1. Symptomatic therapy of multiple system atrophy.
- Author
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Rohrer G, Höglinger GU, and Levin J
- Subjects
- Cerebellum physiopathology, Dystonia diagnosis, Humans, Motor Neuron Disease physiopathology, Multiple System Atrophy diagnosis, Pure Autonomic Failure diagnosis, Sleep Wake Disorders diagnosis, Dystonia therapy, Multiple System Atrophy therapy, Pure Autonomic Failure therapy, Sleep Wake Disorders therapy
- Abstract
Multiple system atrophy is a progressive neurodegenerative disease characterized by the association of autonomic failure and a movement disorder that consist of either a hypokinetic movement disorder or a cerebellar syndrome or both. In addition to these core characteristics other movement disorders (e.g. dystonia, myoclonus, spasticity), and neuropsychiatric symptoms (e.g. depression, cognitive dysfunction) may occur in the course of the disease and can severely impair patients' quality of live. To date no causal therapy is available and therefore symptomatic treatment plays a pivotal role in patient care. In this article we provide an overview of frequent clinical symptoms and their symptomatic treatment options., (Copyright © 2017 Elsevier B.V. All rights reserved.)
- Published
- 2018
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