7 results on '"Rodriguez-Granillo, GA"'
Search Results
2. Evaluation of pectus excavatum indexes during standard cardiac magnetic resonance: Potential for single preoperative tool.
- Author
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Viña NA, Carrascosa P, Mogensen VC, Deviggiano A, Bellia-Munzon G, Martinez-Ferro M, and Rodriguez-Granillo GA
- Subjects
- Adult, Female, Funnel Chest surgery, Humans, Male, Preoperative Period, Reproducibility of Results, Retrospective Studies, Thoracic Wall abnormalities, Tomography, X-Ray Computed methods, Young Adult, Funnel Chest diagnosis, Magnetic Resonance Imaging, Cine methods, Thoracic Wall diagnostic imaging, Thoracoplasty
- Abstract
Purpose: Preoperative assessment of patients with pectus excavatum (PE) demands evaluation of malformation indexes, generally with chest computed tomography (CT). In addition, assessment of the cardiac impact of sternal depression has become a rule in high referral centers, thus requiring two independent imaging modalities and use ionizing radiation in a very young population. The objective of this study was to explore the agreement between chest CT and standard cardiac MR (CMR) for the evaluation of chest wall malformation indexes., Methods: We included consecutive patients with PE referred to undergo chest CT and CMR to establish surgical candidacy and/or to define treatment strategies. Both CT and CMR were performed at full-expiration. In both modalities, the Haller index (HI) and the Correction index (CI) were calculated by two independent observers. In CMR, only scout images were used. Agreement was evaluated using intra-class correlation coefficients (ICC)., Results: Fifty patients comprised the study population (median age 19.0 years) and underwent chest CT and CMR within the same month. CMR assessment of chest malformation indexes was reproducible, with a very good inter-observer agreement for HI [ICC 0.93 (0.88-0.96), p < 0.0001] and CI [ICC 0.91 (0.83-0.95), p < 0.0001]. CMR also had a very good agreement with chest CT for HI [ICC 0.90 (0.82-0.94), p < 0.0001] and CI measurements [ICC 0.93 (95% CI 0.88-0.96), p < 0.0001]., Conclusions: We demonstrated an excellent agreement between chest CT and standard CMR for the assessment of chest wall malformations, thus potentially enabling preoperative assessment of PE severity and cardiac involvement with a single diagnostic tool., (Copyright © 2018 Elsevier Inc. All rights reserved.)
- Published
- 2019
- Full Text
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3. Pericardial and visceral, but not total body fat, are related to global coronary and extra-coronary atherosclerotic plaque burden.
- Author
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Rodriguez-Granillo GA, Reynoso E, Capunay C, Carpio J, and Carrascosa P
- Subjects
- Adult, Aged, Aged, 80 and over, Computed Tomography Angiography methods, Coronary Artery Disease epidemiology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Plaque, Atherosclerotic epidemiology, Adipose Tissue diagnostic imaging, Coronary Artery Disease diagnostic imaging, Intra-Abdominal Fat diagnostic imaging, Pericardium diagnostic imaging, Plaque, Atherosclerotic diagnostic imaging
- Abstract
Background: To explore the relationship between coronary and extra-coronary atherosclerotic plaque burden with total and regional fat depots among patients undergoing ECG-gated aortic computed tomography angiography (CTA)., Methods: The subjects of this study comprised a cohort of consecutive patients who underwent ECG-gated thoracoabdominal CTA. We assessed the number of coronary segments with plaques (segment-involvement score, SIS); and the extra-coronary atherosclerotic plaque burden, comprising the aorta and supra-aortic trunks, iliofemoral arteries, and visceral arteries (extra-coronary SS). Total and regional fat volume (FV) were calculated., Results: A total of 2700 vascular segments were evaluated in 90 patients. Obese patients (n = 31, 34%) showed similar coronary SIS (p = 0.41) and extra-coronary SS (p = 0.22) than non-obese patients. General body fat measurements were not related to atherosclerotic plaque burden scores, without associations between coronary or extra-coronary plaque burden and BMI (p = 0.68, and p = 0.91), abdominal circumference (p = 0.13, p = 0.89), total body FV (p = 0.50, p = 0.98), or abdominal FV (p = 0.51, p = 0.99). Pericardial FV was related to coronary SIS (p < 0.0001) and extra-coronary SS (p = 0.008), and visceral FV was related to the coronary SIS (p = 0.006) and extra-coronary SS (p = 0.056). Abdominal subcutaneous fat was inversely related to coronary SIS (p = 0.038) and extra-coronary SS (p = 0.010). Pericardial FV was identified as the only independent predictor of extensive coronary [OR 1.020 (95% CI 1.001-1.039), p = 0.036] and extra-coronary [OR 1.018 (95% CI 1.001-1.036), p = 0.035] plaque burden., Conclusions: In the present study, pericardial and visceral fat were associated with an increased atherosclerotic burden, whereas we identified an inverse relationship between subcutaneous abdominal fat and plaque burden., (Copyright © 2018 Elsevier B.V. All rights reserved.)
