown that the extract in acidic solutions can act as a mixed corrosion inhibitor. The corrosion inhibitory efficacy of BMRE decreased with increasing temperature, and at all temperature settings studied, the adsorption of BMRE molecules on 1018 LCS was consistent with the Langmuir adsorption isotherm. The Scanning Electron Microscopy (SEM) analysis confirmed the protection of 1018 LCS in the acidic solution containing BMRE extract. Quantum chemistry studies of four main constituents of the extract called vasicinone, umbelliferon, scopoletin, and ferulic acid were performed by density functional theory, DFT, in neutral and protonated states. Calculated quantum parameters were used to investigate the active sites and donor-receptor interactions of molecules., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2022 Elsevier B.V. All rights reserved.)

Background: Ashwagandha (Withania somnifera Linn.) a rejuvenative herb has long been used as an immunomodulator in Indian subcontinent. As immunity plays an important role in pathogenesis and treatment of tuberculosis (TB), so role of W. somnifera as an adjuvant has been studied on selected parameter., Method: A randomized, double-blind placebo-control study was conducted in two groups of 60 newly diagnosed sputum smear positive pulmonary TB patients on Directly Observed Treatment - short course (DOTS) regime. W. somnifera root extract or placebo capsules were given as add-on therapy for duration of 12 weeks. Effects on sputum conversion, Hemoglobin (Hb), body weight, Erythrocyte Sedimentation Rate (ESR), RBC counts, WBC counts, CD4 and CD8 counts, Serum Glutamic-Oxaloacetic Transaminase (SGOT), Serum Glutamic-Pyruvic Transaminase (SGPT), serum uric acid and HRQL (Health Related Quality of Life) Index scores were studied., Results: At the end of 8 weeks, sputum conversion was seen in 86.6% patients in study group and 76.6% in placebo group. At the end of 12 weeks a highly significant increase was seen in both CD4 and CD8 counts in study group. A raised SGOT and SGPT levels (>35IU/L) were observed in 16.6% and 33.3% patients in study group; 43.33% and 53.33% in the placebo group of patients. Elevated serum uric acid levels (>6mg/dl) were observed in 20% and 33.33% in study and placebo group respectively. Average gain in HRQL score was better in patients of study group., Conclusion: Use of W. somnifera as an adjuvant in conjunction with anti-TB drugs used as DOTS showed a favorable effect on symptoms and immunological parameters in patients with pulmonary TB., (Copyright © 2017 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved.)

Since the discovery and subsequent widespread use of antibiotics, a variety of bacterial species of human and animal origin have developed numerous mechanisms that render bacteria resistant to some, and in certain cases to nearly all antibiotics, thereby limiting the treatment options and compromising effective therapy. In the present study, the green synthesis of nanoparticles is carried out by the reduction of silver acetate in the presence of crude methanolic root extracts of Diospyros paniculata, a member of family Ebenaceae. The UV-Vis absorption spectrum of the biologically reduced reaction mixture showed the surface plasmon peak at 428 nm, a characteristic peak of silver nanoparticles. X-ray diffraction (XRD) analysis confirmed the face-centered cubic crystalline structure of metallic silver. The average diameter of Ag NPs is about 17 nm from Transmission Electron Microscopy (TEM) which is in good agreement with the average crystallite size (19 nm) calculated from XRD analysis. Further the study has been extended to the antimicrobial activity against test pathogenic Gram (+), Gram (-) bacterial and fungal strains. The biologically synthesized silver nanoparticles showed promising activity against all the tested pathogenic strains and the activity has been enhanced with the increased dose levels., (Copyright © 2016 Elsevier B.V. All rights reserved.)