- Published
- 2018
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- View/download PDF
4. Dual energy imaging and intracycle motion correction for CT coronary angiography in patients with intermediate to high likelihood of coronary artery disease.
- Author
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Carrascosa P, Deviggiano A, Leipsic JA, Capunay C, De Zan MC, Goldsmit A, and Rodriguez-Granillo GA
- Subjects
- Aged, Algorithms, Female, Humans, Male, Middle Aged, Motion, Reproducibility of Results, Coronary Angiography methods, Coronary Artery Disease diagnostic imaging
- Abstract
We explored whether intracycle motion correction algorithms (MCAs) might be applicable to dual energy computed tomography coronary angiography in patients with intermediate to high likelihood of coronary artery disease. MCA reconstructions were associated with higher interpretability rates (96.7% vs. 87.9%, P<.001), image quality scores (4.12 ± 0.9 vs. 3.76 ± 1.0; P<.0001), and diagnostic performance [area under the curve of 0.95 (95% confidence interval [CI] 0.92-0.97) vs. 0.89 (95% CI 0.86-0.92); P<.0001] compared to conventional reconstructions. In conclusion, application of intracycle MCA reconstructions to dual energy computed tomography acquisitions was feasible and resulted in significantly higher image quality scores, interpretability, and diagnostic performance., (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Published
- 2015
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5. Myocardial signal density levels and beam-hardening artifact attenuation using dual-energy computed tomography.
- Author
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Rodriguez-Granillo GA, Carrascosa P, Cipriano S, de Zan M, Deviggiano A, Capunay C, and Cury RC
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- Aged, Analysis of Variance, Coronary Angiography, Coronary Artery Disease physiopathology, Female, Humans, Male, Middle Aged, Signal-To-Noise Ratio, Artifacts, Coronary Artery Disease diagnostic imaging, Coronary Circulation, Myocardial Perfusion Imaging methods, Tomography, X-Ray Computed methods
- Abstract
The assessment of myocardial perfusion using single-energy (SE) imaging is influenced by beam-hardening artifacts (BHA). We sought to explore the ability of dual-energy (DE) imaging to attenuate the presence of BHA. Myocardial signal density (SD) was evaluated in 2240 myocardial segments (112 for each energy level) and in 320 American Heart Association segments among the SE group. Compared to DE reconstructions at the best energy level, SE acquisitions showed no significant differences overall regarding myocardial SD or signal-to-noise ratio. The segments most commonly affected by BHA showed significantly lower myocardial SD at the lowest energy levels, progressively normalizing at higher energy levels., (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Published
- 2015
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6. Early assessment of myocardial viability by the use of delayed enhancement computed tomography after primary percutaneous coronary intervention.
- Author
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Rodriguez-Granillo GA, Rosales MA, Baum S, Rennes P, Rodriguez-Pagani C, Curotto V, Fernandez-Pereira C, Llaurado C, Risau G, Degrossi E, Doval HC, and Rodriguez AE
- Subjects
- Aged, Biomarkers blood, Creatine Kinase blood, Electrocardiography, Female, Humans, Length of Stay, Male, Middle Aged, Myocardial Infarction diagnostic imaging, Myocardial Infarction physiopathology, Myocardial Reperfusion Injury etiology, Myocardial Reperfusion Injury physiopathology, Myocardium enzymology, Necrosis, Predictive Value of Tests, Recovery of Function, Recurrence, Stroke Volume, Time Factors, Tissue Survival, Tomography, Emission-Computed, Single-Photon, Treatment Outcome, Ventricular Function, Left, Angioplasty, Balloon, Coronary adverse effects, Contrast Media, Coronary Circulation, Myocardial Infarction therapy, Myocardial Reperfusion Injury diagnostic imaging, Myocardium pathology, Tomography, X-Ray Computed
- Abstract
Objectives: We sought to explore the relationship between established parameters of reperfusion and the extent of myocardial damage measured by the delayed enhancement (DE) of iodinated contrast by multidetector computed tomography (MDCT) immediately after primary percutaneous coronary intervention (PCI)., Background: Early detection of myocardial viability should be valuable for risk stratification of patients with reperfused acute myocardial infarction (AMI)., Methods: Consecutive patients without a history of previous AMI who underwent primary PCI for an ST-segment elevation AMI were examined by DE-MDCT without an additional contrast injection immediately after completion of PCI. No medication was administrated to lower the heart rate. Dose modulation lead to an approximate mean radiation dose of 5.5 mSv., Results: Thirty patients constituted the study population. Mean age was 61.4 +/- 15.6 years, 24 (80%) were men, and 4 (13%) were diabetic. Although post-procedural Thrombolysis In Myocardial Infarction (TIMI) flow grade 3 was achieved in all patients, DE was detected in 14 (47%) patients. Age, sex, hypertension, diabetes, smoking history, serum creatinine levels, and pain duration were not associated with the presence of DE. Door-to-balloon time (DE 70.3 +/- 33.6 min vs. non-DE 98.3 +/- 70.7 min, p = 0.19) and lesion crossing time (DE 18.6 +/- 11.4 min vs. non-DE 16.4 +/- 9.6 min, p = 0.58) did not differ between groups. The TIMI myocardial perfusion grade (0 to 1 vs. 2 to 3) after stent implantation and electrocardiogram ST-segment resolution (<50% or >/=50%) were associated with the presence of DE (p = 0.001 and p = 0.02, respectively). Pre-discharge left ventricular ejection fraction was lower in DE than in non-DE patients (44.6 +/- 12.4% vs. 54.1 +/- 10.3%, respectively, p = 0.05). Hospitalization days (DE 5.6 +/- 3.8 vs. non-DE 4.8 +/- 1.0, p = 0.41) and 6-month cardiac events (DE 3 of 14 vs. non-DE 1 of 16, p = 0.22) did not differ between groups., Conclusions: Early detection of myocardial viability immediately after primary PCI by the use of DE-MDCT is related to clinical and angiographic parameters of myocardial reperfusion.
- Published
- 2009
- Full Text
- View/download PDF
7. Application of multislice computed tomography coronary angiography for the diagnostic work-up of acute coronary syndromes.
- Author
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Rodriguez-Granillo GA, Rosales M, and Rodriguez A
- Subjects
- Aged, Humans, Male, Myocardial Infarction diagnostic imaging, Tomography, X-Ray Computed methods
- Abstract
Multislice computed tomography coronary angiography has evolved as an accurate tool to identify the extent, morphology and distribution of significant lesions in the coronary tree of selected patients. More recently, the indications to perform MSCT have been broadened and have been applied in experimented centers to improve the diagnostic work-up of patients admitted with acute coronary syndromes. We report a case were MSCT was applied to define the diagnosis and guide the therapy of a patient admitted with an acute coronary syndrome.
- Published
- 2007
- Full Text
- View/download PDF
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